-
1
-
-
8744310788
-
Salicylanilidy - stále aktuální skupina s potenciální antibakteriální aktivitou
-
Vinšová, J.; Imramovský, A. Salicylanilidy - stále aktuální skupina s potenciální antibakteriální aktivitou. Cesk. Slov. Farm., 2004, 53, 294-299.
-
(2004)
Cesk. Slov. Farm.
, vol.53
, pp. 294-299
-
-
Vinšová, J.1
Imramovský, A.2
-
2
-
-
0015233783
-
Mechanism of Action of Uncouplers of Oxidative Phosphorylation
-
Wilson, D.F.; Ting, H.P.; Koppelman, M.S. Mechanism of Action of Uncouplers of Oxidative Phosphorylation. Biochemistry, 1971, 10, 2897-2902.
-
(1971)
Biochemistry
, vol.10
, pp. 2897-2902
-
-
Wilson, D.F.1
Ting, H.P.2
Koppelman, M.S.3
-
3
-
-
0024269714
-
Structural requirements of salicylanilides for uncoupling activity in mitochondria: Quantitative analysis of structureuncoupling relationships
-
Terada, H.; Goto, S.; Yamamoto, K.; Takeuchi, I.; Hamada, Y.; Miyake, K. Structural requirements of salicylanilides for uncoupling activity in mitochondria: quantitative analysis of structureuncoupling relationships. Biochim. Biophys. Acta, 1988, 936, 504-512.
-
(1988)
Biochim. Biophys. Acta.
, vol.936
, pp. 504-512
-
-
Terada, H.1
Goto, S.2
Yamamoto, K.3
Takeuchi, I.4
Hamada, Y.5
Miyake, K.6
-
4
-
-
0037726805
-
Intrinsic and extrinsic uncoupling of oxidative phosphorylation
-
Kadenbach, B. Intrinsic and extrinsic uncoupling of oxidative phosphorylation. Biochim. Biophys. Acta, 2003, 1604, 77-94.
-
(2003)
Biochim. Biophys. Acta.
, vol.1604
, pp. 77-94
-
-
Kadenbach, B.1
-
5
-
-
51449089064
-
Salicylanilides: Selective inhibitors of interleukin-12p40 production
-
Brown, M.E.; Fitzner, J.N.; Stevens, T.; Chin, W.; Wright, C.D.; Boyce, J.P. Salicylanilides: Selective inhibitors of interleukin-12p40 production. Bioorg. Med. Chem., 2008, 16, 8760-8764.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 8760-8764
-
-
Brown, M.E.1
Fitzner, J.N.2
Stevens, T.3
Chin, W.4
Wright, C.D.5
Boyce, J.P.6
-
6
-
-
52249084140
-
Identification of 14-3-3ζ by Chemical Affinity with Salicylanilide Inhibitors of Interleukin-12p40 Production
-
Boyce, J.P.; Brown, M.E.; Chin, W.; Fitzner, J.N.; Paxton, R.J.; Shen, M.; Stevens, T.; Wolfson, M.F.; Wright, C.D. Identification of 14-3-3ζ by Chemical Affinity with Salicylanilide Inhibitors of Interleukin-12p40 Production. Bioconjugate Chem., 2008, 19, 1775-1784.
-
(2008)
Bioconjugate Chem
, vol.19
, pp. 1775-1784
-
-
Boyce, J.P.1
Brown, M.E.2
Chin, W.3
Fitzner, J.N.4
Paxton, R.J.5
Shen, M.6
Stevens, T.7
Wolfson, M.F.8
Wright, C.D.9
-
7
-
-
53449097399
-
Antiallergic and Anti-Inflammatory Effects of a Novel IκB Kinase β Inhibitor, IMD-0354, in a Mouse Model of Allergic Inflammation
-
Sugita, A.; Ogawa, H.; Azuma, M.; Muto, S.; Honjo, A.; Yanagawa, H.; Nishioka, Y.; Tani, K.; Itai, A.; Sone, S. Antiallergic and Anti-Inflammatory Effects of a Novel IκB Kinase β Inhibitor, IMD-0354, in a Mouse Model of Allergic Inflammation. Int. Arch. Allergy Immunol., 2009, 148, 186-198.
-
(2009)
Int. Arch. Allergy Immunol.
, vol.148
, pp. 186-198
-
-
Sugita, A.1
Ogawa, H.2
Azuma, M.3
Muto, S.4
Honjo, A.5
Yanagawa, H.6
Nishioka, Y.7
Tani, K.8
Itai, A.9
Sone, S.10
-
8
-
-
57749105255
-
Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease
-
Edwards, M.R.; Bartlett, N.W.; Clarke, D.; Birrell, M.; Belvisi, M.; Johnston, S.L. Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease. Pharmacol. Ther., 2009, 121, 1-13.
-
(2009)
Pharmacol. Ther.
, vol.121
, pp. 1-13
-
-
Edwards, M.R.1
Bartlett, N.W.2
Clarke, D.3
Birrell, M.4
Belvisi, M.5
Johnston, S.L.6
-
9
-
-
1342310784
-
Regulation of TNF-α and IFN-γ induced CXCL10 expression: Participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease
-
Hardaker, A.L.; Bacon, A.M.; Carlson, K.; Roshak, A.K.; Foley, J.J.; Schmidt, D.B.; Buckley, P.T.; Comegys, M.; Panettieri, R.A.; Sarau, H.M.; Belmonte, K.E. Regulation of TNF-α and IFN-γ induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease. FASEB J., 2003, 17, 191.
-
(2003)
FASEB J
, vol.17
, pp. 191
-
-
Hardaker, A.L.1
Bacon, A.M.2
Carlson, K.3
Roshak, A.K.4
Foley, J.J.5
Schmidt, D.B.6
Buckley, P.T.7
Comegys, M.8
Panettieri, R.A.9
Sarau, H.M.10
Belmonte, K.E.11
-
10
-
-
55949137433
-
Synthesis and anti-inflammatory-analgesic activity of 2́,4́-difluoro-3- (carbamoyl)biphenyl-4-yl benzoates
-
Zhong, G.X.; Chen, L.L.; Li, J.; Hu, W.X.; Qi, M.Y. Synthesis and anti-inflammatory-analgesic activity of 2́,4́-difluoro-3- (carbamoyl)biphenyl-4-yl benzoates. Chin. Chem. Lett., 2008, 19, 1419-1422.
-
(2008)
Chin. Chem. Lett.
, vol.19
, pp. 1419-1422
-
-
Zhong, G.X.1
Chen, L.L.2
Li, J.3
Hu, W.X.4
Qi, M.Y.5
-
11
-
-
0035515999
-
New 5-substituted-1-(2-hydroxybenzoyl)- benzotriazoles, potassium channel activators
-
Biagi, G.; Giorgi, I.; Livi, O.; Scartoni, V.; Barili, P.L.; Calderone, V.; Martinotti, E. New 5-substituted-1-(2-hydroxybenzoyl)- benzotriazoles, potassium channel activators. IV. Farmaco, 2001, 56, 827-834.
-
(2001)
IV. Farmaco.
, vol.56
, pp. 827-834
-
-
Biagi, G.1
Giorgi, I.2
Livi, O.3
Scartoni, V.4
Barili, P.L.5
Calderone, V.6
Martinotti, E.7
-
12
-
-
2942613300
-
Synthesis and biological activity of novel substituted benzanilides as potassium channel activators
-
Biagi, G.; Giorgi, I.; Livi, O.; Nardi, A.; Calderone, V.; Martelli, A.; Martinotti, E.; Salerni, OL. Synthesis and biological activity of novel substituted benzanilides as potassium channel activators. V. Eur. J. Med. Chem., 2004, 39, 491-498.
-
(2004)
V. Eur. J. Med. Chem.
, vol.39
, pp. 491-498
-
-
Biagi, G.1
Giorgi, I.2
Livi, O.3
Nardi, A.4
Calderone, V.5
Martelli, A.6
Martinotti, E.7
Salerni, O.L.8
-
13
-
-
33845397235
-
Structural modifications of benzanilide derivatives, effective potassium channel openers
-
Calderone, V.; Coi, A.; Fiamingo, F.L.; Giorgi, I.; Leonardi, M.; Livi, O.; Martelli, A.; Martinotti, E. Structural modifications of benzanilide derivatives, effective potassium channel openers. X. Eur. J. Med. Chem., 2006, 41, 1421-1429.
-
(2006)
X. Eur. J. Med. Chem.
, vol.41
, pp. 1421-1429
-
-
Calderone, V.1
Coi, A.2
Fiamingo, F.L.3
Giorgi, I.4
Leonardi, M.5
Livi, O.6
Martelli, A.7
Martinotti, E.8
-
14
-
-
9644259011
-
4- Anilinoquinazolines with LavendustinA subunit as inhibitors of epidermal growth factor receptor tyrosine kinase: Syntheses, chemical and pharmacological properties
-
Albuschat, R.; Löwe, W.; Weber, M.; Luger, P.; Jendrossek, V. 4- Anilinoquinazolines with LavendustinA subunit as inhibitors of epidermal growth factor receptor tyrosine kinase: syntheses, chemical and pharmacological properties. Eur. J. Med. Chem., 2004, 39, 1001-1011.
-
(2004)
Eur. J. Med. Chem.
, vol.39
, pp. 1001-1011
-
-
Albuschat, R.1
Löwe, W.2
Weber, M.3
Luger, P.4
Jendrossek, V.5
-
15
-
-
1342279609
-
Salicylanilides as inhibitors of the protein tyrosine kinase epidermal growth factor receptor
-
Liechti, C.; Séquin, U.; Bold, G.; Furet, P.; Meyer, T.; Traxler, P. Salicylanilides as inhibitors of the protein tyrosine kinase epidermal growth factor receptor. Eur. J. Med. Chem., 2004, 39, 11-26.
-
(2004)
Eur. J. Med. Chem.
, vol.39
, pp. 11-26
-
-
Liechti, C.1
Séquin, U.2
Bold, G.3
Furet, P.4
Meyer, T.5
Traxler, P.6
-
16
-
-
27944471274
-
Acryloylamino- salicylanilides as EGFR PTK inhibitors
-
Deng, W.; Guo, Z.; Guo, Y.; Feng, Z.; Juany, Y.; Chu, F. Acryloylamino- salicylanilides as EGFR PTK inhibitors. Bioorg. Med. Chem. Lett., 2006, 16, 469-472.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 469-472
-
-
Deng, W.1
Guo, Z.2
Guo, Y.3
Feng, Z.4
Juany, Y.5
Chu, F.6
-
17
-
-
32944462450
-
SUCI02 inhibits the erbB-2 tyrosine kinase receptor signaling pathway and arrests the cell cycle in G1 phase in breast cancer cells
-
Zhu, X.F.; Wang, J.S.; Cai, L.L.; Zeng, Y.X.; Yang, D. SUCI02 inhibits the erbB-2 tyrosine kinase receptor signaling pathway and arrests the cell cycle in G1 phase in breast cancer cells. Cancer Sci., 2006, 97, 84-89.
-
(2006)
Cancer Sci
, vol.97
, pp. 84-89
-
-
Zhu, X.F.1
Wang, J.S.2
Cai, L.L.3
Zeng, Y.X.4
Yang, D.5
-
18
-
-
38749136234
-
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)
-
Methot, J.L.; Chakravarty, P.K.; Chenard, M.; Close, J.; Cruz, J.C.; Dahlberg, W.K.; Fleming, J.; Hamblett, C.L.; Hamill, J.E.; Harrington, P.; Harsch, A.; Heidebrecht, R.; Hughes, B.; Jung, J.; Kenific, C.M.; Kral, A.M.; Meinke, P.T.; Middleton, R.E.; Ozerova, N.; Sloman, D.L.; Stanton, M.G.; Szewczak, A.A.; Tyagarajan, S.; Witter D.J.; Secristb, J.P.; Miller, TA. Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2). Bioorg. Med. Chem. Lett., 2008, 18, 973-978.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 973-978
-
-
Methot, J.L.1
Chakravarty, P.K.2
Chenard, M.3
Close, J.4
Cruz, J.C.5
Dahlberg, W.K.6
Fleming, J.7
Hamblett, C.L.8
Hamill, J.E.9
Harrington, P.10
Harsch, A.11
Heidebrecht, R.12
Hughes, B.13
Jung, J.14
Kenific, C.M.15
Kral, A.M.16
Meinke, P.T.17
Middleton, R.E.18
Ozerova, N.19
Sloman, D.L.20
Stanton, M.G.21
Szewczak, A.A.22
Tyagarajan, S.23
Witter, D.J.24
Secristb, J.P.25
Miller, T.A.26
more..
-
19
-
-
0032833154
-
Antituberculosis activity of certain antifungal and anthelmintic drugs
-
Sun, Z.; Zhang, Y. Antituberculosis activity of certain antifungal and anthelmintic drugs. Tuber. Lung Dis., 1999, 79, 319-320.
-
(1999)
Tuber. Lung Dis.
, vol.79
, pp. 319-320
-
-
Sun, Z.1
Zhang, Y.2
-
20
-
-
0037355357
-
Relationship between the Structure and Antimycobacterial Activity of Substituted Salicylanilides
-
Waisser, K.; Bureš, O.; Holý, P.; Kuneš, J.; Oswald, R.; Jirásková, L.; Pour, M.; Klimešová, V.; Kubicová, L.; Kaustová, J. Relationship between the Structure and Antimycobacterial Activity of Substituted Salicylanilides. Arch. Pharm. Pharm. Med. Chem., 2003, 1, 53-71.
-
(2003)
Arch. Pharm. Pharm. Med. Chem.
, Issue.1
, pp. 53-71
-
-
Waisser, K.1
Bureš, O.2
Holý, P.3
Kuneš, J.4
Oswald, R.5
Jirásková, L.6
Pour, M.7
Klimešová, V.8
Kubicová, L.9
Kaustová, J.10
-
21
-
-
33751518372
-
The Oriented Development of Antituberculotics: Salicylanilides
-
Waisser, K.; Matyk, J.; Divišová, H.; Husáková, P.; Kuneš, J.; Klimešová, V.; Kaustová, J. The Oriented Development of Antituberculotics: Salicylanilides. Arch. Pharm. Chem. Life Sci., 2006, 339, 616-620.
-
(2006)
Arch. Pharm. Chem. Life Sci.
, vol.339
, pp. 616-620
-
-
Waisser, K.1
Matyk, J.2
Divišová, H.3
Husáková, P.4
Kuneš, J.5
Klimešová, V.6
Kaustová, J.7
-
22
-
-
65349142609
-
New Antituberculotics Originated from Salicylanilides with Promising In vitro Activity against Atypical Mycobacterial Strains
-
Imramovský, A.; Vinšová, J.; Férriz, J.M.; Doležal, R.; Jampílek, J.; Kaustová, J.; Kunc, F. New Antituberculotics Originated from Salicylanilides with Promising In vitro Activity against Atypical Mycobacterial Strains. Bioorg. Med. Chem., 2009, 17, 3572-3579.
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 3572-3579
-
-
Imramovský, A.1
Vinšová, J.2
Férriz, J.M.3
Doležal, R.4
Jampílek, J.5
Kaustová, J.6
Kunc, F.7
-
23
-
-
57749086718
-
Salicylanilide esters of N-protected amino acids as novel antimicrobial agents
-
Imramovský, A.; Vinšová, J.; Férriz, J.M.; Buchta. V.; Jampílek, J. Salicylanilide esters of N-protected amino acids as novel antimicrobial agents. Bioorg. Med. Chem. Lett., 2009, 19, 348-351.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 348-351
-
-
Imramovský, A.1
Vinšová, J.2
Férriz, J.M.3
Buchta, V.4
Jampílek, J.5
-
24
-
-
33846977723
-
Salicylanilide acetates: Synthesis and antibacterial evaluation
-
Vinsova, J.; Imramovsky, A.; Buchta, V.; Ceckova, M.; Dolezal, M.; Staud, F.; Jampilek, J.; Kaustova, J. Salicylanilide acetates: Synthesis and antibacterial evaluation. Molecules, 2007, 12, 1-12.
-
(2007)
Molecules
, vol.12
, pp. 1-12
-
-
Vinsova, J.1
Imramovsky, A.2
Buchta, V.3
Ceckova, M.4
Dolezal, M.5
Staud, F.6
Jampilek, J.7
Kaustova, J.8
-
25
-
-
75149117787
-
Salicylanilide carbamates: Antitubercular agents active against multidrug-resistant Mycobacterium tuberculosis strains
-
Férriz, J.M.; Vávrová, K.; Kunc, F.; Imramovský, A.; Stolaříková, J.; Vavšíková, E.; Vinšová, J. Salicylanilide carbamates: Antitubercular agents active against multidrug-resistant Mycobacterium tuberculosis strains. Bioorg. Med. Chem., 2010, 18, 1054-1061
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 1054-1061
-
-
Férriz, J.M.1
Vávrová, K.2
Kunc, F.3
Imramovský, A.4
Stolaříková, J.5
Vavšíková, E.6
Vinšová, J.7
-
26
-
-
78649327783
-
New amino acid esters of salicylanilides active against MDR-TB and other microbes
-
Krátký, M.; Vinšová, J.; Buchta, V.; Horvati, K.; Bösze, S.; Stolaříková, J. New amino acid esters of salicylanilides active against MDR-TB and other microbes. Eur. J. Med. Chem., 2010, 45, 6106-6113.
-
(2010)
Eur. J. Med. Chem.
, vol.45
, pp. 6106-6113
-
-
-
27
-
-
0032558523
-
New antifungals selected by molecular topology
-
Pastor, L.; Garcia-Domenech, R.; Gálvez, J. New antifungals selected by molecular topology. Bioorg. Med. Chem. Lett., 1998, 8, 2577-2582.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 2577-2582
-
-
Pastor, L.1
Garcia-Domenech, R.2
Gálvez, J.3
-
28
-
-
42149152602
-
The Antimicrobial Activity and Quantitative Structure - Biological Activity Relationships Evaluation of Some Novel 2- Hydroxybenzamide Derivatives
-
Ienacu, I.M.C.; Lupea, A.X.; Hadaruga, D.; Hadaruga, N.; Popescu, I.M. The Antimicrobial Activity and Quantitative Structure - Biological Activity Relationships Evaluation of Some Novel 2- Hydroxybenzamide Derivatives. Rev. Chim., 2008, 59, 247-250.
-
(2008)
Rev. Chim.
, vol.59
, pp. 247-250
-
-
Ienacu, I.M.C.1
Lupea, A.X.2
Hadaruga, D.3
Hadaruga, N.4
Popescu, I.M.5
-
29
-
-
70349256258
-
Synthesis and Antifungal Evaluation of Hydroxy-3- phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Their Thioanalogs
-
Skála, P.; Macháček, M.; Vejsová, M.; Kubicová, L.; Kuneš. J.; Waisser, K. Synthesis and Antifungal Evaluation of Hydroxy-3- phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Their Thioanalogs. J. Heterocyclic Chem., 2009, 46, 873-880.
-
(2009)
J. Heterocyclic Chem.
, vol.46
, pp. 873-880
-
-
Skála, P.1
Macháček, M.2
Vejsová, M.3
Kubicová, L.4
Kuneš, J.5
Waisser, K.6
-
30
-
-
15444355645
-
Substituted Salicylanilides as Inhibitors of Two-Component Regulatory Systems in Bacteria
-
Macielag, M.J.; Demers, J.P.; Fraga-Spano, S.A.; Hlasta, D.J.; Johnson, S.G.; Kanojia, R.M.; Russel, R.K.; Sui, Z.H.; Weidner-Wells, M.A.; Werblood, H.; Foleno, B.D.; Goldschmidt, R.M.; Loeloff, M.J.; Webb, G.C.; Barrett, J.F. Substituted Salicylanilides as Inhibitors of Two-Component Regulatory Systems in Bacteria. J. Med. Chem., 1998, 41, 2939-2945.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 2939-2945
-
-
Macielag, M.J.1
Demers, J.P.2
Fraga-Spano, S.A.3
Hlasta, D.J.4
Johnson, S.G.5
Kanojia, R.M.6
Russel, R.K.7
Sui, Z.H.8
Weidner-Wells, M.A.9
Werblood, H.10
Foleno, B.D.11
Goldschmidt, R.M.12
Loeloff, M.J.13
Webb, G.C.14
Barrett, J.F.15
-
31
-
-
0032555190
-
Novel inhibitors of bacterial two-component systems with Gram positive antibacterial activity: Pharmacophore identification based on the screening hit closantel
-
Hlasta, D.J.; Demers, J.P.; Foleno, B.D.; Fraga-Spano, S.A.; Guan, J.; Hilliard, J.J.; Macielag, M.J.; Ohemeng, K.A.; Sheppard, C.M.; Sui, Z.H.; Webb, G.C.; Weidner-Wells, M.A.; Werblood, H.; Barrett, J.F. Novel inhibitors of bacterial two-component systems with Gram positive antibacterial activity: Pharmacophore identification based on the screening hit closantel. Bioorg. Med. Chem. Lett., 1998, 8, 1923-1928.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 1923-1928
-
-
Hlasta, D.J.1
Demers, J.P.2
Foleno, B.D.3
Fraga-Spano, S.A.4
Guan, J.5
Hilliard, J.J.6
Macielag, M.J.7
Ohemeng, K.A.8
Sheppard, C.M.9
Sui, Z.H.10
Webb, G.C.11
Weidner-Wells, M.A.12
Werblood, H.13
Barrett, J.F.14
-
32
-
-
0032807458
-
Multiple Mechanisms of Action for Inhibitors of Histidine Protein Kinases from Bacterial Two-Component Systems
-
Hilliard, J.J.; Goldschmidt, R.M.; Licata, L.; Baum, E.Z.; Bush, K. Multiple Mechanisms of Action for Inhibitors of Histidine Protein Kinases from Bacterial Two-Component Systems. Antimicrob. Agents Chemother., 1999, 43, 1693-1699.
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 1693-1699
-
-
Hilliard, J.J.1
Goldschmidt, R.M.2
Licata, L.3
Baum, E.Z.4
Bush, K.5
-
33
-
-
22844455188
-
Relationships between the Chemical Structure of Substances and their Antimycobacterial Activity Against Atypical Strains. Part 18. 3-Phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Isosteric 3-Phenylquinazoline-2,4-(1H,3H)-diones
-
Waisser, K.; Macháček, M.; Dostál, H.; Gregor, J.; Kubicová, L.; Klimešová, V.; Kuneš, J.; Palát, K.; Hladůvková, J.; Kaustová, J.; Molmann, U. Relationships between the Chemical Structure of Substances and their Antimycobacterial Activity Against Atypical Strains. Part 18. 3-Phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Isosteric 3-Phenylquinazoline-2,4-(1H,3H)-diones. Collect. Czech Chem. Commun., 1999, 24, 1902-1924.
-
(1999)
Collect. Czech Chem. Commun.
, vol.24
, pp. 1902-1924
-
-
Waisser, K.1
Macháček, M.2
Dostál, H.3
Gregor, J.4
Kubicová, L.5
Klimešová, V.6
Kuneš, J.7
Palát, K.8
Hladůvková, J.9
Kaustová, J.10
Molmann, U.11
-
34
-
-
27944489895
-
Synthesis of novel oxazolidinone derivatives for antibacterial investigation
-
Cui, Y.; Dang, Y.; Yang, Y.; Ji, R. Synthesis of novel oxazolidinone derivatives for antibacterial investigation. Curr. Sci., 2005, 89, 531-534.
-
(2005)
Curr. Sci.
, vol.89
, pp. 531-534
-
-
Cui, Y.1
Dang, Y.2
Yang, Y.3
Ji, R.4
-
35
-
-
33750468980
-
Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening
-
De La Fuente, R.; Sonawane, N.D.; Arumainayagam, D.; Verkman, A.S. Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening. Br. J. Pharmacol., 2006, 149, 551-559.
-
(2006)
Br. J. Pharmacol.
, vol.149
, pp. 551-559
-
-
de la Fuente, R.1
Sonawane, N.D.2
Arumainayagam, D.3
Verkman, A.S.4
-
36
-
-
37849049329
-
Design, Synthesis, and Multivariate Quantitative Structure-Activity Relationship of Salicylanilides - Potent Inhibitors of Type III Secretion in Yersinia
-
Dahlgren, M.K.; Kauppi, A.M.; Olsson, I.M.; Linusson, A.; Elofsson, M. Design, Synthesis, and Multivariate Quantitative Structure-Activity Relationship of Salicylanilides - Potent Inhibitors of Type III Secretion in Yersinia. J. Med. Chem., 2007, 50, 6177-6188.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 6177-6188
-
-
Dahlgren, M.K.1
Kauppi, A.M.2
Olsson, I.M.3
Linusson, A.4
Elofsson, M.5
-
37
-
-
42149152602
-
The Antimicrobial Activity and Quantitative Structure - Biological Activity Relationships Evaluation of Some Novel 2- Hydroxybenzamide Derivatives
-
Ienacu, I.M.C.; Lupea, A.X.; Hadaruga, D.; Hadaruga, N.; Popescu, I.M. The Antimicrobial Activity and Quantitative Structure - Biological Activity Relationships Evaluation of Some Novel 2- Hydroxybenzamide Derivatives. Rev. Chim., 2008, 59, 247-250.
-
(2008)
Rev. Chim.
, vol.59
, pp. 247-250
-
-
Ienacu, I.M.C.1
Lupea, A.X.2
Hadaruga, D.3
Hadaruga, N.4
Popescu, I.M.5
-
38
-
-
33846216497
-
Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA
-
Kurita, M.; Shimauchi, T.; Kobayashi, M.; Atarashi, K.; Mori, K.; Tokura, Y. Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA. J. Dermatol. Sci., 2007, 45, 105-112.
-
(2007)
J. Dermatol. Sci.
, vol.45
, pp. 105-112
-
-
Kurita, M.1
Shimauchi, T.2
Kobayashi, M.3
Atarashi, K.4
Mori, K.5
Tokura, Y.6
-
40
-
-
0037824419
-
Photocontact dermatitis and chloracne: Two major occupational and environmental skin diseases induced by different actions of halogenated chemicals
-
Yamamoto, O.; Tokura, Y. Photocontact dermatitis and chloracne: two major occupational and environmental skin diseases induced by different actions of halogenated chemicals. J. Dermatol. Sci., 2003, 32, 85-94.
-
(2003)
J. Dermatol. Sci.
, vol.32
, pp. 85-94
-
-
Yamamoto, O.1
Tokura, Y.2
-
41
-
-
77949333203
-
A 20-year analysis of previous and emerging allergens that elicit photoallergic contact dermatitis
-
Victor, F.C.; Cohen, D.E.; Soter, N.A. A 20-year analysis of previous and emerging allergens that elicit photoallergic contact dermatitis. J. Am. Acad. Dermatol., 2010, 62, 605-610.
-
(2010)
J. Am. Acad. Dermatol.
, vol.62
, pp. 605-610
-
-
Victor, F.C.1
Cohen, D.E.2
Soter, N.A.3
-
42
-
-
0022653743
-
Susceptibility to genotoxic effects of niclosamide in human peripheral lymphocytes exposed in vitro and in vivo
-
Ostrosky-Wegman, P.; García, G.; Montero, R.; Pérez Romero, B.; Alvarez Chacón, Cortinas de Nava, C. Susceptibility to genotoxic effects of niclosamide in human peripheral lymphocytes exposed in vitro and in vivo. Mutat. Res. Lett., 1986, 173, 81-87.
-
(1986)
Mutat. Res. Lett.
, vol.173
, pp. 81-87
-
-
Ostrosky-Wegman, P.1
García, G.2
Montero, R.3
Pérez Romero, B.4
Alvarez, C.5
de Cortinas Nava, C.6
-
43
-
-
0024500767
-
Genotoxic effects of niclosamide in Aspergillus nidulans
-
de la Torre, R.A.; de la Rúa Barceló, R.; Hernández, G.; Espinosa, J.J.; Cortinas de Nava, C. Genotoxic effects of niclosamide in Aspergillus nidulans. Mutat. Res.-Genet. Tox., 1989, 222, 337-341.
-
(1989)
Mutat. Res.-Genet. Tox.
, vol.222
, pp. 337-341
-
-
de la Torre, R.A.1
de la Rúa Barceló, R.2
Hernández, G.3
Espinosa, J.J.4
de Cortinas Nava, C.5
-
44
-
-
0025941977
-
Mutagenic activity of 2-chloro-4-nitroaniline and 5-chlorosalicylic acid in Salmonella typhimurium - 2 possible metabolites of niclosamide
-
Espinosa-Aguirre, J.J.; Reyes, R.E.; de Nava, C.C. Mutagenic activity of 2-chloro-4-nitroaniline and 5-chlorosalicylic acid in Salmonella typhimurium - 2 possible metabolites of niclosamide. Mut. Res., 1991, 264, 139-145.
-
(1991)
Mut. Res.
, vol.264
, pp. 139-145
-
-
Espinosa-Aguirre, J.J.1
Reyes, R.E.2
de Nava, C.C.3
-
45
-
-
0030586767
-
Comparative genotoxicity of six salicylic acid derivatives in bone marrow cells of mice
-
Girl, A.K.; Adhikari, N.; Khan, K.A. Comparative genotoxicity of six salicylic acid derivatives in bone marrow cells of mice. Mutat. Res., 1996, 370, 1-9.
-
(1996)
Mutat. Res.
, vol.370
, pp. 1-9
-
-
Girl, A.K.1
Adhikari, N.2
Khan, K.A.3
-
46
-
-
34248670871
-
Clastogenic Effects of the Fasciolicides Closantel and Nitroxynil on Mice Somatic and Germ Cells
-
Donya, S.M.; Hassan, E.E. Clastogenic Effects of the Fasciolicides Closantel and Nitroxynil on Mice Somatic and Germ Cells. Cytologia, 2007, 72, 29-36.
-
(2007)
Cytologia
, vol.72
, pp. 29-36
-
-
Donya, S.M.1
Hassan, E.E.2
-
47
-
-
0029739563
-
Structure-Based Design of Achiral, Nonpeptidic Hydroxybenzamide as a Novel P2/P2' Replacement for the Symmetry-Based HIV Protease Inhibitors
-
Randad, R.S.; Lubkowska, L.; Silva, A.M.; Guerin, D.M.A.; Gulnik, S.V.; Yu, B.; Erickson, J.W. Structure-Based Design of Achiral, Nonpeptidic Hydroxybenzamide as a Novel P2/P2' Replacement for the Symmetry-Based HIV Protease Inhibitors. Bioorg. Med. Chem., 1996, 4, 1471-1480.
-
(1996)
Bioorg. Med. Chem.
, vol.4
, pp. 1471-1480
-
-
Randad, R.S.1
Lubkowska, L.2
Silva, A.M.3
Guerin, D.M.A.4
Gulnik, S.V.5
Yu, B.6
Erickson, J.W.7
-
48
-
-
77957073597
-
Antiviral Chemotherapy
-
Keating, M.R. Antiviral Chemotherapy. Princip. Med. Biol., 1998, 9, 529-549.
-
(1998)
Princip. Med. Biol.
, vol.9
, pp. 529-549
-
-
Keating, M.R.1
-
49
-
-
12444289560
-
The road to new antiviral therapies
-
Jerome, K.R. The road to new antiviral therapies. Clin. Appl. Immun. Rev., 2005, 5, 65-76.
-
(2005)
Clin. Appl. Immun. Rev.
, vol.5
, pp. 65-76
-
-
Jerome, K.R.1
-
50
-
-
33747095403
-
Antiviral drug resistance
-
Richman, D.D. Antiviral drug resistance. Antiviral Res., 2006, 71, 117-121.
-
(2006)
Antiviral Res
, vol.71
, pp. 117-121
-
-
Richman, D.D.1
-
51
-
-
67949118684
-
A perspective on antiviral resistence
-
Griffiths, P.D. A perspective on antiviral resistence. J. Clin. Virol., 2009, 46, 3-8.
-
(2009)
J. Clin. Virol.
, vol.46
, pp. 3-8
-
-
Griffiths, P.D.1
-
53
-
-
3042675488
-
Inhibition of Severe Acute Respiratory Syndrome Coronavirus Replication by Niclosamide
-
Wu, C.J.; Jan, J.T.; Chen, C.M.; Hsieh, H.P.; Hwang, D.R.; Liu, H.W.; Liu, C.Y.; Huang, H.W.; Chen, S.C.; Hong, C.F.; Lin, R.K.; Chao, Y.S.; Hsu, J.T.A. Inhibition of Severe Acute Respiratory Syndrome Coronavirus Replication by Niclosamide. Antimicrob. Agents Chemother., 2004, 48, 2693-2696.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 2693-2696
-
-
Wu, C.J.1
Jan, J.T.2
Chen, C.M.3
Hsieh, H.P.4
Hwang, D.R.5
Liu, H.W.6
Liu, C.Y.7
Huang, H.W.8
Chen, S.C.9
Hong, C.F.10
Lin, R.K.11
Chao, Y.S.12
Hsu, J.T.A.13
-
54
-
-
34548125311
-
Specific Plant Terpenoids and Lignoids Possess Potent Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus
-
Wen, C.C.; Kuo, Y.H.; Jan, J.T.; Liang, P.H.; Wang, S.Y.; Liu, H.G.; Lee, C.K.; Chang, S.T.; Kuo, C.J.; Lee, S.S.; Hou, C.C.; Hsiao, P.W.; Chien, S.C.; Shyur, L.F.; Yang, N.S. Specific Plant Terpenoids and Lignoids Possess Potent Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus. J. Med. Chem., 2007, 50, 4087-4095.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 4087-4095
-
-
Wen, C.C.1
Kuo, Y.H.2
Jan, J.T.3
Liang, P.H.4
Wang, S.Y.5
Liu, H.G.6
Lee, C.K.7
Chang, S.T.8
Kuo, C.J.9
Lee, S.S.10
Hou, C.C.11
Hsiao, P.W.12
Chien, S.C.13
Shyur, L.F.14
Yang, N.S.15
-
55
-
-
2142657824
-
Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs
-
Zhang, X.W.; Yap, Y.L. Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs. Bioorg. Med. Chem., 2004, 12, 2517-2521.
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 2517-2521
-
-
Zhang, X.W.1
Yap, Y.L.2
-
56
-
-
21244442337
-
Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease
-
Shie, J.J.; Fang, J.M.; Kuo, C.J.; Kuo, T.H.; Liang, P.H.; Huang, H.J.; Yang, W.B.; Lin, C.H.; Chen, J.L.; Wu, Y.T.; Wong, C.H. Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease. J. Med. Chem., 2005, 48, 4469-4473.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 4469-4473
-
-
Shie, J.J.1
Fang, J.M.2
Kuo, C.J.3
Kuo, T.H.4
Liang, P.H.5
Huang, H.J.6
Yang, W.B.7
Lin, C.H.8
Chen, J.L.9
Wu, Y.T.10
Wong, C.H.11
-
57
-
-
67650080312
-
Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death
-
Zhu, P.J.; Hobson, J.P.; Southall, N.; Qiu, C.; Thomas, C.J.; Lu, J.; Inglese, J.; Zheng, W.; Leppla, S.H.; Bugge, T.H.; Austin, C.P; Liu, S. Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death. Bioorg. Med. Chem., 2009, 17, 5139-5145.
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 5139-5145
-
-
Zhu, P.J.1
Hobson, J.P.2
Southall, N.3
Qiu, C.4
Thomas, C.J.5
Lu, J.6
Inglese, J.7
Zheng, W.8
Leppla, S.H.9
Bugge, T.H.10
Austin, C.P.11
Liu, S.12
-
58
-
-
33847011311
-
Pharmacokinetics of Anti-SARS-CoV Agent Niclosamide and Its Analogs in Rats
-
Chang, Y.W.; Yeh, T.K.; Lin, K.T.; Chen, W.C.; Yao, H.T.; Lan, S.J.; Wu, Y.S.; Hsieh, H.P.; Chen, C.M.; Chen, C.T. Pharmacokinetics of Anti-SARS-CoV Agent Niclosamide and Its Analogs in Rats. J. Food Drug Anal., 2006, 14, 329-333.
-
(2006)
J. Food Drug Anal.
, vol.14
, pp. 329-333
-
-
Chang, Y.W.1
Yeh, T.K.2
Lin, K.T.3
Chen, W.C.4
Yao, H.T.5
Lan, S.J.6
Wu, Y.S.7
Hsieh, H.P.8
Chen, C.M.9
Chen, C.T.10
-
59
-
-
33744460794
-
Inhibition of Human Coronavirus NL63 Infection at Early Stages of the Replication Cycle
-
Pyrc, K.; Bosch, B.J.; Berkhout, B.; Jebbink, M.F.; Dijkman, R.; Rottier, P.; van der Hoek, L. Inhibition of Human Coronavirus NL63 Infection at Early Stages of the Replication Cycle. Antimicrob. Agents Chemother., 2006, 50, 2000-2008.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 2000-2008
-
-
Pyrc, K.1
Bosch, B.J.2
Berkhout, B.3
Jebbink, M.F.4
Dijkman, R.5
Rottier, P.6
van der Hoek, L.7
-
60
-
-
62949189676
-
Amide-containing diketoacids as HIV-1 integrase inhibitors: Synthesis, structure-activity relationship analysis, and biological activity
-
Li, H.C.; Wang, C.; Sanchez, T.; Tan, Y.; Jiang, C.; Neamati, N.; Zhao, G. Amide-containing diketoacids as HIV-1 integrase inhibitors: Synthesis, structure-activity relationship analysis, and biological activity. Bioorg. Med. Chem., 2009, 17, 2913-2919.
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 2913-2919
-
-
Li, H.C.1
Wang, C.2
Sanchez, T.3
Tan, Y.4
Jiang, C.5
Neamati, N.6
Zhao, G.7
-
61
-
-
77954705120
-
Drugs for AIDS
-
Ray, S.; Fatima, Z.; Saxena, A. Drugs for AIDS. Mini-Rev. Med. Chem., 2010, 10, 147-161.
-
(2010)
Mini-Rev. Med. Chem.
, vol.10
, pp. 147-161
-
-
Ray, S.1
Fatima, Z.2
Saxena, A.3
-
62
-
-
0033821651
-
Identification of HIV-1 Integrase Inhibitors via Three-Dimensional Database Searching Using ASV and HIV-1 Integrases as Targets
-
Chen, I.J.; Neamati, N.; Nicklaus, M.C.; Orr, A.; Anderson, L.; Barchi, J.J.; Kelley, J.A.; Pommier, Y.; MacKerell, A.D. Identification of HIV-1 Integrase Inhibitors via Three-Dimensional Database Searching Using ASV and HIV-1 Integrases as Targets. Bioorg. Med. Chem., 2000, 8, 2385-2398.
-
(2000)
Bioorg. Med. Chem.
, vol.8
, pp. 2385-2398
-
-
Chen, I.J.1
Neamati, N.2
Nicklaus, M.C.3
Orr, A.4
Anderson, L.5
Barchi, J.J.6
Kelley, J.A.7
Pommier, Y.8
Mackerell, A.D.9
-
63
-
-
34547108566
-
New Developments in Diketo-Containing Inhibitors of HIV-1 Integrase
-
Zhao, G.; Wang, C.; Liu, C.; Lou, H. New Developments in Diketo-Containing Inhibitors of HIV-1 Integrase. Mini-Rev. Med. Chem., 2007, 7, 707-725.
-
(2007)
Mini-Rev. Med. Chem.
, vol.7
, pp. 707-725
-
-
Zhao, G.1
Wang, C.2
Liu, C.3
Lou, H.4
-
64
-
-
14444276046
-
Salicylhydrazine-Containing Inhibitors of HIV-1 Integrase: Implication for a Selective Chelation in the Integrase Active Site
-
Neamati, N.; Hong, H.; Owen, J.M.; Sunder, S.; Winslow, H.E.; Christensen, J.L.; Zhao, H.; Burke, T.R.; Milne, G.W.A.; Pommier, Y. Salicylhydrazine-Containing Inhibitors of HIV-1 Integrase: Implication for a Selective Chelation in the Integrase Active Site. J. Med. Chem., 1998, 41, 3202-3209.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 3202-3209
-
-
Neamati, N.1
Hong, H.2
Owen, J.M.3
Sunder, S.4
Winslow, H.E.5
Christensen, J.L.6
Zhao, H.7
Burke, T.R.8
Milne, G.W.A.9
Pommier, Y.10
-
65
-
-
37849020692
-
Madurahydroxylactone Derivatives as Dual Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and RNase H
-
Marchand, C.; Beutler, J.A.; Wamiru, A.; Budihas, S.; Möllmann, U.; Heinisch, L.; Mellors, J.W.; Le Grice, S.F.; Pommier, Y. Madurahydroxylactone Derivatives as Dual Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and RNase H. Antimicrob. Agents Chemother., 2008, 52, 361-364.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 361-364
-
-
Marchand, C.1
Beutler, J.A.2
Wamiru, A.3
Budihas, S.4
Möllmann, U.5
Heinisch, L.6
Mellors, J.W.7
Le Grice, S.F.8
Pommier, Y.9
-
66
-
-
0037468526
-
Design, Synthesis, SAR, and Molecular Modeling Studies of Acylthiocarbamates: A Novel Series of Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Structurally Related to Phenethylthiazolylthiourea Derivatives
-
Ranise, A.; Spallarossa, A.; Schenone, S.; Bruno, O.; Bondavalli, F.; Vargiu, L.; Marceddu, T.; Mura, M.; La Colla, P.; Pani, A. Design, Synthesis, SAR, and Molecular Modeling Studies of Acylthiocarbamates: A Novel Series of Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Structurally Related to Phenethylthiazolylthiourea Derivatives. J. Med. Chem., 2003, 46, 768-781.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 768-781
-
-
Ranise, A.1
Spallarossa, A.2
Schenone, S.3
Bruno, O.4
Bondavalli, F.5
Vargiu, L.6
Marceddu, T.7
Mura, M.8
la Colla, P.9
Pani, A.10
-
67
-
-
0031047399
-
The Human Immunodeficiency Virus Type 1 (HIV-1) Nucleocapsid Protein Zinc Ejection Activity of Disulfide Benzamides and Benzisothiazolones: Correlation with Anti-HIV and Virucidal Activities
-
Tummino, P.J.; Harvey, P.J.; McQuade, T.; Domagala, J.; Gogliotti, R.; Sanchez, J.; Song, Y.; Hupe, D. The Human Immunodeficiency Virus Type 1 (HIV-1) Nucleocapsid Protein Zinc Ejection Activity of Disulfide Benzamides and Benzisothiazolones: Correlation with Anti-HIV and Virucidal Activities. Antimicrob. Agents Chemother., 1997, 41, 394-400.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 394-400
-
-
Tummino, P.J.1
Harvey, P.J.2
McQuade, T.3
Domagala, J.4
Gogliotti, R.5
Sanchez, J.6
Song, Y.7
Hupe, D.8
-
68
-
-
12144260229
-
Control of Hepatitis C: A Medicinal Chemistry Perspective
-
Gordon, C.P.; Keller, P.A. Control of Hepatitis C: A Medicinal Chemistry Perspective. J. Med. Chem., 2005, 48, 1-20.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 1-20
-
-
Gordon, C.P.1
Keller, P.A.2
-
69
-
-
77954637045
-
-
Patent WO 2009/039127, March 26
-
Wagner, R.; Tufano, M.D.; Stewart, K.D.; Rockway, T.W.; Randolph, J.T.; Pratt, J.K.; Motter, C.E.; Maring, C.J.; Longenecker, K.L.; Liu, Y.; Liu, D.; Krueger, A.C.; Kati, W.M.; Hutchinson, D.K.; Huang, P.P.; Flentge, C.A.; Donner, P.L.; Degoey, D.A.; Betebenner, D.A.; Barnes, D.M.; Chen, S.; Franczyk II, T.S.; Gao, Y.; Haight, A.R.; Hengeveld, J.E.; Henry, R.F.; Kotecki, B.J.; Lou, X.; Sarris, K.; Zhang, G.G.Z. Uracil or thymine derivative for treating hepatitis C. Patent WO 2009/039127, March 26, 2009.
-
(2009)
Uracil Or Thymine Derivative for Treating Hepatitis C
-
-
Wagner, R.1
Tufano, M.D.2
Stewart, K.D.3
Rockway, T.W.4
Randolph, J.T.5
Pratt, J.K.6
Motter, C.E.7
Maring, C.J.8
Longenecker, K.L.9
Liu, Y.10
Liu, D.11
Krueger, A.C.12
Kati, W.M.13
Hutchinson, D.K.14
Huang, P.P.15
Flentge, C.A.16
Donner, P.L.17
Degoey, D.A.18
Betebenner, D.A.19
Barnes, D.M.20
Chen, S.21
Franczyk II, T.S.22
Gao, Y.23
Haight, A.R.24
Hengeveld, J.E.25
Henry, R.F.26
Kotecki, B.J.27
Lou, X.28
Sarris, K.29
Zhang, G.G.Z.30
more..
-
70
-
-
67650526658
-
Current and future treatment options for HCV
-
Kronenberger, B.; Zeuzem, S. Current and future treatment options for HCV. Ann. Hepatol., 2009, 8, 103-112.
-
(2009)
Ann. Hepatol.
, vol.8
, pp. 103-112
-
-
Kronenberger, B.1
Zeuzem, S.2
-
71
-
-
33846207539
-
Cell-Based, High-Throughput Screen for Small Molecule Regulators of Hepatitis C Virus Replication
-
Kim, S.S.; Peng, L.F.; Lin, W.; Choe, W.; Sakamoto, N.; Schreiber, S.L.; Chung, R.T. A Cell-Based, High-Throughput Screen for Small Molecule Regulators of Hepatitis C Virus Replication. Gastroenterology, 2007, 132, 311-320.
-
(2007)
Gastroenterology
, vol.132
, pp. 311-320
-
-
Kim, S.S.1
Peng, L.F.2
Lin, W.3
Choe, W.4
Sakamoto, N.5
Schreiber, S.L.6
Chung, R.T.A.7
-
72
-
-
0030777974
-
Novel hepatitis C virus protease inhibitors: 2,4,6-trihydroxy, 3-nitro-benzamide derivatives
-
Sudo, K.; Matsumoto, Y.; Matsushima, M.; Konno, K.; Shimotohno, K.; Shigeta, S.; Yokota, T. Novel hepatitis C virus protease inhibitors: 2,4,6-trihydroxy, 3-nitro-benzamide derivatives. Antiviral Chem. Chemother., 1997, 8, 541-544.
-
(1997)
Antiviral Chem. Chemother.
, vol.8
, pp. 541-544
-
-
Sudo, K.1
Matsumoto, Y.2
Matsushima, M.3
Konno, K.4
Shimotohno, K.5
Shigeta, S.6
Yokota, T.7
-
73
-
-
0031954546
-
Novel hepatitis C virus protease inhibitors: 2,4,6- trihydroxy, 3-nitro-benzamide derivatives
-
errata
-
Sudo, K.; Matsumoto, Y.; Matsushima, M.; Konno, K.; Shimotohno, K.; Shigeta, S.; Yokota, T. Novel hepatitis C virus protease inhibitors: 2,4,6- trihydroxy, 3-nitro-benzamide derivatives. Antiviral Chem. Chemother., 1998, 9, 186. (errata)
-
(1998)
Antiviral Chem. Chemother.
, vol.9
, pp. 186
-
-
Sudo, K.1
Matsumoto, Y.2
Matsushima, M.3
Konno, K.4
Shimotohno, K.5
Shigeta, S.6
Yokota, T.7
-
74
-
-
0032536094
-
Non-peptide inhibitors of HCV serine proteinase
-
Kakiuchi, N.; Komoda, Y.; Komoda, K.; Takeshita, N.; Okada, S.; Tani, T.; Shimotohno, K. Non-peptide inhibitors of HCV serine proteinase. FEBS Lett., 1998, 421, 217-220.
-
(1998)
FEBS Lett
, vol.421
, pp. 217-220
-
-
Kakiuchi, N.1
Komoda, Y.2
Komoda, K.3
Takeshita, N.4
Okada, S.5
Tani, T.6
Shimotohno, K.7
-
75
-
-
44149125517
-
Identification of halosalicylamide derivatives as a novel class of allosteric inhibitors of HCV NS5B polymerase
-
Liu, Y.; Donner, P.L.; Pratt, J.K.; Jiang, W.W.; Ng, T.; Gracias, V.; Baumeister, S.; Wiedeman, P.E.; Traphagen, L.; Warrior, U.; Maring, C.; Kati, W.M.; Djuric, S.W.; Molla, A. Identification of halosalicylamide derivatives as a novel class of allosteric inhibitors of HCV NS5B polymerase. Bioorg. Med. Chem. Lett., 2008, 18, 3173-3177.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 3173-3177
-
-
Liu, Y.1
Donner, P.L.2
Pratt, J.K.3
Jiang, W.W.4
Ng, T.5
Gracias, V.6
Baumeister, S.7
Wiedeman, P.E.8
Traphagen, L.9
Warrior, U.10
Maring, C.11
Kati, W.M.12
Djuric, S.W.13
Molla, A.14
-
76
-
-
67549114814
-
Serological microarray for detection of HSV-1, HSV-2, VZV, and CMV antibodies
-
Jääskeläinen, A.J.; Moilanen, K.; Bühler, S.; Lappalainen, M.; Vapalahti, O.; Vaheri, A.; Piiparinen, H. Serological microarray for detection of HSV-1, HSV-2, VZV, and CMV antibodies. J. Virol. Methods, 2009, 160, 167-171.
-
(2009)
J. Virol. Methods.
, vol.160
, pp. 167-171
-
-
Jääskeläinen, A.J.1
Moilanen, K.2
Bühler, S.3
Lappalainen, M.4
Vapalahti, O.5
Vaheri, A.6
Piiparinen, H.7
-
77
-
-
80052250872
-
-
Patent WO 00/34260, June 15
-
Bloom, J.D.; Curran, K.J.; Digrandi, M.J.; Dushin, R.G.; Lang, S.A.; Norton, E.B.; Ross, A.A.; O'Hara, B.M. Alpha-methylbenzylcontaining thiourea derivatives containing a phenylenediamine group, useful as inhibitors of herpes viruses. Patent WO 00/34260, June 15, 2000.
-
(2000)
Alpha-methylbenzylcontaining Thiourea Derivatives Containing a Phenylenediamine Group, Useful as Inhibitors of Herpes Viruses
-
-
Bloom, J.D.1
Curran, K.J.2
Digrandi, M.J.3
Dushin, R.G.4
Lang, S.A.5
Norton, E.B.6
Ross, A.A.7
O'Hara, B.M.8
-
78
-
-
80052206153
-
-
Patent WO 00/34238, June 15
-
Bloom, J.D.; Curran, K.J.; Digrandi, M.J.; Dushin, R.G.; Lang, S.A.; Norton, E.B.; Ross, A.A.; O'Hara, B.M. Benzamidecontaining aryl thiourea derivatives useful as inhibitors of herpes viruses. Patent WO 00/34238, June 15, 2000.
-
(2000)
Benzamidecontaining Aryl Thiourea Derivatives Useful as Inhibitors of Herpes Viruses
-
-
Bloom, J.D.1
Curran, K.J.2
Digrandi, M.J.3
Dushin, R.G.4
Lang, S.A.5
Norton, E.B.6
Ross, A.A.7
O'Hara, B.M.8
-
79
-
-
0030855938
-
Design and discovery of HIV-1 integrase inhibitors
-
Neamati, N.; Sunder, S.; Pommier, Y. Design and discovery of HIV-1 integrase inhibitors. Drug Discov. Today, 1997, 2, 487-498.
-
(1997)
Drug Discov. Today
, vol.2
, pp. 487-498
-
-
Neamati, N.1
Sunder, S.2
Pommier, Y.3
-
80
-
-
0030933554
-
Discovery of HIV-1 Integrase Inhibitors by Pharmacophore Searching
-
Hong, H.; Neamati, N.; Wang, S.; Nicklaus, M.C.; Mazumder, A.; Zhao, H.; Burke, T.R.; Pommier, Y, Milne, G.W.A. Discovery of HIV-1 Integrase Inhibitors by Pharmacophore Searching. J. Med. Chem., 1997, 40, 930-936.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 930-936
-
-
Hong, H.1
Neamati, N.2
Wang, S.3
Nicklaus, M.C.4
Mazumder, A.5
Zhao, H.6
Burke, T.R.7
Pommier, Y.8
Milne, G.W.A.9
-
81
-
-
0030946320
-
Hydrazide-Containing Inhibitors of HIV-1 Integrase
-
Zhao, H.; Neamati, N.; Sunder, S.; Hong, H.; Wang, S.; Milne, G.W.A.; Pommier, Y.; Burke, TR. Hydrazide-Containing Inhibitors of HIV-1 Integrase. J. Med. Chem., 1997, 40, 937-941.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 937-941
-
-
Zhao, H.1
Neamati, N.2
Sunder, S.3
Hong, H.4
Wang, S.5
Milne, G.W.A.6
Pommier, Y.7
Burke, T.R.8
-
82
-
-
0031765781
-
Identification of HIV-1 integrase inhibitors based on a four-point pharmacophore
-
Hong, H.; Neamati, N.; Winslow, H.E.; Christensen, J.L.; Orr, A.; Pommier, Y.; Milne, G.W.A. Identification of HIV-1 integrase inhibitors based on a four-point pharmacophore. Antiviral Chem. Chemother., 1998, 9, 461-472.
-
(1998)
Antiviral Chem. Chemother.
, vol.9
, pp. 461-472
-
-
Hong, H.1
Neamati, N.2
Winslow, H.E.3
Christensen, J.L.4
Orr, A.5
Pommier, Y.6
Milne, G.W.A.7
-
83
-
-
0031746876
-
Structure-Activity Relationship of HIV-1 Protease Inhibitors Containing AHPBA. Part III: Modification of P2 Site
-
Takashiro, E.; Watanabe, T.; Nitta, T.; Kasuya, A.; Miyamoto, S.; Ozawa, Y.; Yagi, R.; Nishigaki, T.; Shibayama, T.; Nakagawa, A.; Iwamoto, A.; Yabe, Z. Structure-Activity Relationship of HIV-1 Protease Inhibitors Containing AHPBA. Part III: Modification of P2 Site. Bioorg. Med. Chem., 1998, 6, 595-604.
-
(1998)
Bioorg. Med. Chem.
, vol.6
, pp. 595-604
-
-
Takashiro, E.1
Watanabe, T.2
Nitta, T.3
Kasuya, A.4
Miyamoto, S.5
Ozawa, Y.6
Yagi, R.7
Nishigaki, T.8
Shibayama, T.9
Nakagawa, A.10
Iwamoto, A.11
Yabe, Z.12
-
84
-
-
0037137602
-
Metal-Dependent Inhibition of HIV-1 Integrase
-
Neamati, N.; Lin, Z.; Karki, R.G.; Orr, A.; Cowansage, K.; Strumberg, D.; Pais, G.C.G.; Voigt, J.H.; Nicklaus, M.C.; Winslow, H.E.; Zhao, H.; Turpin, J.A.; Yi, J.; Skalka, A.M.; Burke, T.R.; Pommier, Y. Metal-Dependent Inhibition of HIV-1 Integrase. J. Med. Chem., 2002, 45, 5661-5670.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 5661-5670
-
-
Neamati, N.1
Lin, Z.2
Karki, R.G.3
Orr, A.4
Cowansage, K.5
Strumberg, D.6
Pais, G.C.G.7
Voigt, J.H.8
Nicklaus, M.C.9
Winslow, H.E.10
Zhao, H.11
Turpin, J.A.12
Yi, J.13
Skalka, A.M.14
Burke, T.R.15
Pommier, Y.16
-
85
-
-
33745666317
-
Patented HIV-1 Integrase Inhibitors (1998-2005). Recent Pat
-
Cotelle, P. Patented HIV-1 Integrase Inhibitors (1998-2005). Recent Pat. Antiinfect. Drug Discov., 2006, 1, 1-15.
-
(2006)
Antiinfect. Drug Discov.
, vol.1
, pp. 1-15
-
-
Cotelle, P.1
-
86
-
-
12144254795
-
βDiketo Acid Pharmacophore Hypothesis. 1. Discovery of a Novel Class of HIV-1 Integrase Inhibitors
-
Dayam, R.; Sanchez, T.; Clement, O.; Shoemaker, R.; Sei, S.; Neamati, N. βDiketo Acid Pharmacophore Hypothesis. 1. Discovery of a Novel Class of HIV-1 Integrase Inhibitors. J. Med. Chem., 2005, 48, 111-120.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 111-120
-
-
Dayam, R.1
Sanchez, T.2
Clement, O.3
Shoemaker, R.4
Sei, S.5
Neamati, N.6
-
87
-
-
21144442096
-
Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2- benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid
-
Pfefferkorn, J.A.; Nugent, R.; Gross, R.J.; Greene, M.; Mitchell, M.A.; Reding, M.T.; Funk, L.A.; Anderson, R.; Wells, P.A.; Shelly, J.A.; Anstadt, R.; Finzel, B.C.; Harris, M.S.; Kilkuskie, R.E.; Kopta, L.A.; Schwende, F.J. Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2- benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid. Bioorg. Med. Chem. Lett., 2005, 15, 2812-2818.
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 2812-2818
-
-
Pfefferkorn, J.A.1
Nugent, R.2
Gross, R.J.3
Greene, M.4
Mitchell, M.A.5
Reding, M.T.6
Funk, L.A.7
Anderson, R.8
Wells, P.A.9
Shelly, J.A.10
Anstadt, R.11
Finzel, B.C.12
Harris, M.S.13
Kilkuskie, R.E.14
Kopta, L.A.15
Schwende, F.J.16
-
88
-
-
0030560967
-
Characterization of a Hemagglutinin- Specific Inhibitor of Influenza A Virus
-
Luo, G.X.; Colonno, R.; Krystal, M. Characterization of a Hemagglutinin- Specific Inhibitor of Influenza A Virus. Virology, 1996, 226, 66-76.
-
(1996)
Virology
, vol.226
, pp. 66-76
-
-
Luo, G.X.1
Colonno, R.2
Krystal, M.3
-
89
-
-
79952225829
-
Strategien für die Entwicklung neuartiger Grippemittel
-
Steinmetzer, T. Strategien für die Entwicklung neuartiger Grippemittel. Pharm. Unserer Zeit, 2011, 40, 160-168.
-
(2011)
Pharm. Unserer Zeit.
, vol.40
, pp. 160-168
-
-
Steinmetzer, T.1
-
90
-
-
0034618173
-
Salicylamide inhibitors of influenza virus fusion
-
Combrink, K.D.; Gulgeze, H.B.; Yu, KL.; Pearce, B.C.; Trehan, A.K.; Wei, J.M.; Deshpande, M.; Krystal, M.; Torri, A.; Luo, G.X.; Cianci, C.; Danetz, S.; Tiley, L.; Meanwell, N.A. Salicylamide inhibitors of influenza virus fusion. Bioorg. Med. Chem. Lett., 2000, 10, 1649-1652.
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 1649-1652
-
-
Combrink, K.D.1
Gulgeze, H.B.2
Yu, K.L.3
Pearce, B.C.4
Trehan, A.K.5
Wei, J.M.6
Deshpande, M.7
Krystal, M.8
Torri, A.9
Luo, G.X.10
Cianci, C.11
Danetz, S.12
Tiley, L.13
Meanwell, N.A.14
-
91
-
-
17944368500
-
An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology
-
Deshpande, M.S.; Wei, J.M.; Luo, G.X.; Cianci, C.; Danetz, S.; Torri, A.; Tiley, L.; Krystal, M.; Yu, K.L.; Huang, S.; Gao, Q.; Meanwell, N.A. An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology. Bioorg. Med. Chem. Lett., 2001, 11, 2393-2396.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 2393-2396
-
-
Deshpande, M.S.1
Wei, J.M.2
Luo, G.X.3
Cianci, C.4
Danetz, S.5
Torri, A.6
Tiley, L.7
Krystal, M.8
Yu, K.L.9
Huang, S.10
Gao, Q.11
Meanwell, N.A.12
-
92
-
-
0036888518
-
Structure- Activity Relationships for a Series of Thiobenzamide Influenza Fusion Inhibitors Derived from 1,3,3-Trimethyl-5-hydroxycyclohexylmethylamine
-
Yu, K.-L.; Torri, A.F.; Luo, G.X.; Cianci, C.; Grant-Young, K.; Danetz, S.; Tiley, L.; Krystal, M.; Meanwell, N.A. Structure- Activity Relationships for a Series of Thiobenzamide Influenza Fusion Inhibitors Derived from 1,3,3-Trimethyl-5-hydroxycyclohexylmethylamine. Bioorg. Med. Chem. Lett., 2002, 12, 3379-3382.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 3379-3382
-
-
Yu, K.-L.1
Torri, A.F.2
Luo, G.X.3
Cianci, C.4
Grant-Young, K.5
Danetz, S.6
Tiley, L.7
Krystal, M.8
Meanwell, N.A.9
-
93
-
-
37249016414
-
Anti-InfluenzaVirus Agents: Synthesis and Mode of Action
-
Lagoja, I.M.; De Clercq, E. Anti-InfluenzaVirus Agents: Synthesis and Mode of Action. Med. Res. Rev., 2008, 28, 1-38.
-
(2008)
Med. Res. Rev.
, vol.28
, pp. 1-38
-
-
Lagoja, I.M.1
de Clercq, E.2
-
94
-
-
0030894782
-
Molecular Mechanism Underlying the Action of a Novel Fusion Inhibitor of Influenza A Virus
-
Luo, G.X.; Torri, A.; Harte, W.E.; Danetz, S.; Cianci, C.; Tiley, L.; Day, S.; Mullaney, D.; Yu, K.L.; Ouellet, C.; Dextraze, P.; Meanwell, N.; Colonno, R.; Krystal, M. Molecular Mechanism Underlying the Action of a Novel Fusion Inhibitor of Influenza A Virus. J. Virol., 1997, 71, 4062-4070.
-
(1997)
J. Virol.
, vol.71
, pp. 4062-4070
-
-
Luo, G.X.1
Torri, A.2
Harte, W.E.3
Danetz, S.4
Cianci, C.5
Tiley, L.6
Day, S.7
Mullaney, D.8
Yu, K.L.9
Ouellet, C.10
Dextraze, P.11
Meanwell, N.12
Colonno, R.13
Krystal, M.14
-
95
-
-
68649122631
-
Emerging antiviral targets for influenza A virus
-
Krug, R.M.; Aramini, J.M. Emerging antiviral targets for influenza A virus. Trends Pharmacol. Sci., 2009, 30, 269-277.
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 269-277
-
-
Krug, R.M.1
Aramini, J.M.2
-
96
-
-
59649088815
-
Novel influenza virus NS1 antagonists block replication and restore innate immune function
-
Basu, D.; Walkiewicz, M.P.; Frieman, M.; Baric, R.S.; Auble, D.T.; Engel, D.A. Novel influenza virus NS1 antagonists block replication and restore innate immune function. J. Virol., 2009, 83, 1881-1891.
-
(2009)
J. Virol.
, vol.83
, pp. 1881-1891
-
-
Basu, D.1
Walkiewicz, M.P.2
Frieman, M.3
Baric, R.S.4
Auble, D.T.5
Engel, D.A.6
-
97
-
-
78649992830
-
TheHuman Rhinovirus: Human- Pathological Impact,Mechanisms of Antirhinoviral Agents, and Strategies forTheir Discovery
-
Rollinger, J.M.; Schmidtke, M. TheHuman Rhinovirus: Human- Pathological Impact,Mechanisms of Antirhinoviral Agents, and Strategies forTheir Discovery. Med. Res. Rev., 2010, 31, 42-92.
-
(2010)
Med. Res. Rev.
, vol.31
, pp. 42-92
-
-
Rollinger, J.M.1
Schmidtke, M.2
-
98
-
-
33646447042
-
-
Küçükgüzel, G.; Kocatepe, A.; De Clercq, E.; Şahin, F.; Güllüce, M. Synthesis and biological activity of 4-thiazolidinones, thiosemicarbazides derived from diflunisal hydrazide. Eur. J. Med. Chem., 2006, 41, 353-359.
-
(2006)
Eur. J. Med. Chem.
, vol.41
, pp. 353-359
-
-
Küçükgüzel, G.1
Kocatepe, A.2
de Clercq, E.3
Şahin, F.4
Güllüce, M.5
-
99
-
-
67649315549
-
Thiazolides: A New Class of Broad- Spectrum Antiviral Drugs Targeting Virus Maturation
-
Santoro, M.G.; Ciucci, A.; Gianferretti, P.; Belardo, G.; La Frazia, S.; Carta, S.; Rossignol, J.F. Thiazolides: A New Class of Broad- Spectrum Antiviral Drugs Targeting Virus Maturation. Antiviral Res., 2007, 74, A31.
-
(2007)
Antiviral Res
, vol.74
-
-
Santoro, M.G.1
Ciucci, A.2
Gianferretti, P.3
Belardo, G.4
la Frazia, S.5
Carta, S.6
Rossignol, J.F.7
-
100
-
-
67649307146
-
Thiazolides: A new class of antiviral drugs
-
Rossignol, J.F. Thiazolides: a new class of antiviral drugs. Exp. Opin. Drug Metabol. Toxicol., 2009, 5, 667-674.
-
(2009)
Exp. Opin. Drug Metabol. Toxicol.
, vol.5
, pp. 667-674
-
-
Rossignol, J.F.1
-
101
-
-
67650558979
-
Nitazoxanide for the treatment of chronic hepatitis C. New opportunities but new challenges
-
Mederacke, I.; Wedemeyer, H. Nitazoxanide for the treatment of chronic hepatitis C. New opportunities but new challenges? Ann. Hepatol., 2009, 8, 166-168.
-
(2009)
Ann. Hepatol.
, vol.8
, pp. 166-168
-
-
Mederacke, I.1
Wedemeyer, H.2
-
102
-
-
67651251216
-
Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides
-
Keeffe, E.B.; Rossignol, J.F. Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides. World J. Gastroenterology, 2009, 15, 1805-1808.
-
(2009)
World J. Gastroenterology.
, vol.15
, pp. 1805-1808
-
-
Keeffe, E.B.1
Rossignol, J.F.2
-
103
-
-
48449084880
-
Clinical trial: Randomized, double-blind, placebo-controlled study of nitazoxanide monotherapy for the treatment of patients with chronic hepatitis C genotype 4
-
Rossignol, J.F.; Kabil, S.M.; El-Gohary, Y.; Elfert, A.; Keeffe, E.B. Clinical trial: randomized, double-blind, placebo-controlled study of nitazoxanide monotherapy for the treatment of patients with chronic hepatitis C genotype 4. Aliment. Pharmacol. Ther., 2008, 28, 574-580.
-
(2008)
Aliment. Pharmacol. Ther.
, vol.28
, pp. 574-580
-
-
Rossignol, J.F.1
Kabil, S.M.2
El-Gohary, Y.3
Elfert, A.4
Keeffe, E.B.5
-
104
-
-
80052256645
-
Nitazoxanide is an Effective Antiviral Agent Against Both HBV and HCV replication in vitro
-
Korba, B.; Abigail, M.; Marc, A.; Rossignol, J.F. Nitazoxanide is an Effective Antiviral Agent Against Both HBV and HCV replication in vitro. Antiviral Res., 2007, 74, A40.
-
(2007)
Antiviral Res
, vol.74
-
-
Korba, B.1
Abigail, M.2
Marc, A.3
Rossignol, J.F.4
-
105
-
-
67650553098
-
Phase 2 randomized, doubleblind, placebo-controlled study of nitazoxanide plus peginterferon and ribavirin in HCV genotype 1 patients: Interim analysis shows increase in EVR
-
Bacon, B.; Shiffman, M.; Lim, J.; Berman, A.; Rustgi, V.; Keeffe, E. Phase 2 randomized, doubleblind, placebo-controlled study of nitazoxanide plus peginterferon and ribavirin in HCV genotype 1 patients: interim analysis shows increase in EVR. J. Hepatol., 2009, 50, S381.
-
(2009)
J. Hepatol.
, vol.50
-
-
Bacon, B.1
Shiffman, M.2
Lim, J.3
Berman, A.4
Rustgi, V.5
Keeffe, E.6
-
106
-
-
67650559106
-
Phase 2 randomized, double- blind, placebo-controlled study of nitazoxanide with peginterferon alfa-2a and ribavirin in nonresponders (NR) with chronic HCV genotype 1: Week 28 interim analysis
-
Shiffman, M.; Ahmed, A.; Jacobson, I. Phase 2 randomized, double- blind, placebo-controlled study of nitazoxanide with peginterferon alfa-2a and ribavirin in nonresponders (NR) with chronic HCV genotype 1: week 28 interim analysis. J. Hepatol., 2009, 50, S385-S386.
-
(2009)
J. Hepatol.
, vol.50
, pp. 385-386
-
-
Shiffman, M.1
Ahmed, A.2
Jacobson, I.3
-
107
-
-
55649090726
-
Evaluation of a 4 week lead-in phase with nitazoxanide (NTZ) prior to peginterferon (peginf) plus NTZ for treatment of chronic hepatitis C: Final report
-
Rossignol, J.F.; Elfert, A.; Keeffe, E.B. Evaluation of a 4 week lead-in phase with nitazoxanide (NTZ) prior to peginterferon (peginf) plus NTZ for treatment of chronic hepatitis C: final report. Hepatology, 2008, 48, 1132-1133.
-
(2008)
Hepatology
, vol.48
, pp. 1132-1133
-
-
Rossignol, J.F.1
Elfert, A.2
Keeffe, E.B.3
-
108
-
-
33750476857
-
Nitazoxanide in treating chronic hepatitis C: In vitro activity and a clinical case series
-
Rossignol, J.F.; Korba, B.E.; Kabil, S.M. Nitazoxanide in treating chronic hepatitis C: in vitro activity and a clinical case series. Gastroenterology, 2006, 130, A841.
-
(2006)
Gastroenterology
, vol.130
-
-
Rossignol, J.F.1
Korba, B.E.2
Kabil, S.M.3
-
109
-
-
60449108708
-
Improved Virologic Response in Chronic Hepatitis C Genotype 4 Treated With Nitazoxanide, Peginterferon, and Ribavirin
-
Rossignol, J.F.; Elfert, A.; El-Gohary, Y.; Keeffe, E.B. Improved Virologic Response in Chronic Hepatitis C Genotype 4 Treated With Nitazoxanide, Peginterferon, and Ribavirin. Gastroenterology, 2009, 136, 856-862.
-
(2009)
Gastroenterology
, vol.136
, pp. 856-862
-
-
Rossignol, J.F.1
Elfert, A.2
El-Gohary, Y.3
Keeffe, E.B.4
-
110
-
-
55449122030
-
Thiazolides: A new class of drugs for the treatment of chronic hepatitis B and C
-
Rossignol. J.F.; Keeffe, E.B. Thiazolides: a new class of drugs for the treatment of chronic hepatitis B and C. Future Microbiol., 2008, 3, 539-545.
-
(2008)
Future Microbiol
, vol.3
, pp. 539-545
-
-
Rossignol, J.F.1
Keeffe, E.B.2
-
111
-
-
37449014458
-
Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication
-
Korba, B.E.; Montero, A.B.; Farrar, K.; Gaye, K.; Mukerjee, S.; Ayers, M.S.; Rossignol, J.F. Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication. Antiviral Res., 2008, 77, 56-63.
-
(2008)
Antiviral Res
, vol.77
, pp. 56-63
-
-
Korba, B.E.1
Montero, A.B.2
Farrar, K.3
Gaye, K.4
Mukerjee, S.5
Ayers, M.S.6
Rossignol, J.F.7
-
112
-
-
70350125916
-
The Anti-Hepatitis C Agent Nitazoxanide Induces Phosphorylation of Eukaryotic Initiation Factor 2 alpha Via Protein Kinase Activated by Double-Stranded RNA Activation
-
Elazar, M.; Liu, M.; McKenna, S.A.; Liu, P.; Gehring, E.A.; Puglisi, J.D.; Rossignol, J.F.; Glenn, J.S. The Anti-Hepatitis C Agent Nitazoxanide Induces Phosphorylation of Eukaryotic Initiation Factor 2 alpha Via Protein Kinase Activated by Double-Stranded RNA Activation. Gastroenterology, 2009, 137, 1827-1835.
-
(2009)
Gastroenterology
, vol.137
, pp. 1827-1835
-
-
Elazar, M.1
Liu, M.2
McKenna, S.A.3
Liu, P.4
Gehring, E.A.5
Puglisi, J.D.6
Rossignol, J.F.7
Glenn, J.S.8
-
113
-
-
80052196548
-
A Role for Nitazoxanide in Combination with STAT-C Agents for Inhibition of HCV Replication and the Potential for the Prevention of Viral Resistance
-
Korba, B.; Glenn, J.; Elazar, M.; Rossignol, J.F. A Role for Nitazoxanide in Combination with STAT-C Agents for Inhibition of HCV Replication and the Potential for the Prevention of Viral Resistance. Antiviral Res., 2009, 82, A20.
-
(2009)
Antiviral Res
, vol.82
-
-
Korba, B.1
Glenn, J.2
Elazar, M.3
Rossignol, J.F.4
-
114
-
-
55849149779
-
Potential for Hepatitis C Virus Resistance to Nitazoxanide or Tizoxanide
-
Korba, B.E.; Elazar, M.; Lui, P.; Rossignol, J.F.; Glenn, J.S. Potential for Hepatitis C Virus Resistance to Nitazoxanide or Tizoxanide. Antimicrob. Agents Chemother., 2008, 52, 4069-4071.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 4069-4071
-
-
Korba, B.E.1
Elazar, M.2
Lui, P.3
Rossignol, J.F.4
Glenn, J.S.5
-
115
-
-
67349220665
-
Nitazoxanide vs. probiotics for the treatment of acute rotavirus diarrhea in children: A randomized, single-blind, controlled trial in Bolivian children
-
Teran, C.G.; Teran-Escalera, C.N.; Villarroel, P. Nitazoxanide vs. probiotics for the treatment of acute rotavirus diarrhea in children: a randomized, single-blind, controlled trial in Bolivian children. Int. J. Infect. Dis., 2009, 13, 518-523.
-
(2009)
Int. J. Infect. Dis.
, vol.13
, pp. 518-523
-
-
Teran, C.G.1
Teran-Escalera, C.N.2
Villarroel, P.3
-
116
-
-
33750461660
-
Nitazoxanide in the treatment of viral gastroenteritis: A randomized double-blind placebo-controlled clinical trial
-
Rossignol, J.F.; El-Gohary, Y.M. Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial. Aliment. Pharmacol. Ther., 2006, 24, 1423-1430.
-
(2006)
Aliment. Pharmacol. Ther.
, vol.24
, pp. 1423-1430
-
-
Rossignol, J.F.1
El-Gohary, Y.M.2
-
117
-
-
33745590112
-
Effect of nitazoxanide for treatment of severe rotavirus diarrhoea: Randomised double-blind placebo-controlled trial
-
Rossignol, J.F.; Abu-Zekry, M.; Hussein, A.; Santoro, M.G. Effect of nitazoxanide for treatment of severe rotavirus diarrhoea: randomised double-blind placebo-controlled trial. Lancet, 2006, 368, 124-129.
-
(2006)
Lancet
, vol.368
, pp. 124-129
-
-
Rossignol, J.F.1
Abu-Zekry, M.2
Hussein, A.3
Santoro, M.G.4
-
118
-
-
70350365369
-
Thiazolides, a New Class of Anti-influenza Molecules Targeting Viral Hemagglutinin at the Post-translational Level
-
Rossignol, J.F.; La Frazia, S.; Chiappa, L.; Ciucci, A.; Santoro, M.G. Thiazolides, a New Class of Anti-influenza Molecules Targeting Viral Hemagglutinin at the Post-translational Level. J. Biol. Chem., 2009, 284, 29798-29808.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 29798-29808
-
-
Rossignol, J.F.1
la Frazia, S.2
Chiappa, L.3
Ciucci, A.4
Santoro, M.G.5
-
119
-
-
0036498338
-
Treatment of intestinal parasitic infections: A review of nitazoxanide
-
Gilles, H.M.; Hoffman, P.S. Treatment of intestinal parasitic infections: a review of nitazoxanide. Trends Parasitol., 2002, 18, 95-97.
-
(2002)
Trends Parasitol
, vol.18
, pp. 95-97
-
-
Gilles, H.M.1
Hoffman, P.S.2
-
120
-
-
34548345811
-
Nitazoxanide. A Review of its Use in the Treatment of Gastrointestinal Infections
-
Anderson, V.R.; Curran, M.P. Nitazoxanide. A Review of its Use in the Treatment of Gastrointestinal Infections. Drugs, 2007, 67, 1947-1967.
-
(2007)
Drugs
, vol.67
, pp. 1947-1967
-
-
Anderson, V.R.1
Curran, M.P.2
-
121
-
-
33847660062
-
Antiparasitic Drug Nitazoxanide Inhibits the Pyruvate Oxidoreductases of Helicobacter pylori, Selected Anaerobic Bacteria and Parasites, and Campylobacter jejuni
-
Hoffman, P.S.; Sisson, G.; Croxen, M.A.; Welch, K.; Harman, W.D.; Cremades, N.; Morash, M.G. Antiparasitic Drug Nitazoxanide Inhibits the Pyruvate Oxidoreductases of Helicobacter pylori, Selected Anaerobic Bacteria and Parasites, and Campylobacter jejuni. Antimicrob. Agents Chemother., 2007, 51, 868-876.
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 868-876
-
-
Hoffman, P.S.1
Sisson, G.2
Croxen, M.A.3
Welch, K.4
Harman, W.D.5
Cremades, N.6
Morash, M.G.7
-
122
-
-
16844372587
-
Nitazoxanide: A New Thiazolide Antiparasitic Agent
-
Fox, L.M.; Saravolatz, L.D. Nitazoxanide: A New Thiazolide Antiparasitic Agent. Clin. Infect. Dis., 2005, 40, 1173-1180.
-
(2005)
Clin. Infect. Dis.
, vol.40
, pp. 1173-1180
-
-
Fox, L.M.1
Saravolatz, L.D.2
-
123
-
-
77950316746
-
Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes
-
Stadelmann, B.; Scholl, S.; Muller, J.; Hemphill, A. Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes. J. Antimicrob. Chemother., 2010, 65, 512-519.
-
(2010)
J. Antimicrob. Chemother.
, vol.65
, pp. 512-519
-
-
Stadelmann, B.1
Scholl, S.2
Muller, J.3
Hemphill, A.4
-
124
-
-
0036156713
-
In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis
-
Adagu, I.S.; Nolder, D.; Warhurst, D, Rossignol, J.F. In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis. J. Antimicrob. Chemother., 2006, 50, 103-111.
-
(2006)
J. Antimicrob. Chemother.
, vol.50
, pp. 103-111
-
-
Adagu, I.S.1
Nolder, D.2
Warhurst, D.3
Rossignol, J.F.4
-
125
-
-
0035984782
-
Enzymes Associated with Reductive Activation and Action of Nitazoxanide, Nitrofurans, and Metronidazole in Helicobacter pylori
-
Sisson, G.; Goodwin, A.; Raudonikiene, A.; Hughes, N.J.; Mukhopadhyay, A.K.; Berg, D.E.; Hoffman, P.S. Enzymes Associated with Reductive Activation and Action of Nitazoxanide, Nitrofurans, and Metronidazole in Helicobacter pylori. Antimicrob. Agents Chemother., 2002, 46, 2116-2123.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 2116-2123
-
-
Sisson, G.1
Goodwin, A.2
Raudonikiene, A.3
Hughes, N.J.4
Mukhopadhyay, A.K.5
Berg, D.E.6
Hoffman, P.S.7
-
126
-
-
77954218167
-
Biological Activity of Modified and Exchanged 2-Amino-5-Nitrothiazole Amide Analogues of Nitazoxanide
-
Ballard, T.E., Wang, X., Olekhnovich, I., Koerner, T., Seymour, C., Hoffman, P.S., Macdonald, T.L. Biological Activity of Modified and Exchanged 2-Amino-5-Nitrothiazole Amide Analogues of Nitazoxanide, Bioorg. Med. Chem. Lett., 2010, 20, 3537-3539.
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 3537-3539
-
-
Ballard, T.E.1
Wang, X.2
Olekhnovich, I.3
Koerner, T.4
Seymour, C.5
Hoffman, P.S.6
Macdonald, T.L.7
-
127
-
-
33644653117
-
Activities of Tizoxanide and Nitazoxanide Compared to Those of Five Other Thiazolides and Three Other Agents against Anaerobic Species
-
Pankuch, G.A.; Appelbaum, P.C. Activities of Tizoxanide and Nitazoxanide Compared to Those of Five Other Thiazolides and Three Other Agents against Anaerobic Species. Antimicrob. Agents Chemother., 2006, 50, 1112-1117.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 1112-1117
-
-
Pankuch, G.A.1
Appelbaum, P.C.2
-
128
-
-
55649111521
-
Nitazoxanide in the Treatment of Clostridium difficile Disease
-
Musher, D.M; Logan, N.D.; Bressler, A.M.; Johnson, D.P.; Rossignol, J.F. Nitazoxanide in the Treatment of Clostridium difficile Disease. Gastroenterology, 2008, 134, A-669.
-
(2008)
Gastroenterology
, vol.134
-
-
Musher, D.M.1
Logan, N.D.2
Bressler, A.M.3
Johnson, D.P.4
Rossignol, J.F.5
-
129
-
-
33746626011
-
Nitazoxanide for the treatment of Clostridium difficile colitis
-
Musher, D.M.; Logan, N.; Hamill, R.J.; DuPont, H.L.; Lentnek, A.; Gupta, A.; Rossignol, J.F. Nitazoxanide for the treatment of Clostridium difficile colitis. Clin. Infect. Dis., 2006, 43, 421-427.
-
(2006)
Clin. Infect. Dis.
, vol.43
, pp. 421-427
-
-
Musher, D.M.1
Logan, N.2
Hamill, R.J.3
Dupont, H.L.4
Lentnek, A.5
Gupta, A.6
Rossignol, J.F.7
-
130
-
-
34250015914
-
Clostridium difficile colitis that fails conventional metronidazole therapy: Response to nitazoxanide
-
Musher, D.M.; Logan, N.; Mehendiratta, V.; Melgarejo, N.A.; Garud, S.; Hamill, R.J. Clostridium difficile colitis that fails conventional metronidazole therapy: response to nitazoxanide. J. Antimicrob. Chemother., 2007, 59, 705-710.
-
(2007)
J. Antimicrob. Chemother.
, vol.59
, pp. 705-710
-
-
Musher, D.M.1
Logan, N.2
Mehendiratta, V.3
Melgarejo, N.A.4
Garud, S.5
Hamill, R.J.6
-
131
-
-
80052199164
-
Nitazoxanide and tizoxanide inhibit EHV-1 and influenza type A virus replication in vitro
-
Callan, R.J.; Ashton, L.V.; Goehring, L.S. Nitazoxanide and tizoxanide inhibit EHV-1 and influenza type A virus replication in vitro. J. Vet. Intern. Med., 2008, 22, 738-738.
-
(2008)
J. Vet. Intern. Med.
, vol.22
, pp. 738
-
-
Callan, R.J.1
Ashton, L.V.2
Goehring, L.S.3
-
132
-
-
80052257498
-
Treatment of healthy Gardia spp. positive dogs with fenbendazole or nitazoxanide
-
Lappin, M.R.; Clark, M.; Scorza A.V. Treatment of healthy Gardia spp. positive dogs with fenbendazole or nitazoxanide. J. Vet. Intern. Med., 2008, 22, 778-778.
-
(2008)
J. Vet. Intern. Med.
, vol.22
, pp. 778
-
-
Lappin, M.R.1
Clark, M.2
Scorza, A.V.3
-
133
-
-
80052209424
-
Infectious agent prevalence rates in dogs with diarrhea and response to administration of fenbendazole or nitazoxanide
-
Lappin, M.R.; Spindel, M.; Riggenbach, L. Infectious agent prevalence rates in dogs with diarrhea and response to administration of fenbendazole or nitazoxanide. J. Vet. Intern. Med., 2008, 22, 779.
-
(2008)
J. Vet. Intern. Med.
, vol.22
, pp. 779
-
-
Lappin, M.R.1
Spindel, M.2
Riggenbach, L.3
-
134
-
-
33646096961
-
Equine Protozoal Myeloencephalitis: Treatment, Prognosis, and Prevention
-
MacKay, R.J. Equine Protozoal Myeloencephalitis: Treatment, Prognosis, and Prevention. Clin. Techniques Equine Pract., 2006, 5, 9-16.
-
(2006)
Clin. Techniques Equine Pract.
, vol.5
, pp. 9-16
-
-
Mackay, R.J.1
-
135
-
-
24144477935
-
In vitro Efficacies of Nitazoxanide and Other Thiazolides against Neospora caninum Tachyzoites Reveal Antiparasitic Activity Independent of the Nitro Group
-
M.; Stettler, R.; Moores, S.L.; Pidathala, C.; Muller, N.; Stachulski, A.; Berry, N.G.; Rossignol, J.F.; Hemphill, A. In vitro Efficacies of Nitazoxanide and Other Thiazolides against Neospora caninum Tachyzoites Reveal Antiparasitic Activity Independent of the Nitro Group. Antimicrob. Agents Chemother., 2005, 49, 3715-3723.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 3715-3723
-
-
-
136
-
-
33745623628
-
Nitazoxanide for rotavirus diarrhoea?
-
Lanata, C.F.; Franco, M. Nitazoxanide for rotavirus diarrhoea? Lancet, 2006, 368, 100-101.
-
(2006)
Lancet
, vol.368
, pp. 100-101
-
-
Lanata, C.F.1
Franco, M.2
-
137
-
-
60449113775
-
Nitazoxanide: Beyond Parasites toward a Novel Agent for Hepatitis C
-
Darling, J.M.; Fried, M.W. Nitazoxanide: Beyond Parasites toward a Novel Agent for Hepatitis C. Gastroenterology, 2009, 136, 760-763.
-
(2009)
Gastroenterology
, vol.136
, pp. 760-763
-
-
Darling, J.M.1
Fried, M.W.2
-
138
-
-
78651093820
-
Nitazoxanide use in Rota Viral Diarrhea. Cure or Controversy?
-
Babu, T.A.; Venkatesh, C. Nitazoxanide use in Rota Viral Diarrhea. Cure or Controversy? Indian J. Pediatr., 2010, 77, 1450.
-
(2010)
Indian J. Pediatr
, vol.77
, pp. 1450
-
-
Babu, T.A.1
Venkatesh, C.2
|