In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis

Journal of Antimicrobial Chemotherapy

Volumn 49, Issue 1, 2002, Pages 103-111

  Adagu, I Sullayman ^a   Nolder, Deborah ^a   Warhurst, David C ^a   Rossignol, Jean François ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; DENITRONITAZOXANIDE; DENITROTIZOXANIDE; DRUG METABOLITE; FREE RADICAL; METRONIDAZOLE; NITAZOXANIDE; TIZOXANIDE; TIZOXANIDE GLUCURONIDE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SENSITIVITY; DRUG STRUCTURE; ENTAMOEBA HISTOLYTICA; GIARDIA LAMBLIA; IN VITRO STUDY; NONHUMAN; STRAIN DIFFERENCE; TRICHOMONAS VAGINALIS;

EID: 0036156713     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/49.1.103     Document Type: Article

References (43)

1. Model Prescribing Information: Drugs Used in Parasitic Diseases
2. Recurrence of hepatic amebiasis after successful treatment with metronidazole
3. Oxygen affinities of metronidazole-resistant and -sensitive stocks of Giardia intestinalis
4. Efficacy of new 5-nitroimidazoles against metronidazole-susceptible and -resistant Giardia, Trichomonas, and Entamoeba spp
5. Trichomonas vaginalis and amplification of HIV-1 transmission
6. New derivative of 2-benzamido-5-nitro thiazoles
7. Synthesis and anti-bacterial activities of tizoxanide, a N-nitrothiazolyl salicylamide, and its O-aryl glucuronide
8. Nitazoxanide: Pharmacokinetics and metabolism in man
9. The efficacy of nitazoxanide against Cryptosporidium parvum in cell culture and in animal models
10. Comparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide and paromomycin against Cryptosporidium parvum infections in a neonatal mouse model
11. Efficacy of nitazoxanide, tizoxanide and tizoxanide glucuronide against Cryptosporidium parvum development in sporozoite-infected HCT-8 enterocytic cells
12. Screening of compounds for antimicrosporidial activity in vitro
13. Etude de diverses associations d'anthelminthiques chez la souris
14. Experimentation des proprietes anthelminthiques de la nitazoxanide chez le chien, le chat, et les ovins
15. Vitro evaluation of activities of nitazoxanide and tizoxanide against anaerobes and aerobic organisms
16. Nitazoxanide, a potential drug to eradicate Helicobacter pylori with no cross resistance to metronidazole
17. Nitazoxanide in the treatment of cryptosporidial diarrhoea and other intestinal parasitic infections associated with acquired immunodeficiency syndrome in tropical Africa
18. Treatment of diarrhea caused by Cryptosporidium parvum: A prospective randomized, double-blind, placebo-controlled study of nitazoxanide
19. Successful treatment with nitazoxanide of Enterocytozoon bieneusi microsporidiosis in a patient with AIDS
20. Nitazoxanide for the treatment of intestinal protozoan and helminthic infections in Mexico
21. Nitazoxanide in the treatment of Taenia saginata and Hymenolepis nana
22. Successful treatment of heavily infected human fascioliasis with nitazoxanide: A case report
23. Hatching and subsequent cultivation of cysts of Giardia intestinalis in Diamond's medium
24. Considerations sur l'action pathogene d'une souche d'amibes dysenterique (Souche C. Dobell DKB)
25. Susceptibility testing of Entamoeba histolytica
26. Viruses of Entamoeba histolytica: Identification of transmissible virus-like agents
27. Intraspecific variation and phylogenetic relationships in the genus Entamoeba as revealed by riboprinting
28. Isolation and axenization of two Entamoeba histolytica strains
29. A comparative study of Entamoeba histolytica (NIH 200, HK9 etc) 'E. histolytica-like' and other morphologically identical amoebae using isoenzyme electrophoresis
30. A comparison of the virulence of nine strains of axenically cultivated E. histolytica in the hamster liver
31. Vitro sensitivity of Entamoeba histolytica to metronidazole
32. Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids
33. Vitro susceptibility of Trichomonas vaginalis to metronidazole and treatment outcome in vaginal trichomoniasis
34. A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba
35. Axenic culture of Giardia lamblia in TYI-S-33 medium supplemented with bile
36. Resistance of Trichomonas vaginalis to metronidazole: Report of the first three cases from Finland and optimization of in vitro susceptibility testing under various oxygen concentrations
37. Comparison of the in vitro activities of quassinoids with activity against Plasmodium falciparum, anisomycin and some other inhibitors of eukaryotic protein synthesis
38. Plants as sources of antimalarial drugs. Part 1. In Vitro test method for the evaluation of crude extracts from plants
39. Drug susceptibility testing of anaerobic protozoa
40. Nitroimidazole drugs-action and resistance mechanisms. I. Mechanisms of action
41. Drug targets and mechanisms of resistance in the anaerobic protozoa
42. Some reactions and properties of nitro radical-anions important in biology and medicine
43. Pyruvate:NADP oxidoreductase from the mitochondrion of Euglena gracilis and from the Apicomplexan Cryptosporidium parvum: A biochemical relic linking pyruvate metabolism in mitochondriate and amitochondriate protists