NMDA receptor activation inhibits α-secretase and promotes neuronal amyloid-β production

Journal of Neuroscience

Volumn 25, Issue 41, 2005, Pages 9367-9377

  Lesné, Sylvain ^a,b   Ali, Carine ^a   Gabriel, Cecília ^a   Croci, Nicole ^d   MacKenzie, Eric T ^a   Glabe, Charles G ^c   Plotkine, Michel ^d   Marchand Verrecchia, Catherine ^d   Vivien, Denis ^a   Buisson, Alain ^a,e  

^a UNIVERSITÉ DE CAEN   (France)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

^e CNRS   (France)

Author keywords

Amyloid; APP; Calmodulin; Glutamate receptors; Neurons; Secretase

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; ALPHA SECRETASE; AMPA RECEPTOR ANTAGONIST; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; COMPLEMENTARY DNA; DIZOCILPINE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLUTAMATE RECEPTOR; LACTATE DEHYDROGENASE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NIMODIPINE; POTASSIUM CHLORIDE; RNA;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN INJURY; CALCIUM SIGNALING; CONTROLLED STUDY; DEPOLARIZATION; EMBRYO; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR;

AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELLS, CULTURED; ENDOPEPTIDASES; EXCITATORY AMINO ACID AGONISTS; HUMANS; MICE; N-METHYLASPARTATE; NEURONS; PROTEASE INHIBITORS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 26844574739     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0849-05.2005     Document Type: Article

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