The novel α7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2- carboxamide improves working and recognition memory in rodents

Journal of Pharmacology and Experimental Therapeutics

Volumn 321, Issue 2, 2007, Pages 716-725

  Boess, Frank G ^a,d   De Vry, Jean ^a,e   Erb, Christina ^a,f   Flessner, Timo ^a   Hendrix, Martin ^a   Luithle, Joachim ^a   Methfessel, Christoph ^c   Riedl, Bernd ^a   Schnizler, Katrin ^c,g   Van Der Staay, Franz Josef ^a,h   Van Kampen, Marja ^a,i   Wiese, Welf Burkhard ^b   Koenig, Gerhard ^a,j  

^a BAYER PHARMA AG   (Germany)

^b BAYER CROPSCIENCE AG   (Germany)

^c BAYER AG   (Germany)

^d ELI LILLY AND COMPANY   (United States)

^e GRÜNENTHAL GMBH   (Germany)

^f MERZ PHARMACEUTICALS GMBH   (Germany)

^g UNIVERSITY OF IOWA   (United States)

^h WAGENINGEN UNIVERSITY   (Netherlands)

ⁱ Schwarz Pharma AG   (Germany)

^j EnVivo Pharmaceuticals   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN RECEPTOR; METHYLLYCACONITINE; N [1 AZABICYCLO[2.2.2]OCT 3 YL] 7 [2 (METHOXY)PHENYL] 1 BENZOFURAN 2 CARBOXAMIDE; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; PROTEIN ALPHA3BETA4 NICOTINIC RECEPTOR; PROTEIN ALPHA4BETA2 NICOTINIC RECEPTOR; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG; ALPHA-BUNGAROTOXIN RECEPTOR; BENZOFURAN DERIVATIVE; FUSED HETEROCYCLIC RINGS; N (1 AZABICYCLO(2.2.2)OCT 3 YL) 7 (2 (METHOXY)PHENYL) 1 BENZOFURAN 2 CARBOXAMIDE; N-(1-AZABICYCLO(2.2.2)OCT-3-YL)-7-(2-(METHOXY)PHENYL)-1-BENZOFURAN-2-CARBOXAMIDE; QUINUCLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG DISCRIMINATION; DRUG RECEPTOR BINDING; MALE; MAZE TEST; MEMORY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; RECOGNITION; WORKING MEMORY; XENOPUS; ANIMAL; BROWN NORWAY RAT; COGNITIVE DEFECT; DRUG EFFECT; EXPLORATORY BEHAVIOR; FISCHER 344 RAT; LEARNING; MOUSE; WISTAR RAT;

ANIMALS; BENZOFURANS; BICYCLO COMPOUNDS, HETEROCYCLIC; COGNITION DISORDERS; EXPLORATORY BEHAVIOR; GENERALIZATION (PSYCHOLOGY); MALE; MAZE LEARNING; MEMORY; MICE; NICOTINIC AGONISTS; QUINUCLIDINES; RATS; RATS, INBRED BN; RATS, INBRED F344; RATS, WISTAR; RECEPTORS, NICOTINIC;

EID: 34247184782     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.118976     Document Type: Article

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