GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42

EMBO Journal

Volumn 26, Issue 6, 2007, Pages 1702-1712

  Munter, Lisa Marie ^a   Voigt, Philipp ^b   Harmeier, Anja ^a   Kaden, Daniela ^a   Gottschalk, Kay E ^c   Weise, Christoph ^a   Pipkorn, Rüdiger ^d   Schaefer, Michael ^b   Langosch, Dieter ^e   Multhaup, Gerd ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Amyloid A ; Amyloid precursor protein (APP); Dimerization; GxxxG; Secretase

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; GLYCINE; MEMBRANE PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DIMERIZATION; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; NERVE CELL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SYNTHESIS; RISK FACTOR;

ALZHEIMER DISEASE; AMINO ACID MOTIFS; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; BLOTTING, WESTERN; DIMERIZATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; IMMUNOPRECIPITATION; MODELS, MOLECULAR; MUTATION; PEPTIDE FRAGMENTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 33947597857     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601616     Document Type: Article

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