Biological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanide

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 12, 2010, Pages 3537-3539

  Ballard, T Eric ^a   Wang, Xia ^b   Olekhnovich, Igor ^b   Koerner, Taylor ^a   Seymour, Craig ^a   Hoffman, Paul S ^b   MacDonald, Timothy L ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Antibacterial; Campylobacter jejuni; Clostridium difficile; Helicobacter pylori; Nitazoxanide; Pyruvate:ferredoxin oxidoreductase; Small molecule drug target

Indexed keywords

2 AMINO 5 NITROTHIAZOLE AMIDE; ANTIINFECTIVE AGENT; METRONIDAZOLE; NITAZOXANIDE; PYRUVATE SYNTHASE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BIOLOGICAL ACTIVITY; CAMPYLOBACTER JEJUNI; CHEMICAL MODIFICATION; CLOSTRIDIUM DIFFICILE; DRUG SYNTHESIS; ESCHERICHIA COLI; GROWTH INHIBITION; HELICOBACTER PYLORI; NONHUMAN;

ANTI-BACTERIAL AGENTS; ANTIPARASITIC AGENTS; CAMPYLOBACTER JEJUNI; CLOSTRIDIUM DIFFICILE; HELICOBACTER PYLORI; PYRUVATE SYNTHASE; SMALL MOLECULE LIBRARIES; THIAZOLES;

CAMPYLOBACTER JEJUNI; CLOSTRIDIUM DIFFICILE; HELICOBACTER PYLORI;

EID: 77954218167     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.126     Document Type: Article

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