-
1
-
-
35348967477
-
Relevance of donepezil in enhancing learning and memory in special populations: A review of the literature
-
DOI 10.1007/s10803-006-0322-8
-
J.H. Yoo, M.G. Valdovinos, and D.C. Williams Relevance of donepezil in enhancing learning and memory in special populations: a review of the literature J Autism Dev Disord 37 2007 1883 1901 (Pubitemid 47609347)
-
(2007)
Journal of Autism and Developmental Disorders
, vol.37
, Issue.10
, pp. 1883-1901
-
-
Yoo, J.H.1
Valdovinos, M.G.2
Williams, D.C.3
-
2
-
-
47749150634
-
A systematic review of off-label uses of memantine for psychiatric disorders
-
DOI 10.1016/j.pnpbp.2008.01.008, PII S0278584608000237
-
K. Zdanys, and R.R. Tampi A systematic review of off-label uses of memantine for psychiatric disorders Prog Neuropsychopharmacol Biol Psychiatry 32 2008 1362 1374 (Pubitemid 352033662)
-
(2008)
Progress in Neuro-Psychopharmacology and Biological Psychiatry
, vol.32
, Issue.6
, pp. 1362-1374
-
-
Zdanys, K.1
Tampi, R.R.2
-
3
-
-
77949771090
-
Cholinesterase inhibitors as adjunctive therapy in patients with schizophrenia and schizoaffective disorder: A review and meta-analysis of the literature
-
S.R. Ribeiz, D.P. Bassitt, J.A. Arrais, R. Avila, D.C. Steffens, and C.M. Bottino Cholinesterase inhibitors as adjunctive therapy in patients with schizophrenia and schizoaffective disorder: a review and meta-analysis of the literature CNS Drugs 24 2010 303 317
-
(2010)
CNS Drugs
, vol.24
, pp. 303-317
-
-
Ribeiz, S.R.1
Bassitt, D.P.2
Arrais, J.A.3
Avila, R.4
Steffens, D.C.5
Bottino, C.M.6
-
4
-
-
0035251680
-
Cognitive effects of nicotine
-
DOI 10.1016/S0006-3223(00)01094-5, PII S0006322300010945
-
A.H. Rezvani, and E.D. Levin Cognitive effects of nicotine Biol Psychiatry 49 2001 258 267 (Pubitemid 32178435)
-
(2001)
Biological Psychiatry
, vol.49
, Issue.3
, pp. 258-267
-
-
Rezvani, A.H.1
Levin, E.D.2
-
6
-
-
33747422892
-
Brain nicotinic acetylcholine receptors: native subtypes and their relevance
-
DOI 10.1016/j.tips.2006.07.004, PII S0165614706001751
-
C. Gotti, M. Zoli, and F. Clementi Brain nicotinic acetylcholine receptors: native subtypes and their relevance Trends Pharmacol Sci 27 2006 482 491 (Pubitemid 44251225)
-
(2006)
Trends in Pharmacological Sciences
, vol.27
, Issue.9
, pp. 482-491
-
-
Gotti, C.1
Zoli, M.2
Clementi, F.3
-
7
-
-
33847029091
-
Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
-
J.A. Dani, and D. Bertrand Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system Annu Rev Pharmacol Toxicol 47 2007 699 729
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 699-729
-
-
Dani, J.A.1
Bertrand, D.2
-
8
-
-
69949159308
-
Nicotinic receptors: Allosteric transitions and therapeutic targets in the nervous system
-
A. Taly, P.J. Corringer, D. Guedin, P. Lestage, and J.P. Changeux Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system Nat Rev Drug Discov 8 2009 733 750
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 733-750
-
-
Taly, A.1
Corringer, P.J.2
Guedin, D.3
Lestage, P.4
Changeux, J.P.5
-
9
-
-
34548677767
-
Allosteric modulation of nicotinic acetylcholine receptors
-
DOI 10.1016/j.bcp.2007.07.011, PII S0006295207004637
-
D. Bertrand, and M. Gopalakrishnan Allosteric modulation of nicotinic acetylcholine receptors Biochem Pharmacol 74 2007 1155 1163 (Pubitemid 47417931)
-
(2007)
Biochemical Pharmacology
, vol.74
, Issue.8
, pp. 1155-1163
-
-
Bertrand, D.1
Gopalakrishnan, M.2
-
10
-
-
0022972567
-
α-Bungarotoxin binds to low-affinity nicotine binding sites in rat brain
-
DOI 10.1111/j.1471-4159.1986.tb13078.x
-
S. Wonnacott alpha-Bungarotoxin binds to low-affinity nicotine binding sites in rat brain J Neurochem 47 1986 1706 1712 (Pubitemid 17191481)
-
(1986)
Journal of Neurochemistry
, vol.47
, Issue.6
, pp. 1706-1712
-
-
Wonnacott, S.1
-
11
-
-
0038771243
-
Co-expression of α7 and β2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons
-
DOI 10.1016/S0306-4522(03)00220-3
-
L. Azam, U. Winzer-Serhan, and F.M. Leslie Co-expression of alpha7 and beta2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons Neuroscience 119 2003 965 977 (Pubitemid 36776447)
-
(2003)
Neuroscience
, vol.119
, Issue.4
, pp. 965-977
-
-
Azam, L.1
Winzer-Serhan, U.2
Leslie, F.M.3
-
12
-
-
59649090731
-
A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides
-
Q. Liu, Y. Huang, F. Xue, A. Simard, J. DeChon, and G. Li A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides J Neurosci 29 2009 918 929
-
(2009)
J Neurosci
, vol.29
, pp. 918-929
-
-
Liu, Q.1
Huang, Y.2
Xue, F.3
Simard, A.4
Dechon, J.5
Li, G.6
-
13
-
-
0021909380
-
125I]- α-bungarotoxin
-
P.B. Clarke, R.D. Schwartz, S.M. Paul, C.B. Pert, and A. Pert Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine [3H]nicotine, and [125I]-alpha-bungarotoxin J Neurosci 5 1985 1307 1315 (Pubitemid 15098442)
-
(1985)
Journal of Neuroscience
, vol.5
, Issue.5
, pp. 1307-1315
-
-
Clarke, P.B.S.1
Schwartz, R.D.2
Paul, S.M.3
-
14
-
-
0027518923
-
7: A nicotinic cation channel highly permeable to calcium
-
P. Seguela, J. Wadiche, K. Dineley-Miller, J.A. Dani, and J.W. Patrick Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium J Neurosci 13 1993 596 604 (Pubitemid 23045143)
-
(1993)
Journal of Neuroscience
, vol.13
, Issue.2
, pp. 596-604
-
-
Seguela, P.1
Wadiche, J.2
Dineley-Miller, K.3
Dani, J.A.4
Patrick, J.W.5
-
15
-
-
1242272110
-
Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: An autoradiographic study in the rat brain
-
DOI 10.1016/j.neuroscience.2003.09.028
-
E. Tribollet, D. Bertrand, A. Marguerat, and M. Raggenbass Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain Neuroscience 124 2004 405 420 (Pubitemid 38229660)
-
(2004)
Neuroscience
, vol.124
, Issue.2
, pp. 405-420
-
-
Tribollet, E.1
Bertrand, D.2
Marguerat, A.3
Raggenbass, M.4
-
16
-
-
0026475948
-
Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: Localization of alpha 3 subunit mRNA, alpha-bungarotoxin and nicotine binding sites
-
M. Cimino, P. Marini, D. Fornasari, F. Cattabeni, and F. Clementi Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: localization of alpha 3 subunit mRNA, alpha-bungarotoxin and nicotine binding sites Neuroscience 51 1992 77 86
-
(1992)
Neuroscience
, vol.51
, pp. 77-86
-
-
Cimino, M.1
Marini, P.2
Fornasari, D.3
Cattabeni, F.4
Clementi, F.5
-
17
-
-
0030870199
-
125I]α- bungarotoxin binding
-
DOI 10.1016/S0891-0618(97)00038-0, PII S0891061897000380
-
D.P. Spurden, J.A. Court, S. Lloyd, A. Oakley, R. Perry, and C. Pearson Nicotinic receptor distribution in the human thalamus: autoradiographical localization of [3H]nicotine and [125I] alpha-bungarotoxin binding J Chem Neuroanat 13 1997 105 113 (Pubitemid 27397131)
-
(1997)
Journal of Chemical Neuroanatomy
, vol.13
, Issue.2
, pp. 105-113
-
-
Spurden, D.P.1
Court, J.A.2
Lloyd, S.3
Oakley, A.4
Perry, R.5
Pearson, C.6
Pullen, R.G.L.7
Perry, E.K.8
-
18
-
-
0030884260
-
125I]-α-bungarotoxin binding in human postmortem brain
-
DOI 10.1002/(SICI)1096-9861(19971027)387:3<385::AID-CNE5>3.0.CO;2-X
-
C.R. Breese, C. Adams, J. Logel, C. Drebing, Y. Rollins, and M. Barnhart Comparison of the regional expression of nicotinic acetylcholine receptor alpha7 mRNA and [125I]-alpha-bungarotoxin binding in human postmortem brain J Comp Neurol 387 1997 385 398 (Pubitemid 27430337)
-
(1997)
Journal of Comparative Neurology
, vol.387
, Issue.3
, pp. 385-398
-
-
Breese, C.R.1
Adams, C.2
Logel, J.3
Drebing, C.4
Rollins, Y.5
Barnhart, M.6
Sullivan, B.7
Demasters, B.K.8
Freedman, R.9
Leonard, S.10
-
19
-
-
79952167906
-
The thalamic reticular nucleus and schizophrenia
-
F. Ferrarelli, and G. Tononi The thalamic reticular nucleus and schizophrenia Schizophr Bull 37 2011 306 315
-
(2011)
Schizophr Bull
, vol.37
, pp. 306-315
-
-
Ferrarelli, F.1
Tononi, G.2
-
20
-
-
10644254858
-
Precise localization of α7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area
-
DOI 10.1523/JNEUROSCI.3009-04.2004
-
I.W. Jones, and S. Wonnacott Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area J Neurosci 24 2004 11244 11252 (Pubitemid 39658259)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.50
, pp. 11244-11252
-
-
Jones, I.W.1
Wonnacott, S.2
-
21
-
-
21344459009
-
3H]D-aspartate release from rat frontal cortex in vitro
-
DOI 10.1016/j.neuropharm.2005.01.030, PII S0028390805000687
-
S.J. Rousseau, I.W. Jones, I.A. Pullar, and S. Wonnacott Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro Neuropharmacology 49 2005 59 72 (Pubitemid 40910016)
-
(2005)
Neuropharmacology
, vol.49
, Issue.1
, pp. 59-72
-
-
Rousseau, S.J.1
Jones, I.W.2
Pullar, I.A.3
Wonnacott, S.4
-
22
-
-
0036325889
-
Direct evidence that release-stimulating α7*nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals
-
DOI 10.1046/j.0022-3042.2002.00805.x
-
M. Marchi, F. Risso, C. Viola, P. Cavazzani, and M. Raiteri Direct evidence that release-stimulating alpha7* nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals J Neurochem 80 2002 1071 1078 (Pubitemid 34809959)
-
(2002)
Journal of Neurochemistry
, vol.80
, Issue.6
, pp. 1071-1078
-
-
Marchi, M.1
Risso, F.2
Viola, C.3
Cavazzani, P.4
Raiteri, M.5
-
23
-
-
75049084941
-
Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by Alpha7 nicotinic receptors and potentiated by PNU-120596
-
P.D. Livingstone, J.A. Dickinson, J. Srinivasan, J.N. Kew, and S. Wonnacott Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by Alpha7 nicotinic receptors and potentiated by PNU-120596 J Mol Neurosci 40 2010 172 176
-
(2010)
J Mol Neurosci
, vol.40
, pp. 172-176
-
-
Livingstone, P.D.1
Dickinson, J.A.2
Srinivasan, J.3
Kew, J.N.4
Wonnacott, S.5
-
24
-
-
67349269521
-
Spatial and intracellular relationships between the alpha7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse
-
A.M. Duffy, P. Zhou, T.A. Milner, and V.M. Pickel Spatial and intracellular relationships between the alpha7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse Neuroscience 161 2009 1091 1103
-
(2009)
Neuroscience
, vol.161
, pp. 1091-1103
-
-
Duffy, A.M.1
Zhou, P.2
Milner, T.A.3
Pickel, V.M.4
-
25
-
-
47149106256
-
Preclinical characterization of A-582941: A novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties
-
K.R. Tietje, D.J. Anderson, R.S. Bitner, E.A. Blomme, P.J. Brackemeyer, and C.A. Briggs Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties CNS Neurosci Ther 14 2008 65 82
-
(2008)
CNS Neurosci Ther
, vol.14
, pp. 65-82
-
-
Tietje, K.R.1
Anderson, D.J.2
Bitner, R.S.3
Blomme, E.A.4
Brackemeyer, P.J.5
Briggs, C.A.6
-
26
-
-
33845698922
-
SSR180711, a novel selective α7 nicotinic receptor partial agonist: (1) Binding and functional profile
-
DOI 10.1038/sj.npp.1301189, PII 1301189
-
B. Biton, O.E. Bergis, F. Galli, A. Nedelec, A.W. Lochead, and S. Jegham SSR 180711, a novel selective alpha7 nicotinic receptor partial agonist: (1) binding and functional profile Neuropsychopharmacology 32 2007 1 16 (Pubitemid 44967780)
-
(2007)
Neuropsychopharmacology
, vol.32
, Issue.1
, pp. 1-16
-
-
Biton, B.1
Bergis, O.E.2
Galli, F.3
Nedelec, A.4
Lochead, A.W.5
Jegham, S.6
Godet, D.7
Lanneau, C.8
Santamaria, R.9
Chesney, F.10
Leonardon, J.11
Granger, P.12
Debono, M.W.13
Bohme, G.A.14
Sgard, F.15
Besnard, F.16
Graham, D.17
Coste, A.18
Oblin, A.19
Curet, O.20
Vige, X.21
Voltz, C.22
Rouquier, L.23
Souilhac, J.24
Santucci, V.25
Gueudet, C.26
Francon, D.27
Steinberg, R.28
Griebel, G.29
Oury-Donat, F.30
George, P.31
Avenet, P.32
Scatton, B.33
more..
-
27
-
-
68349141648
-
Nicotinic acetylcholine receptors and the ascending dopamine pathways
-
P.D. Livingstone, and S. Wonnacott Nicotinic acetylcholine receptors and the ascending dopamine pathways Biochem Pharmacol 78 2009 744 755
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 744-755
-
-
Livingstone, P.D.1
Wonnacott, S.2
-
28
-
-
0030858491
-
Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex
-
K.L. Summers, W.R. Kem, and E. Giacobini Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex Jpn J Pharmacol 74 1997 139 146 (Pubitemid 27331139)
-
(1997)
Japanese Journal of Pharmacology
, vol.74
, Issue.2
, pp. 139-146
-
-
Summers, K.L.1
Kem, W.R.2
Giacobini, E.3
-
29
-
-
0019890828
-
Calcium and the control of synaptic strength by learning
-
E.R. Kandel Calcium and the control of synaptic strength by learning Nature 293 1981 697 700
-
(1981)
Nature
, vol.293
, pp. 697-700
-
-
Kandel, E.R.1
-
30
-
-
33846783267
-
Differential coupling of α7 and non-α7 nicotinic acetylcholine receptors to calcium-induced calcium release and voltage-operated calcium channels in PC12 cells
-
DOI 10.1111/j.1471-4159.2006.04273.x
-
J.A. Dickinson, K.E. Hanrott, M.H. Mok, J.N. Kew, and S. Wonnacott Differential coupling of alpha7 and non-alpha7 nicotinic acetylcholine receptors to calcium-induced calcium release and voltage-operated calcium channels in PC12 cells J Neurochem 100 2007 1089 1096 (Pubitemid 46213931)
-
(2007)
Journal of Neurochemistry
, vol.100
, Issue.4
, pp. 1089-1096
-
-
Dickinson, J.A.1
Hanrott, K.E.2
Mok, M.H.S.3
Kew, J.N.C.4
Wonnacott, S.5
-
31
-
-
0033118561
-
Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices
-
M. Alkondon, E.F. Pereira, and H.M. Eisenberg Albuquerque EX. Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices J Neurosci 19 1999 2693 2705 (Pubitemid 29162417)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.7
, pp. 2693-2705
-
-
Alkondon, M.1
Pereira, E.F.R.2
Eisenberg, H.M.3
Albuquerque, E.X.4
-
32
-
-
0033995561
-
Nicotinic receptor activation in human cerebral cortical interneurons: A mechanism for inhibition and disinhibition of neuronal networks
-
M. Alkondon, E.F. Pereira, and H.M. Eisenberg Albuquerque EX. Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for inhibition and disinhibition of neuronal networks J Neurosci 20 2000 66 75 (Pubitemid 30220492)
-
(2000)
Journal of Neuroscience
, vol.20
, Issue.1
, pp. 66-75
-
-
Alkondon, M.1
Pereira, E.F.R.2
Eisenberg, H.M.3
Albuquerque, E.X.4
-
33
-
-
0035886019
-
Ultrastructural distribution of the α7 nicotinic acetylcholine receptor subunit in rat hippocampus
-
R. Fabian-Fine, P. Skehel, M.L. Errington, H.A. Davies, E. Sher, and M.G. Stewart Ultrastructural distribution of the alpha7 nicotinic acetylcholine receptor subunit in rat hippocampus J Neurosci 21 2001 7993 8003 (Pubitemid 32952756)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.20
, pp. 7993-8003
-
-
Fabian-Fine, R.1
Skehel, P.2
Errington, M.L.3
Davies, H.A.4
Sher, E.5
Stewart, M.G.6
Fine, A.7
-
34
-
-
2542486433
-
Nicotinic acetylcholine receptors and the regulation of neuronal signalling
-
DOI 10.1016/j.tips.2004.04.006, PII S016561470400118X
-
F. Dajas-Bailador, and S. Wonnacott Nicotinic acetylcholine receptors and the regulation of neuronal signalling Trends Pharmacol Sci 25 2004 317 324 (Pubitemid 38692424)
-
(2004)
Trends in Pharmacological Sciences
, vol.25
, Issue.6
, pp. 317-324
-
-
Dajas-Bailador, F.1
Wonnacott, S.2
-
35
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
DOI 10.1038/361031a0
-
T.V. Bliss, and G.L. Collingridge A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 1993 31 39 (Pubitemid 23020772)
-
(1993)
Nature
, vol.361
, Issue.6407
, pp. 31-39
-
-
Bliss, T.V.P.1
Collingridge, G.L.2
-
36
-
-
33845676294
-
Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus
-
DOI 10.1111/j.1460-9568.2006.05187.x
-
P. Welsby, M. Rowan, and R. Anwyl Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus Eur J Neurosci 24 2006 3109 3118 (Pubitemid 44952643)
-
(2006)
European Journal of Neuroscience
, vol.24
, Issue.11
, pp. 3109-3118
-
-
Welsby, P.1
Rowan, M.2
Anwyl, R.3
-
37
-
-
34547165139
-
Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP
-
DOI 10.1016/j.neuropharm.2007.05.013, PII S0028390807001505
-
P.J. Welsby, M.J. Rowan, and R. Anwyl Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP Neuropharmacology 53 2007 188 195 (Pubitemid 47125959)
-
(2007)
Neuropharmacology
, vol.53
, Issue.1
, pp. 188-195
-
-
Welsby, P.J.1
Rowan, M.J.2
Anwyl, R.3
-
38
-
-
78650797928
-
RG3487, a novel nicotinic alpha 7 receptor partial agonist, improves cognition and sensorimotor gating in rodents
-
T.L. Wallace, P.M. Callahan, A. Tehim, D. Bertrand, G. Tombaugh, and S. Wang RG3487, a novel nicotinic alpha 7 receptor partial agonist, improves cognition and sensorimotor gating in rodents J Pharmacol Exp Ther 336 2011 242 253
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 242-253
-
-
Wallace, T.L.1
Callahan, P.M.2
Tehim, A.3
Bertrand, D.4
Tombaugh, G.5
Wang, S.6
-
39
-
-
34848925196
-
Broad-spectrum efficacy across cognitive domains by α7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways
-
DOI 10.1523/JNEUROSCI.2444-07.2007
-
R.S Bitner, W.H. Bunnelle, D.J. Anderson, C.A. Briggs, J. Buccafusco, and P. Curzon Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways J Neurosci 27 2007 10578 10587 (Pubitemid 47502013)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.39
, pp. 10578-10587
-
-
Bitner, R.S.1
Bunnelle, W.H.2
Anderson, D.J.3
Briggs, C.A.4
Buccafusco, J.5
Curzon, P.6
Decker, M.W.7
Frost, J.M.8
Gronlien, J.H.9
Gubbins, E.10
Li, J.11
Malysz, J.12
Markosyan, S.13
Marsh, K.14
Meyer, M.D.15
Nikkel, A.L.16
Radek, R.J.17
Robb, H.M.18
Timmermann, D.19
Sullivan, J.P.20
Gopalakrishnan, M.21
more..
-
40
-
-
0028108923
-
CREB: A mediator of long-term memory from mollusks to mammals
-
DOI 10.1016/0092-8674(94)90394-8
-
D.A. Frank, and M.E. Greenberg CREB: a mediator of long-term memory from mollusks to mammals Cell 79 1994 5 8 (Pubitemid 24309507)
-
(1994)
Cell
, vol.79
, Issue.1
, pp. 5-8
-
-
Frank, D.A.1
Greenberg, M.E.2
-
41
-
-
46549086401
-
The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat
-
M.S. Thomsen, J.D. Mikkelsen, D.B. Timmermann, D. Peters, A. Hay-Schmidt, and H. Martens The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: differential effects in the juvenile and adult rat Neuroscience 154 2008 741 753
-
(2008)
Neuroscience
, vol.154
, pp. 741-753
-
-
Thomsen, M.S.1
Mikkelsen, J.D.2
Timmermann, D.B.3
Peters, D.4
Hay-Schmidt, A.5
Martens, H.6
-
42
-
-
0036891571
-
Desensitization of neuronal nicotinic receptors
-
DOI 10.1002/neu.10109
-
M.W. Quick, and R.A. Lester Desensitization of neuronal nicotinic receptors J Neurobiol 53 2002 457 478 (Pubitemid 35375579)
-
(2002)
Journal of Neurobiology
, vol.53
, Issue.4
, pp. 457-478
-
-
Quick, M.W.1
Lester, R.A.J.2
-
43
-
-
0034602138
-
Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons
-
A. Mike, N.G. Castro, and E.X. Albuquerque Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons Brain Res 882 2000 155 168
-
(2000)
Brain Res
, vol.882
, pp. 155-168
-
-
Mike, A.1
Castro, N.G.2
Albuquerque, E.X.3
-
44
-
-
20744449198
-
Desensitization of nicotinic ACh receptors: Shaping cholinergic signaling
-
DOI 10.1016/j.tins.2005.04.009, PII S0166223605001098
-
R. Giniatullin, A. Nistri, and J.L. Yakel Desensitization of nicotinic ACh receptors: shaping cholinergic signaling Trends Neurosci 28 2005 371 378 (Pubitemid 40853860)
-
(2005)
Trends in Neurosciences
, vol.28
, Issue.7
, pp. 371-378
-
-
Giniatullin, R.1
Nistri, A.2
Yakel, J.L.3
-
45
-
-
0041377930
-
Nicotine as a modulator of behavior: Beyond the inverted U
-
DOI 10.1016/S0165-6147(03)00230-X
-
M.R. Picciotto Nicotine as a modulator of behavior: beyond the inverted U Trends Pharmacol Sci 24 2003 493 499 (Pubitemid 37088175)
-
(2003)
Trends in Pharmacological Sciences
, vol.24
, Issue.9
, pp. 493-499
-
-
Picciotto, M.R.1
-
46
-
-
80052023505
-
-
Society for Neuroscience Annual Meeting San Diego, California p. 113
-
T.L. Wallace, G. Chiu, H. Dao, L. Santarelli, R. Porter, and S. Bertrand Modulation of cholinergic tone impacts the efficacy of RG3487/MEM3454, a novel, nicotinic alpha 7 receptor agonist 2010 Society for Neuroscience Annual Meeting San Diego, California p. 113
-
(2010)
Modulation of Cholinergic Tone Impacts the Efficacy of RG3487/MEM3454, A Novel, Nicotinic Alpha 7 Receptor Agonist
-
-
Wallace, T.L.1
Chiu, G.2
Dao, H.3
Santarelli, L.4
Porter, R.5
Bertrand, S.6
-
47
-
-
59649098711
-
Desensitization of nicotinic acetylcholine receptors as a strategy for drug development
-
J.J. Buccafusco, J.W. Beach, and A.V. Terry Jr. Desensitization of nicotinic acetylcholine receptors as a strategy for drug development J Pharmacol Exp Ther 328 2009 364 370
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 364-370
-
-
Buccafusco, J.J.1
Beach, J.W.2
Terry, Jr.A.V.3
-
48
-
-
0034724994
-
Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region
-
DOI 10.1016/S0006-8993(00)02119-3, PII S0006899300021193
-
S. Fujii, Y. Jia, A. Yang, and K. Sumikawa Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region Brain Res 863 2000 259 265 (Pubitemid 30201607)
-
(2000)
Brain Research
, vol.863
, Issue.1-2
, pp. 259-265
-
-
Fujii, S.1
Jia, Y.2
Yang, A.3
Sumikawa, K.4
-
49
-
-
0033372817
-
Differential improvement in memory-related task performance with nicotine by aged male and female rhesus monkeys
-
J.J. Buccafusco, W.J. Jackson, R.R. Jonnala, and A.V. Terry Jr. Differential improvement in memory-related task performance with nicotine by aged male and female rhesus monkeys Behav Pharmacol 10 1999 681 690 (Pubitemid 30026063)
-
(1999)
Behavioural Pharmacology
, vol.10
, Issue.6-7
, pp. 681-690
-
-
Buccafusco, J.J.1
Jackson, W.J.2
Jonnala, R.R.3
Terry Jr., A.V.4
-
50
-
-
33845719612
-
SSR180711, a novel selective α7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia
-
DOI 10.1038/sj.npp.1301188, PII 1301188
-
P. Pichat, O.E. Bergis, J.P. Terranova, A. Urani, C. Duarte, and V. Santucci SSR 180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia Neuropsychopharmacology 32 2007 17 34 (Pubitemid 44967781)
-
(2007)
Neuropsychopharmacology
, vol.32
, Issue.1
, pp. 17-34
-
-
Pichat, P.1
Bergis, O.E.2
Terranova, J.-P.3
Urani, A.4
Duarte, C.5
Santucci, V.6
Gueudet, C.7
Voltz, C.8
Steinberg, R.9
Stemmelin, J.10
Oury-Donat, F.11
Avenet, P.12
Griebel, G.13
Scatton, B.14
-
51
-
-
65649092520
-
Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders
-
R. Roncarati, C. Scali, T.A. Comery, S.M. Grauer, S. Aschmi, and H. Bothmann Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders J Pharmacol Exp Ther 329 2009 459 468
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 459-468
-
-
Roncarati, R.1
Scali, C.2
Comery, T.A.3
Grauer, S.M.4
Aschmi, S.5
Bothmann, H.6
-
52
-
-
80052023415
-
-
Society for Neuroscience Chicago, Illinois p. 1137
-
G. Koenig, M.G. Palfreyman, R. Chesworth, G. Shapiro, J. Prickaerts, and O.A.H. Reneerkens EVP-6124, a novel and potent alpha7 nicotinic acetylcholine receptor agonist, improves memory acquisition, retention and retrieval and reverses scopolamine-induced memory deficits 2009 Society for Neuroscience Chicago, Illinois p. 1137
-
(2009)
EVP-6124, A Novel and Potent alpha7 Nicotinic Acetylcholine Receptor Agonist, Improves Memory Acquisition, Retention and Retrieval and Reverses Scopolamine-induced Memory Deficits
-
-
Koenig, G.1
Palfreyman, M.G.2
Chesworth, R.3
Shapiro, G.4
Prickaerts, J.5
Reneerkens, O.A.H.6
-
53
-
-
0030011343
-
Comparison of the effects of the 5-HT3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic projection system
-
H. Hodges, P. Sowinski, J.J. Turner, and A. Fletcher Comparison of the effects of the 5-HT3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic projection system Psychopharmacology (Berl) 125 1996 146 161
-
(1996)
Psychopharmacology (Berl)
, vol.125
, pp. 146-161
-
-
Hodges, H.1
Sowinski, P.2
Turner, J.J.3
Fletcher, A.4
-
54
-
-
0030976574
-
Different effects of tropisetron and ondansetron in learning and memory paradigms
-
DOI 10.1016/S0091-3057(96)00516-3, PII S0091305796005163
-
N. Pitsikas, and F. Borsini Different effects of tropisetron and ondansetron in learning and memory paradigms Pharmacol Biochem Behav 56 1997 571 576 (Pubitemid 27189738)
-
(1997)
Pharmacology Biochemistry and Behavior
, vol.56
, Issue.4
, pp. 571-576
-
-
Pitsikas, N.1
Borsini, F.2
-
55
-
-
0028934741
-
Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21
-
G.W. Arendash, G.J. Sengstock, P.R. Sanberg, and W.R. Kem Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21 Brain Res 674 1995 252 259
-
(1995)
Brain Res
, vol.674
, pp. 252-259
-
-
Arendash, G.W.1
Sengstock, G.J.2
Sanberg, P.R.3
Kem, W.R.4
-
56
-
-
43149119474
-
Comparative effects of the alpha7 nicotinic partial agonist S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice
-
A. Marighetto, S. Valerio, A. Desmedt, J.N. Philippin, C. Trocme-Thibierge, and P. Morain Comparative effects of the alpha7 nicotinic partial agonist S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice Psychopharmacology (Berl) 197 2008 499 508
-
(2008)
Psychopharmacology (Berl)
, vol.197
, pp. 499-508
-
-
Marighetto, A.1
Valerio, S.2
Desmedt, A.3
Philippin, J.N.4
Trocme-Thibierge, C.5
Morain, P.6
-
57
-
-
0002100551
-
3-[2,4-dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat α 7 receptors and improves memory-related behaviors in a mecamylamine- sensitive manner
-
DOI 10.1016/S0006-8993(97)00536-2, PII S0006899397005362
-
E.M. Meyer, E.T. Tay, R.L. Papke, C. Meyers, G.L. Huang, and C.M. de Fiebre 3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine- sensitive manner Brain Res 768 1997 49 56 (Pubitemid 27433476)
-
(1997)
Brain Research
, vol.768
, Issue.1-2
, pp. 49-56
-
-
Meyer, E.M.1
Tay, E.T.2
Papke, R.L.3
Meyers, C.4
Huang, G.-L.5
De Fiebre, C.M.6
-
58
-
-
67349167960
-
Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR 180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia
-
S. Barak, M. Arad, A. De Levie, M.D. Black, G. Griebel, and I. Weiner Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR 180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia Neuropsychopharmacology 34 2009 1753 1763
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 1753-1763
-
-
Barak, S.1
Arad, M.2
De Levie, A.3
Black, M.D.4
Griebel, G.5
Weiner, I.6
-
59
-
-
0030858125
-
Functional and anatomical aspects of prefrontal pathology in schizophrenia
-
P.S. Goldman-Rakic, and L.D. Selemon Functional and anatomical aspects of prefrontal pathology in schizophrenia Schizophr Bull 23 1997 437 458 (Pubitemid 27427984)
-
(1997)
Schizophrenia Bulletin
, vol.23
, Issue.3
, pp. 437-458
-
-
Qoldman-Rakic, P.S.1
Selemon, L.D.2
-
60
-
-
0033237390
-
AR-R17779, an α7 nicotinic agonist, improves learning and memory in rats
-
E.D. Levin, C. Bettegowda, J. Blosser, and J. Gordon AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats Behav Pharmacol 10 1999 675 680 (Pubitemid 30026062)
-
(1999)
Behavioural Pharmacology
, vol.10
, Issue.6-7
, pp. 675-680
-
-
Levin, E.D.1
Bettegowda, C.2
Blosser, J.3
Gordon, J.4
-
61
-
-
0035708467
-
Ventral hippocampal α7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze
-
DOI 10.1016/S0091-3057(01)00643-8, PII S0091305701006438
-
J.H. Bettany, and E.D. Levin Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze Pharmacol Biochem Behav 70 2001 467 474 (Pubitemid 34131641)
-
(2001)
Pharmacology Biochemistry and Behavior
, vol.70
, Issue.4
, pp. 467-474
-
-
Bettany, J.H.1
Levin, E.D.2
-
62
-
-
33645741208
-
Dorsal hippocampal alpha7 and alpha4beta2 nicotinic receptors and memory
-
A. Nott, and E.D. Levin Dorsal hippocampal alpha7 and alpha4beta2 nicotinic receptors and memory Brain Res 1081 2006 72 78
-
(2006)
Brain Res
, vol.1081
, pp. 72-78
-
-
Nott, A.1
Levin, E.D.2
-
63
-
-
0037154981
-
Hippocampal α7 and α4β2 nicotinic receptors and working memory
-
DOI 10.1016/S0306-4522(01)00538-3, PII S0306452201005383
-
E.D. Levin, A. Bradley, N. Addy, and N. Sigurani Hippocampal alpha 7 and alpha 4 beta 2 nicotinic receptors and working memory Neuroscience 109 2002 757 765 (Pubitemid 34260859)
-
(2002)
Neuroscience
, vol.109
, Issue.4
, pp. 757-765
-
-
Levin, E.D.1
Bradley, A.2
Addy, N.3
Sigurani, N.4
-
64
-
-
33746870022
-
Performance deficit of α7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory
-
DOI 10.1111/j.1601-183X.2005.00176.x
-
C. Fernandes, E. Hoyle, E. Dempster, L.C. Schalkwyk, and D.A. Collier Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory Genes Brain Behav 5 2006 433 440 (Pubitemid 44199563)
-
(2006)
Genes, Brain and Behavior
, vol.5
, Issue.6
, pp. 433-440
-
-
Fernandes, C.1
Hoyle, E.2
Dempster, E.3
Schalkwyk, L.C.4
Collier, D.A.5
-
65
-
-
0031003185
-
Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo
-
DOI 10.1016/S0091-3057(96)00354-1, PII S0091305796003541
-
C.A. Briggs, D.J. Anderson, J.D. Brioni, J.J. Buccafusco, M.J. Buckley, and J.E. Campbell Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo Pharmacol Biochem Behav 57 1997 231 241 (Pubitemid 27261416)
-
(1997)
Pharmacology Biochemistry and Behavior
, vol.57
, Issue.1-2
, pp. 231-241
-
-
Briggs, C.A.1
Anderson, D.J.2
Brioni, J.D.3
Buccafusco, J.J.4
Buckley, M.J.5
Campbell, J.E.6
Decker, M.W.7
Donnelly-Roberts, D.8
Elliott, R.L.9
Gopalakrishnan, M.10
Holladay, M.W.11
Hui, Y.-H.12
Jackson, W.J.13
Kim, D.J.B.14
Marsh, K.C.15
O'Neill, A.16
Prendergast, M.A.17
Ryther, K.B.18
Sullivan, J.P.19
Arneric, S.P.20
more..
-
66
-
-
77956247430
-
In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: Preclinical considerations in Alzheimer's disease
-
R.S. Bitner, W.H. Bunnelle, M.W. Decker, K.U. Drescher, K.L. Kohlhaas, and S. Markosyan In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease J Pharmacol Exp Ther 334 2010 875 886
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 875-886
-
-
Bitner, R.S.1
Bunnelle, W.H.2
Decker, M.W.3
Drescher, K.U.4
Kohlhaas, K.L.5
Markosyan, S.6
-
67
-
-
80052033258
-
-
Society for Neuroscience Annual Meeting Chicago, Illinois
-
T.L. Wallace, G. Chiu, H. Dao, D.A. Lowe, R. Porter, and L. Santarelli R3487/MEM 3454, a novel nicotinic alpha 7 receptor partial agonist, improves attention and working memory performance in cynomolgus macaques 2009 Society for Neuroscience Annual Meeting Chicago, Illinois
-
(2009)
R3487/MEM 3454, A Novel Nicotinic Alpha 7 Receptor Partial Agonist, Improves Attention and Working Memory Performance in Cynomolgus Macaques
-
-
Wallace, T.L.1
Chiu, G.2
Dao, H.3
Lowe, D.A.4
Porter, R.5
Santarelli, L.6
-
68
-
-
78649994788
-
Immediate and sustained improvements in working memory after selective stimulation of alpha7 nicotinic acetylcholine receptors
-
S.A. Castner, G.N. Smagin, T.M. Piser, Y. Wang, J.S. Smith, and E.P. Christian Immediate and sustained improvements in working memory after selective stimulation of alpha7 nicotinic acetylcholine receptors Biol Psychiatry 69 2011 12 18
-
(2011)
Biol Psychiatry
, vol.69
, pp. 12-18
-
-
Castner, S.A.1
Smagin, G.N.2
Piser, T.M.3
Wang, Y.4
Smith, J.S.5
Christian, E.P.6
-
69
-
-
33751334112
-
Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice
-
DOI 10.1016/j.euroneuro.2006.03.008, PII S0924977X06000642
-
J.W. Young, N. Crawford, J.S. Kelly, L.E. Kerr, H.M. Marston, and C. Spratt Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice Eur Neuropsychopharmacol 17 2007 145 155 (Pubitemid 44802833)
-
(2007)
European Neuropsychopharmacology
, vol.17
, Issue.2
, pp. 145-155
-
-
Young, J.W.1
Crawford, N.2
Kelly, J.S.3
Kerr, L.E.4
Marston, H.M.5
Spratt, C.6
Finlayson, K.7
Sharkey, J.8
-
70
-
-
33750613621
-
Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task
-
DOI 10.1007/s00213-006-0549-2
-
E. Hoyle, R.F. Genn, C. Fernandes, and I.P. Stolerman Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task Psychopharmacology (Berl) 189 2006 211 223 (Pubitemid 44691543)
-
(2006)
Psychopharmacology
, vol.189
, Issue.2
, pp. 211-223
-
-
Hoyle, E.1
Genn, R.F.2
Fernandes, C.3
Stolerman, I.P.4
-
71
-
-
60049101441
-
Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats
-
A.H. Rezvani, E. Kholdebarin, F.H. Brucato, P.M. Callahan, D.A. Lowe, and E.D. Levin Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats Prog Neuropsychopharmacol Biol Psychiatry 33 2009 269 275
-
(2009)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.33
, pp. 269-275
-
-
Rezvani, A.H.1
Kholdebarin, E.2
Brucato, F.H.3
Callahan, P.M.4
Lowe, D.A.5
Levin, E.D.6
-
72
-
-
0034694951
-
Effect of subtype selective nicotinic compounds on attention as assessed by the five-choice serial reaction time task
-
A.J. Grottick, and G.A. Higgins Effect of subtype selective nicotinic compounds on attention as assessed by the five-choice serial reaction time task Behav Brain Res 117 2000 197 208
-
(2000)
Behav Brain Res
, vol.117
, pp. 197-208
-
-
Grottick, A.J.1
Higgins, G.A.2
-
73
-
-
0037712944
-
Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands
-
A.J. Grottick, M. Haman, R. Wyler, and G.A. Higgins Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands Neuropsychopharmacology 28 2003 880 887
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 880-887
-
-
Grottick, A.J.1
Haman, M.2
Wyler, R.3
Higgins, G.A.4
-
74
-
-
0038368835
-
Attentional effects of nicotinic agonists in rats
-
DOI 10.1016/S0028-3908(03)00099-6
-
B. Hahn, C.G. Sharples, S. Wonnacott, M. Shoaib, and I.P. Stolerman Attentional effects of nicotinic agonists in rats Neuropharmacology 44 2003 1054 1067 (Pubitemid 36570430)
-
(2003)
Neuropharmacology
, vol.44
, Issue.8
, pp. 1054-1067
-
-
Hahn, B.1
Sharples, C.G.V.2
Wonnacott, S.3
Shoaib, M.4
Stolerman, I.P.5
-
75
-
-
0034019113
-
Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: Antagonist studies
-
DOI 10.1007/s002130000378
-
A. Blondel, D.J. Sanger, and P.C. Moser Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: antagonist studies Psychopharmacology (Berl) 149 2000 293 305 (Pubitemid 30262344)
-
(2000)
Psychopharmacology
, vol.149
, Issue.3
, pp. 293-305
-
-
Blondel, A.1
Sanger, D.J.2
Moser, P.C.3
-
76
-
-
67349209574
-
A cog in cognition: How the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits
-
S.C. Leiser, M.R. Bowlby, T.A. Comery, and J. Dunlop A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits Pharmacol Ther 122 2009 302 311
-
(2009)
Pharmacol Ther
, vol.122
, pp. 302-311
-
-
Leiser, S.C.1
Bowlby, M.R.2
Comery, T.A.3
Dunlop, J.4
-
77
-
-
3142761435
-
Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia
-
L.F. Martin, W.R. Kem, and R. Freedman Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia Psychopharmacology (Berl) 174 2004 54 64 (Pubitemid 38925091)
-
(2004)
Psychopharmacology
, vol.174
, Issue.1
, pp. 54-64
-
-
Martin, L.F.1
Kem, W.R.2
Freedman, R.3
-
78
-
-
14344251489
-
The selective α7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats
-
DOI 10.1124/jpet.104.076968
-
M. Hajos, R.S. Hurst, W.E. Hoffmann, M. Krause, T.M. Wall, and N.R. Higdon The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats J Pharmacol Exp Ther 312 2005 1213 1222 (Pubitemid 40293783)
-
(2005)
Journal of Pharmacology and Experimental Therapeutics
, vol.312
, Issue.3
, pp. 1213-1222
-
-
Hajos, M.1
Hurst, R.S.2
Hoffmann, W.E.3
Krause, M.4
Wall, T.M.5
Higdon, N.R.6
Groppi, V.E.7
-
79
-
-
0034926925
-
The DBA/2J strain and prepulse inhibition of startle: A model system to test antipsychotics?
-
DOI 10.1007/s002130100828
-
B. Olivier, C. Leahy, T. Mullen, R. Paylor, V.E. Groppi, and Z. Sarnyai The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics? Psychopharmacology (Berl) 156 2001 284 290 (Pubitemid 32702219)
-
(2001)
Psychopharmacology
, vol.156
, Issue.2-3
, pp. 284-290
-
-
Olivier, B.1
Leahy, C.2
Mullen, T.3
Paylor, R.4
Groppi, V.E.5
Sarnyai, Z.6
Brunner, D.7
-
80
-
-
0031596817
-
7-nicotinic agonists normalize inhibition of auditory response in DBA mice
-
DOI 10.1007/s002130050573
-
K.E. Stevens, W.R. Kem, V.M. Mahnir, and R. Freedman Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice Psychopharmacology (Berl) 136 1998 320 327 (Pubitemid 28189660)
-
(1998)
Psychopharmacology
, vol.136
, Issue.4
, pp. 320-327
-
-
Stevens, K.E.1
Kem, W.R.2
Mahnir, V.M.3
Freedman, R.4
-
81
-
-
0026664965
-
Cholinergic gating of response to auditory stimuli in rat hippocampus
-
V. Luntz-Leybman, P.C. Bickford, and R. Freedman Cholinergic gating of response to auditory stimuli in rat hippocampus Brain Res 587 1992 130 136
-
(1992)
Brain Res
, vol.587
, pp. 130-136
-
-
Luntz-Leybman, V.1
Bickford, P.C.2
Freedman, R.3
-
82
-
-
0141993546
-
7 nicotinic agonist, normalizes auditory gating in isolation-reared rats
-
DOI 10.1007/s00213-003-1482-2
-
H.C. O'Neill, K. Rieger, W.R. Kem, and K.E. Stevens DMXB, an alpha7 nicotinic agonist, normalizes auditory gating in isolation-reared rats Psychopharmacology (Berl) 169 2003 332 339 (Pubitemid 37255522)
-
(2003)
Psychopharmacology
, vol.169
, Issue.3-4
, pp. 332-339
-
-
O'Neill, H.C.1
Rieger, K.2
Kem, W.R.3
Stevens, K.E.4
-
83
-
-
0036170063
-
7-nicotine acetylcholine receptor agonists on prepulse inhibition of the acoustic startle response in rats and mice
-
DOI 10.1007/s00213-001-0927-8
-
R. Schreiber, M. Dalmus, and J. De Vry Effects of alpha 4/beta 2- and alpha 7-nicotine acetylcholine receptor agonists on prepulse inhibition of the acoustic startle response in rats and mice Psychopharmacology (Berl) 159 2002 248 257 (Pubitemid 34143373)
-
(2002)
Psychopharmacology
, vol.159
, Issue.3
, pp. 248-257
-
-
Schreiber, R.1
Dalmus, M.2
De Vry, J.3
-
84
-
-
0033377797
-
Sensory gating in rats: Lack of correlation between auditory evoked potential gating and prepulse inhibition
-
B.A. Ellenbroek, G. van Luijtelaar, M. Frenken, and A.R. Cools Sensory gating in rats: lack of correlation between auditory evoked potential gating and prepulse inhibition Schizophr Bull 25 1999 777 788 (Pubitemid 30013559)
-
(1999)
Schizophrenia Bulletin
, vol.25
, Issue.4
, pp. 777-788
-
-
Ellenbroek, B.A.1
Van Luijtelaar, G.2
Frenken, M.3
Cools, A.R.4
-
85
-
-
20444463577
-
A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors
-
DOI 10.1016/j.schres.2005.02.010, PII S0920996405000757
-
J. de Leon, and F.J. Diaz A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors Schizophr Res 76 2005 135 157 (Pubitemid 40812332)
-
(2005)
Schizophrenia Research
, vol.76
, Issue.2-3
, pp. 135-157
-
-
De Leon, J.1
Diaz, F.J.2
-
86
-
-
67651091553
-
Prefrontal cognitive dysfunction is associated with tobacco dependence treatment failure in smokers with schizophrenia
-
T.G. Moss, K.A. Sacco, T.M. Allen, A.H. Weinberger, J.C. Vessicchio, and T.P. George Prefrontal cognitive dysfunction is associated with tobacco dependence treatment failure in smokers with schizophrenia Drug Alcohol Depend 104 2009 94 99
-
(2009)
Drug Alcohol Depend
, vol.104
, pp. 94-99
-
-
Moss, T.G.1
Sacco, K.A.2
Allen, T.M.3
Weinberger, A.H.4
Vessicchio, J.C.5
George, T.P.6
-
87
-
-
20944441082
-
A novel positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor: In vitro and in vivo characterization
-
DOI 10.1523/JNEUROSCI.5269-04.2005
-
R.S. Hurst, M. Hajos, M. Raggenbass, T.M. Wall, N.R. Higdon, and J.A. Lawson A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization J Neurosci 25 2005 4396 4405 (Pubitemid 40628784)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.17
, pp. 4396-4405
-
-
Hurst, R.S.1
Hajos, M.2
Raggenbass, M.3
Wall, T.M.4
Higdon, N.R.5
Lawson, J.A.6
Rutherford-Root, K.L.7
Berkenpas, M.B.8
Hoffmann, W.E.9
Piotrowski, D.W.10
Groppi, V.E.11
Allaman, G.12
Ogier, R.13
Bertrand, S.14
Bertrand, D.15
Arneric, S.P.16
-
88
-
-
34249947698
-
A receptor modulators
-
DOI 10.1073/pnas.0701321104
-
H.J. Ng, E.R. Whittemore, M.B. Tran, D.J. Hogenkamp, R.S. Broide, and T.B. Johnstone Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators Proc Natl Acad Sci USA 104 2007 8059 8064 (Pubitemid 47185875)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.19
, pp. 8059-8064
-
-
Ng, H.J.1
Whittemore, E.R.2
Tran, M.B.3
Hogenkamp, D.J.4
Broide, R.S.5
Johnstone, T.B.6
Zheng, L.7
Stevens, K.E.8
Gee, K.W.9
-
89
-
-
78751507926
-
Characterization of 2-[[4-fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4- pyridinyl)-5-thiazoleme thanol (JNJ-1930942), a novel positive allosteric modulator of the {alpha}7 nicotinic acetylcholine receptor
-
T. Dinklo, H. Shaban, J.W. Thuring, H. Lavreysen, K.E. Stevens, and L. Zheng Characterization of 2-[[4-fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4- pyridinyl)-5-thiazoleme thanol (JNJ-1930942), a novel positive allosteric modulator of the {alpha}7 nicotinic acetylcholine receptor J Pharmacol Exp Ther 336 2011 560 574
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 560-574
-
-
Dinklo, T.1
Shaban, H.2
Thuring, J.W.3
Lavreysen, H.4
Stevens, K.E.5
Zheng, L.6
-
90
-
-
62449113374
-
Old and new pharmacology: Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5- b′]di pyrrole-1(2H)-carboxamide)
-
J. Dunlop, T. Lock, B. Jow, F. Sitzia, S. Grauer, and F. Jow Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b′]di pyrrole-1(2H)-carboxamide) J Pharmacol Exp Ther 328 2009 766 776
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 766-776
-
-
Dunlop, J.1
Lock, T.2
Jow, B.3
Sitzia, F.4
Grauer, S.5
Jow, F.6
-
91
-
-
34548689531
-
An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo
-
DOI 10.1124/jpet.107.120436
-
D.B. Timmermann, J.H. Gronlien, K.L. Kohlhaas, E.O. Nielsen, E. Dam, and T.D. Jorgensen An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo J Pharmacol Exp Ther 323 2007 294 307 (Pubitemid 47443280)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.323
, Issue.1
, pp. 294-307
-
-
Timmermann, D.B.1
Gronlien, J.H.2
Kohlhaas, K.L.3
Nielsen, E.O.4
Dam, E.5
Jorgensen, T.D.6
Ahring, P.K.7
Peters, D.8
Holst, D.9
Chrsitensen, J.K.10
Malysz, J.11
Briggs, C.A.12
Gopalakrishnan, M.13
Olsen, G.M.14
-
93
-
-
32844461888
-
Nicotinic effects on cognitive function: Behavioral characterization, pharmacological specification, and anatomic localization
-
DOI 10.1007/s00213-005-0164-7
-
E.D. Levin, F.J. McClernon, and A.H. Rezvani Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization Psychopharmacology (Berl) 184 2006 523 539 (Pubitemid 43255869)
-
(2006)
Psychopharmacology
, vol.184
, Issue.3-4
, pp. 523-539
-
-
Levin, E.D.1
McClernon, F.J.2
Rezvani, A.H.3
-
94
-
-
0033626286
-
The brain α7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: Studies with DMXBA (GTS-21)
-
DOI 10.1016/S0166-4328(00)00211-4, PII S0166432800002114
-
W.R. Kem The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21) Behav Brain Res 113 2000 169 181 (Pubitemid 30645554)
-
(2000)
Behavioural Brain Research
, vol.113
, Issue.1-2
, pp. 169-181
-
-
Kem, W.R.1
-
96
-
-
33645319504
-
Targeting the alpha 7 nicotinic acetylcholine receptor to reduce amyloid accumulation in Alzheimer's disease pyramidal neurons
-
M.R. D'Andrea, and R.G. Nagele Targeting the alpha 7 nicotinic acetylcholine receptor to reduce amyloid accumulation in Alzheimer's disease pyramidal neurons Curr Pharm Des 12 2006 677 684
-
(2006)
Curr Pharm des
, vol.12
, pp. 677-684
-
-
D'Andrea, M.R.1
Nagele, R.G.2
-
97
-
-
33744726880
-
Selective α7 nicotinic acetylcholine receptor ligands
-
DOI 10.2174/092986706777442011
-
A. Mazurov, T. Hauser, and C.H. Miller Selective alpha7 nicotinic acetylcholine receptor ligands Curr Med Chem 13 2006 1567 1584 (Pubitemid 43821705)
-
(2006)
Current Medicinal Chemistry
, vol.13
, Issue.13
, pp. 1567-1584
-
-
Mazurov, A.1
Hauser, T.2
Miller, C.H.3
-
98
-
-
0033983966
-
Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
-
DOI 10.1046/j.1471-4159.2000.0740237.x
-
Z.Z. Guan, X. Zhang, R. Ravid, and A. Nordberg Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease J Neurochem 74 2000 237 243 (Pubitemid 30012774)
-
(2000)
Journal of Neurochemistry
, vol.74
, Issue.1
, pp. 237-243
-
-
Guan, Z.-Z.1
Zhang, X.2
Ravid, R.3
Nordberg, A.4
-
99
-
-
33847250946
-
11C-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease
-
DOI 10.1007/s00213-006-0447-7
-
A. Kadir, O. Almkvist, A. Wall, B. Langstrom, and A. Nordberg PET imaging of cortical 11C-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease Psychopharmacology (Berl) 188 2006 509 520 (Pubitemid 46758966)
-
(2006)
Psychopharmacology
, vol.188
, Issue.4
, pp. 509-520
-
-
Kadir, A.1
Almkvist, O.2
Wall, A.3
Langstrom, B.4
Nordberg, A.5
-
100
-
-
0035251750
-
Nicotinic receptor abnormalities in Alzheimer's disease
-
DOI 10.1016/S0006-3223(00)01116-1, PII S0006322300011161
-
J. Court, C. Martin-Ruiz, M. Piggott, D. Spurden, M. Griffiths, and E. Perry Nicotinic receptor abnormalities in Alzheimer's disease Biol Psychiatry 49 2001 175 184 (Pubitemid 32178426)
-
(2001)
Biological Psychiatry
, vol.49
, Issue.3
, pp. 175-184
-
-
Court, J.1
Martin-Ruiz, C.2
Piggott, M.3
Spurden, D.4
Griffiths, M.5
Perry, E.6
-
102
-
-
0037381479
-
1-42
-
DOI 10.1002/neu.10203
-
D.H. Lee, and H.Y. Wang Differential physiologic responses of alpha7 nicotinic acetylcholine receptors to beta-amyloid1-40 and beta-amyloid1-42 J Neurobiol 55 2003 25 30 (Pubitemid 36396959)
-
(2003)
Journal of Neurobiology
, vol.55
, Issue.1
, pp. 25-30
-
-
Lee, D.H.S.1
Wang, H.-Y.2
-
103
-
-
0035875962
-
β-Amyloid activates the mitogen-activated protein kinase cascade via hippocampal α7 nicotinic acetylcholine receptors: In Vitro and in Vivo mechanisms related to Alzheimer's disease
-
K.T. Dineley, M. Westerman, D. Bui, K. Bell, K.H. Ashe, and J.D. Sweatt Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease J Neurosci 21 2001 4125 4133 (Pubitemid 32538537)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.12
, pp. 4125-4133
-
-
Dineley, K.T.1
Westerman, M.2
Bui, D.3
Bell, K.4
Ashe, K.H.5
Sweatt, J.D.6
-
104
-
-
0043135255
-
β-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex
-
J.J. Dougherty, J. Wu, and R.A. Nichols Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex J Neurosci 23 2003 6740 6747 (Pubitemid 36951200)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.17
, pp. 6740-6747
-
-
Dougherty, J.J.1
Wu, J.2
Nichols, R.A.3
-
105
-
-
34249823327
-
The β-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor
-
DOI 10.1111/j.1471-4159.2006.04444.x
-
D.H. Small, D. Maksel, M.L. Kerr, J. Ng, X. Hou, and C. Chu The beta-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the alpha7 nicotinic acetylcholine receptor J Neurochem 101 2007 1527 1538 (Pubitemid 46848846)
-
(2007)
Journal of Neurochemistry
, vol.101
, Issue.6
, pp. 1527-1538
-
-
Small, D.H.1
Maksel, D.2
Kerr, M.L.3
Ng, J.4
Hou, X.5
Chu, C.6
Mehrani, H.7
Unabia, S.8
Azari, M.F.9
Loiacono, R.10
Aguilar, M.-I.11
Chebib, M.12
-
106
-
-
0034006944
-
1-42 binds to α7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology
-
DOI 10.1074/jbc.275.8.5626
-
H.Y. Wang, D.H. Lee, M.R. D'Andrea, P.A. Peterson, R.P. Shank, and A.B. Reitz beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology J Biol Chem 275 2000 5626 5632 (Pubitemid 30115201)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.8
, pp. 5626-5632
-
-
Wang, H.-Y.1
Lee, D.H.S.2
D'Andrea, M.R.3
Peterson, P.A.4
Shank, R.P.5
Reitz, A.B.6
-
107
-
-
0033624509
-
1-42 binds selectively and with picomolar affinity to α7 nicotinic acetylcholine receptors
-
DOI 10.1046/j.1471-4159.2000.0751155.x
-
H.Y. Wang, D.H. Lee, C.B. Davis, and R.P. Shank Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors J Neurochem 75 2000 1155 1161 (Pubitemid 30660505)
-
(2000)
Journal of Neurochemistry
, vol.75
, Issue.3
, pp. 1155-1161
-
-
Wang, H.-Y.1
Lee, D.H.S.2
Davis, C.B.3
Shank, R.P.4
-
108
-
-
67650484613
-
Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease
-
G. Dziewczapolski, C.M. Glogowski, E. Masliah, and S.F. Heinemann Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease J Neurosci 29 2009 8805 8815
-
(2009)
J Neurosci
, vol.29
, pp. 8805-8815
-
-
Dziewczapolski, G.1
Glogowski, C.M.2
Masliah, E.3
Heinemann, S.F.4
-
109
-
-
63849213473
-
Nicotinic acetylcholine receptor signalling: Roles in Alzheimer's disease and amyloid neuroprotection
-
S.D. Buckingham, A.K. Jones, L.A. Brown, and D.B. Sattelle Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection Pharmacol Rev 61 2009 39 61
-
(2009)
Pharmacol Rev
, vol.61
, pp. 39-61
-
-
Buckingham, S.D.1
Jones, A.K.2
Brown, L.A.3
Sattelle, D.B.4
-
110
-
-
0035957946
-
Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
-
T. Kihara, S. Shimohama, H. Sawada, K. Honda, T. Nakamizo, and H. Shibasaki alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity J Biol Chem 276 2001 13541 13546
-
(2001)
J Biol Chem
, vol.276
, pp. 13541-13546
-
-
Kihara, T.1
Shimohama, S.2
Sawada, H.3
Honda, K.4
Nakamizo, T.5
Shibasaki, H.6
-
111
-
-
33846029827
-
Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model
-
DOI 10.1096/fj.06-5841com
-
Q. Liu, J. Zhang, H. Zhu, C. Qin, Q. Chen, and B. Zhao Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model FASEB J 21 2007 61 73 (Pubitemid 46052545)
-
(2007)
FASEB Journal
, vol.21
, Issue.1
, pp. 61-73
-
-
Liu, Q.1
Zhang, J.2
Zhu, H.3
Qin, C.4
Chen, Q.5
Zhao, B.6
-
112
-
-
0032498950
-
Neuroprotective effects of 2,4-dimethoxybenzylidene anabaseine (DMXB) and tetrahydroaminoacridine (THA) in neocortices of nucleus basalis lesioned rats
-
DOI 10.1016/S0006-8993(97)00300-4, PII S0006899397003004
-
E.M. Meyer, M.A. King, and C. Meyers Neuroprotective effects of 2,4-dimethoxybenzylidene anabaseine (DMXB) and tetrahydroaminoacridine (THA) in neocortices of nucleus basalis lesioned rats Brain Res 786 1998 252 254 (Pubitemid 28191740)
-
(1998)
Brain Research
, vol.786
, Issue.1-2
, pp. 252-254
-
-
Meyer, E.M.1
King, M.A.2
Meyers, C.3
-
113
-
-
77952360311
-
DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-)) injected mice through preventing the dysfunction of alpha7 nicotinic receptor
-
L. Chen, H. Wang, Z. Zhang, Z. Li, D. He, and M. Sokabe DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-)) injected mice through preventing the dysfunction of alpha7 nicotinic receptor J Neurosci Res 88 2010 1784 1794
-
(2010)
J Neurosci Res
, vol.88
, pp. 1784-1794
-
-
Chen, L.1
Wang, H.2
Zhang, Z.3
Li, Z.4
He, D.5
Sokabe, M.6
-
114
-
-
62949084265
-
Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo
-
R.S. Bitner, A.L. Nikkel, S. Markosyan, S. Otte, P. Puttfarcken, and M. Gopalakrishnan Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo Brain Res 1265 2009 65 74
-
(2009)
Brain Res
, vol.1265
, pp. 65-74
-
-
Bitner, R.S.1
Nikkel, A.L.2
Markosyan, S.3
Otte, S.4
Puttfarcken, P.5
Gopalakrishnan, M.6
-
115
-
-
80052023127
-
EVP-6124 safety, tolerability and cognitive effects of a novel alpha7 nicotinic receptor agonist in Alzheimer's disease patients on stable donepezil or rivastigmine therapy
-
Vienna, Austria
-
D. Hilt, B. Safirstein, D. Hassman, J. Apter, S. Thein, and P. Maruff EVP-6124 safety, tolerability and cognitive effects of a novel alpha7 nicotinic receptor agonist in Alzheimer's disease patients on stable donepezil or rivastigmine therapy International Congress on Alzheimer's Disease Vienna, Austria 2009
-
(2009)
International Congress on Alzheimer's Disease
-
-
Hilt, D.1
Safirstein, B.2
Hassman, D.3
Apter, J.4
Thein, S.5
Maruff, P.6
-
116
-
-
0030745593
-
Is it possible to be schizophrenic yet neuropsychologically normal?
-
DOI 10.1037/0894-4105.11.3.437
-
B.W. Palmer, R.K. Heaton, J.S. Paulsen, J. Kuck, D. Braff, and M.J. Harris Is it possible to be schizophrenic yet neuropsychologically normal? Neuropsychology 11 1997 437 446 (Pubitemid 27294667)
-
(1997)
Neuropsychology
, vol.11
, Issue.3
, pp. 437-446
-
-
Palmer, B.W.1
Heaton, R.K.2
Kuck, J.3
Braff, D.4
Paulsen, J.S.5
Jackuelyn Harris, M.6
Zisook, S.7
Jeste, D.V.8
-
117
-
-
4444220908
-
Approaching a consensus cognitive battery for clinical trials in schizophrenia: The NIMH-MATRICS conference to select cognitive domains and test criteria
-
DOI 10.1016/j.biopsych.2004.06.023, PII S0006322304007012
-
M.F. Green, K.H. Nuechterlein, J.M. Gold, D.M. Barch, J. Cohen, and S. Essock Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria Biol Psychiatry 56 2004 301 307 (Pubitemid 39164514)
-
(2004)
Biological Psychiatry
, vol.56
, Issue.5
, pp. 301-307
-
-
Green, M.F.1
Nuechterlein, K.H.2
Gold, J.M.3
Barch, D.M.4
Cohen, J.5
Essock, S.6
Fenton, W.S.7
Frese, F.8
Goldberg, T.E.9
Heaton, R.K.10
Keefe, R.S.E.11
Kern, R.S.12
Kraemer, H.13
Stover, E.14
Weinberger, D.R.15
Zalcman, S.16
Marder, S.R.17
-
118
-
-
34548321168
-
Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia
-
DOI 10.1093/schbul/sbm083
-
R.W. Buchanan, R. Freedman, D.C. Javitt, A. Abi-Dargham, and J.A. Lieberman Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia Schizophr Bull 33 2007 1120 1130 (Pubitemid 47347922)
-
(2007)
Schizophrenia Bulletin
, vol.33
, Issue.5
, pp. 1120-1130
-
-
Buchanan, R.W.1
Freedman, R.2
Javitt, D.C.3
Abi-Dargham, A.4
Lieberman, J.A.5
-
119
-
-
0030297344
-
Nicotine-haloperidol interactions and cognitive performance in schizophrenics
-
DOI 10.1016/S0893-133X(96)00018-8, PII S0893133X9600018X
-
E.D. Levin, W. Wilson, J.E. Rose, and J. McEvoy Nicotine-haloperidol interactions and cognitive performance in schizophrenics Neuropsychopharmacology 15 1996 429 436 (Pubitemid 26389866)
-
(1996)
Neuropsychopharmacology
, vol.15
, Issue.5
, pp. 429-436
-
-
Levin, E.D.1
Wilson, W.2
Rose, J.E.3
McEvoy, J.4
-
120
-
-
0027380988
-
Normalization of auditory physiology by cigarette smoking in schizophrenic patients
-
L.E. Adler, L.D. Hoffer, A. Wiser, and R. Freedman Normalization of auditory physiology by cigarette smoking in schizophrenic patients Am J Psychiatry 150 1993 1856 1861 (Pubitemid 23356580)
-
(1993)
American Journal of Psychiatry
, vol.150
, Issue.12
, pp. 1856-1861
-
-
Adler, L.E.1
Hoffer, L.D.2
Wiser, A.3
Freedman, R.4
-
121
-
-
0029085870
-
Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
-
R. Freedman, M. Hall, L.E. Adler, and S. Leonard Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia Biol Psychiatry 38 1995 22 33
-
(1995)
Biol Psychiatry
, vol.38
, pp. 22-33
-
-
Freedman, R.1
Hall, M.2
Adler, L.E.3
Leonard, S.4
-
122
-
-
0031751031
-
Schizophrenia, sensory gating, and nicotinic receptors
-
L.E. Adler, A. Olincy, M. Waldo, J.G. Harris, J. Griffith, and K. Stevens Schizophrenia, sensory gating, and nicotinic receptors Schizophr Bull 24 1998 189 202 (Pubitemid 28404980)
-
(1998)
Schizophrenia Bulletin
, vol.24
, Issue.2
, pp. 189-202
-
-
Adler, L.E.1
Olincy, A.2
Waldo, M.3
Harris, J.G.4
Griffith, J.5
Stevens, K.6
Flach, K.7
Nagamoto, H.8
Bickford, P.9
Leonard, S.10
Freedman, R.11
-
123
-
-
12644303225
-
Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus
-
DOI 10.1073/pnas.94.2.587
-
R. Freedman, H. Coon, M. Myles-Worsley, A. Orr-Urtreger, A. Olincy, and A. Davis Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus Proc Natl Acad Sci USA 94 1997 587 592 (Pubitemid 27053677)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.2
, pp. 587-592
-
-
Freedman, R.1
Coon, H.2
Myles-Worsley, M.3
Orr-Urtreger, A.4
Olincy, A.5
Davis, A.6
Polymeropoulos, M.7
Holik, J.8
Hopkins, J.9
Hoff, M.10
Rosenthal, J.11
Waldo, M.C.12
Reimherr, F.13
Wender, P.14
Yaw, J.15
Young, D.A.16
Breese, C.R.17
Adams, C.18
Patterson, D.19
Adler, L.E.20
Kruglyak, L.21
Leonard, S.22
Byerley, W.23
more..
-
124
-
-
0033574504
-
No evidence for linkage between schizophrenia and markers at chromosome 15q13-14
-
DOI 10.1002/(SICI)1096-8628(19990416)88:2<109::AID-AJMG1>3.0.CO;2-3
-
L. Curtis, J.L. Blouin, U. Radhakrishna, C. Gehrig, V.K. Lasseter, and P. Wolyniec No evidence for linkage between schizophrenia and markers at chromosome 15q13-14 Am J Med Genet 88 1999 109 112 (Pubitemid 29156443)
-
(1999)
American Journal of Medical Genetics - Neuropsychiatric Genetics
, vol.88
, Issue.2
, pp. 109-112
-
-
Curtis, L.1
Blouin, J.-L.2
Radhakrishna, U.3
Gehrig, C.4
Lasseter, V.K.5
Wolyniec, P.6
Nestadt, G.7
Dombroski, B.8
Kazazian, H.H.9
Pulver, A.E.10
Housman, D.11
Bertrand, D.12
Antonarakis, S.E.13
-
125
-
-
0036897309
-
Association of promoter variants in the α7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia
-
DOI 10.1001/archpsyc.59.12.1085
-
S. Leonard, J. Gault, J. Hopkins, J. Logel, R. Vianzon, and M. Short Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia Arch Gen Psychiatry 59 2002 1085 1096 (Pubitemid 35424018)
-
(2002)
Archives of General Psychiatry
, vol.59
, Issue.12
, pp. 1085-1096
-
-
Leonard, S.1
Gault, J.2
Hopkins, J.3
Logel, J.4
Vianzon, R.5
Short, M.6
Drebing, C.7
Berger, R.8
Venn, D.9
Sirota, P.10
Zerbe, G.11
Olincy, A.12
Ross, R.G.13
Adler, L.E.14
Freedman, R.15
-
127
-
-
77954611225
-
A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia
-
A. Shiina, Y. Shirayama, T. Niitsu, T. Hashimoto, T. Yoshida, and T. Hasegawa A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia Ann Gen Psychiatry 9 2010 27
-
(2010)
Ann Gen Psychiatry
, vol.9
, pp. 27
-
-
Shiina, A.1
Shirayama, Y.2
Niitsu, T.3
Hashimoto, T.4
Yoshida, T.5
Hasegawa, T.6
-
128
-
-
33744911665
-
Proof-of-concept trial of an α7 nicotinic agonist in schizophrenia
-
DOI 10.1001/archpsyc.63.6.630
-
A. Olincy, J.G. Harris, L.L. Johnson, V. Pender, S. Kongs, and D. Allensworth Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia Arch Gen Psychiatry 63 2006 630 638 (Pubitemid 43848294)
-
(2006)
Archives of General Psychiatry
, vol.63
, Issue.6
, pp. 630-638
-
-
Olincy, A.1
Harris, J.G.2
Johnson, L.L.3
Pender, V.4
Kongs, S.5
Allensworth, D.6
Ellis, J.7
Zerbe, G.O.8
Leonard, S.9
Stevens, K.E.10
Stevens, J.O.11
Martin, L.12
Adler, L.E.13
Soti, F.14
Kem, W.R.15
Freedman, R.16
-
129
-
-
48949099564
-
Initial phase 2 trial of a nicotinic agonist in schizophrenia
-
R. Freedman, A. Olincy, R.W. Buchanan, J.G. Harris, J.M. Gold, and L. Johnson Initial phase 2 trial of a nicotinic agonist in schizophrenia Am J Psychiatry 165 2008 1040 1047
-
(2008)
Am J Psychiatry
, vol.165
, pp. 1040-1047
-
-
Freedman, R.1
Olincy, A.2
Buchanan, R.W.3
Harris, J.G.4
Gold, J.M.5
Johnson, L.6
-
130
-
-
78650762669
-
The effect of the partial nicotinic alpha7 receptor agonist R3487 on cognitive deficits in schizophrenia
-
Hollywood, Florida
-
D.M.S. Umbricht, D. Lowe, K. Yoo, R. Porter, G. Garibaldi, and L. Santarelli The effect of the partial nicotinic alpha7 receptor agonist R3487 on cognitive deficits in schizophrenia 48th annual meeting of American college of neuropsychopharmacology Hollywood, Florida 2009
-
(2009)
48th Annual Meeting of American College of Neuropsychopharmacology
-
-
Umbricht, D.M.S.1
Lowe, D.2
Yoo, K.3
Porter, R.4
Garibaldi, G.5
Santarelli, L.6
-
131
-
-
80052024271
-
The alpha7 neuronal nicotinic receptor (NNR) agonist TC-5619 had beneficial effects and was generally well tolerated in a phase 2 trial in cognitive dysfunction in schizophrenia (CDS)
-
Colorado Springs, Colorado, USA
-
D. Hosford, G. Dunbar, J.A. Lieberman, and A. Segreti The alpha7 neuronal nicotinic receptor (NNR) agonist TC-5619 had beneficial effects and was generally well tolerated in a phase 2 trial in cognitive dysfunction in schizophrenia (CDS) 13th international congress on schizophrenia research Colorado Springs, Colorado, USA 2011
-
(2011)
13th International Congress on Schizophrenia Research
-
-
Hosford, D.1
Dunbar, G.2
Lieberman, J.A.3
Segreti, A.4
-
132
-
-
0004235298
-
-
A.P. Association 4th ed. American Psychiatric Association Washington, DC
-
A.P. Association Diagnostic and statistical manual of mental disorders 4th ed. 1994 American Psychiatric Association Washington, DC
-
(1994)
Diagnostic and Statistical Manual of Mental Disorders
-
-
-
133
-
-
0031928549
-
Nicotinic acetylcholine involvement in cogitive function in animals
-
DOI 10.1007/s002130050667
-
E.D. Levin, and B.B. Simon Nicotinic acetylcholine involvement in cognitive function in animals Psychopharmacology (Berl) 138 1998 217 230 (Pubitemid 28365487)
-
(1998)
Psychopharmacology
, vol.138
, Issue.3-4
, pp. 217-230
-
-
Levin, E.D.1
Simon, B.B.2
-
134
-
-
0029595433
-
Cigarette smoking in adult patients diagnosed with attention deficit hyperactivity disorder
-
DOI 10.1016/0899-3289(95)90030-6
-
O.F. Pomerleau, K.K. Downey, F.W. Stelson, and C.S. Pomerleau Cigarette
-
(1995)
Journal of Substance Abuse
, vol.7
, Issue.3
, pp. 373-378
-
-
Pomerleau, O.F.1
Downey, K.K.2
Stelson, F.W.3
Pomerleau, C.S.4
-
135
-
-
0030737908
-
Further evidence of an association between attention- deficit/hyperactivity disorder and cigarette smoking: Findings from a high- risk sample of siblings
-
S. Milberger, J. Biederman, S.V. Faraone, L. Chen, and J. Jones Further evidence of an association between attention-deficit/hyperactivity disorder and cigarette smoking Findings from a high-risk sample of siblings Am J Addict 6 1997 205 217 (Pubitemid 27356003)
-
(1997)
American Journal on Addictions
, vol.6
, Issue.3
, pp. 205-217
-
-
Milberger, S.1
Biederman, J.2
Faraone, S.V.3
Chen, L.4
Jones, J.5
-
136
-
-
0029767702
-
Is maternal smoking during pregnancy a risk factor for attention deficit hyperactivity disorder in children?
-
S. Milberger, J. Biederman, S.V. Faraone, L. Chen, and J. Jones Is maternal smoking during pregnancy a risk factor for attention deficit hyperactivity disorder in children? Am J Psychiatry 153 1996 1138 1142 (Pubitemid 26299831)
-
(1996)
American Journal of Psychiatry
, vol.153
, Issue.9
, pp. 1138-1142
-
-
Milberger, S.1
Biederman, J.2
Faraone, S.V.3
Chen, L.4
Jones, J.5
-
137
-
-
0035829966
-
No association between CHRNA7 microsatellite markers and attention-deficit hyperactivity disorder
-
DOI 10.1002/ajmg.1553
-
L. Kent, E. Green, J. Holmes, A. Thapar, M. Gill, and Z. Hawi No association between CHRNA7 microsatellite markers and attention-deficit hyperactivity disorder Am J Med Genet 105 2001 686 689 (Pubitemid 33101467)
-
(2001)
American Journal of Medical Genetics - Neuropsychiatric Genetics
, vol.105
, Issue.8
, pp. 686-689
-
-
Kent, L.1
Green, E.2
Holmes, J.3
Thapar, A.4
Gill, M.5
Hawi, Z.6
Fitzgerald, M.7
Asherson, P.8
Curran, S.9
Mills, J.10
Payton, A.11
Craddock, N.12
-
138
-
-
0034946403
-
Cholinergic activity in autism: Abnormalities in the cerebral cortex and basal forebrain
-
DOI 10.1176/appi.ajp.158.7.1058
-
E.K. Perry, M.L. Lee, C.M. Martin-Ruiz, J.A. Court, S.G. Volsen, and J. Merrit Cholinergic activity in autism: abnormalities in the cerebral cortex and basal forebrain Am J Psychiatry 158 2001 1058 1066 (Pubitemid 32623109)
-
(2001)
American Journal of Psychiatry
, vol.158
, Issue.7
, pp. 1058-1066
-
-
Perry, E.K.1
Lee, M.L.W.2
Martin-Ruiz, C.M.3
Court, J.A.4
Volsen, S.G.5
Merrit, J.6
Folly, E.7
Iversen, P.E.8
Bauman, M.L.9
Perry, R.H.10
Wenk, G.L.11
-
139
-
-
77953150437
-
Cholinergic abnormalities in autism: Is there a rationale for selective nicotinic agonist interventions?
-
S.I. Deutsch, M.R. Urbano, S.R. Neumann, J.A. Burket, and E. Katz Cholinergic abnormalities in autism: is there a rationale for selective nicotinic agonist interventions? Clin Neuropharmacol 33 2010 114 120
-
(2010)
Clin Neuropharmacol
, vol.33
, pp. 114-120
-
-
Deutsch, S.I.1
Urbano, M.R.2
Neumann, S.R.3
Burket, J.A.4
Katz, E.5
-
141
-
-
0036310086
-
Nicotinic receptor abnormalities in the cerebellar cortex in autism
-
M. Lee, C. Martin-Ruiz, A. Graham, J. Court, E. Jaros, and R. Perry Nicotinic receptor abnormalities in the cerebellar cortex in autism Brain 125 2002 1483 1495 (Pubitemid 34755164)
-
(2002)
Brain
, vol.125
, Issue.7
, pp. 1483-1495
-
-
Lee, M.1
Martin-Ruiz, C.2
Graham, A.3
Court, J.4
Jaros, E.5
Perry, R.6
Iversen, P.7
Bauman, M.8
Perry, E.9
-
142
-
-
0036310203
-
Brain anatomy and sensorimotor gating in Asperger's syndrome
-
G.M. McAlonan, E. Daly, V. Kumari, H.D. Critchley, T. van Amelsvoort, and J. Suckling Brain anatomy and sensorimotor gating in Asperger's syndrome Brain 125 2002 1594 1606 (Pubitemid 34755173)
-
(2002)
Brain
, vol.125
, Issue.7
, pp. 1594-1606
-
-
McAlonan, G.M.1
Daly, E.2
Kumari, V.3
Critchley, H.D.4
Van Amelsvoort, T.5
Suckling, J.6
Simmons, A.7
Sigmundsson, T.8
Greenwood, K.9
Russell, A.10
Schmitz, N.11
Happe, F.12
Howlin, P.13
Murphy, D.G.M.14
-
143
-
-
40849107718
-
Sensory gating in young children with autism: Relation to age IQ, and EEG gamma oscillations
-
E.V. Orekhova, T.A. Stroganova, A.O. Prokofyev, G. Nygren, C. Gillberg, and M. Elam Sensory gating in young children with autism: relation to age IQ, and EEG gamma oscillations Neurosci Lett 434 2008 218 223
-
(2008)
Neurosci Lett
, vol.434
, pp. 218-223
-
-
Orekhova, E.V.1
Stroganova, T.A.2
Prokofyev, A.O.3
Nygren, G.4
Gillberg, C.5
Elam, M.6
-
144
-
-
34548683244
-
Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys
-
DOI 10.1016/j.bcp.2007.07.010, PII S0006295207004625
-
J.J. Buccafusco, A.V. Terry Jr., M.W. Decker, and M. Gopalakrishnan Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys Biochem Pharmacol 74 2007 1202 1211 (Pubitemid 47417930)
-
(2007)
Biochemical Pharmacology
, vol.74
, Issue.8
, pp. 1202-1211
-
-
Buccafusco, J.J.1
Terry Jr., A.V.2
Decker, M.W.3
Gopalakrishnan, M.4
-
145
-
-
57349165705
-
Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice
-
J.P. Redrobe, E.O. Nielsen, J.K. Christensen, D. Peters, D.B. Timmermann, and G.M. Olsen Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice Eur J Pharmacol 602 2009 58 65
-
(2009)
Eur J Pharmacol
, vol.602
, pp. 58-65
-
-
Redrobe, J.P.1
Nielsen, E.O.2
Christensen, J.K.3
Peters, D.4
Timmermann, D.B.5
Olsen, G.M.6
-
146
-
-
34247184782
-
The novel α7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2- carboxamide improves working and recognition memory in rodents
-
DOI 10.1124/jpet.106.118976
-
F.G. Boess, J. De Vry, C. Erb, T. Flessner, M. Hendrix, and J. Luithle The novel alpha7 nicotinic acetylcholine receptor agonist N-[(3R)-1- azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide improves working and recognition memory in rodents J Pharmacol Exp Ther 321 2007 716 725 (Pubitemid 46624485)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.2
, pp. 716-725
-
-
Boess, F.G.1
De Vry, J.2
Erb, C.3
Flessner, T.4
Hendrix, M.5
Luithle, J.6
Methfessel, C.7
Riedl, B.8
Schnizler, K.9
Van Der Staay, F.-J.10
Van Kampen, M.11
Wiese, W.B.12
Koenig, G.13
-
147
-
-
2442591453
-
7 receptors
-
DOI 10.1007/s00213-003-1668-7
-
M. Van Kampen, K. Selbach, R. Schneider, E. Schiegel, F. Boess, and R. Schreiber AR-R 17779 improves social recognition in rats by activation of nicotinic alpha7 receptors Psychopharmacology (Berl) 172 2004 375 383 (Pubitemid 38650972)
-
(2004)
Psychopharmacology
, vol.172
, Issue.4
, pp. 375-383
-
-
Van Kampen, M.1
Selbach, K.2
Schneider, R.3
Schiegel, E.4
Boess, F.5
Schreiber, R.6
-
148
-
-
53949092571
-
Nicotinic acetylcholine receptors and modulation of learning in 4- and 27-month-old rabbits
-
J.G. Li, M. Lehr, L.Y. Liu-Chen, and D.S. Woodruff-Pak Nicotinic acetylcholine receptors and modulation of learning in 4- and 27-month-old rabbits Neuropsychopharmacology 33 2008 2820 2830
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2820-2830
-
-
Li, J.G.1
Lehr, M.2
Liu-Chen, L.Y.3
Woodruff-Pak, D.S.4
-
149
-
-
68349141525
-
Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes
-
S. Sydserff, E.J. Sutton, D. Song, M.C. Quirk, C. Maciag, and C. Li Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes Biochem Pharmacol 78 2009 880 888
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 880-888
-
-
Sydserff, S.1
Sutton, E.J.2
Song, D.3
Quirk, M.C.4
MacIag, C.5
Li, C.6
-
150
-
-
33745872934
-
(R)-3′-(3-methylbenzo[6]thiophen-5-yl)spiro[1-azabicyclo[2,2,2] octane-3,5′-oxazolidin]-2′-one, a novel and potent α7 nicotinic acetylcholine receptor partial agonist displays cognitive enhancing properties
-
DOI 10.1021/jm060249c
-
R. Tatsumi, M. Fujio, S. Takanashi, A. Numata, J. Katayama, and H. Satoh (R)-3′-(3-methylbenzo[b]thiophen-5-yl)spiro[1-azabicyclo[2,2,2]octane-3, 5′-oxazolidin]-2′-one, a novel and potent alpha7 nicotinic acetylcholine receptor partial agonist displays cognitive enhancing properties J Med Chem 49 2006 4374 4383 (Pubitemid 44036681)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.14
, pp. 4374-4383
-
-
Tatsumi, R.1
Fujio, M.2
Takanashi, S.-I.3
Numata, A.4
Katayama, J.5
Satoh, H.6
Shiigi, Y.7
Maeda, J.-I.8
Kuriyama, M.9
Horikawa, T.10
Murozono, T.11
Hashimoto, K.12
Tanaka, H.13
-
151
-
-
0028199608
-
A nicotinic agonist (GTS-21), eyeblink classical conditioning, and nicotinic receptor binding in rabbit brain
-
D.S. Woodruff-Pak, Y.T. Li, and W.R. Kem A nicotinic agonist (GTS-21), eyeblink classical conditioning, and nicotinic receptor binding in rabbit brain Brain Res 645 1994 309 317 (Pubitemid 24140138)
-
(1994)
Brain Research
, vol.645
, Issue.1-2
, pp. 309-317
-
-
Woodruff-Pak, D.S.1
Li, Y.-T.2
Kem, W.R.3
-
152
-
-
0033736632
-
A nicotinic cholinergic agonist (GTS-21) and eyeblink classical conditioning: Acquisition, retention, and relearning in older rabbits
-
D.S. Woodruff-Pak, J.T. Green, C. Coleman-Valencia, and J.T. Pak A nicotinic cholinergic agonist (GTS-21) and eyeblink classical conditioning: acquisition, retention, and relearning in older rabbits Exp Aging Res 26 2000 323 336
-
(2000)
Exp Aging Res
, vol.26
, pp. 323-336
-
-
Woodruff-Pak, D.S.1
Green, J.T.2
Coleman-Valencia, C.3
Pak, J.T.4
-
153
-
-
0042594579
-
Mecamylamine reversal by nicotine and by a partial α7 nicotinic acetylcholine receptor agonist (GTS-21) in rabbits tested with delay eyeblink classical conditioning
-
DOI 10.1016/S0166-4328(03)00039-1
-
D.S. Woodruff-Pak Mecamylamine reversal by nicotine and by a partial alpha7 nicotinic acetylcholine receptor agonist (GTS-21) in rabbits tested with delay eyeblink classical conditioning Behav Brain Res 143 2003 159 167 (Pubitemid 36937161)
-
(2003)
Behavioural Brain Research
, vol.143
, Issue.2
, pp. 159-167
-
-
Woodruff-Pak, D.S.1
-
154
-
-
0028883095
-
Diversity of neuronal nicotinic acetylcholine receptors: Lessons from behavior and implications for CNS therapeutics
-
M.W. Decker, J.D. Brioni, A.W. Bannon, and S.P. Arneric Diversity of neuronal nicotinic acetylcholine receptors: lessons from behavior and implications for CNS therapeutics Life Sci 56 1995 545 570
-
(1995)
Life Sci
, vol.56
, pp. 545-570
-
-
Decker, M.W.1
Brioni, J.D.2
Bannon, A.W.3
Arneric, S.P.4
-
155
-
-
0035470834
-
Intragastric DMXB-A, an α7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice
-
DOI 10.1016/S0006-3223(01)01093-9, PII S0006322301010939
-
J.K. Simosky, K.E. Stevens, W.R. Kem, and R. Freedman Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice Biol Psychiatry 50 2001 493 500 (Pubitemid 32971880)
-
(2001)
Biological Psychiatry
, vol.50
, Issue.7
, pp. 493-500
-
-
Simosky, J.K.1
Stevens, K.E.2
Kem, W.R.3
Freedman, R.4
-
156
-
-
0032753990
-
Selective alpha 7 nicotinic receptor stimulation normalizes chronic cocaine-induced loss of hippocampal sensory inhibition in C3H mice
-
K.E. Stevens, W.R. Kem, and R. Freedman Selective alpha 7 nicotinic receptor stimulation normalizes chronic cocaine-induced loss of hippocampal sensory inhibition in C3H mice Biol Psychiatry 46 1999 1443 1450
-
(1999)
Biol Psychiatry
, vol.46
, pp. 1443-1450
-
-
Stevens, K.E.1
Kem, W.R.2
Freedman, R.3
-
157
-
-
58049109125
-
The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain
-
D. Feuerbach, K. Lingenhoehl, H.R. Olpe, A. Vassout, C. Gentsch, and F. Chaperon The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain Neuropharmacology 56 2009 254 263
-
(2009)
Neuropharmacology
, vol.56
, pp. 254-263
-
-
Feuerbach, D.1
Lingenhoehl, K.2
Olpe, H.R.3
Vassout, A.4
Gentsch, C.5
Chaperon, F.6
-
158
-
-
33745808357
-
Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5- carboxamide, an agonist of the α7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: Synthesis and structure-activity relationship
-
DOI 10.1021/jm0602413
-
D.G. Wishka, D.P. Walker, K.M. Yates, S.C. Reitz, S. Jia, and J.K. Myers Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5- carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure - activity relationship J Med Chem 49 2006 4425 4436 (Pubitemid 44036685)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.14
, pp. 4425-4436
-
-
Wishka, D.G.1
Walker, D.P.2
Yates, K.M.3
Reitz, S.C.4
Jia, S.5
Myers, J.K.6
Olson, K.L.7
Jacobsen, E.J.8
Wolfe, M.L.9
Groppi, V.E.10
Hanchar, A.J.11
Thornburgh, B.A.12
Cortes-Burgos, L.A.13
Wong, E.H.F.14
Staton, B.A.15
Raub, T.J.16
Higdon, N.R.17
Wall, T.M.18
Hurst, R.S.19
Walters, R.R.20
Hoffmann, W.E.21
Hajos, M.22
Franklin, S.23
Carey, G.24
Gold, L.H.25
Cook, K.K.26
Sands, S.B.27
Zhao, S.X.28
Soglia, J.R.29
Kalgutkar, A.S.30
Arneric, S.P.31
Rogers, B.N.32
more..
-
159
-
-
33750532078
-
Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists
-
DOI 10.1016/j.bmc.2006.09.019, PII S0968089606007504
-
D.P. Walker, D.G. Wishka, D.W. Piotrowski, S. Jia, S.C. Reitz, and K.M. Yates Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists Bioorg Med Chem 14 2006 8219 8248 (Pubitemid 44667561)
-
(2006)
Bioorganic and Medicinal Chemistry
, vol.14
, Issue.24
, pp. 8219-8248
-
-
Walker, D.P.1
Wishka, D.G.2
Piotrowski, D.W.3
Jia, S.4
Reitz, S.C.5
Yates, K.M.6
Myers, J.K.7
Vetman, T.N.8
Margolis, B.J.9
Jacobsen, E.J.10
Acker, B.A.11
Groppi, V.E.12
Wolfe, M.L.13
Thornburgh, B.A.14
Tinholt, P.M.15
Cortes-Burgos, L.A.16
Walters, R.R.17
Hester, M.R.18
Seest, E.P.19
Dolak, L.A.20
Han, F.21
Olson, B.A.22
Fitzgerald, L.23
Staton, B.A.24
Raub, T.J.25
Hajos, M.26
Hoffmann, W.E.27
Li, K.S.28
Higdon, N.R.29
Wall, T.M.30
Hurst, R.S.31
Wong, E.H.F.32
Rogers, B.N.33
more..
-
160
-
-
44649098133
-
Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine- 5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo activity
-
DOI 10.1016/j.bmcl.2008.04.070, PII S0960894X08004745
-
B.A. Acker, E.J. Jacobsen, B.N. Rogers, D.G. Wishka, S.C. Reitz, and D.W. Piotrowski Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c] pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity Bioorg Med Chem Lett 18 2008 3611 3615 (Pubitemid 351787553)
-
(2008)
Bioorganic and Medicinal Chemistry Letters
, vol.18
, Issue.12
, pp. 3611-3615
-
-
Acker, B.A.1
Jacobsen, E.J.2
Rogers, B.N.3
Wishka, D.G.4
Reitz, S.C.5
Piotrowski, D.W.6
Myers, J.K.7
Wolfe, M.L.8
Groppi, V.E.9
Thornburgh, B.A.10
Tinholt, P.M.11
Walters, R.R.12
Olson, B.A.13
Fitzgerald, L.14
Staton, B.A.15
Raub, T.J.16
Krause, M.17
Li, K.S.18
Hoffmann, W.E.19
Hajos, M.20
Hurst, R.S.21
Walker, D.P.22
more..
-
161
-
-
34249745752
-
Frontal cortical α7 and α4β2 nicotinic acetylcholine receptors in working and reference memory
-
DOI 10.1016/j.neuropharm.2007.03.008, PII S0028390807000767
-
W.K. Chan, P.T. Wong, and F.S. Sheu Frontal cortical alpha7 and alpha4beta2 nicotinic acetylcholine receptors in working and reference memory Neuropharmacology 52 2007 1641 1649 (Pubitemid 46843139)
-
(2007)
Neuropharmacology
, vol.52
, Issue.8
, pp. 1641-1649
-
-
Chan, W.K.1
Tsun-Hon Wong, P.2
Sheu, F.-S.3
-
162
-
-
13944267447
-
Discovery and structure-activity relationship of quinuclidine benzamides as agonists of α7 nicotinic acetylcholine receptors
-
DOI 10.1021/jm049363q
-
A.L. Bodnar, L.A. Cortes-Burgos, K.K. Cook, D.M. Dinh, V.E. Groppi, and M. Hajos Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors J Med Chem 48 2005 905 908 (Pubitemid 40270435)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.4
, pp. 905-908
-
-
Bodnar, A.L.1
Cortes-Burgos, L.A.2
Cook, K.K.3
Dinh, D.M.4
Groppi, V.E.5
Hajos, M.6
Higdon, N.R.7
Hoffmann, W.E.8
Hurst, R.S.9
Myers, J.K.10
Rogers, B.N.11
Wall, T.M.12
Wolfe, M.L.13
Wong, E.14
-
164
-
-
36849055179
-
Phencyclidine-Induced Cognitive Deficits in Mice Are Improved by Subsequent Subchronic Administration of the Novel Selective α7 Nicotinic Receptor Agonist SSR180711
-
DOI 10.1016/j.biopsych.2007.04.034, PII S0006322307004246, Schizophrenia: From Genetics to Treatment
-
K. Hashimoto, T. Ishima, Y. Fujita, M. Matsuo, T. Kobashi, and M. Takahagi Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective alpha7 nicotinic receptor agonist SSR 180711 Biol Psychiatry 63 2008 92 97 (Pubitemid 350234890)
-
(2008)
Biological Psychiatry
, vol.63
, Issue.1
, pp. 92-97
-
-
Hashimoto, K.1
Ishima, T.2
Fujita, Y.3
Matsuo, M.4
Kobashi, T.5
Takahagi, M.6
Tsukada, H.7
Iyo, M.8
-
165
-
-
67349085106
-
Alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment
-
M.S. Thomsen, D.Z. Christensen, H.H. Hansen, J.P. Redrobe, and J.D. Mikkelsen alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment Neuropharmacology 56 2009 1001 1009
-
(2009)
Neuropharmacology
, vol.56
, pp. 1001-1009
-
-
Thomsen, M.S.1
Christensen, D.Z.2
Hansen, H.H.3
Redrobe, J.P.4
Mikkelsen, J.D.5
-
166
-
-
68349148342
-
TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia
-
T.A. Hauser, A. Kucinski, K.G. Jordan, G.J. Gatto, S.R. Wersinger, and R.A. Hesse TC-5619: an alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia Biochem Pharmacol 78 2009 803 812
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 803-812
-
-
Hauser, T.A.1
Kucinski, A.2
Jordan, K.G.3
Gatto, G.J.4
Wersinger, S.R.5
Hesse, R.A.6
-
167
-
-
66349096318
-
Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl) benzenesulfonami de (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor
-
R. Faghih, S.M. Gopalakrishnan, J.H. Gronlien, J. Malysz, C.A. Briggs, and C. Wetterstrand Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H- pyrrol-1-yl)benzenesulfonami de (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor J Med Chem 52 2009 3377 3384
-
(2009)
J Med Chem
, vol.52
, pp. 3377-3384
-
-
Faghih, R.1
Gopalakrishnan, S.M.2
Gronlien, J.H.3
Malysz, J.4
Briggs, C.A.5
Wetterstrand, C.6
-
168
-
-
26844530147
-
Reversal of isolation-rearing-induced PPI deficits by an α7 nicotinic receptor agonist
-
DOI 10.1007/s00213-005-0069-5
-
J. Cilia, J.E. Cluderay, M.J. Robbins, C. Reavill, E. Southam, and J.N. Kew Reversal of isolation-rearing-induced PPI deficits by an alpha7 nicotinic receptor agonist Psychopharmacology (Berl) 182 2005 214 219 (Pubitemid 41464614)
-
(2005)
Psychopharmacology
, vol.182
, Issue.2
, pp. 214-219
-
-
Cilia, J.1
Cluderay, J.E.2
Robbins, M.J.3
Reavill, C.4
Southam, E.5
Kew, J.N.C.6
Jones, D.N.C.7
|