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Volumn 11, Issue 11, 2011, Pages 956-967

Antiviral activity of substituted salicylanilides - a review

Author keywords

Antiviral activity; Antiviral therapy; Nitazoxanide; Salicylamides; Salicylanilides

Indexed keywords

2 [[(2 PHENOXYETHOXY)CARBONOTHIOYL)(PHENYL]CARBAMOYL]PHENYL ACETATE; 2 HYDROXY 3,5 DIIODO N (4-PHENYLAMINO)PHENYL BENZAMIDE; 2 HYDROXY 4 (3 (2 HYDROXY 3,5 DINITROBENZAMIDO)PHENYL) 4 OXOBUT 2 ENOIC ACID; 3 [[3 (2,4 DIMETHYLPHENYLCARBOMOYL) 2 HYDROXYNAPHTHALEN 1 YL]DIAZENYL] 4 HYDROXYBENZENESULFONIC ACID; 3 TERT BUTYL 5 [2,4 DIOXOTETRAHYDROPYRIMIDINE 1(2H) YL) 2 HYDROXY N (4 (METHYLSULFONAMIDO)PHENYL]BENZAMIDE; ANTIPARASITIC AGENT; ANTIVIRUS AGENT; INTEGRASE INHIBITOR; N (4 SULFAMOYLPHENYL)BENZAMIDE; N [4 [3 (4 ACETAMIDOPHENYL)THIOUREIDO] 2 CHLOROPHENYL] 1 HYDROXY 2 NAPHTAMIDE; N [4 [3 (5 CHLORO 2,4 DIMETHOXYPHENYL) THIOUREIDO]PHENYL0 2 HYDROXYBENZAMIDE; NICLOSAMIDE; NITAZOXANIDE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PROTEINASE; RNA POLYMERASE; SALICYLANILIDE DERIVATIVE; TIZOXANIDE; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS DNA;

EID: 80052248027     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/138955711797068382     Document Type: Review
Times cited : (39)

References (138)
  • 1
    • 8744310788 scopus 로고    scopus 로고
    • Salicylanilidy - stále aktuální skupina s potenciální antibakteriální aktivitou
    • Vinšová, J.; Imramovský, A. Salicylanilidy - stále aktuální skupina s potenciální antibakteriální aktivitou. Cesk. Slov. Farm., 2004, 53, 294-299.
    • (2004) Cesk. Slov. Farm. , vol.53 , pp. 294-299
    • Vinšová, J.1    Imramovský, A.2
  • 2
    • 0015233783 scopus 로고
    • Mechanism of Action of Uncouplers of Oxidative Phosphorylation
    • Wilson, D.F.; Ting, H.P.; Koppelman, M.S. Mechanism of Action of Uncouplers of Oxidative Phosphorylation. Biochemistry, 1971, 10, 2897-2902.
    • (1971) Biochemistry , vol.10 , pp. 2897-2902
    • Wilson, D.F.1    Ting, H.P.2    Koppelman, M.S.3
  • 3
    • 0024269714 scopus 로고
    • Structural requirements of salicylanilides for uncoupling activity in mitochondria: Quantitative analysis of structureuncoupling relationships
    • Terada, H.; Goto, S.; Yamamoto, K.; Takeuchi, I.; Hamada, Y.; Miyake, K. Structural requirements of salicylanilides for uncoupling activity in mitochondria: quantitative analysis of structureuncoupling relationships. Biochim. Biophys. Acta, 1988, 936, 504-512.
    • (1988) Biochim. Biophys. Acta. , vol.936 , pp. 504-512
    • Terada, H.1    Goto, S.2    Yamamoto, K.3    Takeuchi, I.4    Hamada, Y.5    Miyake, K.6
  • 4
    • 0037726805 scopus 로고    scopus 로고
    • Intrinsic and extrinsic uncoupling of oxidative phosphorylation
    • Kadenbach, B. Intrinsic and extrinsic uncoupling of oxidative phosphorylation. Biochim. Biophys. Acta, 2003, 1604, 77-94.
    • (2003) Biochim. Biophys. Acta. , vol.1604 , pp. 77-94
    • Kadenbach, B.1
  • 7
  • 9
    • 1342310784 scopus 로고    scopus 로고
    • Regulation of TNF-α and IFN-γ induced CXCL10 expression: Participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease
    • Hardaker, A.L.; Bacon, A.M.; Carlson, K.; Roshak, A.K.; Foley, J.J.; Schmidt, D.B.; Buckley, P.T.; Comegys, M.; Panettieri, R.A.; Sarau, H.M.; Belmonte, K.E. Regulation of TNF-α and IFN-γ induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease. FASEB J., 2003, 17, 191.
    • (2003) FASEB J , vol.17 , pp. 191
    • Hardaker, A.L.1    Bacon, A.M.2    Carlson, K.3    Roshak, A.K.4    Foley, J.J.5    Schmidt, D.B.6    Buckley, P.T.7    Comegys, M.8    Panettieri, R.A.9    Sarau, H.M.10    Belmonte, K.E.11
  • 10
    • 55949137433 scopus 로고    scopus 로고
    • Synthesis and anti-inflammatory-analgesic activity of 2́,4́-difluoro-3- (carbamoyl)biphenyl-4-yl benzoates
    • Zhong, G.X.; Chen, L.L.; Li, J.; Hu, W.X.; Qi, M.Y. Synthesis and anti-inflammatory-analgesic activity of 2́,4́-difluoro-3- (carbamoyl)biphenyl-4-yl benzoates. Chin. Chem. Lett., 2008, 19, 1419-1422.
    • (2008) Chin. Chem. Lett. , vol.19 , pp. 1419-1422
    • Zhong, G.X.1    Chen, L.L.2    Li, J.3    Hu, W.X.4    Qi, M.Y.5
  • 14
    • 9644259011 scopus 로고    scopus 로고
    • 4- Anilinoquinazolines with LavendustinA subunit as inhibitors of epidermal growth factor receptor tyrosine kinase: Syntheses, chemical and pharmacological properties
    • Albuschat, R.; Löwe, W.; Weber, M.; Luger, P.; Jendrossek, V. 4- Anilinoquinazolines with LavendustinA subunit as inhibitors of epidermal growth factor receptor tyrosine kinase: syntheses, chemical and pharmacological properties. Eur. J. Med. Chem., 2004, 39, 1001-1011.
    • (2004) Eur. J. Med. Chem. , vol.39 , pp. 1001-1011
    • Albuschat, R.1    Löwe, W.2    Weber, M.3    Luger, P.4    Jendrossek, V.5
  • 15
    • 1342279609 scopus 로고    scopus 로고
    • Salicylanilides as inhibitors of the protein tyrosine kinase epidermal growth factor receptor
    • Liechti, C.; Séquin, U.; Bold, G.; Furet, P.; Meyer, T.; Traxler, P. Salicylanilides as inhibitors of the protein tyrosine kinase epidermal growth factor receptor. Eur. J. Med. Chem., 2004, 39, 11-26.
    • (2004) Eur. J. Med. Chem. , vol.39 , pp. 11-26
    • Liechti, C.1    Séquin, U.2    Bold, G.3    Furet, P.4    Meyer, T.5    Traxler, P.6
  • 17
    • 32944462450 scopus 로고    scopus 로고
    • SUCI02 inhibits the erbB-2 tyrosine kinase receptor signaling pathway and arrests the cell cycle in G1 phase in breast cancer cells
    • Zhu, X.F.; Wang, J.S.; Cai, L.L.; Zeng, Y.X.; Yang, D. SUCI02 inhibits the erbB-2 tyrosine kinase receptor signaling pathway and arrests the cell cycle in G1 phase in breast cancer cells. Cancer Sci., 2006, 97, 84-89.
    • (2006) Cancer Sci , vol.97 , pp. 84-89
    • Zhu, X.F.1    Wang, J.S.2    Cai, L.L.3    Zeng, Y.X.4    Yang, D.5
  • 19
    • 0032833154 scopus 로고    scopus 로고
    • Antituberculosis activity of certain antifungal and anthelmintic drugs
    • Sun, Z.; Zhang, Y. Antituberculosis activity of certain antifungal and anthelmintic drugs. Tuber. Lung Dis., 1999, 79, 319-320.
    • (1999) Tuber. Lung Dis. , vol.79 , pp. 319-320
    • Sun, Z.1    Zhang, Y.2
  • 22
    • 65349142609 scopus 로고    scopus 로고
    • New Antituberculotics Originated from Salicylanilides with Promising In vitro Activity against Atypical Mycobacterial Strains
    • Imramovský, A.; Vinšová, J.; Férriz, J.M.; Doležal, R.; Jampílek, J.; Kaustová, J.; Kunc, F. New Antituberculotics Originated from Salicylanilides with Promising In vitro Activity against Atypical Mycobacterial Strains. Bioorg. Med. Chem., 2009, 17, 3572-3579.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 3572-3579
    • Imramovský, A.1    Vinšová, J.2    Férriz, J.M.3    Doležal, R.4    Jampílek, J.5    Kaustová, J.6    Kunc, F.7
  • 26
    • 78649327783 scopus 로고    scopus 로고
    • New amino acid esters of salicylanilides active against MDR-TB and other microbes
    • Krátký, M.; Vinšová, J.; Buchta, V.; Horvati, K.; Bösze, S.; Stolaříková, J. New amino acid esters of salicylanilides active against MDR-TB and other microbes. Eur. J. Med. Chem., 2010, 45, 6106-6113.
    • (2010) Eur. J. Med. Chem. , vol.45 , pp. 6106-6113
  • 28
    • 42149152602 scopus 로고    scopus 로고
    • The Antimicrobial Activity and Quantitative Structure - Biological Activity Relationships Evaluation of Some Novel 2- Hydroxybenzamide Derivatives
    • Ienacu, I.M.C.; Lupea, A.X.; Hadaruga, D.; Hadaruga, N.; Popescu, I.M. The Antimicrobial Activity and Quantitative Structure - Biological Activity Relationships Evaluation of Some Novel 2- Hydroxybenzamide Derivatives. Rev. Chim., 2008, 59, 247-250.
    • (2008) Rev. Chim. , vol.59 , pp. 247-250
    • Ienacu, I.M.C.1    Lupea, A.X.2    Hadaruga, D.3    Hadaruga, N.4    Popescu, I.M.5
  • 29
    • 70349256258 scopus 로고    scopus 로고
    • Synthesis and Antifungal Evaluation of Hydroxy-3- phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Their Thioanalogs
    • Skála, P.; Macháček, M.; Vejsová, M.; Kubicová, L.; Kuneš. J.; Waisser, K. Synthesis and Antifungal Evaluation of Hydroxy-3- phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Their Thioanalogs. J. Heterocyclic Chem., 2009, 46, 873-880.
    • (2009) J. Heterocyclic Chem. , vol.46 , pp. 873-880
    • Skála, P.1    Macháček, M.2    Vejsová, M.3    Kubicová, L.4    Kuneš, J.5    Waisser, K.6
  • 32
    • 0032807458 scopus 로고    scopus 로고
    • Multiple Mechanisms of Action for Inhibitors of Histidine Protein Kinases from Bacterial Two-Component Systems
    • Hilliard, J.J.; Goldschmidt, R.M.; Licata, L.; Baum, E.Z.; Bush, K. Multiple Mechanisms of Action for Inhibitors of Histidine Protein Kinases from Bacterial Two-Component Systems. Antimicrob. Agents Chemother., 1999, 43, 1693-1699.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 1693-1699
    • Hilliard, J.J.1    Goldschmidt, R.M.2    Licata, L.3    Baum, E.Z.4    Bush, K.5
  • 33
    • 22844455188 scopus 로고    scopus 로고
    • Relationships between the Chemical Structure of Substances and their Antimycobacterial Activity Against Atypical Strains. Part 18. 3-Phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Isosteric 3-Phenylquinazoline-2,4-(1H,3H)-diones
    • Waisser, K.; Macháček, M.; Dostál, H.; Gregor, J.; Kubicová, L.; Klimešová, V.; Kuneš, J.; Palát, K.; Hladůvková, J.; Kaustová, J.; Molmann, U. Relationships between the Chemical Structure of Substances and their Antimycobacterial Activity Against Atypical Strains. Part 18. 3-Phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Isosteric 3-Phenylquinazoline-2,4-(1H,3H)-diones. Collect. Czech Chem. Commun., 1999, 24, 1902-1924.
    • (1999) Collect. Czech Chem. Commun. , vol.24 , pp. 1902-1924
    • Waisser, K.1    Macháček, M.2    Dostál, H.3    Gregor, J.4    Kubicová, L.5    Klimešová, V.6    Kuneš, J.7    Palát, K.8    Hladůvková, J.9    Kaustová, J.10    Molmann, U.11
  • 34
    • 27944489895 scopus 로고    scopus 로고
    • Synthesis of novel oxazolidinone derivatives for antibacterial investigation
    • Cui, Y.; Dang, Y.; Yang, Y.; Ji, R. Synthesis of novel oxazolidinone derivatives for antibacterial investigation. Curr. Sci., 2005, 89, 531-534.
    • (2005) Curr. Sci. , vol.89 , pp. 531-534
    • Cui, Y.1    Dang, Y.2    Yang, Y.3    Ji, R.4
  • 35
    • 33750468980 scopus 로고    scopus 로고
    • Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening
    • De La Fuente, R.; Sonawane, N.D.; Arumainayagam, D.; Verkman, A.S. Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening. Br. J. Pharmacol., 2006, 149, 551-559.
    • (2006) Br. J. Pharmacol. , vol.149 , pp. 551-559
    • de la Fuente, R.1    Sonawane, N.D.2    Arumainayagam, D.3    Verkman, A.S.4
  • 36
    • 37849049329 scopus 로고    scopus 로고
    • Design, Synthesis, and Multivariate Quantitative Structure-Activity Relationship of Salicylanilides - Potent Inhibitors of Type III Secretion in Yersinia
    • Dahlgren, M.K.; Kauppi, A.M.; Olsson, I.M.; Linusson, A.; Elofsson, M. Design, Synthesis, and Multivariate Quantitative Structure-Activity Relationship of Salicylanilides - Potent Inhibitors of Type III Secretion in Yersinia. J. Med. Chem., 2007, 50, 6177-6188.
    • (2007) J. Med. Chem. , vol.50 , pp. 6177-6188
    • Dahlgren, M.K.1    Kauppi, A.M.2    Olsson, I.M.3    Linusson, A.4    Elofsson, M.5
  • 37
    • 42149152602 scopus 로고    scopus 로고
    • The Antimicrobial Activity and Quantitative Structure - Biological Activity Relationships Evaluation of Some Novel 2- Hydroxybenzamide Derivatives
    • Ienacu, I.M.C.; Lupea, A.X.; Hadaruga, D.; Hadaruga, N.; Popescu, I.M. The Antimicrobial Activity and Quantitative Structure - Biological Activity Relationships Evaluation of Some Novel 2- Hydroxybenzamide Derivatives. Rev. Chim., 2008, 59, 247-250.
    • (2008) Rev. Chim. , vol.59 , pp. 247-250
    • Ienacu, I.M.C.1    Lupea, A.X.2    Hadaruga, D.3    Hadaruga, N.4    Popescu, I.M.5
  • 40
    • 0037824419 scopus 로고    scopus 로고
    • Photocontact dermatitis and chloracne: Two major occupational and environmental skin diseases induced by different actions of halogenated chemicals
    • Yamamoto, O.; Tokura, Y. Photocontact dermatitis and chloracne: two major occupational and environmental skin diseases induced by different actions of halogenated chemicals. J. Dermatol. Sci., 2003, 32, 85-94.
    • (2003) J. Dermatol. Sci. , vol.32 , pp. 85-94
    • Yamamoto, O.1    Tokura, Y.2
  • 41
    • 77949333203 scopus 로고    scopus 로고
    • A 20-year analysis of previous and emerging allergens that elicit photoallergic contact dermatitis
    • Victor, F.C.; Cohen, D.E.; Soter, N.A. A 20-year analysis of previous and emerging allergens that elicit photoallergic contact dermatitis. J. Am. Acad. Dermatol., 2010, 62, 605-610.
    • (2010) J. Am. Acad. Dermatol. , vol.62 , pp. 605-610
    • Victor, F.C.1    Cohen, D.E.2    Soter, N.A.3
  • 44
    • 0025941977 scopus 로고
    • Mutagenic activity of 2-chloro-4-nitroaniline and 5-chlorosalicylic acid in Salmonella typhimurium - 2 possible metabolites of niclosamide
    • Espinosa-Aguirre, J.J.; Reyes, R.E.; de Nava, C.C. Mutagenic activity of 2-chloro-4-nitroaniline and 5-chlorosalicylic acid in Salmonella typhimurium - 2 possible metabolites of niclosamide. Mut. Res., 1991, 264, 139-145.
    • (1991) Mut. Res. , vol.264 , pp. 139-145
    • Espinosa-Aguirre, J.J.1    Reyes, R.E.2    de Nava, C.C.3
  • 45
    • 0030586767 scopus 로고    scopus 로고
    • Comparative genotoxicity of six salicylic acid derivatives in bone marrow cells of mice
    • Girl, A.K.; Adhikari, N.; Khan, K.A. Comparative genotoxicity of six salicylic acid derivatives in bone marrow cells of mice. Mutat. Res., 1996, 370, 1-9.
    • (1996) Mutat. Res. , vol.370 , pp. 1-9
    • Girl, A.K.1    Adhikari, N.2    Khan, K.A.3
  • 46
    • 34248670871 scopus 로고    scopus 로고
    • Clastogenic Effects of the Fasciolicides Closantel and Nitroxynil on Mice Somatic and Germ Cells
    • Donya, S.M.; Hassan, E.E. Clastogenic Effects of the Fasciolicides Closantel and Nitroxynil on Mice Somatic and Germ Cells. Cytologia, 2007, 72, 29-36.
    • (2007) Cytologia , vol.72 , pp. 29-36
    • Donya, S.M.1    Hassan, E.E.2
  • 47
    • 0029739563 scopus 로고    scopus 로고
    • Structure-Based Design of Achiral, Nonpeptidic Hydroxybenzamide as a Novel P2/P2' Replacement for the Symmetry-Based HIV Protease Inhibitors
    • Randad, R.S.; Lubkowska, L.; Silva, A.M.; Guerin, D.M.A.; Gulnik, S.V.; Yu, B.; Erickson, J.W. Structure-Based Design of Achiral, Nonpeptidic Hydroxybenzamide as a Novel P2/P2' Replacement for the Symmetry-Based HIV Protease Inhibitors. Bioorg. Med. Chem., 1996, 4, 1471-1480.
    • (1996) Bioorg. Med. Chem. , vol.4 , pp. 1471-1480
    • Randad, R.S.1    Lubkowska, L.2    Silva, A.M.3    Guerin, D.M.A.4    Gulnik, S.V.5    Yu, B.6    Erickson, J.W.7
  • 48
    • 77957073597 scopus 로고    scopus 로고
    • Antiviral Chemotherapy
    • Keating, M.R. Antiviral Chemotherapy. Princip. Med. Biol., 1998, 9, 529-549.
    • (1998) Princip. Med. Biol. , vol.9 , pp. 529-549
    • Keating, M.R.1
  • 49
    • 12444289560 scopus 로고    scopus 로고
    • The road to new antiviral therapies
    • Jerome, K.R. The road to new antiviral therapies. Clin. Appl. Immun. Rev., 2005, 5, 65-76.
    • (2005) Clin. Appl. Immun. Rev. , vol.5 , pp. 65-76
    • Jerome, K.R.1
  • 50
    • 33747095403 scopus 로고    scopus 로고
    • Antiviral drug resistance
    • Richman, D.D. Antiviral drug resistance. Antiviral Res., 2006, 71, 117-121.
    • (2006) Antiviral Res , vol.71 , pp. 117-121
    • Richman, D.D.1
  • 51
    • 67949118684 scopus 로고    scopus 로고
    • A perspective on antiviral resistence
    • Griffiths, P.D. A perspective on antiviral resistence. J. Clin. Virol., 2009, 46, 3-8.
    • (2009) J. Clin. Virol. , vol.46 , pp. 3-8
    • Griffiths, P.D.1
  • 55
    • 2142657824 scopus 로고    scopus 로고
    • Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs
    • Zhang, X.W.; Yap, Y.L. Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs. Bioorg. Med. Chem., 2004, 12, 2517-2521.
    • (2004) Bioorg. Med. Chem. , vol.12 , pp. 2517-2521
    • Zhang, X.W.1    Yap, Y.L.2
  • 60
    • 62949189676 scopus 로고    scopus 로고
    • Amide-containing diketoacids as HIV-1 integrase inhibitors: Synthesis, structure-activity relationship analysis, and biological activity
    • Li, H.C.; Wang, C.; Sanchez, T.; Tan, Y.; Jiang, C.; Neamati, N.; Zhao, G. Amide-containing diketoacids as HIV-1 integrase inhibitors: Synthesis, structure-activity relationship analysis, and biological activity. Bioorg. Med. Chem., 2009, 17, 2913-2919.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 2913-2919
    • Li, H.C.1    Wang, C.2    Sanchez, T.3    Tan, Y.4    Jiang, C.5    Neamati, N.6    Zhao, G.7
  • 63
    • 34547108566 scopus 로고    scopus 로고
    • New Developments in Diketo-Containing Inhibitors of HIV-1 Integrase
    • Zhao, G.; Wang, C.; Liu, C.; Lou, H. New Developments in Diketo-Containing Inhibitors of HIV-1 Integrase. Mini-Rev. Med. Chem., 2007, 7, 707-725.
    • (2007) Mini-Rev. Med. Chem. , vol.7 , pp. 707-725
    • Zhao, G.1    Wang, C.2    Liu, C.3    Lou, H.4
  • 66
    • 0037468526 scopus 로고    scopus 로고
    • Design, Synthesis, SAR, and Molecular Modeling Studies of Acylthiocarbamates: A Novel Series of Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Structurally Related to Phenethylthiazolylthiourea Derivatives
    • Ranise, A.; Spallarossa, A.; Schenone, S.; Bruno, O.; Bondavalli, F.; Vargiu, L.; Marceddu, T.; Mura, M.; La Colla, P.; Pani, A. Design, Synthesis, SAR, and Molecular Modeling Studies of Acylthiocarbamates: A Novel Series of Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Structurally Related to Phenethylthiazolylthiourea Derivatives. J. Med. Chem., 2003, 46, 768-781.
    • (2003) J. Med. Chem. , vol.46 , pp. 768-781
    • Ranise, A.1    Spallarossa, A.2    Schenone, S.3    Bruno, O.4    Bondavalli, F.5    Vargiu, L.6    Marceddu, T.7    Mura, M.8    la Colla, P.9    Pani, A.10
  • 67
    • 0031047399 scopus 로고    scopus 로고
    • The Human Immunodeficiency Virus Type 1 (HIV-1) Nucleocapsid Protein Zinc Ejection Activity of Disulfide Benzamides and Benzisothiazolones: Correlation with Anti-HIV and Virucidal Activities
    • Tummino, P.J.; Harvey, P.J.; McQuade, T.; Domagala, J.; Gogliotti, R.; Sanchez, J.; Song, Y.; Hupe, D. The Human Immunodeficiency Virus Type 1 (HIV-1) Nucleocapsid Protein Zinc Ejection Activity of Disulfide Benzamides and Benzisothiazolones: Correlation with Anti-HIV and Virucidal Activities. Antimicrob. Agents Chemother., 1997, 41, 394-400.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 394-400
    • Tummino, P.J.1    Harvey, P.J.2    McQuade, T.3    Domagala, J.4    Gogliotti, R.5    Sanchez, J.6    Song, Y.7    Hupe, D.8
  • 68
    • 12144260229 scopus 로고    scopus 로고
    • Control of Hepatitis C: A Medicinal Chemistry Perspective
    • Gordon, C.P.; Keller, P.A. Control of Hepatitis C: A Medicinal Chemistry Perspective. J. Med. Chem., 2005, 48, 1-20.
    • (2005) J. Med. Chem. , vol.48 , pp. 1-20
    • Gordon, C.P.1    Keller, P.A.2
  • 70
    • 67650526658 scopus 로고    scopus 로고
    • Current and future treatment options for HCV
    • Kronenberger, B.; Zeuzem, S. Current and future treatment options for HCV. Ann. Hepatol., 2009, 8, 103-112.
    • (2009) Ann. Hepatol. , vol.8 , pp. 103-112
    • Kronenberger, B.1    Zeuzem, S.2
  • 71
    • 33846207539 scopus 로고    scopus 로고
    • Cell-Based, High-Throughput Screen for Small Molecule Regulators of Hepatitis C Virus Replication
    • Kim, S.S.; Peng, L.F.; Lin, W.; Choe, W.; Sakamoto, N.; Schreiber, S.L.; Chung, R.T. A Cell-Based, High-Throughput Screen for Small Molecule Regulators of Hepatitis C Virus Replication. Gastroenterology, 2007, 132, 311-320.
    • (2007) Gastroenterology , vol.132 , pp. 311-320
    • Kim, S.S.1    Peng, L.F.2    Lin, W.3    Choe, W.4    Sakamoto, N.5    Schreiber, S.L.6    Chung, R.T.A.7
  • 79
    • 0030855938 scopus 로고    scopus 로고
    • Design and discovery of HIV-1 integrase inhibitors
    • Neamati, N.; Sunder, S.; Pommier, Y. Design and discovery of HIV-1 integrase inhibitors. Drug Discov. Today, 1997, 2, 487-498.
    • (1997) Drug Discov. Today , vol.2 , pp. 487-498
    • Neamati, N.1    Sunder, S.2    Pommier, Y.3
  • 85
    • 33745666317 scopus 로고    scopus 로고
    • Patented HIV-1 Integrase Inhibitors (1998-2005). Recent Pat
    • Cotelle, P. Patented HIV-1 Integrase Inhibitors (1998-2005). Recent Pat. Antiinfect. Drug Discov., 2006, 1, 1-15.
    • (2006) Antiinfect. Drug Discov. , vol.1 , pp. 1-15
    • Cotelle, P.1
  • 86
    • 12144254795 scopus 로고    scopus 로고
    • βDiketo Acid Pharmacophore Hypothesis. 1. Discovery of a Novel Class of HIV-1 Integrase Inhibitors
    • Dayam, R.; Sanchez, T.; Clement, O.; Shoemaker, R.; Sei, S.; Neamati, N. βDiketo Acid Pharmacophore Hypothesis. 1. Discovery of a Novel Class of HIV-1 Integrase Inhibitors. J. Med. Chem., 2005, 48, 111-120.
    • (2005) J. Med. Chem. , vol.48 , pp. 111-120
    • Dayam, R.1    Sanchez, T.2    Clement, O.3    Shoemaker, R.4    Sei, S.5    Neamati, N.6
  • 88
    • 0030560967 scopus 로고    scopus 로고
    • Characterization of a Hemagglutinin- Specific Inhibitor of Influenza A Virus
    • Luo, G.X.; Colonno, R.; Krystal, M. Characterization of a Hemagglutinin- Specific Inhibitor of Influenza A Virus. Virology, 1996, 226, 66-76.
    • (1996) Virology , vol.226 , pp. 66-76
    • Luo, G.X.1    Colonno, R.2    Krystal, M.3
  • 89
    • 79952225829 scopus 로고    scopus 로고
    • Strategien für die Entwicklung neuartiger Grippemittel
    • Steinmetzer, T. Strategien für die Entwicklung neuartiger Grippemittel. Pharm. Unserer Zeit, 2011, 40, 160-168.
    • (2011) Pharm. Unserer Zeit. , vol.40 , pp. 160-168
    • Steinmetzer, T.1
  • 92
    • 0036888518 scopus 로고    scopus 로고
    • Structure- Activity Relationships for a Series of Thiobenzamide Influenza Fusion Inhibitors Derived from 1,3,3-Trimethyl-5-hydroxycyclohexylmethylamine
    • Yu, K.-L.; Torri, A.F.; Luo, G.X.; Cianci, C.; Grant-Young, K.; Danetz, S.; Tiley, L.; Krystal, M.; Meanwell, N.A. Structure- Activity Relationships for a Series of Thiobenzamide Influenza Fusion Inhibitors Derived from 1,3,3-Trimethyl-5-hydroxycyclohexylmethylamine. Bioorg. Med. Chem. Lett., 2002, 12, 3379-3382.
    • (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 3379-3382
    • Yu, K.-L.1    Torri, A.F.2    Luo, G.X.3    Cianci, C.4    Grant-Young, K.5    Danetz, S.6    Tiley, L.7    Krystal, M.8    Meanwell, N.A.9
  • 93
    • 37249016414 scopus 로고    scopus 로고
    • Anti-InfluenzaVirus Agents: Synthesis and Mode of Action
    • Lagoja, I.M.; De Clercq, E. Anti-InfluenzaVirus Agents: Synthesis and Mode of Action. Med. Res. Rev., 2008, 28, 1-38.
    • (2008) Med. Res. Rev. , vol.28 , pp. 1-38
    • Lagoja, I.M.1    de Clercq, E.2
  • 95
    • 68649122631 scopus 로고    scopus 로고
    • Emerging antiviral targets for influenza A virus
    • Krug, R.M.; Aramini, J.M. Emerging antiviral targets for influenza A virus. Trends Pharmacol. Sci., 2009, 30, 269-277.
    • (2009) Trends Pharmacol. Sci. , vol.30 , pp. 269-277
    • Krug, R.M.1    Aramini, J.M.2
  • 96
    • 59649088815 scopus 로고    scopus 로고
    • Novel influenza virus NS1 antagonists block replication and restore innate immune function
    • Basu, D.; Walkiewicz, M.P.; Frieman, M.; Baric, R.S.; Auble, D.T.; Engel, D.A. Novel influenza virus NS1 antagonists block replication and restore innate immune function. J. Virol., 2009, 83, 1881-1891.
    • (2009) J. Virol. , vol.83 , pp. 1881-1891
    • Basu, D.1    Walkiewicz, M.P.2    Frieman, M.3    Baric, R.S.4    Auble, D.T.5    Engel, D.A.6
  • 97
    • 78649992830 scopus 로고    scopus 로고
    • TheHuman Rhinovirus: Human- Pathological Impact,Mechanisms of Antirhinoviral Agents, and Strategies forTheir Discovery
    • Rollinger, J.M.; Schmidtke, M. TheHuman Rhinovirus: Human- Pathological Impact,Mechanisms of Antirhinoviral Agents, and Strategies forTheir Discovery. Med. Res. Rev., 2010, 31, 42-92.
    • (2010) Med. Res. Rev. , vol.31 , pp. 42-92
    • Rollinger, J.M.1    Schmidtke, M.2
  • 100
    • 67649307146 scopus 로고    scopus 로고
    • Thiazolides: A new class of antiviral drugs
    • Rossignol, J.F. Thiazolides: a new class of antiviral drugs. Exp. Opin. Drug Metabol. Toxicol., 2009, 5, 667-674.
    • (2009) Exp. Opin. Drug Metabol. Toxicol. , vol.5 , pp. 667-674
    • Rossignol, J.F.1
  • 101
    • 67650558979 scopus 로고    scopus 로고
    • Nitazoxanide for the treatment of chronic hepatitis C. New opportunities but new challenges
    • Mederacke, I.; Wedemeyer, H. Nitazoxanide for the treatment of chronic hepatitis C. New opportunities but new challenges? Ann. Hepatol., 2009, 8, 166-168.
    • (2009) Ann. Hepatol. , vol.8 , pp. 166-168
    • Mederacke, I.1    Wedemeyer, H.2
  • 102
    • 67651251216 scopus 로고    scopus 로고
    • Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides
    • Keeffe, E.B.; Rossignol, J.F. Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides. World J. Gastroenterology, 2009, 15, 1805-1808.
    • (2009) World J. Gastroenterology. , vol.15 , pp. 1805-1808
    • Keeffe, E.B.1    Rossignol, J.F.2
  • 103
    • 48449084880 scopus 로고    scopus 로고
    • Clinical trial: Randomized, double-blind, placebo-controlled study of nitazoxanide monotherapy for the treatment of patients with chronic hepatitis C genotype 4
    • Rossignol, J.F.; Kabil, S.M.; El-Gohary, Y.; Elfert, A.; Keeffe, E.B. Clinical trial: randomized, double-blind, placebo-controlled study of nitazoxanide monotherapy for the treatment of patients with chronic hepatitis C genotype 4. Aliment. Pharmacol. Ther., 2008, 28, 574-580.
    • (2008) Aliment. Pharmacol. Ther. , vol.28 , pp. 574-580
    • Rossignol, J.F.1    Kabil, S.M.2    El-Gohary, Y.3    Elfert, A.4    Keeffe, E.B.5
  • 104
    • 80052256645 scopus 로고    scopus 로고
    • Nitazoxanide is an Effective Antiviral Agent Against Both HBV and HCV replication in vitro
    • Korba, B.; Abigail, M.; Marc, A.; Rossignol, J.F. Nitazoxanide is an Effective Antiviral Agent Against Both HBV and HCV replication in vitro. Antiviral Res., 2007, 74, A40.
    • (2007) Antiviral Res , vol.74
    • Korba, B.1    Abigail, M.2    Marc, A.3    Rossignol, J.F.4
  • 105
    • 67650553098 scopus 로고    scopus 로고
    • Phase 2 randomized, doubleblind, placebo-controlled study of nitazoxanide plus peginterferon and ribavirin in HCV genotype 1 patients: Interim analysis shows increase in EVR
    • Bacon, B.; Shiffman, M.; Lim, J.; Berman, A.; Rustgi, V.; Keeffe, E. Phase 2 randomized, doubleblind, placebo-controlled study of nitazoxanide plus peginterferon and ribavirin in HCV genotype 1 patients: interim analysis shows increase in EVR. J. Hepatol., 2009, 50, S381.
    • (2009) J. Hepatol. , vol.50
    • Bacon, B.1    Shiffman, M.2    Lim, J.3    Berman, A.4    Rustgi, V.5    Keeffe, E.6
  • 106
    • 67650559106 scopus 로고    scopus 로고
    • Phase 2 randomized, double- blind, placebo-controlled study of nitazoxanide with peginterferon alfa-2a and ribavirin in nonresponders (NR) with chronic HCV genotype 1: Week 28 interim analysis
    • Shiffman, M.; Ahmed, A.; Jacobson, I. Phase 2 randomized, double- blind, placebo-controlled study of nitazoxanide with peginterferon alfa-2a and ribavirin in nonresponders (NR) with chronic HCV genotype 1: week 28 interim analysis. J. Hepatol., 2009, 50, S385-S386.
    • (2009) J. Hepatol. , vol.50 , pp. 385-386
    • Shiffman, M.1    Ahmed, A.2    Jacobson, I.3
  • 107
    • 55649090726 scopus 로고    scopus 로고
    • Evaluation of a 4 week lead-in phase with nitazoxanide (NTZ) prior to peginterferon (peginf) plus NTZ for treatment of chronic hepatitis C: Final report
    • Rossignol, J.F.; Elfert, A.; Keeffe, E.B. Evaluation of a 4 week lead-in phase with nitazoxanide (NTZ) prior to peginterferon (peginf) plus NTZ for treatment of chronic hepatitis C: final report. Hepatology, 2008, 48, 1132-1133.
    • (2008) Hepatology , vol.48 , pp. 1132-1133
    • Rossignol, J.F.1    Elfert, A.2    Keeffe, E.B.3
  • 108
    • 33750476857 scopus 로고    scopus 로고
    • Nitazoxanide in treating chronic hepatitis C: In vitro activity and a clinical case series
    • Rossignol, J.F.; Korba, B.E.; Kabil, S.M. Nitazoxanide in treating chronic hepatitis C: in vitro activity and a clinical case series. Gastroenterology, 2006, 130, A841.
    • (2006) Gastroenterology , vol.130
    • Rossignol, J.F.1    Korba, B.E.2    Kabil, S.M.3
  • 109
    • 60449108708 scopus 로고    scopus 로고
    • Improved Virologic Response in Chronic Hepatitis C Genotype 4 Treated With Nitazoxanide, Peginterferon, and Ribavirin
    • Rossignol, J.F.; Elfert, A.; El-Gohary, Y.; Keeffe, E.B. Improved Virologic Response in Chronic Hepatitis C Genotype 4 Treated With Nitazoxanide, Peginterferon, and Ribavirin. Gastroenterology, 2009, 136, 856-862.
    • (2009) Gastroenterology , vol.136 , pp. 856-862
    • Rossignol, J.F.1    Elfert, A.2    El-Gohary, Y.3    Keeffe, E.B.4
  • 110
    • 55449122030 scopus 로고    scopus 로고
    • Thiazolides: A new class of drugs for the treatment of chronic hepatitis B and C
    • Rossignol. J.F.; Keeffe, E.B. Thiazolides: a new class of drugs for the treatment of chronic hepatitis B and C. Future Microbiol., 2008, 3, 539-545.
    • (2008) Future Microbiol , vol.3 , pp. 539-545
    • Rossignol, J.F.1    Keeffe, E.B.2
  • 111
    • 37449014458 scopus 로고    scopus 로고
    • Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication
    • Korba, B.E.; Montero, A.B.; Farrar, K.; Gaye, K.; Mukerjee, S.; Ayers, M.S.; Rossignol, J.F. Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication. Antiviral Res., 2008, 77, 56-63.
    • (2008) Antiviral Res , vol.77 , pp. 56-63
    • Korba, B.E.1    Montero, A.B.2    Farrar, K.3    Gaye, K.4    Mukerjee, S.5    Ayers, M.S.6    Rossignol, J.F.7
  • 112
    • 70350125916 scopus 로고    scopus 로고
    • The Anti-Hepatitis C Agent Nitazoxanide Induces Phosphorylation of Eukaryotic Initiation Factor 2 alpha Via Protein Kinase Activated by Double-Stranded RNA Activation
    • Elazar, M.; Liu, M.; McKenna, S.A.; Liu, P.; Gehring, E.A.; Puglisi, J.D.; Rossignol, J.F.; Glenn, J.S. The Anti-Hepatitis C Agent Nitazoxanide Induces Phosphorylation of Eukaryotic Initiation Factor 2 alpha Via Protein Kinase Activated by Double-Stranded RNA Activation. Gastroenterology, 2009, 137, 1827-1835.
    • (2009) Gastroenterology , vol.137 , pp. 1827-1835
    • Elazar, M.1    Liu, M.2    McKenna, S.A.3    Liu, P.4    Gehring, E.A.5    Puglisi, J.D.6    Rossignol, J.F.7    Glenn, J.S.8
  • 113
    • 80052196548 scopus 로고    scopus 로고
    • A Role for Nitazoxanide in Combination with STAT-C Agents for Inhibition of HCV Replication and the Potential for the Prevention of Viral Resistance
    • Korba, B.; Glenn, J.; Elazar, M.; Rossignol, J.F. A Role for Nitazoxanide in Combination with STAT-C Agents for Inhibition of HCV Replication and the Potential for the Prevention of Viral Resistance. Antiviral Res., 2009, 82, A20.
    • (2009) Antiviral Res , vol.82
    • Korba, B.1    Glenn, J.2    Elazar, M.3    Rossignol, J.F.4
  • 115
    • 67349220665 scopus 로고    scopus 로고
    • Nitazoxanide vs. probiotics for the treatment of acute rotavirus diarrhea in children: A randomized, single-blind, controlled trial in Bolivian children
    • Teran, C.G.; Teran-Escalera, C.N.; Villarroel, P. Nitazoxanide vs. probiotics for the treatment of acute rotavirus diarrhea in children: a randomized, single-blind, controlled trial in Bolivian children. Int. J. Infect. Dis., 2009, 13, 518-523.
    • (2009) Int. J. Infect. Dis. , vol.13 , pp. 518-523
    • Teran, C.G.1    Teran-Escalera, C.N.2    Villarroel, P.3
  • 116
    • 33750461660 scopus 로고    scopus 로고
    • Nitazoxanide in the treatment of viral gastroenteritis: A randomized double-blind placebo-controlled clinical trial
    • Rossignol, J.F.; El-Gohary, Y.M. Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial. Aliment. Pharmacol. Ther., 2006, 24, 1423-1430.
    • (2006) Aliment. Pharmacol. Ther. , vol.24 , pp. 1423-1430
    • Rossignol, J.F.1    El-Gohary, Y.M.2
  • 117
    • 33745590112 scopus 로고    scopus 로고
    • Effect of nitazoxanide for treatment of severe rotavirus diarrhoea: Randomised double-blind placebo-controlled trial
    • Rossignol, J.F.; Abu-Zekry, M.; Hussein, A.; Santoro, M.G. Effect of nitazoxanide for treatment of severe rotavirus diarrhoea: randomised double-blind placebo-controlled trial. Lancet, 2006, 368, 124-129.
    • (2006) Lancet , vol.368 , pp. 124-129
    • Rossignol, J.F.1    Abu-Zekry, M.2    Hussein, A.3    Santoro, M.G.4
  • 118
    • 70350365369 scopus 로고    scopus 로고
    • Thiazolides, a New Class of Anti-influenza Molecules Targeting Viral Hemagglutinin at the Post-translational Level
    • Rossignol, J.F.; La Frazia, S.; Chiappa, L.; Ciucci, A.; Santoro, M.G. Thiazolides, a New Class of Anti-influenza Molecules Targeting Viral Hemagglutinin at the Post-translational Level. J. Biol. Chem., 2009, 284, 29798-29808.
    • (2009) J. Biol. Chem. , vol.284 , pp. 29798-29808
    • Rossignol, J.F.1    la Frazia, S.2    Chiappa, L.3    Ciucci, A.4    Santoro, M.G.5
  • 119
    • 0036498338 scopus 로고    scopus 로고
    • Treatment of intestinal parasitic infections: A review of nitazoxanide
    • Gilles, H.M.; Hoffman, P.S. Treatment of intestinal parasitic infections: a review of nitazoxanide. Trends Parasitol., 2002, 18, 95-97.
    • (2002) Trends Parasitol , vol.18 , pp. 95-97
    • Gilles, H.M.1    Hoffman, P.S.2
  • 120
    • 34548345811 scopus 로고    scopus 로고
    • Nitazoxanide. A Review of its Use in the Treatment of Gastrointestinal Infections
    • Anderson, V.R.; Curran, M.P. Nitazoxanide. A Review of its Use in the Treatment of Gastrointestinal Infections. Drugs, 2007, 67, 1947-1967.
    • (2007) Drugs , vol.67 , pp. 1947-1967
    • Anderson, V.R.1    Curran, M.P.2
  • 121
    • 33847660062 scopus 로고    scopus 로고
    • Antiparasitic Drug Nitazoxanide Inhibits the Pyruvate Oxidoreductases of Helicobacter pylori, Selected Anaerobic Bacteria and Parasites, and Campylobacter jejuni
    • Hoffman, P.S.; Sisson, G.; Croxen, M.A.; Welch, K.; Harman, W.D.; Cremades, N.; Morash, M.G. Antiparasitic Drug Nitazoxanide Inhibits the Pyruvate Oxidoreductases of Helicobacter pylori, Selected Anaerobic Bacteria and Parasites, and Campylobacter jejuni. Antimicrob. Agents Chemother., 2007, 51, 868-876.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 868-876
    • Hoffman, P.S.1    Sisson, G.2    Croxen, M.A.3    Welch, K.4    Harman, W.D.5    Cremades, N.6    Morash, M.G.7
  • 122
    • 16844372587 scopus 로고    scopus 로고
    • Nitazoxanide: A New Thiazolide Antiparasitic Agent
    • Fox, L.M.; Saravolatz, L.D. Nitazoxanide: A New Thiazolide Antiparasitic Agent. Clin. Infect. Dis., 2005, 40, 1173-1180.
    • (2005) Clin. Infect. Dis. , vol.40 , pp. 1173-1180
    • Fox, L.M.1    Saravolatz, L.D.2
  • 123
    • 77950316746 scopus 로고    scopus 로고
    • Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes
    • Stadelmann, B.; Scholl, S.; Muller, J.; Hemphill, A. Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes. J. Antimicrob. Chemother., 2010, 65, 512-519.
    • (2010) J. Antimicrob. Chemother. , vol.65 , pp. 512-519
    • Stadelmann, B.1    Scholl, S.2    Muller, J.3    Hemphill, A.4
  • 124
    • 0036156713 scopus 로고    scopus 로고
    • In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis
    • Adagu, I.S.; Nolder, D.; Warhurst, D, Rossignol, J.F. In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis. J. Antimicrob. Chemother., 2006, 50, 103-111.
    • (2006) J. Antimicrob. Chemother. , vol.50 , pp. 103-111
    • Adagu, I.S.1    Nolder, D.2    Warhurst, D.3    Rossignol, J.F.4
  • 127
    • 33644653117 scopus 로고    scopus 로고
    • Activities of Tizoxanide and Nitazoxanide Compared to Those of Five Other Thiazolides and Three Other Agents against Anaerobic Species
    • Pankuch, G.A.; Appelbaum, P.C. Activities of Tizoxanide and Nitazoxanide Compared to Those of Five Other Thiazolides and Three Other Agents against Anaerobic Species. Antimicrob. Agents Chemother., 2006, 50, 1112-1117.
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 1112-1117
    • Pankuch, G.A.1    Appelbaum, P.C.2
  • 131
    • 80052199164 scopus 로고    scopus 로고
    • Nitazoxanide and tizoxanide inhibit EHV-1 and influenza type A virus replication in vitro
    • Callan, R.J.; Ashton, L.V.; Goehring, L.S. Nitazoxanide and tizoxanide inhibit EHV-1 and influenza type A virus replication in vitro. J. Vet. Intern. Med., 2008, 22, 738-738.
    • (2008) J. Vet. Intern. Med. , vol.22 , pp. 738
    • Callan, R.J.1    Ashton, L.V.2    Goehring, L.S.3
  • 132
    • 80052257498 scopus 로고    scopus 로고
    • Treatment of healthy Gardia spp. positive dogs with fenbendazole or nitazoxanide
    • Lappin, M.R.; Clark, M.; Scorza A.V. Treatment of healthy Gardia spp. positive dogs with fenbendazole or nitazoxanide. J. Vet. Intern. Med., 2008, 22, 778-778.
    • (2008) J. Vet. Intern. Med. , vol.22 , pp. 778
    • Lappin, M.R.1    Clark, M.2    Scorza, A.V.3
  • 133
    • 80052209424 scopus 로고    scopus 로고
    • Infectious agent prevalence rates in dogs with diarrhea and response to administration of fenbendazole or nitazoxanide
    • Lappin, M.R.; Spindel, M.; Riggenbach, L. Infectious agent prevalence rates in dogs with diarrhea and response to administration of fenbendazole or nitazoxanide. J. Vet. Intern. Med., 2008, 22, 779.
    • (2008) J. Vet. Intern. Med. , vol.22 , pp. 779
    • Lappin, M.R.1    Spindel, M.2    Riggenbach, L.3
  • 134
    • 33646096961 scopus 로고    scopus 로고
    • Equine Protozoal Myeloencephalitis: Treatment, Prognosis, and Prevention
    • MacKay, R.J. Equine Protozoal Myeloencephalitis: Treatment, Prognosis, and Prevention. Clin. Techniques Equine Pract., 2006, 5, 9-16.
    • (2006) Clin. Techniques Equine Pract. , vol.5 , pp. 9-16
    • Mackay, R.J.1
  • 135
    • 24144477935 scopus 로고    scopus 로고
    • In vitro Efficacies of Nitazoxanide and Other Thiazolides against Neospora caninum Tachyzoites Reveal Antiparasitic Activity Independent of the Nitro Group
    • M.; Stettler, R.; Moores, S.L.; Pidathala, C.; Muller, N.; Stachulski, A.; Berry, N.G.; Rossignol, J.F.; Hemphill, A. In vitro Efficacies of Nitazoxanide and Other Thiazolides against Neospora caninum Tachyzoites Reveal Antiparasitic Activity Independent of the Nitro Group. Antimicrob. Agents Chemother., 2005, 49, 3715-3723.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 3715-3723
  • 136
    • 33745623628 scopus 로고    scopus 로고
    • Nitazoxanide for rotavirus diarrhoea?
    • Lanata, C.F.; Franco, M. Nitazoxanide for rotavirus diarrhoea? Lancet, 2006, 368, 100-101.
    • (2006) Lancet , vol.368 , pp. 100-101
    • Lanata, C.F.1    Franco, M.2
  • 137
    • 60449113775 scopus 로고    scopus 로고
    • Nitazoxanide: Beyond Parasites toward a Novel Agent for Hepatitis C
    • Darling, J.M.; Fried, M.W. Nitazoxanide: Beyond Parasites toward a Novel Agent for Hepatitis C. Gastroenterology, 2009, 136, 760-763.
    • (2009) Gastroenterology , vol.136 , pp. 760-763
    • Darling, J.M.1    Fried, M.W.2
  • 138
    • 78651093820 scopus 로고    scopus 로고
    • Nitazoxanide use in Rota Viral Diarrhea. Cure or Controversy?
    • Babu, T.A.; Venkatesh, C. Nitazoxanide use in Rota Viral Diarrhea. Cure or Controversy? Indian J. Pediatr., 2010, 77, 1450.
    • (2010) Indian J. Pediatr , vol.77 , pp. 1450
    • Babu, T.A.1    Venkatesh, C.2


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