Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease

Journal of Medicinal Chemistry

Volumn 48, Issue 13, 2005, Pages 4469-4473

  Shie, Jiun Jie ^a   Fang, Jim Min ^a,b   Kuo, Chih Jung ^c   Kuo, Tun Hsun ^c   Liang, Po Huang ^c   Huang, Hung Jyun ^a   Yang, Wen Bin ^b   Lin, Chun Hung ^c   Chen, Jiun Ling ^a   Wu, Yin Ta ^b   Wong, Chi Huey ^b,d  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (DIMETHYLAMINO)BENZOYL PHENYLALANINE (2 CHLORO 4 NITROANILIDE); ANILIDE; PROTEINASE; PROTEINASE INHIBITOR; RUPINTRIVIR; UNCLASSIFIED DRUG; VIRUS ENZYME;

ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG ACTIVITY; DRUG INHIBITION; DRUG STRUCTURE; SARS CORONAVIRUS;

ANILIDES; ANTIVIRAL AGENTS; CYSTEINE ENDOPEPTIDASES; ENDOPEPTIDASES; KINETICS; MODELS, MOLECULAR; PROTEASE INHIBITORS; PROTEIN CONFORMATION; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS;

EID: 21244442337     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050184y     Document Type: Article

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