Role of peptide hydrophobicity in the mechanism of action of α-helical antimicrobial peptides

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 4, 2007, Pages 1398-1406

  Chen, Yuxin ^a   Guarnieri, Michael T ^a   Vasil, Adriana I ^a   Vasil, Michael L ^a   Mant, Colin T ^a   Hodges, Robert S ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYPEPTIDE ANTIBIOTIC AGENT;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CIRCULAR DICHROISM; DRUG MECHANISM; HEMOLYSIS; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; BINDING SITES; DRUG DESIGN; HYDROPHOBICITY; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PSEUDOMONAS AERUGINOSA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34247153326     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00925-06     Document Type: Article

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