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Volumn 82, Issue 8, 2011, Pages 891-903

Targeting the nicotinic alpha7 acetylcholine receptor to enhance cognition in disease

Author keywords

Alzheimer's; Attention; Cognitive; Memory; Nicotine; Schizophrenia

Indexed keywords

1,2,3,5 TETRAHYDRO 5 METHYL 1 (3 PYRIDYLCARBAMOYL)PYRROLO[2,3 F]INDOLE; 1,4 DIAZABICYCLO[3.2.2]NONANE 4 CARBOXYLIC ACID 4 BROMOPHENYL ESTER; 3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; 4 CHLORO N (3 QUINUCLIDINYL)BENZAMIDE; A 582941; A 867744; ABT 107; ALPHA METHYLLYCACONITINE; AR R17779; ARR 17779; AZD 0328; BUNGAROTOXIN RECEPTOR; CHOLINE; EVP 6124; JN 403; JNJ 1930942; MECAMYLAMINE; N (1 AZABICYCLO[3.2.1]OCT 3 YL)FURO[2,3 C]PYRIDINE 5 CARBOXAMIDE; N (3 QUINUCLIDINYL)FURO[2,3 C]PYRIDINE 5 CARBOXAMIDE; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NS 1738; PHA 568487; PNU 120596; RG 3487; S 24795; SEN 12333; TC 5619; UNCLASSIFIED DRUG; UNINDEXED DRUG; XY 4083;

EID: 80052028010     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.06.034     Document Type: Conference Paper
Times cited : (194)

References (168)
  • 1
    • 35348967477 scopus 로고    scopus 로고
    • Relevance of donepezil in enhancing learning and memory in special populations: A review of the literature
    • DOI 10.1007/s10803-006-0322-8
    • J.H. Yoo, M.G. Valdovinos, and D.C. Williams Relevance of donepezil in enhancing learning and memory in special populations: a review of the literature J Autism Dev Disord 37 2007 1883 1901 (Pubitemid 47609347)
    • (2007) Journal of Autism and Developmental Disorders , vol.37 , Issue.10 , pp. 1883-1901
    • Yoo, J.H.1    Valdovinos, M.G.2    Williams, D.C.3
  • 2
    • 47749150634 scopus 로고    scopus 로고
    • A systematic review of off-label uses of memantine for psychiatric disorders
    • DOI 10.1016/j.pnpbp.2008.01.008, PII S0278584608000237
    • K. Zdanys, and R.R. Tampi A systematic review of off-label uses of memantine for psychiatric disorders Prog Neuropsychopharmacol Biol Psychiatry 32 2008 1362 1374 (Pubitemid 352033662)
    • (2008) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.32 , Issue.6 , pp. 1362-1374
    • Zdanys, K.1    Tampi, R.R.2
  • 3
    • 77949771090 scopus 로고    scopus 로고
    • Cholinesterase inhibitors as adjunctive therapy in patients with schizophrenia and schizoaffective disorder: A review and meta-analysis of the literature
    • S.R. Ribeiz, D.P. Bassitt, J.A. Arrais, R. Avila, D.C. Steffens, and C.M. Bottino Cholinesterase inhibitors as adjunctive therapy in patients with schizophrenia and schizoaffective disorder: a review and meta-analysis of the literature CNS Drugs 24 2010 303 317
    • (2010) CNS Drugs , vol.24 , pp. 303-317
    • Ribeiz, S.R.1    Bassitt, D.P.2    Arrais, J.A.3    Avila, R.4    Steffens, D.C.5    Bottino, C.M.6
  • 4
    • 0035251680 scopus 로고    scopus 로고
    • Cognitive effects of nicotine
    • DOI 10.1016/S0006-3223(00)01094-5, PII S0006322300010945
    • A.H. Rezvani, and E.D. Levin Cognitive effects of nicotine Biol Psychiatry 49 2001 258 267 (Pubitemid 32178435)
    • (2001) Biological Psychiatry , vol.49 , Issue.3 , pp. 258-267
    • Rezvani, A.H.1    Levin, E.D.2
  • 6
    • 33747422892 scopus 로고    scopus 로고
    • Brain nicotinic acetylcholine receptors: native subtypes and their relevance
    • DOI 10.1016/j.tips.2006.07.004, PII S0165614706001751
    • C. Gotti, M. Zoli, and F. Clementi Brain nicotinic acetylcholine receptors: native subtypes and their relevance Trends Pharmacol Sci 27 2006 482 491 (Pubitemid 44251225)
    • (2006) Trends in Pharmacological Sciences , vol.27 , Issue.9 , pp. 482-491
    • Gotti, C.1    Zoli, M.2    Clementi, F.3
  • 7
    • 33847029091 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
    • J.A. Dani, and D. Bertrand Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system Annu Rev Pharmacol Toxicol 47 2007 699 729
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 699-729
    • Dani, J.A.1    Bertrand, D.2
  • 8
    • 69949159308 scopus 로고    scopus 로고
    • Nicotinic receptors: Allosteric transitions and therapeutic targets in the nervous system
    • A. Taly, P.J. Corringer, D. Guedin, P. Lestage, and J.P. Changeux Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system Nat Rev Drug Discov 8 2009 733 750
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 733-750
    • Taly, A.1    Corringer, P.J.2    Guedin, D.3    Lestage, P.4    Changeux, J.P.5
  • 9
    • 34548677767 scopus 로고    scopus 로고
    • Allosteric modulation of nicotinic acetylcholine receptors
    • DOI 10.1016/j.bcp.2007.07.011, PII S0006295207004637
    • D. Bertrand, and M. Gopalakrishnan Allosteric modulation of nicotinic acetylcholine receptors Biochem Pharmacol 74 2007 1155 1163 (Pubitemid 47417931)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.8 , pp. 1155-1163
    • Bertrand, D.1    Gopalakrishnan, M.2
  • 10
    • 0022972567 scopus 로고
    • α-Bungarotoxin binds to low-affinity nicotine binding sites in rat brain
    • DOI 10.1111/j.1471-4159.1986.tb13078.x
    • S. Wonnacott alpha-Bungarotoxin binds to low-affinity nicotine binding sites in rat brain J Neurochem 47 1986 1706 1712 (Pubitemid 17191481)
    • (1986) Journal of Neurochemistry , vol.47 , Issue.6 , pp. 1706-1712
    • Wonnacott, S.1
  • 11
    • 0038771243 scopus 로고    scopus 로고
    • Co-expression of α7 and β2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons
    • DOI 10.1016/S0306-4522(03)00220-3
    • L. Azam, U. Winzer-Serhan, and F.M. Leslie Co-expression of alpha7 and beta2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons Neuroscience 119 2003 965 977 (Pubitemid 36776447)
    • (2003) Neuroscience , vol.119 , Issue.4 , pp. 965-977
    • Azam, L.1    Winzer-Serhan, U.2    Leslie, F.M.3
  • 12
    • 59649090731 scopus 로고    scopus 로고
    • A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides
    • Q. Liu, Y. Huang, F. Xue, A. Simard, J. DeChon, and G. Li A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides J Neurosci 29 2009 918 929
    • (2009) J Neurosci , vol.29 , pp. 918-929
    • Liu, Q.1    Huang, Y.2    Xue, F.3    Simard, A.4    Dechon, J.5    Li, G.6
  • 13
    • 0021909380 scopus 로고
    • 125I]- α-bungarotoxin
    • P.B. Clarke, R.D. Schwartz, S.M. Paul, C.B. Pert, and A. Pert Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine [3H]nicotine, and [125I]-alpha-bungarotoxin J Neurosci 5 1985 1307 1315 (Pubitemid 15098442)
    • (1985) Journal of Neuroscience , vol.5 , Issue.5 , pp. 1307-1315
    • Clarke, P.B.S.1    Schwartz, R.D.2    Paul, S.M.3
  • 14
    • 0027518923 scopus 로고
    • 7: A nicotinic cation channel highly permeable to calcium
    • P. Seguela, J. Wadiche, K. Dineley-Miller, J.A. Dani, and J.W. Patrick Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium J Neurosci 13 1993 596 604 (Pubitemid 23045143)
    • (1993) Journal of Neuroscience , vol.13 , Issue.2 , pp. 596-604
    • Seguela, P.1    Wadiche, J.2    Dineley-Miller, K.3    Dani, J.A.4    Patrick, J.W.5
  • 15
    • 1242272110 scopus 로고    scopus 로고
    • Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: An autoradiographic study in the rat brain
    • DOI 10.1016/j.neuroscience.2003.09.028
    • E. Tribollet, D. Bertrand, A. Marguerat, and M. Raggenbass Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain Neuroscience 124 2004 405 420 (Pubitemid 38229660)
    • (2004) Neuroscience , vol.124 , Issue.2 , pp. 405-420
    • Tribollet, E.1    Bertrand, D.2    Marguerat, A.3    Raggenbass, M.4
  • 16
    • 0026475948 scopus 로고
    • Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: Localization of alpha 3 subunit mRNA, alpha-bungarotoxin and nicotine binding sites
    • M. Cimino, P. Marini, D. Fornasari, F. Cattabeni, and F. Clementi Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: localization of alpha 3 subunit mRNA, alpha-bungarotoxin and nicotine binding sites Neuroscience 51 1992 77 86
    • (1992) Neuroscience , vol.51 , pp. 77-86
    • Cimino, M.1    Marini, P.2    Fornasari, D.3    Cattabeni, F.4    Clementi, F.5
  • 19
    • 79952167906 scopus 로고    scopus 로고
    • The thalamic reticular nucleus and schizophrenia
    • F. Ferrarelli, and G. Tononi The thalamic reticular nucleus and schizophrenia Schizophr Bull 37 2011 306 315
    • (2011) Schizophr Bull , vol.37 , pp. 306-315
    • Ferrarelli, F.1    Tononi, G.2
  • 20
    • 10644254858 scopus 로고    scopus 로고
    • Precise localization of α7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area
    • DOI 10.1523/JNEUROSCI.3009-04.2004
    • I.W. Jones, and S. Wonnacott Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area J Neurosci 24 2004 11244 11252 (Pubitemid 39658259)
    • (2004) Journal of Neuroscience , vol.24 , Issue.50 , pp. 11244-11252
    • Jones, I.W.1    Wonnacott, S.2
  • 21
    • 21344459009 scopus 로고    scopus 로고
    • 3H]D-aspartate release from rat frontal cortex in vitro
    • DOI 10.1016/j.neuropharm.2005.01.030, PII S0028390805000687
    • S.J. Rousseau, I.W. Jones, I.A. Pullar, and S. Wonnacott Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro Neuropharmacology 49 2005 59 72 (Pubitemid 40910016)
    • (2005) Neuropharmacology , vol.49 , Issue.1 , pp. 59-72
    • Rousseau, S.J.1    Jones, I.W.2    Pullar, I.A.3    Wonnacott, S.4
  • 22
    • 0036325889 scopus 로고    scopus 로고
    • Direct evidence that release-stimulating α7*nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals
    • DOI 10.1046/j.0022-3042.2002.00805.x
    • M. Marchi, F. Risso, C. Viola, P. Cavazzani, and M. Raiteri Direct evidence that release-stimulating alpha7* nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals J Neurochem 80 2002 1071 1078 (Pubitemid 34809959)
    • (2002) Journal of Neurochemistry , vol.80 , Issue.6 , pp. 1071-1078
    • Marchi, M.1    Risso, F.2    Viola, C.3    Cavazzani, P.4    Raiteri, M.5
  • 23
    • 75049084941 scopus 로고    scopus 로고
    • Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by Alpha7 nicotinic receptors and potentiated by PNU-120596
    • P.D. Livingstone, J.A. Dickinson, J. Srinivasan, J.N. Kew, and S. Wonnacott Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by Alpha7 nicotinic receptors and potentiated by PNU-120596 J Mol Neurosci 40 2010 172 176
    • (2010) J Mol Neurosci , vol.40 , pp. 172-176
    • Livingstone, P.D.1    Dickinson, J.A.2    Srinivasan, J.3    Kew, J.N.4    Wonnacott, S.5
  • 24
    • 67349269521 scopus 로고    scopus 로고
    • Spatial and intracellular relationships between the alpha7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse
    • A.M. Duffy, P. Zhou, T.A. Milner, and V.M. Pickel Spatial and intracellular relationships between the alpha7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse Neuroscience 161 2009 1091 1103
    • (2009) Neuroscience , vol.161 , pp. 1091-1103
    • Duffy, A.M.1    Zhou, P.2    Milner, T.A.3    Pickel, V.M.4
  • 25
    • 47149106256 scopus 로고    scopus 로고
    • Preclinical characterization of A-582941: A novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties
    • K.R. Tietje, D.J. Anderson, R.S. Bitner, E.A. Blomme, P.J. Brackemeyer, and C.A. Briggs Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties CNS Neurosci Ther 14 2008 65 82
    • (2008) CNS Neurosci Ther , vol.14 , pp. 65-82
    • Tietje, K.R.1    Anderson, D.J.2    Bitner, R.S.3    Blomme, E.A.4    Brackemeyer, P.J.5    Briggs, C.A.6
  • 27
    • 68349141648 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and the ascending dopamine pathways
    • P.D. Livingstone, and S. Wonnacott Nicotinic acetylcholine receptors and the ascending dopamine pathways Biochem Pharmacol 78 2009 744 755
    • (2009) Biochem Pharmacol , vol.78 , pp. 744-755
    • Livingstone, P.D.1    Wonnacott, S.2
  • 28
    • 0030858491 scopus 로고    scopus 로고
    • Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex
    • K.L. Summers, W.R. Kem, and E. Giacobini Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex Jpn J Pharmacol 74 1997 139 146 (Pubitemid 27331139)
    • (1997) Japanese Journal of Pharmacology , vol.74 , Issue.2 , pp. 139-146
    • Summers, K.L.1    Kem, W.R.2    Giacobini, E.3
  • 29
    • 0019890828 scopus 로고
    • Calcium and the control of synaptic strength by learning
    • E.R. Kandel Calcium and the control of synaptic strength by learning Nature 293 1981 697 700
    • (1981) Nature , vol.293 , pp. 697-700
    • Kandel, E.R.1
  • 30
    • 33846783267 scopus 로고    scopus 로고
    • Differential coupling of α7 and non-α7 nicotinic acetylcholine receptors to calcium-induced calcium release and voltage-operated calcium channels in PC12 cells
    • DOI 10.1111/j.1471-4159.2006.04273.x
    • J.A. Dickinson, K.E. Hanrott, M.H. Mok, J.N. Kew, and S. Wonnacott Differential coupling of alpha7 and non-alpha7 nicotinic acetylcholine receptors to calcium-induced calcium release and voltage-operated calcium channels in PC12 cells J Neurochem 100 2007 1089 1096 (Pubitemid 46213931)
    • (2007) Journal of Neurochemistry , vol.100 , Issue.4 , pp. 1089-1096
    • Dickinson, J.A.1    Hanrott, K.E.2    Mok, M.H.S.3    Kew, J.N.C.4    Wonnacott, S.5
  • 31
    • 0033118561 scopus 로고    scopus 로고
    • Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices
    • M. Alkondon, E.F. Pereira, and H.M. Eisenberg Albuquerque EX. Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices J Neurosci 19 1999 2693 2705 (Pubitemid 29162417)
    • (1999) Journal of Neuroscience , vol.19 , Issue.7 , pp. 2693-2705
    • Alkondon, M.1    Pereira, E.F.R.2    Eisenberg, H.M.3    Albuquerque, E.X.4
  • 32
    • 0033995561 scopus 로고    scopus 로고
    • Nicotinic receptor activation in human cerebral cortical interneurons: A mechanism for inhibition and disinhibition of neuronal networks
    • M. Alkondon, E.F. Pereira, and H.M. Eisenberg Albuquerque EX. Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for inhibition and disinhibition of neuronal networks J Neurosci 20 2000 66 75 (Pubitemid 30220492)
    • (2000) Journal of Neuroscience , vol.20 , Issue.1 , pp. 66-75
    • Alkondon, M.1    Pereira, E.F.R.2    Eisenberg, H.M.3    Albuquerque, E.X.4
  • 34
    • 2542486433 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and the regulation of neuronal signalling
    • DOI 10.1016/j.tips.2004.04.006, PII S016561470400118X
    • F. Dajas-Bailador, and S. Wonnacott Nicotinic acetylcholine receptors and the regulation of neuronal signalling Trends Pharmacol Sci 25 2004 317 324 (Pubitemid 38692424)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.6 , pp. 317-324
    • Dajas-Bailador, F.1    Wonnacott, S.2
  • 35
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • DOI 10.1038/361031a0
    • T.V. Bliss, and G.L. Collingridge A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 1993 31 39 (Pubitemid 23020772)
    • (1993) Nature , vol.361 , Issue.6407 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 36
    • 33845676294 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus
    • DOI 10.1111/j.1460-9568.2006.05187.x
    • P. Welsby, M. Rowan, and R. Anwyl Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus Eur J Neurosci 24 2006 3109 3118 (Pubitemid 44952643)
    • (2006) European Journal of Neuroscience , vol.24 , Issue.11 , pp. 3109-3118
    • Welsby, P.1    Rowan, M.2    Anwyl, R.3
  • 37
    • 34547165139 scopus 로고    scopus 로고
    • Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP
    • DOI 10.1016/j.neuropharm.2007.05.013, PII S0028390807001505
    • P.J. Welsby, M.J. Rowan, and R. Anwyl Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP Neuropharmacology 53 2007 188 195 (Pubitemid 47125959)
    • (2007) Neuropharmacology , vol.53 , Issue.1 , pp. 188-195
    • Welsby, P.J.1    Rowan, M.J.2    Anwyl, R.3
  • 38
    • 78650797928 scopus 로고    scopus 로고
    • RG3487, a novel nicotinic alpha 7 receptor partial agonist, improves cognition and sensorimotor gating in rodents
    • T.L. Wallace, P.M. Callahan, A. Tehim, D. Bertrand, G. Tombaugh, and S. Wang RG3487, a novel nicotinic alpha 7 receptor partial agonist, improves cognition and sensorimotor gating in rodents J Pharmacol Exp Ther 336 2011 242 253
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 242-253
    • Wallace, T.L.1    Callahan, P.M.2    Tehim, A.3    Bertrand, D.4    Tombaugh, G.5    Wang, S.6
  • 40
    • 0028108923 scopus 로고
    • CREB: A mediator of long-term memory from mollusks to mammals
    • DOI 10.1016/0092-8674(94)90394-8
    • D.A. Frank, and M.E. Greenberg CREB: a mediator of long-term memory from mollusks to mammals Cell 79 1994 5 8 (Pubitemid 24309507)
    • (1994) Cell , vol.79 , Issue.1 , pp. 5-8
    • Frank, D.A.1    Greenberg, M.E.2
  • 41
    • 46549086401 scopus 로고    scopus 로고
    • The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat
    • M.S. Thomsen, J.D. Mikkelsen, D.B. Timmermann, D. Peters, A. Hay-Schmidt, and H. Martens The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: differential effects in the juvenile and adult rat Neuroscience 154 2008 741 753
    • (2008) Neuroscience , vol.154 , pp. 741-753
    • Thomsen, M.S.1    Mikkelsen, J.D.2    Timmermann, D.B.3    Peters, D.4    Hay-Schmidt, A.5    Martens, H.6
  • 42
    • 0036891571 scopus 로고    scopus 로고
    • Desensitization of neuronal nicotinic receptors
    • DOI 10.1002/neu.10109
    • M.W. Quick, and R.A. Lester Desensitization of neuronal nicotinic receptors J Neurobiol 53 2002 457 478 (Pubitemid 35375579)
    • (2002) Journal of Neurobiology , vol.53 , Issue.4 , pp. 457-478
    • Quick, M.W.1    Lester, R.A.J.2
  • 43
    • 0034602138 scopus 로고    scopus 로고
    • Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons
    • A. Mike, N.G. Castro, and E.X. Albuquerque Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons Brain Res 882 2000 155 168
    • (2000) Brain Res , vol.882 , pp. 155-168
    • Mike, A.1    Castro, N.G.2    Albuquerque, E.X.3
  • 44
    • 20744449198 scopus 로고    scopus 로고
    • Desensitization of nicotinic ACh receptors: Shaping cholinergic signaling
    • DOI 10.1016/j.tins.2005.04.009, PII S0166223605001098
    • R. Giniatullin, A. Nistri, and J.L. Yakel Desensitization of nicotinic ACh receptors: shaping cholinergic signaling Trends Neurosci 28 2005 371 378 (Pubitemid 40853860)
    • (2005) Trends in Neurosciences , vol.28 , Issue.7 , pp. 371-378
    • Giniatullin, R.1    Nistri, A.2    Yakel, J.L.3
  • 45
    • 0041377930 scopus 로고    scopus 로고
    • Nicotine as a modulator of behavior: Beyond the inverted U
    • DOI 10.1016/S0165-6147(03)00230-X
    • M.R. Picciotto Nicotine as a modulator of behavior: beyond the inverted U Trends Pharmacol Sci 24 2003 493 499 (Pubitemid 37088175)
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.9 , pp. 493-499
    • Picciotto, M.R.1
  • 47
    • 59649098711 scopus 로고    scopus 로고
    • Desensitization of nicotinic acetylcholine receptors as a strategy for drug development
    • J.J. Buccafusco, J.W. Beach, and A.V. Terry Jr. Desensitization of nicotinic acetylcholine receptors as a strategy for drug development J Pharmacol Exp Ther 328 2009 364 370
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 364-370
    • Buccafusco, J.J.1    Beach, J.W.2    Terry, Jr.A.V.3
  • 48
    • 0034724994 scopus 로고    scopus 로고
    • Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region
    • DOI 10.1016/S0006-8993(00)02119-3, PII S0006899300021193
    • S. Fujii, Y. Jia, A. Yang, and K. Sumikawa Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region Brain Res 863 2000 259 265 (Pubitemid 30201607)
    • (2000) Brain Research , vol.863 , Issue.1-2 , pp. 259-265
    • Fujii, S.1    Jia, Y.2    Yang, A.3    Sumikawa, K.4
  • 49
    • 0033372817 scopus 로고    scopus 로고
    • Differential improvement in memory-related task performance with nicotine by aged male and female rhesus monkeys
    • J.J. Buccafusco, W.J. Jackson, R.R. Jonnala, and A.V. Terry Jr. Differential improvement in memory-related task performance with nicotine by aged male and female rhesus monkeys Behav Pharmacol 10 1999 681 690 (Pubitemid 30026063)
    • (1999) Behavioural Pharmacology , vol.10 , Issue.6-7 , pp. 681-690
    • Buccafusco, J.J.1    Jackson, W.J.2    Jonnala, R.R.3    Terry Jr., A.V.4
  • 51
    • 65649092520 scopus 로고    scopus 로고
    • Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders
    • R. Roncarati, C. Scali, T.A. Comery, S.M. Grauer, S. Aschmi, and H. Bothmann Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders J Pharmacol Exp Ther 329 2009 459 468
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 459-468
    • Roncarati, R.1    Scali, C.2    Comery, T.A.3    Grauer, S.M.4    Aschmi, S.5    Bothmann, H.6
  • 53
    • 0030011343 scopus 로고    scopus 로고
    • Comparison of the effects of the 5-HT3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic projection system
    • H. Hodges, P. Sowinski, J.J. Turner, and A. Fletcher Comparison of the effects of the 5-HT3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic projection system Psychopharmacology (Berl) 125 1996 146 161
    • (1996) Psychopharmacology (Berl) , vol.125 , pp. 146-161
    • Hodges, H.1    Sowinski, P.2    Turner, J.J.3    Fletcher, A.4
  • 54
    • 0030976574 scopus 로고    scopus 로고
    • Different effects of tropisetron and ondansetron in learning and memory paradigms
    • DOI 10.1016/S0091-3057(96)00516-3, PII S0091305796005163
    • N. Pitsikas, and F. Borsini Different effects of tropisetron and ondansetron in learning and memory paradigms Pharmacol Biochem Behav 56 1997 571 576 (Pubitemid 27189738)
    • (1997) Pharmacology Biochemistry and Behavior , vol.56 , Issue.4 , pp. 571-576
    • Pitsikas, N.1    Borsini, F.2
  • 55
    • 0028934741 scopus 로고
    • Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21
    • G.W. Arendash, G.J. Sengstock, P.R. Sanberg, and W.R. Kem Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21 Brain Res 674 1995 252 259
    • (1995) Brain Res , vol.674 , pp. 252-259
    • Arendash, G.W.1    Sengstock, G.J.2    Sanberg, P.R.3    Kem, W.R.4
  • 56
    • 43149119474 scopus 로고    scopus 로고
    • Comparative effects of the alpha7 nicotinic partial agonist S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice
    • A. Marighetto, S. Valerio, A. Desmedt, J.N. Philippin, C. Trocme-Thibierge, and P. Morain Comparative effects of the alpha7 nicotinic partial agonist S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice Psychopharmacology (Berl) 197 2008 499 508
    • (2008) Psychopharmacology (Berl) , vol.197 , pp. 499-508
    • Marighetto, A.1    Valerio, S.2    Desmedt, A.3    Philippin, J.N.4    Trocme-Thibierge, C.5    Morain, P.6
  • 57
    • 0002100551 scopus 로고    scopus 로고
    • 3-[2,4-dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat α 7 receptors and improves memory-related behaviors in a mecamylamine- sensitive manner
    • DOI 10.1016/S0006-8993(97)00536-2, PII S0006899397005362
    • E.M. Meyer, E.T. Tay, R.L. Papke, C. Meyers, G.L. Huang, and C.M. de Fiebre 3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine- sensitive manner Brain Res 768 1997 49 56 (Pubitemid 27433476)
    • (1997) Brain Research , vol.768 , Issue.1-2 , pp. 49-56
    • Meyer, E.M.1    Tay, E.T.2    Papke, R.L.3    Meyers, C.4    Huang, G.-L.5    De Fiebre, C.M.6
  • 58
    • 67349167960 scopus 로고    scopus 로고
    • Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR 180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia
    • S. Barak, M. Arad, A. De Levie, M.D. Black, G. Griebel, and I. Weiner Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR 180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia Neuropsychopharmacology 34 2009 1753 1763
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1753-1763
    • Barak, S.1    Arad, M.2    De Levie, A.3    Black, M.D.4    Griebel, G.5    Weiner, I.6
  • 59
    • 0030858125 scopus 로고    scopus 로고
    • Functional and anatomical aspects of prefrontal pathology in schizophrenia
    • P.S. Goldman-Rakic, and L.D. Selemon Functional and anatomical aspects of prefrontal pathology in schizophrenia Schizophr Bull 23 1997 437 458 (Pubitemid 27427984)
    • (1997) Schizophrenia Bulletin , vol.23 , Issue.3 , pp. 437-458
    • Qoldman-Rakic, P.S.1    Selemon, L.D.2
  • 60
    • 0033237390 scopus 로고    scopus 로고
    • AR-R17779, an α7 nicotinic agonist, improves learning and memory in rats
    • E.D. Levin, C. Bettegowda, J. Blosser, and J. Gordon AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats Behav Pharmacol 10 1999 675 680 (Pubitemid 30026062)
    • (1999) Behavioural Pharmacology , vol.10 , Issue.6-7 , pp. 675-680
    • Levin, E.D.1    Bettegowda, C.2    Blosser, J.3    Gordon, J.4
  • 61
    • 0035708467 scopus 로고    scopus 로고
    • Ventral hippocampal α7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze
    • DOI 10.1016/S0091-3057(01)00643-8, PII S0091305701006438
    • J.H. Bettany, and E.D. Levin Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze Pharmacol Biochem Behav 70 2001 467 474 (Pubitemid 34131641)
    • (2001) Pharmacology Biochemistry and Behavior , vol.70 , Issue.4 , pp. 467-474
    • Bettany, J.H.1    Levin, E.D.2
  • 62
    • 33645741208 scopus 로고    scopus 로고
    • Dorsal hippocampal alpha7 and alpha4beta2 nicotinic receptors and memory
    • A. Nott, and E.D. Levin Dorsal hippocampal alpha7 and alpha4beta2 nicotinic receptors and memory Brain Res 1081 2006 72 78
    • (2006) Brain Res , vol.1081 , pp. 72-78
    • Nott, A.1    Levin, E.D.2
  • 63
    • 0037154981 scopus 로고    scopus 로고
    • Hippocampal α7 and α4β2 nicotinic receptors and working memory
    • DOI 10.1016/S0306-4522(01)00538-3, PII S0306452201005383
    • E.D. Levin, A. Bradley, N. Addy, and N. Sigurani Hippocampal alpha 7 and alpha 4 beta 2 nicotinic receptors and working memory Neuroscience 109 2002 757 765 (Pubitemid 34260859)
    • (2002) Neuroscience , vol.109 , Issue.4 , pp. 757-765
    • Levin, E.D.1    Bradley, A.2    Addy, N.3    Sigurani, N.4
  • 64
    • 33746870022 scopus 로고    scopus 로고
    • Performance deficit of α7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory
    • DOI 10.1111/j.1601-183X.2005.00176.x
    • C. Fernandes, E. Hoyle, E. Dempster, L.C. Schalkwyk, and D.A. Collier Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory Genes Brain Behav 5 2006 433 440 (Pubitemid 44199563)
    • (2006) Genes, Brain and Behavior , vol.5 , Issue.6 , pp. 433-440
    • Fernandes, C.1    Hoyle, E.2    Dempster, E.3    Schalkwyk, L.C.4    Collier, D.A.5
  • 66
    • 77956247430 scopus 로고    scopus 로고
    • In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: Preclinical considerations in Alzheimer's disease
    • R.S. Bitner, W.H. Bunnelle, M.W. Decker, K.U. Drescher, K.L. Kohlhaas, and S. Markosyan In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease J Pharmacol Exp Ther 334 2010 875 886
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 875-886
    • Bitner, R.S.1    Bunnelle, W.H.2    Decker, M.W.3    Drescher, K.U.4    Kohlhaas, K.L.5    Markosyan, S.6
  • 68
    • 78649994788 scopus 로고    scopus 로고
    • Immediate and sustained improvements in working memory after selective stimulation of alpha7 nicotinic acetylcholine receptors
    • S.A. Castner, G.N. Smagin, T.M. Piser, Y. Wang, J.S. Smith, and E.P. Christian Immediate and sustained improvements in working memory after selective stimulation of alpha7 nicotinic acetylcholine receptors Biol Psychiatry 69 2011 12 18
    • (2011) Biol Psychiatry , vol.69 , pp. 12-18
    • Castner, S.A.1    Smagin, G.N.2    Piser, T.M.3    Wang, Y.4    Smith, J.S.5    Christian, E.P.6
  • 70
    • 33750613621 scopus 로고    scopus 로고
    • Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task
    • DOI 10.1007/s00213-006-0549-2
    • E. Hoyle, R.F. Genn, C. Fernandes, and I.P. Stolerman Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task Psychopharmacology (Berl) 189 2006 211 223 (Pubitemid 44691543)
    • (2006) Psychopharmacology , vol.189 , Issue.2 , pp. 211-223
    • Hoyle, E.1    Genn, R.F.2    Fernandes, C.3    Stolerman, I.P.4
  • 72
    • 0034694951 scopus 로고    scopus 로고
    • Effect of subtype selective nicotinic compounds on attention as assessed by the five-choice serial reaction time task
    • A.J. Grottick, and G.A. Higgins Effect of subtype selective nicotinic compounds on attention as assessed by the five-choice serial reaction time task Behav Brain Res 117 2000 197 208
    • (2000) Behav Brain Res , vol.117 , pp. 197-208
    • Grottick, A.J.1    Higgins, G.A.2
  • 73
    • 0037712944 scopus 로고    scopus 로고
    • Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands
    • A.J. Grottick, M. Haman, R. Wyler, and G.A. Higgins Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands Neuropsychopharmacology 28 2003 880 887
    • (2003) Neuropsychopharmacology , vol.28 , pp. 880-887
    • Grottick, A.J.1    Haman, M.2    Wyler, R.3    Higgins, G.A.4
  • 74
  • 75
    • 0034019113 scopus 로고    scopus 로고
    • Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: Antagonist studies
    • DOI 10.1007/s002130000378
    • A. Blondel, D.J. Sanger, and P.C. Moser Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: antagonist studies Psychopharmacology (Berl) 149 2000 293 305 (Pubitemid 30262344)
    • (2000) Psychopharmacology , vol.149 , Issue.3 , pp. 293-305
    • Blondel, A.1    Sanger, D.J.2    Moser, P.C.3
  • 76
    • 67349209574 scopus 로고    scopus 로고
    • A cog in cognition: How the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits
    • S.C. Leiser, M.R. Bowlby, T.A. Comery, and J. Dunlop A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits Pharmacol Ther 122 2009 302 311
    • (2009) Pharmacol Ther , vol.122 , pp. 302-311
    • Leiser, S.C.1    Bowlby, M.R.2    Comery, T.A.3    Dunlop, J.4
  • 77
    • 3142761435 scopus 로고    scopus 로고
    • Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia
    • L.F. Martin, W.R. Kem, and R. Freedman Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia Psychopharmacology (Berl) 174 2004 54 64 (Pubitemid 38925091)
    • (2004) Psychopharmacology , vol.174 , Issue.1 , pp. 54-64
    • Martin, L.F.1    Kem, W.R.2    Freedman, R.3
  • 78
    • 14344251489 scopus 로고    scopus 로고
    • The selective α7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats
    • DOI 10.1124/jpet.104.076968
    • M. Hajos, R.S. Hurst, W.E. Hoffmann, M. Krause, T.M. Wall, and N.R. Higdon The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats J Pharmacol Exp Ther 312 2005 1213 1222 (Pubitemid 40293783)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.312 , Issue.3 , pp. 1213-1222
    • Hajos, M.1    Hurst, R.S.2    Hoffmann, W.E.3    Krause, M.4    Wall, T.M.5    Higdon, N.R.6    Groppi, V.E.7
  • 79
    • 0034926925 scopus 로고    scopus 로고
    • The DBA/2J strain and prepulse inhibition of startle: A model system to test antipsychotics?
    • DOI 10.1007/s002130100828
    • B. Olivier, C. Leahy, T. Mullen, R. Paylor, V.E. Groppi, and Z. Sarnyai The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics? Psychopharmacology (Berl) 156 2001 284 290 (Pubitemid 32702219)
    • (2001) Psychopharmacology , vol.156 , Issue.2-3 , pp. 284-290
    • Olivier, B.1    Leahy, C.2    Mullen, T.3    Paylor, R.4    Groppi, V.E.5    Sarnyai, Z.6    Brunner, D.7
  • 80
    • 0031596817 scopus 로고    scopus 로고
    • 7-nicotinic agonists normalize inhibition of auditory response in DBA mice
    • DOI 10.1007/s002130050573
    • K.E. Stevens, W.R. Kem, V.M. Mahnir, and R. Freedman Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice Psychopharmacology (Berl) 136 1998 320 327 (Pubitemid 28189660)
    • (1998) Psychopharmacology , vol.136 , Issue.4 , pp. 320-327
    • Stevens, K.E.1    Kem, W.R.2    Mahnir, V.M.3    Freedman, R.4
  • 81
    • 0026664965 scopus 로고
    • Cholinergic gating of response to auditory stimuli in rat hippocampus
    • V. Luntz-Leybman, P.C. Bickford, and R. Freedman Cholinergic gating of response to auditory stimuli in rat hippocampus Brain Res 587 1992 130 136
    • (1992) Brain Res , vol.587 , pp. 130-136
    • Luntz-Leybman, V.1    Bickford, P.C.2    Freedman, R.3
  • 82
    • 0141993546 scopus 로고    scopus 로고
    • 7 nicotinic agonist, normalizes auditory gating in isolation-reared rats
    • DOI 10.1007/s00213-003-1482-2
    • H.C. O'Neill, K. Rieger, W.R. Kem, and K.E. Stevens DMXB, an alpha7 nicotinic agonist, normalizes auditory gating in isolation-reared rats Psychopharmacology (Berl) 169 2003 332 339 (Pubitemid 37255522)
    • (2003) Psychopharmacology , vol.169 , Issue.3-4 , pp. 332-339
    • O'Neill, H.C.1    Rieger, K.2    Kem, W.R.3    Stevens, K.E.4
  • 83
    • 0036170063 scopus 로고    scopus 로고
    • 7-nicotine acetylcholine receptor agonists on prepulse inhibition of the acoustic startle response in rats and mice
    • DOI 10.1007/s00213-001-0927-8
    • R. Schreiber, M. Dalmus, and J. De Vry Effects of alpha 4/beta 2- and alpha 7-nicotine acetylcholine receptor agonists on prepulse inhibition of the acoustic startle response in rats and mice Psychopharmacology (Berl) 159 2002 248 257 (Pubitemid 34143373)
    • (2002) Psychopharmacology , vol.159 , Issue.3 , pp. 248-257
    • Schreiber, R.1    Dalmus, M.2    De Vry, J.3
  • 84
    • 0033377797 scopus 로고    scopus 로고
    • Sensory gating in rats: Lack of correlation between auditory evoked potential gating and prepulse inhibition
    • B.A. Ellenbroek, G. van Luijtelaar, M. Frenken, and A.R. Cools Sensory gating in rats: lack of correlation between auditory evoked potential gating and prepulse inhibition Schizophr Bull 25 1999 777 788 (Pubitemid 30013559)
    • (1999) Schizophrenia Bulletin , vol.25 , Issue.4 , pp. 777-788
    • Ellenbroek, B.A.1    Van Luijtelaar, G.2    Frenken, M.3    Cools, A.R.4
  • 85
    • 20444463577 scopus 로고    scopus 로고
    • A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors
    • DOI 10.1016/j.schres.2005.02.010, PII S0920996405000757
    • J. de Leon, and F.J. Diaz A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors Schizophr Res 76 2005 135 157 (Pubitemid 40812332)
    • (2005) Schizophrenia Research , vol.76 , Issue.2-3 , pp. 135-157
    • De Leon, J.1    Diaz, F.J.2
  • 86
    • 67651091553 scopus 로고    scopus 로고
    • Prefrontal cognitive dysfunction is associated with tobacco dependence treatment failure in smokers with schizophrenia
    • T.G. Moss, K.A. Sacco, T.M. Allen, A.H. Weinberger, J.C. Vessicchio, and T.P. George Prefrontal cognitive dysfunction is associated with tobacco dependence treatment failure in smokers with schizophrenia Drug Alcohol Depend 104 2009 94 99
    • (2009) Drug Alcohol Depend , vol.104 , pp. 94-99
    • Moss, T.G.1    Sacco, K.A.2    Allen, T.M.3    Weinberger, A.H.4    Vessicchio, J.C.5    George, T.P.6
  • 89
    • 78751507926 scopus 로고    scopus 로고
    • Characterization of 2-[[4-fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4- pyridinyl)-5-thiazoleme thanol (JNJ-1930942), a novel positive allosteric modulator of the {alpha}7 nicotinic acetylcholine receptor
    • T. Dinklo, H. Shaban, J.W. Thuring, H. Lavreysen, K.E. Stevens, and L. Zheng Characterization of 2-[[4-fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4- pyridinyl)-5-thiazoleme thanol (JNJ-1930942), a novel positive allosteric modulator of the {alpha}7 nicotinic acetylcholine receptor J Pharmacol Exp Ther 336 2011 560 574
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 560-574
    • Dinklo, T.1    Shaban, H.2    Thuring, J.W.3    Lavreysen, H.4    Stevens, K.E.5    Zheng, L.6
  • 90
    • 62449113374 scopus 로고    scopus 로고
    • Old and new pharmacology: Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5- b′]di pyrrole-1(2H)-carboxamide)
    • J. Dunlop, T. Lock, B. Jow, F. Sitzia, S. Grauer, and F. Jow Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b′]di pyrrole-1(2H)-carboxamide) J Pharmacol Exp Ther 328 2009 766 776
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 766-776
    • Dunlop, J.1    Lock, T.2    Jow, B.3    Sitzia, F.4    Grauer, S.5    Jow, F.6
  • 93
    • 32844461888 scopus 로고    scopus 로고
    • Nicotinic effects on cognitive function: Behavioral characterization, pharmacological specification, and anatomic localization
    • DOI 10.1007/s00213-005-0164-7
    • E.D. Levin, F.J. McClernon, and A.H. Rezvani Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization Psychopharmacology (Berl) 184 2006 523 539 (Pubitemid 43255869)
    • (2006) Psychopharmacology , vol.184 , Issue.3-4 , pp. 523-539
    • Levin, E.D.1    McClernon, F.J.2    Rezvani, A.H.3
  • 94
    • 0033626286 scopus 로고    scopus 로고
    • The brain α7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: Studies with DMXBA (GTS-21)
    • DOI 10.1016/S0166-4328(00)00211-4, PII S0166432800002114
    • W.R. Kem The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21) Behav Brain Res 113 2000 169 181 (Pubitemid 30645554)
    • (2000) Behavioural Brain Research , vol.113 , Issue.1-2 , pp. 169-181
    • Kem, W.R.1
  • 96
    • 33645319504 scopus 로고    scopus 로고
    • Targeting the alpha 7 nicotinic acetylcholine receptor to reduce amyloid accumulation in Alzheimer's disease pyramidal neurons
    • M.R. D'Andrea, and R.G. Nagele Targeting the alpha 7 nicotinic acetylcholine receptor to reduce amyloid accumulation in Alzheimer's disease pyramidal neurons Curr Pharm Des 12 2006 677 684
    • (2006) Curr Pharm des , vol.12 , pp. 677-684
    • D'Andrea, M.R.1    Nagele, R.G.2
  • 97
    • 33744726880 scopus 로고    scopus 로고
    • Selective α7 nicotinic acetylcholine receptor ligands
    • DOI 10.2174/092986706777442011
    • A. Mazurov, T. Hauser, and C.H. Miller Selective alpha7 nicotinic acetylcholine receptor ligands Curr Med Chem 13 2006 1567 1584 (Pubitemid 43821705)
    • (2006) Current Medicinal Chemistry , vol.13 , Issue.13 , pp. 1567-1584
    • Mazurov, A.1    Hauser, T.2    Miller, C.H.3
  • 98
    • 0033983966 scopus 로고    scopus 로고
    • Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
    • DOI 10.1046/j.1471-4159.2000.0740237.x
    • Z.Z. Guan, X. Zhang, R. Ravid, and A. Nordberg Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease J Neurochem 74 2000 237 243 (Pubitemid 30012774)
    • (2000) Journal of Neurochemistry , vol.74 , Issue.1 , pp. 237-243
    • Guan, Z.-Z.1    Zhang, X.2    Ravid, R.3    Nordberg, A.4
  • 99
    • 33847250946 scopus 로고    scopus 로고
    • 11C-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease
    • DOI 10.1007/s00213-006-0447-7
    • A. Kadir, O. Almkvist, A. Wall, B. Langstrom, and A. Nordberg PET imaging of cortical 11C-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease Psychopharmacology (Berl) 188 2006 509 520 (Pubitemid 46758966)
    • (2006) Psychopharmacology , vol.188 , Issue.4 , pp. 509-520
    • Kadir, A.1    Almkvist, O.2    Wall, A.3    Langstrom, B.4    Nordberg, A.5
  • 100
  • 102
    • 0037381479 scopus 로고    scopus 로고
    • 1-42
    • DOI 10.1002/neu.10203
    • D.H. Lee, and H.Y. Wang Differential physiologic responses of alpha7 nicotinic acetylcholine receptors to beta-amyloid1-40 and beta-amyloid1-42 J Neurobiol 55 2003 25 30 (Pubitemid 36396959)
    • (2003) Journal of Neurobiology , vol.55 , Issue.1 , pp. 25-30
    • Lee, D.H.S.1    Wang, H.-Y.2
  • 103
    • 0035875962 scopus 로고    scopus 로고
    • β-Amyloid activates the mitogen-activated protein kinase cascade via hippocampal α7 nicotinic acetylcholine receptors: In Vitro and in Vivo mechanisms related to Alzheimer's disease
    • K.T. Dineley, M. Westerman, D. Bui, K. Bell, K.H. Ashe, and J.D. Sweatt Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease J Neurosci 21 2001 4125 4133 (Pubitemid 32538537)
    • (2001) Journal of Neuroscience , vol.21 , Issue.12 , pp. 4125-4133
    • Dineley, K.T.1    Westerman, M.2    Bui, D.3    Bell, K.4    Ashe, K.H.5    Sweatt, J.D.6
  • 104
    • 0043135255 scopus 로고    scopus 로고
    • β-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex
    • J.J. Dougherty, J. Wu, and R.A. Nichols Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex J Neurosci 23 2003 6740 6747 (Pubitemid 36951200)
    • (2003) Journal of Neuroscience , vol.23 , Issue.17 , pp. 6740-6747
    • Dougherty, J.J.1    Wu, J.2    Nichols, R.A.3
  • 106
    • 0034006944 scopus 로고    scopus 로고
    • 1-42 binds to α7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology
    • DOI 10.1074/jbc.275.8.5626
    • H.Y. Wang, D.H. Lee, M.R. D'Andrea, P.A. Peterson, R.P. Shank, and A.B. Reitz beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology J Biol Chem 275 2000 5626 5632 (Pubitemid 30115201)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.8 , pp. 5626-5632
    • Wang, H.-Y.1    Lee, D.H.S.2    D'Andrea, M.R.3    Peterson, P.A.4    Shank, R.P.5    Reitz, A.B.6
  • 107
    • 0033624509 scopus 로고    scopus 로고
    • 1-42 binds selectively and with picomolar affinity to α7 nicotinic acetylcholine receptors
    • DOI 10.1046/j.1471-4159.2000.0751155.x
    • H.Y. Wang, D.H. Lee, C.B. Davis, and R.P. Shank Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors J Neurochem 75 2000 1155 1161 (Pubitemid 30660505)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.3 , pp. 1155-1161
    • Wang, H.-Y.1    Lee, D.H.S.2    Davis, C.B.3    Shank, R.P.4
  • 108
    • 67650484613 scopus 로고    scopus 로고
    • Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease
    • G. Dziewczapolski, C.M. Glogowski, E. Masliah, and S.F. Heinemann Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease J Neurosci 29 2009 8805 8815
    • (2009) J Neurosci , vol.29 , pp. 8805-8815
    • Dziewczapolski, G.1    Glogowski, C.M.2    Masliah, E.3    Heinemann, S.F.4
  • 109
    • 63849213473 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor signalling: Roles in Alzheimer's disease and amyloid neuroprotection
    • S.D. Buckingham, A.K. Jones, L.A. Brown, and D.B. Sattelle Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection Pharmacol Rev 61 2009 39 61
    • (2009) Pharmacol Rev , vol.61 , pp. 39-61
    • Buckingham, S.D.1    Jones, A.K.2    Brown, L.A.3    Sattelle, D.B.4
  • 110
    • 0035957946 scopus 로고    scopus 로고
    • Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
    • T. Kihara, S. Shimohama, H. Sawada, K. Honda, T. Nakamizo, and H. Shibasaki alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity J Biol Chem 276 2001 13541 13546
    • (2001) J Biol Chem , vol.276 , pp. 13541-13546
    • Kihara, T.1    Shimohama, S.2    Sawada, H.3    Honda, K.4    Nakamizo, T.5    Shibasaki, H.6
  • 111
    • 33846029827 scopus 로고    scopus 로고
    • Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model
    • DOI 10.1096/fj.06-5841com
    • Q. Liu, J. Zhang, H. Zhu, C. Qin, Q. Chen, and B. Zhao Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model FASEB J 21 2007 61 73 (Pubitemid 46052545)
    • (2007) FASEB Journal , vol.21 , Issue.1 , pp. 61-73
    • Liu, Q.1    Zhang, J.2    Zhu, H.3    Qin, C.4    Chen, Q.5    Zhao, B.6
  • 112
    • 0032498950 scopus 로고    scopus 로고
    • Neuroprotective effects of 2,4-dimethoxybenzylidene anabaseine (DMXB) and tetrahydroaminoacridine (THA) in neocortices of nucleus basalis lesioned rats
    • DOI 10.1016/S0006-8993(97)00300-4, PII S0006899397003004
    • E.M. Meyer, M.A. King, and C. Meyers Neuroprotective effects of 2,4-dimethoxybenzylidene anabaseine (DMXB) and tetrahydroaminoacridine (THA) in neocortices of nucleus basalis lesioned rats Brain Res 786 1998 252 254 (Pubitemid 28191740)
    • (1998) Brain Research , vol.786 , Issue.1-2 , pp. 252-254
    • Meyer, E.M.1    King, M.A.2    Meyers, C.3
  • 113
    • 77952360311 scopus 로고    scopus 로고
    • DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-)) injected mice through preventing the dysfunction of alpha7 nicotinic receptor
    • L. Chen, H. Wang, Z. Zhang, Z. Li, D. He, and M. Sokabe DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-)) injected mice through preventing the dysfunction of alpha7 nicotinic receptor J Neurosci Res 88 2010 1784 1794
    • (2010) J Neurosci Res , vol.88 , pp. 1784-1794
    • Chen, L.1    Wang, H.2    Zhang, Z.3    Li, Z.4    He, D.5    Sokabe, M.6
  • 114
    • 62949084265 scopus 로고    scopus 로고
    • Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo
    • R.S. Bitner, A.L. Nikkel, S. Markosyan, S. Otte, P. Puttfarcken, and M. Gopalakrishnan Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo Brain Res 1265 2009 65 74
    • (2009) Brain Res , vol.1265 , pp. 65-74
    • Bitner, R.S.1    Nikkel, A.L.2    Markosyan, S.3    Otte, S.4    Puttfarcken, P.5    Gopalakrishnan, M.6
  • 115
    • 80052023127 scopus 로고    scopus 로고
    • EVP-6124 safety, tolerability and cognitive effects of a novel alpha7 nicotinic receptor agonist in Alzheimer's disease patients on stable donepezil or rivastigmine therapy
    • Vienna, Austria
    • D. Hilt, B. Safirstein, D. Hassman, J. Apter, S. Thein, and P. Maruff EVP-6124 safety, tolerability and cognitive effects of a novel alpha7 nicotinic receptor agonist in Alzheimer's disease patients on stable donepezil or rivastigmine therapy International Congress on Alzheimer's Disease Vienna, Austria 2009
    • (2009) International Congress on Alzheimer's Disease
    • Hilt, D.1    Safirstein, B.2    Hassman, D.3    Apter, J.4    Thein, S.5    Maruff, P.6
  • 118
    • 34548321168 scopus 로고    scopus 로고
    • Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia
    • DOI 10.1093/schbul/sbm083
    • R.W. Buchanan, R. Freedman, D.C. Javitt, A. Abi-Dargham, and J.A. Lieberman Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia Schizophr Bull 33 2007 1120 1130 (Pubitemid 47347922)
    • (2007) Schizophrenia Bulletin , vol.33 , Issue.5 , pp. 1120-1130
    • Buchanan, R.W.1    Freedman, R.2    Javitt, D.C.3    Abi-Dargham, A.4    Lieberman, J.A.5
  • 119
    • 0030297344 scopus 로고    scopus 로고
    • Nicotine-haloperidol interactions and cognitive performance in schizophrenics
    • DOI 10.1016/S0893-133X(96)00018-8, PII S0893133X9600018X
    • E.D. Levin, W. Wilson, J.E. Rose, and J. McEvoy Nicotine-haloperidol interactions and cognitive performance in schizophrenics Neuropsychopharmacology 15 1996 429 436 (Pubitemid 26389866)
    • (1996) Neuropsychopharmacology , vol.15 , Issue.5 , pp. 429-436
    • Levin, E.D.1    Wilson, W.2    Rose, J.E.3    McEvoy, J.4
  • 120
    • 0027380988 scopus 로고
    • Normalization of auditory physiology by cigarette smoking in schizophrenic patients
    • L.E. Adler, L.D. Hoffer, A. Wiser, and R. Freedman Normalization of auditory physiology by cigarette smoking in schizophrenic patients Am J Psychiatry 150 1993 1856 1861 (Pubitemid 23356580)
    • (1993) American Journal of Psychiatry , vol.150 , Issue.12 , pp. 1856-1861
    • Adler, L.E.1    Hoffer, L.D.2    Wiser, A.3    Freedman, R.4
  • 121
    • 0029085870 scopus 로고
    • Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
    • R. Freedman, M. Hall, L.E. Adler, and S. Leonard Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia Biol Psychiatry 38 1995 22 33
    • (1995) Biol Psychiatry , vol.38 , pp. 22-33
    • Freedman, R.1    Hall, M.2    Adler, L.E.3    Leonard, S.4
  • 127
  • 131
    • 80052024271 scopus 로고    scopus 로고
    • The alpha7 neuronal nicotinic receptor (NNR) agonist TC-5619 had beneficial effects and was generally well tolerated in a phase 2 trial in cognitive dysfunction in schizophrenia (CDS)
    • Colorado Springs, Colorado, USA
    • D. Hosford, G. Dunbar, J.A. Lieberman, and A. Segreti The alpha7 neuronal nicotinic receptor (NNR) agonist TC-5619 had beneficial effects and was generally well tolerated in a phase 2 trial in cognitive dysfunction in schizophrenia (CDS) 13th international congress on schizophrenia research Colorado Springs, Colorado, USA 2011
    • (2011) 13th International Congress on Schizophrenia Research
    • Hosford, D.1    Dunbar, G.2    Lieberman, J.A.3    Segreti, A.4
  • 132
    • 0004235298 scopus 로고
    • A.P. Association 4th ed. American Psychiatric Association Washington, DC
    • A.P. Association Diagnostic and statistical manual of mental disorders 4th ed. 1994 American Psychiatric Association Washington, DC
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 133
    • 0031928549 scopus 로고    scopus 로고
    • Nicotinic acetylcholine involvement in cogitive function in animals
    • DOI 10.1007/s002130050667
    • E.D. Levin, and B.B. Simon Nicotinic acetylcholine involvement in cognitive function in animals Psychopharmacology (Berl) 138 1998 217 230 (Pubitemid 28365487)
    • (1998) Psychopharmacology , vol.138 , Issue.3-4 , pp. 217-230
    • Levin, E.D.1    Simon, B.B.2
  • 135
    • 0030737908 scopus 로고    scopus 로고
    • Further evidence of an association between attention- deficit/hyperactivity disorder and cigarette smoking: Findings from a high- risk sample of siblings
    • S. Milberger, J. Biederman, S.V. Faraone, L. Chen, and J. Jones Further evidence of an association between attention-deficit/hyperactivity disorder and cigarette smoking Findings from a high-risk sample of siblings Am J Addict 6 1997 205 217 (Pubitemid 27356003)
    • (1997) American Journal on Addictions , vol.6 , Issue.3 , pp. 205-217
    • Milberger, S.1    Biederman, J.2    Faraone, S.V.3    Chen, L.4    Jones, J.5
  • 136
    • 0029767702 scopus 로고    scopus 로고
    • Is maternal smoking during pregnancy a risk factor for attention deficit hyperactivity disorder in children?
    • S. Milberger, J. Biederman, S.V. Faraone, L. Chen, and J. Jones Is maternal smoking during pregnancy a risk factor for attention deficit hyperactivity disorder in children? Am J Psychiatry 153 1996 1138 1142 (Pubitemid 26299831)
    • (1996) American Journal of Psychiatry , vol.153 , Issue.9 , pp. 1138-1142
    • Milberger, S.1    Biederman, J.2    Faraone, S.V.3    Chen, L.4    Jones, J.5
  • 139
    • 77953150437 scopus 로고    scopus 로고
    • Cholinergic abnormalities in autism: Is there a rationale for selective nicotinic agonist interventions?
    • S.I. Deutsch, M.R. Urbano, S.R. Neumann, J.A. Burket, and E. Katz Cholinergic abnormalities in autism: is there a rationale for selective nicotinic agonist interventions? Clin Neuropharmacol 33 2010 114 120
    • (2010) Clin Neuropharmacol , vol.33 , pp. 114-120
    • Deutsch, S.I.1    Urbano, M.R.2    Neumann, S.R.3    Burket, J.A.4    Katz, E.5
  • 143
  • 144
    • 34548683244 scopus 로고    scopus 로고
    • Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys
    • DOI 10.1016/j.bcp.2007.07.010, PII S0006295207004625
    • J.J. Buccafusco, A.V. Terry Jr., M.W. Decker, and M. Gopalakrishnan Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys Biochem Pharmacol 74 2007 1202 1211 (Pubitemid 47417930)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.8 , pp. 1202-1211
    • Buccafusco, J.J.1    Terry Jr., A.V.2    Decker, M.W.3    Gopalakrishnan, M.4
  • 145
    • 57349165705 scopus 로고    scopus 로고
    • Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice
    • J.P. Redrobe, E.O. Nielsen, J.K. Christensen, D. Peters, D.B. Timmermann, and G.M. Olsen Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice Eur J Pharmacol 602 2009 58 65
    • (2009) Eur J Pharmacol , vol.602 , pp. 58-65
    • Redrobe, J.P.1    Nielsen, E.O.2    Christensen, J.K.3    Peters, D.4    Timmermann, D.B.5    Olsen, G.M.6
  • 148
    • 53949092571 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and modulation of learning in 4- and 27-month-old rabbits
    • J.G. Li, M. Lehr, L.Y. Liu-Chen, and D.S. Woodruff-Pak Nicotinic acetylcholine receptors and modulation of learning in 4- and 27-month-old rabbits Neuropsychopharmacology 33 2008 2820 2830
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2820-2830
    • Li, J.G.1    Lehr, M.2    Liu-Chen, L.Y.3    Woodruff-Pak, D.S.4
  • 149
    • 68349141525 scopus 로고    scopus 로고
    • Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes
    • S. Sydserff, E.J. Sutton, D. Song, M.C. Quirk, C. Maciag, and C. Li Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes Biochem Pharmacol 78 2009 880 888
    • (2009) Biochem Pharmacol , vol.78 , pp. 880-888
    • Sydserff, S.1    Sutton, E.J.2    Song, D.3    Quirk, M.C.4    MacIag, C.5    Li, C.6
  • 151
    • 0028199608 scopus 로고
    • A nicotinic agonist (GTS-21), eyeblink classical conditioning, and nicotinic receptor binding in rabbit brain
    • D.S. Woodruff-Pak, Y.T. Li, and W.R. Kem A nicotinic agonist (GTS-21), eyeblink classical conditioning, and nicotinic receptor binding in rabbit brain Brain Res 645 1994 309 317 (Pubitemid 24140138)
    • (1994) Brain Research , vol.645 , Issue.1-2 , pp. 309-317
    • Woodruff-Pak, D.S.1    Li, Y.-T.2    Kem, W.R.3
  • 152
    • 0033736632 scopus 로고    scopus 로고
    • A nicotinic cholinergic agonist (GTS-21) and eyeblink classical conditioning: Acquisition, retention, and relearning in older rabbits
    • D.S. Woodruff-Pak, J.T. Green, C. Coleman-Valencia, and J.T. Pak A nicotinic cholinergic agonist (GTS-21) and eyeblink classical conditioning: acquisition, retention, and relearning in older rabbits Exp Aging Res 26 2000 323 336
    • (2000) Exp Aging Res , vol.26 , pp. 323-336
    • Woodruff-Pak, D.S.1    Green, J.T.2    Coleman-Valencia, C.3    Pak, J.T.4
  • 153
    • 0042594579 scopus 로고    scopus 로고
    • Mecamylamine reversal by nicotine and by a partial α7 nicotinic acetylcholine receptor agonist (GTS-21) in rabbits tested with delay eyeblink classical conditioning
    • DOI 10.1016/S0166-4328(03)00039-1
    • D.S. Woodruff-Pak Mecamylamine reversal by nicotine and by a partial alpha7 nicotinic acetylcholine receptor agonist (GTS-21) in rabbits tested with delay eyeblink classical conditioning Behav Brain Res 143 2003 159 167 (Pubitemid 36937161)
    • (2003) Behavioural Brain Research , vol.143 , Issue.2 , pp. 159-167
    • Woodruff-Pak, D.S.1
  • 154
    • 0028883095 scopus 로고
    • Diversity of neuronal nicotinic acetylcholine receptors: Lessons from behavior and implications for CNS therapeutics
    • M.W. Decker, J.D. Brioni, A.W. Bannon, and S.P. Arneric Diversity of neuronal nicotinic acetylcholine receptors: lessons from behavior and implications for CNS therapeutics Life Sci 56 1995 545 570
    • (1995) Life Sci , vol.56 , pp. 545-570
    • Decker, M.W.1    Brioni, J.D.2    Bannon, A.W.3    Arneric, S.P.4
  • 155
    • 0035470834 scopus 로고    scopus 로고
    • Intragastric DMXB-A, an α7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice
    • DOI 10.1016/S0006-3223(01)01093-9, PII S0006322301010939
    • J.K. Simosky, K.E. Stevens, W.R. Kem, and R. Freedman Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice Biol Psychiatry 50 2001 493 500 (Pubitemid 32971880)
    • (2001) Biological Psychiatry , vol.50 , Issue.7 , pp. 493-500
    • Simosky, J.K.1    Stevens, K.E.2    Kem, W.R.3    Freedman, R.4
  • 156
    • 0032753990 scopus 로고    scopus 로고
    • Selective alpha 7 nicotinic receptor stimulation normalizes chronic cocaine-induced loss of hippocampal sensory inhibition in C3H mice
    • K.E. Stevens, W.R. Kem, and R. Freedman Selective alpha 7 nicotinic receptor stimulation normalizes chronic cocaine-induced loss of hippocampal sensory inhibition in C3H mice Biol Psychiatry 46 1999 1443 1450
    • (1999) Biol Psychiatry , vol.46 , pp. 1443-1450
    • Stevens, K.E.1    Kem, W.R.2    Freedman, R.3
  • 157
    • 58049109125 scopus 로고    scopus 로고
    • The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain
    • D. Feuerbach, K. Lingenhoehl, H.R. Olpe, A. Vassout, C. Gentsch, and F. Chaperon The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain Neuropharmacology 56 2009 254 263
    • (2009) Neuropharmacology , vol.56 , pp. 254-263
    • Feuerbach, D.1    Lingenhoehl, K.2    Olpe, H.R.3    Vassout, A.4    Gentsch, C.5    Chaperon, F.6
  • 161
    • 34249745752 scopus 로고    scopus 로고
    • Frontal cortical α7 and α4β2 nicotinic acetylcholine receptors in working and reference memory
    • DOI 10.1016/j.neuropharm.2007.03.008, PII S0028390807000767
    • W.K. Chan, P.T. Wong, and F.S. Sheu Frontal cortical alpha7 and alpha4beta2 nicotinic acetylcholine receptors in working and reference memory Neuropharmacology 52 2007 1641 1649 (Pubitemid 46843139)
    • (2007) Neuropharmacology , vol.52 , Issue.8 , pp. 1641-1649
    • Chan, W.K.1    Tsun-Hon Wong, P.2    Sheu, F.-S.3
  • 163
  • 164
    • 36849055179 scopus 로고    scopus 로고
    • Phencyclidine-Induced Cognitive Deficits in Mice Are Improved by Subsequent Subchronic Administration of the Novel Selective α7 Nicotinic Receptor Agonist SSR180711
    • DOI 10.1016/j.biopsych.2007.04.034, PII S0006322307004246, Schizophrenia: From Genetics to Treatment
    • K. Hashimoto, T. Ishima, Y. Fujita, M. Matsuo, T. Kobashi, and M. Takahagi Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective alpha7 nicotinic receptor agonist SSR 180711 Biol Psychiatry 63 2008 92 97 (Pubitemid 350234890)
    • (2008) Biological Psychiatry , vol.63 , Issue.1 , pp. 92-97
    • Hashimoto, K.1    Ishima, T.2    Fujita, Y.3    Matsuo, M.4    Kobashi, T.5    Takahagi, M.6    Tsukada, H.7    Iyo, M.8
  • 165
    • 67349085106 scopus 로고    scopus 로고
    • Alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment
    • M.S. Thomsen, D.Z. Christensen, H.H. Hansen, J.P. Redrobe, and J.D. Mikkelsen alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment Neuropharmacology 56 2009 1001 1009
    • (2009) Neuropharmacology , vol.56 , pp. 1001-1009
    • Thomsen, M.S.1    Christensen, D.Z.2    Hansen, H.H.3    Redrobe, J.P.4    Mikkelsen, J.D.5
  • 166
    • 68349148342 scopus 로고    scopus 로고
    • TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia
    • T.A. Hauser, A. Kucinski, K.G. Jordan, G.J. Gatto, S.R. Wersinger, and R.A. Hesse TC-5619: an alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia Biochem Pharmacol 78 2009 803 812
    • (2009) Biochem Pharmacol , vol.78 , pp. 803-812
    • Hauser, T.A.1    Kucinski, A.2    Jordan, K.G.3    Gatto, G.J.4    Wersinger, S.R.5    Hesse, R.A.6
  • 167
    • 66349096318 scopus 로고    scopus 로고
    • Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl) benzenesulfonami de (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor
    • R. Faghih, S.M. Gopalakrishnan, J.H. Gronlien, J. Malysz, C.A. Briggs, and C. Wetterstrand Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H- pyrrol-1-yl)benzenesulfonami de (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor J Med Chem 52 2009 3377 3384
    • (2009) J Med Chem , vol.52 , pp. 3377-3384
    • Faghih, R.1    Gopalakrishnan, S.M.2    Gronlien, J.H.3    Malysz, J.4    Briggs, C.A.5    Wetterstrand, C.6
  • 168
    • 26844530147 scopus 로고    scopus 로고
    • Reversal of isolation-rearing-induced PPI deficits by an α7 nicotinic receptor agonist
    • DOI 10.1007/s00213-005-0069-5
    • J. Cilia, J.E. Cluderay, M.J. Robbins, C. Reavill, E. Southam, and J.N. Kew Reversal of isolation-rearing-induced PPI deficits by an alpha7 nicotinic receptor agonist Psychopharmacology (Berl) 182 2005 214 219 (Pubitemid 41464614)
    • (2005) Psychopharmacology , vol.182 , Issue.2 , pp. 214-219
    • Cilia, J.1    Cluderay, J.E.2    Robbins, M.J.3    Reavill, C.4    Southam, E.5    Kew, J.N.C.6    Jones, D.N.C.7


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