-
1
-
-
0030963768
-
Role of cytokines in sepsis
-
Hack, C.E.; Aarden, L.A.; Thijs, L.G. Role of cytokines in sepsis.Adv. Immunol., 1997, 66, 101-195.
-
(1997)
Adv. Immunol
, vol.66
, pp. 101-195
-
-
Hack, C.E.1
Aarden, L.A.2
Thijs, L.G.3
-
2
-
-
33750047495
-
Management of sepsis
-
Russell, J.A. Management of sepsis. N. Engl. J. Med., 2006,355(16), 1699-1713.
-
(2006)
N. Engl. J. Med
, vol.355
, Issue.16
, pp. 1699-1713
-
-
Russell, J.A.1
-
3
-
-
14544299688
-
Therapeutic intervention and targets for sepsis
-
Rice, T.W.; Bernard, G.R. Therapeutic intervention and targets for sepsis. Annu. Rev. Med., 2005, 56, 225-248.
-
(2005)
Annu. Rev. Med
, vol.56
, pp. 225-248
-
-
Rice, T.W.1
Bernard, G.R.2
-
4
-
-
0029043636
-
A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group
-
Bone, R.C.; Balk, R.A.; Fein, A.M.; Perl, T.M.; Wenzel, R.P.; Reines, H.D.; Quenzer, R.W.; Iberti, T.J.; Macintyre, N.; Schein, R.M. A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group. Crit. Care Med., 1995, 23(6), 994-1006.
-
(1995)
Crit. Care Med
, vol.23
, Issue.6
, pp. 994-1006
-
-
Bone, R.C.1
Balk, R.A.2
Fein, A.M.3
Perl, T.M.4
Wenzel, R.P.5
Reines, H.D.6
Quenzer, R.W.7
Iberti, T.J.8
Macintyre, N.9
Schein, R.M.10
-
5
-
-
34247403460
-
Sepsis since the discovery of Toll-like receptors: Disease concepts and therapeutic opportunities
-
Leaver, S.K.; Finney, S.J.; Burke-Gaffney, A.; Evans, T.W. Sepsis since the discovery of Toll-like receptors: Disease concepts and therapeutic opportunities. Crit. Care Med., 2007, 35(5), 1404-1410.
-
(2007)
Crit. Care Med
, vol.35
, Issue.5
, pp. 1404-1410
-
-
Leaver, S.K.1
Finney, S.J.2
Burke-Gaffney, A.3
Evans, T.W.4
-
6
-
-
2442565752
-
-
Reinhart, K.; Gluck, T.; Ligtenberg, J.; Tschaikowsky, K.; Bruin- ing, A.; Bakker, J.; Opal, S.; Moldawer, L.L.; Axtelle, T.; Turner, T.; Souza, S.; Pribble, J. CD14 receptor occupancy in severe sepsis: results of a phase I clinical trial with a recombinant chimeric CD14 monoclonal antibody (IC14). Crit. Care Med., 2004, 32(5), 11001108.
-
Reinhart, K.; Gluck, T.; Ligtenberg, J.; Tschaikowsky, K.; Bruin- ing, A.; Bakker, J.; Opal, S.; Moldawer, L.L.; Axtelle, T.; Turner, T.; Souza, S.; Pribble, J. CD14 receptor occupancy in severe sepsis: results of a phase I clinical trial with a recombinant chimeric CD14 monoclonal antibody (IC14). Crit. Care Med., 2004, 32(5), 11001108.
-
-
-
-
7
-
-
0026016470
-
Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group
-
Ziegler, E.J.; Fisher, C.J., Jr.; Sprung, C.L.; Straube, R.C.; Sadoff, J.C.; Foulke, G.E.; Wortel, C.H.; Fink, M.P.; Dellinger, R.P.; Teng,N.N.; et. al. Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group. N. Engl. J. Med., 1991, 324(7), 429-436.
-
(1991)
N. Engl. J. Med
, vol.324
, Issue.7
, pp. 429-436
-
-
Ziegler, E.J.1
Fisher Jr., C.J.2
Sprung, C.L.3
Straube, R.C.4
Sadoff, J.C.5
Foulke, G.E.6
Wortel, C.H.7
Fink, M.P.8
Dellinger, R.P.9
Teng, N.N.10
et., al.11
-
8
-
-
0017804093
-
Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes
-
Weiss, J.; Elsbach, P.; Olsson, I.; Odeberg, H. Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes. J. Biol. Chem., 1978, 253(8), 2664-2672.
-
(1978)
J. Biol. Chem
, vol.253
, Issue.8
, pp. 2664-2672
-
-
Weiss, J.1
Elsbach, P.2
Olsson, I.3
Odeberg, H.4
-
9
-
-
0026497337
-
High- affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharide
-
Gazzano-Santoro, H.; Parent, J.B.; Grinna, L.; Horwitz, A.; Parsons, T.; Theofan, G.; Elsbach, P.; Weiss, J.; Conlon, P.J. High- affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharide. Infect. Immun., 1992, 60(11), 4754-4761.
-
(1992)
Infect. Immun
, vol.60
, Issue.11
, pp. 4754-4761
-
-
Gazzano-Santoro, H.1
Parent, J.B.2
Grinna, L.3
Horwitz, A.4
Parsons, T.5
Theofan, G.6
Elsbach, P.7
Weiss, J.8
Conlon, P.J.9
-
10
-
-
0028085132
-
Bacterial endotoxin: Molecular relationships of structure to activity and function
-
Rietschel, E.T.; Kirikae, T.; Schade, F.U.; Mamat, U.; Schmidt, G.; Loppnow, H.; Ulmer, A.J.; Zahringer, U.; Seydel, U.; Di Padova, F.; et. al. Bacterial endotoxin: molecular relationships of structure to activity and function. Faseb. J., 1994, 8(2), 217-225.
-
(1994)
Faseb. J
, vol.8
, Issue.2
, pp. 217-225
-
-
Rietschel, E.T.1
Kirikae, T.2
Schade, F.U.3
Mamat, U.4
Schmidt, G.5
Loppnow, H.6
Ulmer, A.J.7
Zahringer, U.8
Seydel, U.9
Di Padova, F.10
et., al.11
-
11
-
-
2342421291
-
rBPI(10-193) is secreted by CHO cells and retains the activity of rBPI21
-
Horwitz, A.H.; Ammons, W.S.; Bauer, R.J.; Dedrick, R.; Nadell, R.; Williams, R.E.; Liu, P.S. rBPI(10-193) is secreted by CHO cells and retains the activity of rBPI21. J. Endotoxin Res., 2004, 70(2), 97-106.
-
(2004)
J. Endotoxin Res
, vol.70
, Issue.2
, pp. 97-106
-
-
Horwitz, A.H.1
Ammons, W.S.2
Bauer, R.J.3
Dedrick, R.4
Nadell, R.5
Williams, R.E.6
Liu, P.S.7
-
12
-
-
0025883775
-
Endotoxin neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils
-
Ooi, C.E.; Weiss, J.; Doerfler, M.E.; Elsbach, P. Endotoxin neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils. J. Exp. Med., 1991, 174(3), 649-655.
-
(1991)
J. Exp. Med
, vol.174
, Issue.3
, pp. 649-655
-
-
Ooi, C.E.1
Weiss, J.2
Doerfler, M.E.3
Elsbach, P.4
-
13
-
-
0023525873
-
A 25- kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein
-
Ooi, C.E.; Weiss, J.; Elsbach, P.; Frangione, B.; Mannion, B. A 25- kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein. J. Biol. Chem., 1987, 262(31), 14891-14894.
-
(1987)
J. Biol. Chem
, vol.262
, Issue.31
, pp. 14891-14894
-
-
Ooi, C.E.1
Weiss, J.2
Elsbach, P.3
Frangione, B.4
Mannion, B.5
-
14
-
-
0028542299
-
Protective effects of a recombinant N-terminal fragment of bactericidal/ permeability increasing protein on endotoxic shock in conscious rabbits
-
Lin, Y.; Ammons, W.S.; Leach, W.J.; Kung, A.H. Protective effects of a recombinant N-terminal fragment of bactericidal/ permeability increasing protein on endotoxic shock in conscious rabbits. Shock, 1994, 2(5), 324-331.
-
(1994)
Shock
, vol.2
, Issue.5
, pp. 324-331
-
-
Lin, Y.1
Ammons, W.S.2
Leach, W.J.3
Kung, A.H.4
-
15
-
-
0029385205
-
The recombinant 23-kDa N-terminal fragment of bactericidal/permeability-increasing protein (rBPI23) decreases Es- cherichia coli-induced mortality and organ injury during immuno- suppression-related neutropenia
-
Lechner, A.J.; Lamprech, K.E.; Johanns, C.A.; Matuschak, G.M. The recombinant 23-kDa N-terminal fragment of bactericidal/permeability-increasing protein (rBPI23) decreases Es- cherichia coli-induced mortality and organ injury during immuno- suppression-related neutropenia. Shock, 1995, 4(4), 298-306.
-
(1995)
Shock
, vol.4
, Issue.4
, pp. 298-306
-
-
Lechner, A.J.1
Lamprech, K.E.2
Johanns, C.A.3
Matuschak, G.M.4
-
16
-
-
0028798378
-
Protective effects of a recombinant amino-terminal fragment of human bactericidal/ permeability-increasing protein in an animal model of gram-negative sepsis
-
Evans, T.J.; Carpenter, A.; Moyes, D.; Martin, R.; Cohen, J. Protective effects of a recombinant amino-terminal fragment of human bactericidal/ permeability-increasing protein in an animal model of gram-negative sepsis. J. Infect. Dis., 1995, 171(1), 153-160.
-
(1995)
J. Infect. Dis
, vol.171
, Issue.1
, pp. 153-160
-
-
Evans, T.J.1
Carpenter, A.2
Moyes, D.3
Martin, R.4
Cohen, J.5
-
17
-
-
0032941856
-
Bactericidal/permeability-increasing protein (rBPI21) in patients with hemorrhage due to trauma: Results of a multicenter phase II clinical trial. rBPI21 Acute Hemorrhagic Trauma Study Group
-
discussion 676-667
-
Demetriades, D.; Smith, J.S.; Jacobson, L.E.; Moncure, M.; Minei, J.; Nelson, B.J.; Scannon, P.J. Bactericidal/permeability-increasing protein (rBPI21) in patients with hemorrhage due to trauma: results of a multicenter phase II clinical trial. rBPI21 Acute Hemorrhagic Trauma Study Group. J. Trauma., 1999, 46(4), 667-676; discussion 676-667.
-
(1999)
J. Trauma
, vol.46
, Issue.4
, pp. 667-676
-
-
Demetriades, D.1
Smith, J.S.2
Jacobson, L.E.3
Moncure, M.4
Minei, J.5
Nelson, B.J.6
Scannon, P.J.7
-
18
-
-
0034675328
-
Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningo- coccal sepsis: A randomised trial. rBPI21 Meningococcal Sepsis Study Group
-
Levin, M.; Quint, P.A.; Goldstein, B.; Barton, P.; Bradley, J.S.;Shemie, S.D.; Yeh, T.; Kim, S.S.; Cafaro, D.P.; Scannon, P.J.; Gi roir, B.P. Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningo- coccal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group. Lancet, 2000, 356(9234), 961-967.
-
(2000)
Lancet
, vol.356
, Issue.9234
, pp. 961-967
-
-
Levin, M.1
Quint, P.A.2
Goldstein, B.3
Barton, P.4
Bradley, J.S.5
Shemie, S.D.6
Yeh, T.7
Kim, S.S.8
Cafaro, D.P.9
Scannon, P.J.10
Gi roir, B.P.11
-
19
-
-
0031583752
-
Preliminary evaluation of recombinant amino-terminal fragment of human bactericidal/permeability-increasing protein in children with severe meningococcal sepsis
-
Giroir, B.P.; Quint, P.A.; Barton, P.; Kirsch, E.A.; Kitchen, L.;Goldstein, B.; Nelson, B.J.; Wedel, N.J.; Carroll, S.F.; Scannon,.J. Preliminary evaluation of recombinant amino-terminal fragment of human bactericidal/permeability-increasing protein in children with severe meningococcal sepsis. Lancet, 1997, 350(9089), 1439-1443.
-
(1997)
Lancet
, vol.350
, Issue.9089
, pp. 1439-1443
-
-
Giroir, B.P.1
Quint, P.A.2
Barton, P.3
Kirsch, E.A.4
Kitchen, L.5
Goldstein, B.6
Nelson, B.J.7
Wedel, N.J.8
Carroll, S.F.9
Scannon, J.10
-
20
-
-
29144521244
-
Human antimicrobial peptides: Defens- ins, cathelicidins and histatins
-
De Smet, K.; Contreras, R. Human antimicrobial peptides: defens- ins, cathelicidins and histatins. Biotechnol. Lett., 2005, 27(18),1337-1347.
-
(2005)
Biotechnol. Lett
, vol.27
, Issue.18
, pp. 1337-1347
-
-
De Smet, K.1
Contreras, R.2
-
21
-
-
0037165196
-
Antimicrobial peptides of multicellular organisms
-
Zasloff, M. Antimicrobial peptides of multicellular organisms. Nature, 2002, 415(6870), 389-395.
-
(2002)
Nature
, vol.415
, Issue.6870
, pp. 389-395
-
-
Zasloff, M.1
-
22
-
-
0028933794
-
Peptide antibiotics and their role in innate immunity
-
Boman, H.G. Peptide antibiotics and their role in innate immunity. Annu. Rev. Immunol., 1995, 13,. 61-92.
-
(1995)
Annu. Rev. Immunol
, vol.13
, pp. 61-92
-
-
Boman, H.G.1
-
23
-
-
0028949278
-
Human CAP18: A novel antimicrobial lipopolysaccharide- binding protein
-
Larrick, J.W.; Hirata, M.; Balint, R.F.; Lee, J.; Zhong, J.; Wright,S.C. Human CAP18: a novel antimicrobial lipopolysaccharide- binding protein. Infect. Immun., 1995, 63(4), 1291-1297.
-
(1995)
Infect. Immun
, vol.63
, Issue.4
, pp. 1291-1297
-
-
Larrick, J.W.1
Hirata, M.2
Balint, R.F.3
Lee, J.4
Zhong, J.5
Wright, S.C.6
-
24
-
-
33644978944
-
Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of action
-
Rosenfeld, Y.; Papo, N.; Shai, Y. Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of action. J. Biol. Chem., 2006, 281(3), 1636-1643.
-
(2006)
J. Biol. Chem
, vol.281
, Issue.3
, pp. 1636-1643
-
-
Rosenfeld, Y.1
Papo, N.2
Shai, Y.3
-
25
-
-
0024590613
-
GCR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp containing peptides and a second site for bacterial lipopolysaccha ride
-
Wright, S.D.; Levin, S.M.; Jong, M.T.; Chad, Z.; Kabbash, L.GCR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp containing peptides and a second site for bacterial lipopolysaccha ride. J. Exp. Med., 1989, 169(1), 175-183.
-
(1989)
J. Exp. Med
, vol.169
, Issue.1
, pp. 175-183
-
-
Wright, S.D.1
Levin, S.M.2
Jong, M.T.3
Chad, Z.4
Kabbash, L.5
-
26
-
-
0023026362
-
Adhesion-promoting receptors on humanmacrophages recognize Escherichia coli by binding to lipopolysac- haride
-
Wright, S.D.; Jong, M.T. Adhesion-promoting receptors on humanmacrophages recognize Escherichia coli by binding to lipopolysac- haride. J. Exp. Med., 1986, 164(6), 1876-1888.
-
(1986)
J. Exp. Med
, vol.164
, Issue.6
, pp. 1876-1888
-
-
Wright, S.D.1
Jong, M.T.2
-
27
-
-
0028909814
-
CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide
-
Ingalls, R.R.; Golenbock, D.T. CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide. J. Exp. Med., 1995,181(4), 1473-1479.
-
(1995)
J. Exp. Med
, vol.181
, Issue.4
, pp. 1473-1479
-
-
Ingalls, R.R.1
Golenbock, D.T.2
-
28
-
-
0031278065
-
CD11/CD18 leukocyte integrins: New signaling receptors for bacterial endotoxin
-
Flaherty, S.F.; Golenbock, D.T.; Milham, F.H.; Ingalls, R.R.CD11/CD18 leukocyte integrins: new signaling receptors for bacterial endotoxin. J. Surg. Res., 1997, 73(1), 85-89.
-
(1997)
J. Surg. Res
, vol.73
, Issue.1
, pp. 85-89
-
-
Flaherty, S.F.1
Golenbock, D.T.2
Milham, F.H.3
Ingalls, R.R.4
-
29
-
-
35248867073
-
Characterization of two novel LPS-binding sites in leukocyte in- tegrin {beta}A domain
-
Wong, K.F.; Luk, J.M.; Cheng, R.H.; Klickstein, L.B.; Fan, S.T.Characterization of two novel LPS-binding sites in leukocyte in- tegrin {beta}A domain. FASEB J., 2007, 21(12), 3231-3239.
-
(2007)
FASEB J
, vol.21
, Issue.12
, pp. 3231-3239
-
-
Wong, K.F.1
Luk, J.M.2
Cheng, R.H.3
Klickstein, L.B.4
Fan, S.T.5
-
30
-
-
0035884820
-
Cathelicidin family of antibacterial pep- tides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells
-
Nagaoka, I.; Hirota, S.; Niyonsaba, F.; Hirata, M.; Adachi, Y.; Tamura, H.; Heumann, D. Cathelicidin family of antibacterial pep- tides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells. J. Immunol., 2001, 167(6), 3329-3338.
-
(2001)
J. Immunol
, vol.167
, Issue.6
, pp. 3329-3338
-
-
Nagaoka, I.1
Hirota, S.2
Niyonsaba, F.3
Hirata, M.4
Adachi, Y.5
Tamura, H.6
Heumann, D.7
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