Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 10, 2004, Pages 2517-2521

  Zhang, Xue Wu ^a   Yap, Yee Leng ^a  

^a HKU PASTEUR RESEARCH CENTRE   (Hong Kong)

Author keywords

Binding; Drugs; Proteinase; SARS CoV

Indexed keywords

ANTIVIRUS AGENT; LOPINAVIR; NICLOSAMIDE; PROMAZINE; PROTEINASE; PROTEINASE INHIBITOR; RITONAVIR; UC 2; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS; PREDICTION; SARS CORONAVIRUS; VIRUS INHIBITION; VIRUS REPLICATION;

ANTI-HIV AGENTS; ANTIPARASITIC AGENTS; ANTIPSYCHOTIC AGENTS; ANTIVIRAL AGENTS; CYSTEINE ENDOPEPTIDASES; DRUG DESIGN; FURANS; MOLECULAR STRUCTURE; NICLOSAMIDE; PROMAZINE; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PYRIMIDINES; PYRIMIDINONES; RITONAVIR; SEVERE ACUTE RESPIRATORY SYNDROME;

CORONAVIRUS; SARS CORONAVIRUS;

EID: 2142657824     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.03.035     Document Type: Article

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