Nicotinic acetylcholine receptors and the regulation of neuronal signalling

Trends in Pharmacological Sciences

Volumn 25, Issue 6, 2004, Pages 317-324

  Dajas Bailador, Federico ^a   Wonnacott, Susan ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTRANSMITTER; NICOTINIC RECEPTOR;

CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL DEATH; COGNITION; DRUG DEPENDENCE; EXPERIMENTAL MODEL; GENE EXPRESSION; HUMAN; MEMORY; MOLECULAR DYNAMICS; NERVE CELL; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PERMEABILITY; PLASTICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; REWARD; SIGNAL TRANSDUCTION; SUBSTANCE ABUSE;

ANIMALS; HUMANS; NEURONS; RECEPTORS, NICOTINIC; REWARD; SIGNAL TRANSDUCTION; SUBSTANCE-RELATED DISORDERS;

EID: 2542486433     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2004.04.006     Document Type: Review

References (96)

1. Miyazawa A., et al. Structure and gating mechanism of the acetylcholine receptor pore. Nature. 424:2003;949-955
2. Fenster C.P., et al. Influence of subunit composition on desensitization of neuronal acetylcholine receptors at low concentrations of nicotine. J. Neurosci. 17:1997;5747-5759
3. Nai Q., et al. Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit composition and channel function. Mol. Pharmacol. 63:2003;311-324
4. Frazier C.J., et al. Synaptic potentials mediated via α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons. J. Neurosci. 18:1998;8228-8235
5. Alkondon M., et al. α-bungarotoxin- and methyllycaconitine- sensitive nicotinic receptors mediate fast synaptic transmission in interneurons of rat hippocampal slices. Brain Res. 810:1998;257-263
6. Role L.W., Berg D.K. Nicotinic receptors in the development and modulation of CNS synapses. Neuron. 16:1996;1077-1085
7. 2+ permeability of nicotinic acetylcholine receptors. Cell Calcium. 35:2004;1-8
8. 2+ modulation of human neuronal α3 nicotinic receptors. J. Pharmacol. Exp. Ther. 286:1998;311-320
9. 2+ current through human neuronal α7 nicotinic acetylcholine receptors. Cell Calcium. 34:2003;205-209
10. Burnashev N., et al. Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes. J. Physiol. 485:1995;403-418
11. 2+ permeability in recombinant glutamate receptor subtypes. J. Physiol. 538:2002;25-39
12. Rathouz M.M., Berg D.K. Synaptic-type acetylcholine receptors raise intracellular calcium levels in neurons by two mechanisms. J. Neurosci. 14:1994;6935-6945
13. 2+ stores. J. Neurochem. 81:2002;606-614
14. Mulle C., et al. Calcium influx through nicotinic receptor in rat central neurons: its relevance to cellular regulation. Neuron. 8:1992;135-143
15. Berridge M.J., et al. Calcium signalling: dynamics, homeostasis and remodelling. Nat. Rev. Mol. Cell Biol. 4:2003;517-529
16. Brain K.L., et al. Nicotine induces calcium spikes in single nerve terminal varicosities: a role for intracellular calcium stores. Neuroscience. 106:2001;395-403
17. Tsuneki H., et al. Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta. Eur. J. Neurosci. 12:2000;2475-2485
18. Shoop R.D., et al. Synaptically driven calcium transients via nicotinic receptors on somatic spines. J. Neurosci. 21:2001;771-781
19. 2+ in rat intracardiac ganglion neurons. J. Neurophysiol. 90:2003;1956-1964
20. Barrantes G.E., et al. Nicotine increases intracellular calcium in rat hippocampal neurons via voltage-gated calcium channels. Neurosci. Lett. 196:1995;101-104
21. 2+. Neuron. 8:1992;353-362
22. Sharma G., Vijayaraghavan S. Nicotinic cholinergic signaling in hippocampal astrocytes involves calcium-induced calcium release from intracellular stores. Proc. Natl. Acad. Sci. U. S. A. 98:2001;4148-4153
23. Giovannelli A., et al. Acetylcholine induces voltage-independent increase of cytosolic calcium in mouse myotubes. Proc. Natl. Acad. Sci. U. S. A. 88:1991;10069-10073
24. Gueorguiev V.D., et al. Involvement of α7 nicotinic acetylcholine receptors in activation of tyrosine hydroxylase and dopamine β-hydroxylase gene expression in PC12 cells. J. Neurochem. 75:2000;1997-2005
25. Eberhard D.A., Holz R.W. Cholinergic stimulation of inositol phosphate formation in bovine adrenal chromaffin cells: distinct nicotinic and muscarinic mechanisms. J. Neurochem. 49:1987;1634-1643
26. 2+ release channels. Proc. Natl. Acad. Sci. U. S. A. 99:2002;7711-7716
27. Quick M.W., Lester R.A. Desensitization of neuronal nicotinic receptors. J. Neurobiol. 53:2002;457-478
28. 2+ regulation of nicotinic acetylcholine receptor channels in rat hippocampal CA1 neurons. J. Neurosci. 23:2003;9024-9031
29. Ullian E.M., et al. Rapid synaptic transmission in the avian ciliary ganglion is mediated by two distinct classes of nicotinic receptors. J. Neurosci. 17:1997;7210-7219
30. Zhang Z.W., et al. Synaptic currents generated by neuronal acetylcholine receptors sensitive to α-bungarotoxin. Neuron. 17:1996;1231-1240
31. Wonnacott S. Presynaptic nicotinic ACh receptors. Trends Neurosci. 20:1997;92-98
32. 2+ ions in nicotinic facilitation of GABA release in mouse thalamus. J. Neurosci. 17:1997;576-585
33. Roerig B., et al. Fast synaptic signaling by nicotinic acetylcholine and serotonin 5-HT3 receptors in developing visual cortex. J. Neurosci. 17:1997;8353-8362
34. Fabian-Fine R., et al. Ultrastructural distribution of the α7 nicotinic acetylcholine receptor subunit in rat hippocampus. J. Neurosci. 21:2001;7993-8003
35. Zoli M., et al. Identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum. J. Neurosci. 22:2002;8785-8789
36. 3H]dopamine release from rat striatal synaptosomes. J. Neurochem. 67:1996;163-170
37. Kulak J.M., et al. Nicotine-evoked transmitter release from synaptosomes: functional association of specific presynaptic acetylcholine receptors and voltage-gated calcium channels. J. Neurochem. 77:2001;1581-1589
38. Gray R., et al. Hippocampal synaptic transmission enhanced by low concentrations of nicotine. Nature. 383:1996;713-716
39. Sharma G., Vijayaraghavan S. Modulation of presynaptic store calcium induces release of glutamate and postsynaptic firing. Neuron. 38:2003;929-939
40. Otsu Y., Murphy T.H. Miniature transmitter release: accident of nature or careful design? Sci. STKE. 2003:2003;e54
41. Soliakov L., Wonnacott S. Involvement of protein kinase C in the presynaptic nicotinic modulation of. Br. J. Pharmacol. 132:2001;785-791
42. Cox M.E., Parsons S.J. Roles for protein kinase C and mitogen-activated protein kinase in nicotine-induced secretion from bovine adrenal chromaffin cells. J. Neurochem. 69:1997;1119-1130
43. Delouche B., et al. Phosphorylation by protein kinase C of annexin 2 in chromaffin cells stimulated by nicotine. J. Neurochem. 68:1997;1720-1727
44. Kumer S.C., Vrana K.E. Intricate regulation of tyrosine hydroxylase activity and gene expression. J. Neurochem. 67:1996;443-462
45. 2+ and cAMP in nicotine-elicited elevation of tyrosine hydroxylase mRNA. Am. J. Physiol. 276:1999;C54-C65
46. 2+-dependent activation of tyrosine hydroxylase involves MEK1. NeuroReport. 12:2001;2679-2683
47. Greenberg M.E., et al. Stimulation of neuronal acetylcholine receptors induces rapid gene transcription. Science. 234:1986;80-83
48. Salminen O., et al. The effects of acute nicotine on the metabolism of dopamine and the expression of Fos protein in striatal and limbic brain areas of rats during chronic nicotine infusion and its withdrawal. J. Neurosci. 19:1999;8145-8151
49. Dunckley T., Lukas R.J. Nicotine modulates the expression of a diverse set of genes in the neuronal SH-SY5Y cell line. J. Biol. Chem. 278:2003;15633-15640
50. Levin E.D., Simon B.B. Nicotinic acetylcholine involvement in cognitive function in animals. Psychopharmacology (Berl.). 138:1998;217-230
51. Sweatt J.D. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J. Neurochem. 76:2001;1-10
52. Nestler E.J. Common molecular and cellular substrates of addiction and memory. Neurobiol. Learn. Mem. 78:2002;637-647
53. Nakayama H., et al. Nicotine-induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12h cells. J. Neurochem. 79:2001;489-498
54. Chang K.T., Berg D.K. Voltage-gated channels block nicotinic regulation of creb phosphorylation and gene expression in neurons. Neuron. 32:2001;855-865
55. Dajas-Bailador F.A., et al. Nicotine activates the extracellular signal-regulated kinase 1/2 via the α7 nicotinic acetylcholine receptor and protein kinase A, in SH-SY5Y cells and hippocampal neurones. J. Neurochem. 80:2002;520-530
56. Hu M., et al. Nicotinic regulation of CREB activation in hippocampal neurons by glutamatergic and nonglutamatergic pathways. Mol. Cell. Neurosci. 21:2002;616-625
57. Ji D., et al. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron. 31:2001;131-141
58. Wang H.Y., et al. β-Amyloid(1-42) binds to α7 nicotinic acetylcholine receptor with high affinity. Implications for alzheimer's disease pathology. J. Biol. Chem. 275:2000;5626-5632
59. Liu Q., et al. β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons. Proc. Natl. Acad. Sci. U. S. A. 98:2001;4734-4739
60. Tozaki H., et al. The inhibitory and facilitatory actions of amyloid-β peptides on nicotinic ACh receptors and AMPA receptors. Biochem. Biophys. Res. Commun. 294:2002;42-45
61. Grassi F., et al. Amyloid β(1-42) peptide alters the gating of human and mouse alpha-bungarotoxin-sensitive nicotinic receptors. J. Physiol. 547:2003;147-157
62. Dineley K.T., et al. beta -Amyloid peptide activates α7 nicotinic acetylcholine receptors expressed in Xenopus oocytes. J. Biol. Chem. 277:2002;25056-25061
63. Fu W., Jhamandas J.H. β-amyloid peptide activates non-α7 nicotinic acetylcholine receptors in rat basal forebrain neurons. J. Neurophysiol. 90:2003;3130-3136
64. Dougherty J.J., et al. β-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex. J. Neurosci. 23:2003;6740-6747
65. Dineley K.T., et al. β-amyloid activates the mitogen-activated protein kinase cascade via hippocampal α7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J. Neurosci. 21:2001;4125-4133
66. Dineley K.T., et al. Accelerated plaque accumulation, associative learning deficits, and up-regulation of α7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins. J. Biol. Chem. 277:2002;22768-22780
67. Picciotto M.R. Nicotine as a modulator of behavior: beyond the inverted U. Trends Pharmacol. Sci. 24:2003;493-499
68. Wang H.Y., et al. α7 nicotinic acetylcholine receptors mediate β-amyloid peptide-induced tau protein phosphorylation. J. Biol. Chem. 278:2003;31547-31553
69. Dani J.A., et al. Synaptic plasticity and nicotine addiction. Neuron. 31:2001;349-352
70. Di Chiara G., Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl. Acad. Sci. U. S. A. 85:1988;5274-5278
71. Pidoplichko V.I., et al. Nicotine activates and desensitizes midbrain dopamine neurons. Nature. 390:1997;401-404
72. Laviolette S.R., van der Kooy D. The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour. Nat. Rev. Neurosci. 5:2004;55-65
73. Schilstrom B., et al. N-methyl-D-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens. Neuroscience. 82:1998;781-789
74. * nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area. Synapse. 38:2000;375-383
75. Mansvelder H.D., McGehee D.S. Long-term potentiation of excitatory inputs to brain reward areas by nicotine. Neuron. 27:2000;349-357
76. Pandey S.C., et al. Effects of protracted nicotine exposure and withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat brain. J. Neurochem. 77:2001;943-952
77. Brunzell D.H., et al. In vivo nicotine treatment regulates mesocorticolimbic CREB and ERK signaling in C57Bl/6J mice. J. Neurochem. 84:2003;1431-1441
78. Barrot M., et al. CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc. Natl. Acad. Sci. U. S. A. 99:2002;11435-11440
79. Pich E.M., et al. Common neural substrates for the addictive properties of nicotine and cocaine. Science. 275:1997;83-86
80. O'Neill M.J., et al. The role of neuronal nicotinic acetylcholine receptors in acute and chronic neurodegeneration. Curr. Drug Target CNS. Neurol. Disord. 1:2002;399-411
81. Donnelly-Roberts D.L., et al. In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418. Brain Res. 719:1996;36-44
82. 2+ dependent mechanism. Neuropharmacology. 39:2000;2799-2807
83. Ferchmin P.A., et al. Nicotinic receptors differentially regulate N-methyl-D-aspartate damage in acute hippocampal slices. J. Pharmacol. Exp. Ther. 305:2003;1071-1078
84. Prendergast M.A., et al. Chronic nicotine exposure reduces N-methyl-D-aspartate receptor-mediated damage in the hippocampus without altering calcium accumulation or extrusion: evidence of calbindin-D28K overexpression. Neuroscience. 102:2001;75-85
85. Stevens T.R., et al. Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation. J. Neurosci. 23:2003;10093-10099
86. Belluardo N., et al. Central nicotinic receptors, neurotrophic factors and neuroprotection. Behav. Brain Res. 113:2000;21-34
87. Kihara T., et al. α7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block Aβ-amyloid-induced neurotoxicity. J. Biol. Chem. 276:2001;13541-13546
88. Shaw S., et al. Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Aβ-(1-42) amyloid. J. Biol. Chem. 277:2002;44920-44924
89. Garrido R., et al. Nicotine protects against arachidonic-acid-induced caspase activation, cytochrome c release and apoptosis of cultured spinal cord neurons. J. Neurochem. 76:2001;1395-1403
90. Hejmadi M.V., et al. Neuroprotection by nicotine against hypoxia-induced apoptosis in cortical cultures involves activation of multiple nicotinic acetylcholine receptor subtypes. Mol. Cell. Neurosci. 24:2003;779-786
91. Wright S.C., et al. Nicotine inhibition of apoptosis suggests a role in tumor promotion. FASEB J. 7:1993;1045-1051
92. Heusch W.L., Maneckjee R. Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells. Carcinogenesis. 19:1998;551-556
93. Heeschen C., et al. Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis. Nat. Med. 7:2001;833-839
94. Jeanclos E.M., et al. The chaperone protein 14-3-3η interacts with the nicotinic acetylcholine receptor α4 subunit: Evidence for a dynamic role in subunit stabilization. J. Biol. Chem. 276:2001;28281-28290
95. Conroy W.G., et al. PDZ-containing proteins provide a functional postsynaptic scaffold for nicotinic receptors in neurons. Neuron. 38:2003;759-771
96. Parker M.J., et al. PSD93 regulates synaptic stability at neuronal cholinergic synapses. J. Neurosci. 24:2004;378-388