N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production

Journal of Neurochemistry

Volumn 119, Issue 2, 2011, Pages 354-363

  Asada Utsugi, Megumi ^a   Uemura, Kengo ^a   Noda, Yasuha ^a   Kuzuya, Akira ^a   Maesako, Masato ^a   Ando, Koichi ^a   Kubota, Masakazu ^a   Watanabe, Kiwamu ^a   Takahashi, Makio ^a   Kihara, Takeshi ^a   Shimohama, Shun ^b   Takahashi, Ryosuke ^a   Berezovska, Oksana ^c   Kinoshita, Ayae ^a  

^a KYOTO UNIVERSITY   (Japan)

^b SAPPORO MEDICAL UNIVERSITY   (Japan)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alzheimer's disease; amyloid ; amyloid precursor protein; N cadherin; synapse

Indexed keywords

ADAM10 ENDOPEPTIDASE; ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; NERVE CELL ADHESION MOLECULE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; EMBRYO; ENZYME ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MALE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SYNAPSE;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; BLOTTING, WESTERN; CADHERINS; CELL ADHESION; DIMERIZATION; EXTRACELLULAR SPACE; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; INDICATORS AND REAGENTS; PLASMIDS; TRANSFECTION;

EID: 80053571400     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07364.x     Document Type: Article

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