Substituted salicylanilides as inhibitors of two-component regulatory systems in bacteria

Journal of Medicinal Chemistry

Volumn 41, Issue 16, 1998, Pages 2939-2945

  Macielag, Mark J ^a   Demers, James P ^a   Fraga Spano, Stephanie A ^a   Hlasta, Dennis J ^a   Johnson, Sigmond G ^a   Kanojia, Ramesh M ^a   Russell, Ronald K ^a   Sui, Zhihua ^a   Weidner Wells, Michele A ^a   Werblood, Harvey ^a   Foleno, Barbara D ^a   Goldschmidt, Raul M ^a   Loeloff, Michael J ^a   Webb, Glenda C ^a   Barrett, John F ^a,b  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CLOSANTEL; METICILLIN; N (3,4 DICHLOROPHENYL) 2 HYDROXY 3,5 BIS(TRIFLUOROMETHYL)BENZAMIDE; N (3,4 DICHLOROPHENYL) 2 HYDROXY 3,5 DIIODOBENZAMIDE; N (3,4 DICHLOROPHENYL) 2,3 DIHYDROXYBENZAMIDE; N (4 CHLORO 3 TRIFLUOROMETHYLPHENYL) 3,5 DICHLORO 2 HYDROXYBENZAMIDE; N [5 CHLORO 4 [(4 CHLOROPHENYL)CYANOMETHYL] 2 METHYLPHENYL] 2 HYDROXY 5 (TRIFLUOROMETHYL)BENZAMIDE; N [5 CHLORO 4 [(4 CHLOROPHENYL)CYANOMETHYL] 2 METHYLPHENYL] 2,3 DIHYDROXYBENZAMIDE; N [5 CHLORO 4 [(4 CHLOROPHENYL)CYANOMETHYL] 2 METHYLPHENYL] 3,5 DICHLORO 2 HYDROXYBENZAMIDE; PROTEIN KINASE; SALICYLANILIDE DERIVATIVE; TETRACHLORSALAN; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; AUTOPHOSPHORYLATION; CONCENTRATION RESPONSE; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; REGULATORY MECHANISM; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BACTERIAL PROTEINS; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, MICROBIAL; ENTEROCOCCUS FAECIUM; ENZYME INHIBITORS; GRAM-POSITIVE BACTERIA; LUCIFERASES; METHICILLIN RESISTANCE; MICROBIAL SENSITIVITY TESTS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; SALICYLANILIDES; SPORES, BACTERIAL; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; VANCOMYCIN;

EID: 15444355645     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9803572     Document Type: Article

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