Road to clinical efficacy: Challenges and novel strategies for antimicrobial peptide development

Future Microbiology

Volumn 6, Issue 6, 2011, Pages 635-651

  Eckert, Randal ^a  

^a C3 Jian Inc   (United States)

Author keywords

anti infective; antibiotic development; antibiotic resistance; antimicrobial peptide; lantibiotic; nanoparticle; narrow spectrum; peptide formulation; peptide stability; peptidomimetics; specifically targeted antimicrobial peptide; toxicit

Indexed keywords

ALPHA DEFENSIN; BL 2060; C16G2; CZEN 002; DAPTOMYCIN; DPK 060; GRAMICIDIN; HELIOMYCIN; ISEGANAN; LTX 109; NISIN; NVB302; NVB333; NVD333; OLIGOPEPTIDE; OMIGANAN; PAC 113; PEXIGANAN ACETATE; PLECTASIN; PMX 30036; PMX 30063; POL7001; POL7080; POLYMYXIN; UNCLASSIFIED DRUG; XOMA 629;

ANTIMICROBIAL ACTIVITY; CELL DEATH; CYTOTOXICITY; DRUG RESISTANCE; ENZYME ACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE DAMAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; RIBOSOME;

ANTIMICROBIAL CATIONIC PEPTIDES; CHEMISTRY, PHARMACEUTICAL; CLINICAL TRIALS AS TOPIC; COMMUNICABLE DISEASES; DRUG APPROVAL; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; HUMANS;

EID: 79959790048     PISSN: 17460913     EISSN: 17460921     Source Type: Journal    
DOI: 10.2217/fmb.11.27     Document Type: Review

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