Effect of subtype selective nicotinic compounds on attention as assessed by the five-choice serial reaction time task

Behavioural Brain Research

Volumn 117, Issue 1-2, 2000, Pages 197-208

  Grottick, A J ^a   Higgins, G A ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

AR R 17779; Attention; Di hydro erythroidine (DH E); Five choice serial reaction time task (5 CSRTT); Methyllycaconitine (MLA); Nicotine; Rat; SIB 1765F; 4 2; 7

Indexed keywords

3 ETHYNYL 5 (1 METHYL 2 PYRROLIDINYL)PYRIDINE; 3 ETHYNYL 5 (1 METHYL 2 PYRROLIDINYL)PYRIDINE FUMARATE; DIHYDRO BETA ERYTHROIDINE; DIZOCILPINE; HEXAMETHONIUM; MECAMYLAMINE; METHYLLYCACONITINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; SPIRO[1 AZABICYCLO[2.2.2]OCTANE 3,2' THIAZOLIDINE] 2' ONE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; ATTENTION; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; FEEDING BEHAVIOR; LATENT PERIOD; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; TASK PERFORMANCE;

EID: 0034694951     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(00)00305-3     Document Type: Article

References (74)

1. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity
2. The effect of repeated nicotine administration on the performance of drug-nave rats in a five-choice serial reaction time task
3. Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: Antagonist studies
4. 2 receptor agonists and serotonergic anorectic drugs affect rats' performance differently in a five-choice serial reaction time task
5. Effects of lesions to ascending noradrenergic neurons on performance of a 5-choice serial reaction time task in rats: Implications for theories of dorsal bundle noradrenergic function based on selective attention and arousal
6. Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h alpha 2 beta 2, h alpha 2 beta 4, h alpha 3 beta 2, h alpha 3 beta 4, h alpha 4 beta 2, h alpha 4 beta 4 and h alpha 7 expressed in Xenopus oocytes
7. The effects of nicotine on locomotor activity in non-tolerant and tolerant rats
8. Characterization of the locomotor stimulant action of nicotine in tolerant rats
9. Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons
10. Central sympathomimetic activity of (+)-5-methyl-10,11-dihydro-5H-dibenzo [a,d] cyclohepten-5,10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic and apparent anxiolytic properties
11. Amphetamine impairs the discriminative performance of rats with dorsal noradrenergic bundle lesions on a 5-choice serial reaction time task: New evidence for central dopaminergic-noradrenergic interactions
12. Effects of 6-hydroxydopmaine lesions of the nucleus accumbens septi on performance of a 5-choice serial reaction time task in rats: Implications for theories of selective attention and arousal
13. Nicotine and attention in adult attention deficit hyperactivity disorder (ADHD)
14. Characterisation of the binding of [3H]methyllycaconitine: A new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors
15. Cholinergic activity in the rat hippocampus, cortex and striatum correlates with locomotor activity: An in vivo microdialysis study
16. Conditioned tolerance to the heart rate effects of smoking
17. Central cholinergic systems and cognition
18. Regulations restricting the sale and distribution of cigarettes and smokeless tobacco products to protect children and adolescents: Proposed rule
19. AR-R 17779: The first high affinity, subtype-selective full agonist at the rodent α7 nicotinic acetylcholine receptor
20. 7 agonist AR-R 17779 cross-sensitises to the psychostimulant effects of nicotine
21. 7 receptors are not involved in the hyperlocomotor and rewarding effects of nicotine
22. Comparison of nicotine and the alpha 7-selective agonist AR-R 17779 on nAchR α7 expressed in Xenopus oocytes
23. Central 5-HT depletion enhances impulsive responding without affecting the accuracy of attentional performance: Interactions with dopaminergic mechanisms
24. Doubly dissociable effects of median- and dorsal-raphe lesions on the performance of the five-choice serial reaction time test of attention in rats
25. Determinants of competitive antagonist sensitivity on neuronal nicotinic receptor beta subunits
26. What aspects of human performance are truly enhanced by nicotine?
27. Visuospatial attentional functioning in mice: Interactions between cholinergic manipulations and genotype
28. Increases in hippocampal and frontal cortical acetylcholine release associated with presentation of sensory stimuli
29. Enhanced acetylcholine release in hippocampus and cortex during the anticipation and consumption of a palatable meal
30. Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in disease
31. Age-associated impairments in a test of attention: Evidence for involvement of cholinergic systems
32. AR-R 17779, a selective α7 nicotinic agonist, has anxiolytic and sensory gating-enhancing properties and reduced nicotine-like side effects
33. Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes
34. Pathological mutations of nicotinic receptors and nicotine-based therapies for brain disorders
35. Nicotinic acetylcholine involvement in cognitive function in animals
36. Nicotine-haloperidol interactions and cognitive performance in schizophrenics
37. Transdermal nicotine effects on attention
38. AR-R 17779, an α7 nicotinic agonist, improves learning and memory in rats
39. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits
40. Selective effects of nicotine on attentional processes
41. Nicotine receptors in the central nervous system
42. Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function
43. Effects of a novel cholinergic ion channel agonist SIB-1765F on locomotor activity in rats
44. Nicotine enhances sustained attention in the rat under specific task conditions
45. The role of nicotinic and muscarinic acetylcholine receptors in attention
46. Attentional functions of the forebrain cholinergic systems: Effects of intraventricular hemicholinium, physostigmine, basal forebrain lesions and intracortical grafts on a multiple-choice serial reaction time task
47. AMPA-induced excitotoxic lesions of the basal forebrain: A significant role for the cortical cholinergic system in attentional function
48. 3 receptor antagonist, ondansetron
49. The cerebral cortex of the rat and visual attentional function: Dissociable effects of mediofrontal, cingulate, anterior dorsolateral, and parietal cortex lesions on a five-choice serial reaction time task
50. Nicotinic system involvement in Alzheimer's and Parkinsons's diseases
51. Mecamylamine is a selective non-competitive antagonist of N-methyl-D-aspartate and aspartate-induced currents in horizontal cells dissociated from the catfish retina
52. Evidence for an involvement of D1 and D2 dopamine receptors in mediating nicotine-induced hyperactivity in rats
53. 2 receptor blockade on MK-801-induced hyperlocomotion in rats
54. Neuronal nicotinic receptors in the human brain
55. A reappraisal of the nucleus basalis of Meynert
56. Comparative effects of ibotenic acid- and quisqualic acid-induced lesions of the substantia innominata on attentional function in the rat: Further implications for the role of the cholinergic neurons of the nucleus basalis in cognitive processes
57. Neural systems underlying arousal and attention
58. Nicotinic receptors in the development and modulation of CNS synapses
59. Effortful processing is a requirement for nicotine-induced improvements in memory
60. Blockade of muscarinic, rather than nicotinic receptors impairs attention but does not interact with serotonin depletion
61. Pharmacological characterisation of SIB-1765F: A novel cholinergic ion channel agonist
62. The effects of nicotine on attention, information processing, and short-term memory in patients with dementia of the Alzheimer type
63. Nicotine for the treatment of Tourette's syndrome
64. UB-165: A novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes
65. Noradrenaline and attention lapses
66. Inter-species consistency in the behavioural pharmacology of nicotine dependence
67. Selective antagonism of behavioural effects of nicotine by dihydro-β-erythroidine in rats
68. Nicotine in an animal model of attention
69. Cholinergic control of cognitive resources
70. Evaluation of the information processing and mood effects of a transdermal nicotine patch
71. Reward and somatic changes during precipitated nicotine withdrawal in rats: Centrally and peripherally mediated effects
72. Four-week nicotine skin patch treatment effects on cognitive performance in Alzheimer's disease
73. Neuronal responses related to reinforcement in the primate basal forebrain
74. Nicotine patches in Alzheimer's disease: Pilot study on learning, memory, and safety