Homodimerization of Amyloid Precursor Protein and Its Implication in the Amyloidogenic Pathway of Alzheimer's Disease

Journal of Biological Chemistry

Volumn 276, Issue 36, 2001, Pages 33923-33929

  Scheuermann, Stefan ^a   Hambsch, Boris ^a   Hesse, Lars ^a,c   Stumm, Joachim ^a   Schmidt, Carsten ^a   Beher, Dirk ^a,d   Bayer, Thomas A ^b   Beyreuther, Konrad ^a   Multhaup, Gerd ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DIMERIZATION; DISEASES; MUTAGENESIS; PROTEINS;

HOMODIMERIZATION;

BIOCHEMISTRY;

AMYLOID PRECURSOR PROTEIN; COLLAGEN; CROSS LINKING REAGENT; CYSTEINE; DISULFIDE; LYSINE; RECOMBINANT PROTEIN;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL CELL; ARTICLE; BINDING SITE; CRYSTALLOGRAPHY; DIMERIZATION; NERVE FIBER GROWTH; NERVE FUNCTION; NEUROPROTECTION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL MEMBRANE; CELL STRAIN COS1; CHEMISTRY; GEL CHROMATOGRAPHY; GENETIC TRANSFECTION; HUMAN; IMMUNOBLOTTING; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

ANIMALIA;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CELL MEMBRANE; CHROMATOGRAPHY, GEL; COLLAGEN; COS CELLS; CROSS-LINKING REAGENTS; CYSTEINE; DIMERIZATION; DISULFIDES; HUMANS; IMMUNOBLOTTING; LYSINE; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035823495     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105410200     Document Type: Article

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