Amide-containing diketoacids as HIV-1 integrase inhibitors: Synthesis, structure-activity relationship analysis, and biological activity

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 7, 2009, Pages 2913-2919

  Li, Hongcai ^a   Wang, Chao ^a   Sanchez, Tino ^b   Tan, Yanmei ^a   Jiang, Chunying ^a   Neamati, Nouri ^b   Zhao, Guisen ^a  

^a SHANDONG UNIVERSITY   (China)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Diketoacids; HIV; Integrase inhibitors; Structure activity relationship

Indexed keywords

AMIDE; DIKETOACID DERIVATIVE; INTEGRASE; INTEGRASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION;

AMIDES; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; KETO ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 62949189676     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.01.077     Document Type: Article

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