Diet and cancer prevention studies in p53-deficient mice

Journal of Nutrition

Volumn 131, Issue 11 SUPPL., 2001, Pages

  Hursting, S D ^a   Perkins, S N ^a   Phang, J M ^a   Barrett, J C ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Calorie restriction; Chemoprevention; Insulin like growth factor 1; Leptin; Nutrition; Transgenic animals

Indexed keywords

CARBOHYDRATE; CYCLOOXYGENASE 2; FENRETINIDE; LEPTIN; PROTEIN P53; SOMATOMEDIN C;

ANIMAL MODEL; APOPTOSIS; BLADDER CARCINOGENESIS; CALORIC INTAKE; CALORIC RESTRICTION; CANCER PREVENTION; CARCINOGENESIS; CELL CYCLE; CONFERENCE PAPER; DIET; ENZYME INHIBITION; EPITHELIUM TUMOR; FOOD DEPRIVATION; GENETIC SUSCEPTIBILITY; KNOCKOUT MOUSE; LYMPHOMA; MOUSE; NONHUMAN; PROTEIN DETERMINATION; SARCOMA; THYMOCYTE; TUMOR SUPPRESSOR GENE;

ANIMALIA; MOUSE MAMMARY TUMOR VIRUS; MUS MUSCULUS;

EID: 0035160730     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/131.11.3092s     Document Type: Conference Paper

References (26)

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2. p53 mutations in human cancers
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4. Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
5. Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice
6. Calorie restriction induces a p53-independent delay of spontaneous carcinogenesis in p53-deficient and wild-type mice
7. Chemoprevention of spontaneous tumorigenesis in p53-knockout mice
8. Chemoprevention of spontaneous tumorigenesis in nullizygous p53-deficient mice by dehydroepiandrosterone and its analog, 16-α-fluoro-5-androsten-17-one
9. The anti-carcinogenic effects of dietary restriction: Mechanisms and future directions
10. Mechanism of cancer preventive action of DHEA. Role of glucose 6-phosphate dehydrogenase
11. Effects of dehydroepiandrosterone and calorie restriction on the Bcl-2/Bax-mediated apoptotic pathway in p53-deficient mice
12. The effects of calorie restriction on thymocyte growth, death and maturation
13. Dietary restriction reduces insulin-like growth factor-1 levels which modulates apoptosis, cell proliferation, and tumor progression in p53 deficient mice
14. Leptin regulates proinflammatory immune responses
15. Biological action of leptin as an angiogenic factor
16. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
17. p53-independent inhibition of nitric oxide generation by cancer preventive interventions in ex vivo mouse peritoneal macrophages
18. Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mice
19. Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice
20. Chemoprevention of azoxymethane-induced aberrant crypt foci and colon tumors in p53-deficient mice by sulindac
21. p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis
22. The growth hormone: Insulin-like growth factor 1 axis is a mediator of diet restriction-induced inhibition of mononuclear cell leukemia in Fischer rats
23. Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis
24. Effects of dietary restriction on spontaneous mammary tumorigenesis in p53-deficient Wnt-1 transgenic mice
25. Chemoprevention of spontaneous mammary tumorigenesis in p53-deficient Wnt-1 transgenic mice