Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes

Journal of Antimicrobial Chemotherapy

Volumn 65, Issue 3, 2010, Pages 512-519

  Stadelmann, Britta ^a   Scholl, Sabrina ^a   Müller, Joachim ^a   Hemphill, Andrew ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Alveolar echinococcosis; Chemotherapy; In vitro culture; Medium throughput drug screening

Indexed keywords

ALBENDAZOLE; GLUCOSE 6 PHOSPHATE ISOMERASE; MEBENDAZOLE; NITAZOXANIDE; RM 4802; RM 4803; RM 4804; RM 4805; RM 4806; RM 4807; RM 4808; RM 4819; RM 4820; RM 4821; RM 4822; RM 4824; RM 4827; RM 4828; RM 4829; RM 4830; RM 4831; RM 4833; RM 4834; RM 4835; RM 4836; RM 4837; RM 4838; SUPEROXIDE DISMUTASE; THIAZOLE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; DRUG EFFICACY; ECHINOCOCCUS MULTILOCULARIS; ENZYME ACTIVITY; ENZYME RELEASE; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; METACESTODE; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUPERNATANT; TREATMENT INDICATION;

ANIMALS; ANTHELMINTICS; CULTURE MEDIA; DRUG EVALUATION, PRECLINICAL; ECHINOCOCCUS MULTILOCULARIS; GLUCOSE-6-PHOSPHATE ISOMERASE; HELMINTH PROTEINS; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TIME FACTORS;

EID: 77950316746     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkp490     Document Type: Article

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