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Volumn 40, Issue 5, 1996, Pages 1067-1071

Synthetic combinatorial libraries: Novel discovery strategy for identification of antimicrobial agents

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; BETA LACTAM ANTIBIOTIC; CARBAPENEM DERIVATIVE; PENEM DERIVATIVE; PENICILLIN BINDING PROTEIN; PENICILLIN G DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; VANCOMYCIN;

EID: 0029867221     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.5.1067     Document Type: Short Survey
Times cited : (77)

References (45)
  • 2
    • 0027043261 scopus 로고
    • Design of model peptides having potent antimicrobial activities
    • Blondelle, S. E., and R. A. Houghten. 1992 Design of model peptides having potent antimicrobial activities. Biochemistry 31:12688-12694
    • (1992) Biochemistry , vol.31 , pp. 12688-12694
    • Blondelle, S.E.1    Houghten, R.A.2
  • 3
    • 0028890190 scopus 로고
    • Induced conformational states of amphipathic peptides in aqueous/lipid environments
    • Blondelle, S. E., J. M. Ostresh, R. A. Houghten, and E. Pérez-Payá. 1995. Induced conformational states of amphipathic peptides in aqueous/lipid environments. Biophys J. 68:351-359.
    • (1995) Biophys J. , vol.68 , pp. 351-359
    • Blondelle, S.E.1    Ostresh, J.M.2    Houghten, R.A.3    Pérez-Payá, E.4
  • 5
    • 0028950911 scopus 로고
    • The antimicrobial activity of hexapeptides derived from synthetic combinatorial libraries
    • Blondelle, S. E., E. Takahashi, K. T. Dinh, and R. A. Houghten. 1995. The antimicrobial activity of hexapeptides derived from synthetic combinatorial libraries. J. Appl. Bacteriol. 78:39-46.
    • (1995) J. Appl. Bacteriol. , vol.78 , pp. 39-46
    • Blondelle, S.E.1    Takahashi, E.2    Dinh, K.T.3    Houghten, R.A.4
  • 6
    • 0030049034 scopus 로고    scopus 로고
    • Rapid identification of compounds having enhanced antimicrobial activity using conformationally defined combinatorial libraries
    • Blondelle, S. E., E. Takahashi, R. A. Houghten, and E. Pérez-Payá. 1996. Rapid identification of compounds having enhanced antimicrobial activity using conformationally defined combinatorial libraries. Biochem. J. 313:141-147.
    • (1996) Biochem. J. , vol.313 , pp. 141-147
    • Blondelle, S.E.1    Takahashi, E.2    Houghten, R.A.3    Pérez-Payá, E.4
  • 7
    • 0028064952 scopus 로고
    • Identification of antimicrobial peptides using combinatorial libraries made up of unnatural amino acids
    • Blondelle, S. E., E. Takahashi, P. A. Weber, and R. A. Houghten. 1994. Identification of antimicrobial peptides using combinatorial libraries made up of unnatural amino acids. Antimicrob. Agents Chemother. 38:2280-2286.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 2280-2286
    • Blondelle, S.E.1    Takahashi, E.2    Weber, P.A.3    Houghten, R.A.4
  • 8
  • 9
    • 77956847918 scopus 로고
    • Recent developments in antibacterial resistance mechanisms
    • Brighty, K. E., W. Kohlbrenner, and P. R. McGuirk, 1993 Recent developments in antibacterial resistance mechanisms. Annu. Rep Med Chem. 28: 141-150.
    • (1993) Annu. Rep Med Chem. , vol.28 , pp. 141-150
    • Brighty, K.E.1    Kohlbrenner, W.2    McGuirk, P.R.3
  • 10
    • 0024604271 scopus 로고
    • Methicillin-resistance Staphylococcus aureus
    • Brumfitt, W., and J. Hamilton-Miller. 1989. Methicillin-resistance Staphylococcus aureus. N. Engl. J. Med 320:1188-1196.
    • (1989) N. Engl. J. Med , vol.320 , pp. 1188-1196
    • Brumfitt, W.1    Hamilton-Miller, J.2
  • 11
    • 0027068161 scopus 로고
    • A general and expedient method for the solid-phase synthesis of 1,4-benzodiazepine derivatives
    • Bunin, B. A., and J- A. Ellman. 1992. A general and expedient method for the solid-phase synthesis of 1,4-benzodiazepine derivatives J. Am. Chem. Soc. 114:10997-10998
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 10997-10998
    • Bunin, B.A.1    Ellman, J.-A.2
  • 12
    • 33748235487 scopus 로고
    • A novel procedure for the synthesis of libraries containing small organic molecules
    • Carell, T., E. A. Wintner, A. Bashir-Hashemi, and J. Rebek, Jr. 1994. A novel procedure for the synthesis of libraries containing small organic molecules. Angew. Chem. Int. Ed. Engl. 33:2059-2061.
    • (1994) Angew. Chem. Int. Ed. Engl. , vol.33 , pp. 2059-2061
    • Carell, T.1    Wintner, E.A.2    Bashir-Hashemi, A.3    Rebek Jr., J.4
  • 13
    • 3743084024 scopus 로고
    • "Analogous" organic synthesis of small-compound libraries: Validation of combinatorial chemistry in small molecule synthesis
    • Chen, C., L. A. Ahlberg-Randall, R. B. Miller, A. D. Jones, and M. J. Kurth. 1994. "Analogous" organic synthesis of small-compound libraries: validation of combinatorial chemistry in small molecule synthesis J. Am. Chem. Soc. 116:2661-2662
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 2661-2662
    • Chen, C.1    Ahlberg-Randall, L.A.2    Miller, R.B.3    Jones, A.D.4    Kurth, M.J.5
  • 16
    • 23444440823 scopus 로고
    • Inactivation of antibiotics and the dissemination of resistance genes
    • Davies, J. 1994. Inactivation of antibiotics and the dissemination of resistance genes. Science 264:375-382
    • (1994) Science , vol.264 , pp. 375-382
    • Davies, J.1
  • 19
    • 8744315950 scopus 로고
    • Extending the range of molecular diversity through amide alkylation of peptide libraries
    • H. L. S. Maia (ed.). ESCOM. Leiden, The Netherlands
    • Dorner, B., J. M. Ostresh, G. M. Husar, and R. A, Houghten. 1995. Extending the range of molecular diversity through amide alkylation of peptide libraries, p. 463-464. In H. L. S. Maia (ed.). Peptides 94: Proceedings of the 23rd European Peptide Symposium. ESCOM. Leiden, The Netherlands
    • (1995) Peptides 94: Proceedings of the 23rd European Peptide Symposium , pp. 463-464
    • Dorner, B.1    Ostresh, J.M.2    Husar, G.M.3    Houghten, R.A.4
  • 20
    • 0026108692 scopus 로고
    • Light-directed, spatially addressable parallel chemical synthesis
    • Fodor, S. P. A., J. L. Read, M. C. Pirrung, L. Stryer, A. T. Lu, and D. Solas. 1991. Light-directed, spatially addressable parallel chemical synthesis Science 251:767-773
    • (1991) Science , vol.251 , pp. 767-773
    • Fodor, S.P.A.1    Read, J.L.2    Pirrung, M.C.3    Stryer, L.4    Lu, A.T.5    Solas, D.6
  • 21
    • 0028243847 scopus 로고
    • Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries
    • Gallop, M. A., R. W. Barrett, W. J. Dower, S. P. A. Fodor, and E. M. Gordon. 1994. Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries. J. Med. Chem. 37:1233-1251.
    • (1994) J. Med. Chem. , vol.37 , pp. 1233-1251
    • Gallop, M.A.1    Barrett, R.W.2    Dower, W.J.3    Fodor, S.P.A.4    Gordon, E.M.5
  • 22
    • 0022646579 scopus 로고
    • A priori delineation of a peptide which mimics a discontinuous antigenic determinant
    • Geysen, H. M., S. J. Rodda, and T. J. Mason. 1986. A priori delineation of a peptide which mimics a discontinuous antigenic determinant. Mol Immunol 23:709-715.
    • (1986) Mol Immunol , vol.23 , pp. 709-715
    • Geysen, H.M.1    Rodda, S.J.2    Mason, T.J.3
  • 23
    • 0028318863 scopus 로고
    • Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions
    • Gordon, E. M., R. W. Barrett, W. J. Dower, S. P. A. Fodor, and M. A. Gallop. 1994. Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions. J. Med. Chem 37:1385-1401.
    • (1994) J. Med. Chem , vol.37 , pp. 1385-1401
    • Gordon, E.M.1    Barrett, R.W.2    Dower, W.J.3    Fodor, S.P.A.4    Gallop, M.A.5
  • 24
    • 0000478940 scopus 로고
    • General method for the rapid solid-phase synthesis of large numbers of peptides: Specificity of antigen-antibody interaction at the level of individual amino acids
    • Houghten, R. A. 1985. General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. Proc. Natl Acad. Sci. USA 82:5131-5135.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 5131-5135
    • Houghten, R.A.1
  • 25
    • 0026698930 scopus 로고
    • The use of synthetic peptide combinatorial libraries for the identification of bioactive peptides
    • Houghten, R. A., J. R. Appel, S. E. Blondelle, J. H. Cuervo, C. T. Dooley, and C. Pinilla. 1992. The use of synthetic peptide combinatorial libraries for the identification of bioactive peptides BioTechniques 13:412-421.
    • (1992) BioTechniques , vol.13 , pp. 412-421
    • Houghten, R.A.1    Appel, J.R.2    Blondelle, S.E.3    Cuervo, J.H.4    Dooley, C.T.5    Pinilla, C.6
  • 26
    • 0022728936 scopus 로고
    • Simplified procedure for carrying out simultaneous multiple hydrogen fluoride cleavages of protected peptide resins
    • Houghten, R. A., M. K. Bray, S. T. De Graw, and C. J. Kirby. 1986. Simplified procedure for carrying out simultaneous multiple hydrogen fluoride cleavages of protected peptide resins. Int J. Peptide Protein Res 27:673-678
    • (1986) Int J. Peptide Protein Res , vol.27 , pp. 673-678
    • Houghten, R.A.1    Bray, M.K.2    De Graw, S.T.3    Kirby, C.J.4
  • 27
    • 0013596553 scopus 로고
    • The systematic development of peptides having potent antimicrobial activity against E. coli through the use of synthetic peptide combinatorial libraries
    • R. H. Angeletti (ed.), Academic Press, Inc, Orlando. Fla
    • Houghten, R. A., K. T. Dinh, D. E. Burcin, and S. E. Blondelle. 1993. The systematic development of peptides having potent antimicrobial activity against E. coli through the use of synthetic peptide combinatorial libraries, p. 249-256. In R. H. Angeletti (ed.), Techniques in protein chemistry IV. Academic Press, Inc, Orlando. Fla
    • (1993) Techniques in Protein Chemistry IV , pp. 249-256
    • Houghten, R.A.1    Dinh, K.T.2    Burcin, D.E.3    Blondelle, S.E.4
  • 28
    • 0026419319 scopus 로고
    • Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery
    • Houghten, R. A., C. Pinilla, S. E. Blondelle, J. R. Appel, C. T. Dooley, and J. H. Cuervo. 1991 Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery. Nature (London) 354:84-86.
    • (1991) Nature (London) , vol.354 , pp. 84-86
    • Houghten, R.A.1    Pinilla, C.2    Blondelle, S.E.3    Appel, J.R.4    Dooley, C.T.5    Cuervo, J.H.6
  • 29
    • 15844373605 scopus 로고
    • Polymoxin, colistin and bacitracin
    • Jawetz, E. 1961. Polymoxin, colistin and bacitracin Pediatr. Clin. N. Am. 8:1057-1071
    • (1961) Pediatr. Clin. N. Am. , vol.8 , pp. 1057-1071
    • Jawetz, E.1
  • 31
    • 0023139623 scopus 로고
    • Antimicrobial resistance of Staphylococcus aureus: Genetic basis
    • Lyon, B. R., and R. Skurray. 1987. Antimicrobial resistance of Staphylococcus aureus: genetic basis. Microbiol. Rev. 51:88-134.
    • (1987) Microbiol. Rev. , vol.51 , pp. 88-134
    • Lyon, B.R.1    Skurray, R.2
  • 32
    • 20744456789 scopus 로고
    • Peptide synthesis. I the synthesis of a tetrapeptide
    • Merrifield, R. B. 1963. Peptide synthesis. I The synthesis of a tetrapeptide. J. Am Chem. Soc. 85:2149-2154.
    • (1963) J. Am Chem. Soc. , vol.85 , pp. 2149-2154
    • Merrifield, R.B.1
  • 35
    • 0026760182 scopus 로고
    • The crisis in antibiotic resistance
    • Neu, H. C. 1992. The crisis in antibiotic resistance. Science 257:1064-1078.
    • (1992) Science , vol.257 , pp. 1064-1078
    • Neu, H.C.1
  • 36
    • 0028173391 scopus 로고
    • "Libraries from libraries": Chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity
    • Ostresh, J. M., G. M. Husar, S. E. Blondelle, B. Dörner, P. A. Weber, and R. A. Houghten. 1994 "Libraries from libraries": chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity, Proc. Natl. Acad. Sci. USA 91:11138-11142.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11138-11142
    • Ostresh, J.M.1    Husar, G.M.2    Blondelle, S.E.3    Dörner, B.4    Weber, P.A.5    Houghten, R.A.6
  • 38
    • 0028100130 scopus 로고
    • Versatility of positional scanning synthetic combinatorial libraries, for the identification of individual compounds
    • Pinilla, C., J. R. Appel, S. E. Blondelle, C. T. Dooley, J. Eichler, J. M. Ostresh, and R. A. Houghten. 1994. Versatility of positional scanning synthetic combinatorial libraries, for the identification of individual compounds Drug Dev Res. 33:133-145
    • (1994) Drug Dev Res. , vol.33 , pp. 133-145
    • Pinilla, C.1    Appel, J.R.2    Blondelle, S.E.3    Dooley, C.T.4    Eichler, J.5    Ostresh, J.M.6    Houghten, R.A.7
  • 39
    • 0025029939 scopus 로고
    • Antibacterial polypeptides of Lactobacillus species
    • Rammelsberg, M., and F. Radler. 1990. Antibacterial polypeptides of Lactobacillus species. J. Appl Bacteriol. 69:177-184.
    • (1990) J. Appl Bacteriol. , vol.69 , pp. 177-184
    • Rammelsberg, M.1    Radler, F.2
  • 40
    • 0028339191 scopus 로고
    • Cell-lytic and antibacterial peptides that act by perturbing the barrier function of membranes facets of their conformational features, structure function correlations and membrane-perturbing abilities
    • Saberwal, G., and R. Nagaraj. 1994. Cell-lytic and antibacterial peptides that act by perturbing the barrier function of membranes facets of their conformational features, structure function correlations and membrane-perturbing abilities. Biochim. Biophys. Acta Rev. Biomembr. 1197:109-131.
    • (1994) Biochim. Biophys. Acta Rev. Biomembr. , vol.1197 , pp. 109-131
    • Saberwal, G.1    Nagaraj, R.2
  • 45
    • 0026511839 scopus 로고
    • Antiobiotic peptides as mediators of innate immunity
    • Zasloff, M. 1992. Antiobiotic peptides as mediators of innate immunity. Curr. Opin. Immunol. 4:3-7
    • (1992) Curr. Opin. Immunol. , vol.4 , pp. 3-7
    • Zasloff, M.1


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