Deletion of the α7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease

Journal of Neuroscience

Volumn 29, Issue 27, 2009, Pages 8805-8815

  Dziewczapolski, Gustavo ^a   Glogowski, Carolina M ^a   Masliah, Eliezer ^b,c   Heinemann, Stephen F ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BUNGAROTOXIN RECEPTOR; SYNAPTOPHYSIN;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR GENE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN PROTECTION; COGNITIVE DEFECT; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED STUDY; EXPERIMENTAL MODEL; FEMALE; GENE; GENE EXPRESSION; GENE MUTATION; GLIOSIS; LEARNING; LONG TERM POTENTIATION; MALE; MAZE TEST; MEMORY; MOUSE; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PATHOLOGY; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; GENE DELETION; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, NICOTINIC; SERUM AMYLOID A PROTEIN; SYNAPSES;

EID: 67650484613     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6159-08.2009     Document Type: Article

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