Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus

Journal of Medicinal Chemistry

Volumn 50, Issue 17, 2007, Pages 4087-4095

  Wen, Chih Chun ^a,b   Kuo, Yueh Hsiung ^b,c   Jan, Jia Tsrong ^d   Liang, Po Huang ^e   Wang, Sheng Yang ^f   Liu, Hong Gi ^e   Lee, Ching Kuo ^g   Chang, Shang Tzen ^c   Kuo, Chih Jung ^e   Lee, Shoei Sheng ^c   Hou, Chia Chung ^a   Hsiao, Pei Wen ^a   Chien, Shih Chang ^a   Shyur, Lie Fen ^a,h   Yang, Ning Sun ^a,h  

^a AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL DEFENSE UNIVERSITY   (Taiwan)

^e INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^f NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^g TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^h NONE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA,12 DIACETOXYABIETA 6,8,11,13 TETRAENE; 6,7 DEHYDROROYLEANONE; 7BETA HYDROXYDEOXYCRYPTOJAPONOL; 8BETA HYDROXYABIETA 9(11),13 DIEN 12 ONE; ALPHA CADINOL; BETULIC ACID; BETULONIC ACID; CEDRANE 3BETA,12 DIOL; CRYPTOJAPONOL; CURCUMIN; DEHYDROABIETA 7 ONE; FERRUGINOL; FORSKOLIN; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; HINOKININ; LIGNOID DERIVATIVE; MAGNOLOL; NICLOSAMIDE; PINUSOLIDIC ACID; PROTEINASE; SAVININ; SESQUITERPENOID; SUGIOL; TERPENOID DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG; VALINOMYCIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SAFETY; IC 50; NONHUMAN; PHYTOCHEMISTRY; SARS CORONAVIRUS; STRUCTURE ACTIVITY RELATION; VERO CELL; VIRUS INHIBITION; VIRUS REPLICATION;

ANIMALS; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; CYSTEINE ENDOPEPTIDASES; LIGNANS; MODELS, MOLECULAR; PLANTS, MEDICINAL; SARS VIRUS; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES; TRITERPENES; VERO CELLS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 34548125311     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm070295s     Document Type: Article

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