Chewing gum of antimicrobial decapeptide (KSL) as a sustained antiplaque agent: Preformulation study

Journal of Controlled Release

Volumn 107, Issue 1, 2005, Pages 122-130

  Na, Dong Hee ^a   Faraj, Jabar ^b   Capan, Yilmaz ^c   Leung, Kai P ^d   DeLuca, Patrick P ^b  

^a Kyungsung University   (South Korea)

^b University of Kentucky   (United States)

^c HACETTEPE UNIVERSITY   (Turkey)

^d WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

Antimicrobial peptide; Antiplaque agent; Chewing gum; In vitro and in vivo release; Stability

Indexed keywords

BACTERIA; FOOD PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYAPATITE; MASTICATION; MICROBIOLOGY; PH EFFECTS; STABILITY;

ANTIMICROBIAL PEPTIDE; ANTIPLAQUE AGENT; CHEWING GUM; IN VITRO AND IN VIVO RELEASE;

AMINES;

ACETIC ACID; BUFFER; HYDROXYAPATITE; LYSYLLYSYLVALYLVALYLPHENYLALANYLLYSYLVALYLLYSYLPHENYLALANYLLYSINAMIDE; POLYPEPTIDE ANTIBIOTIC AGENT; SALIVA SUBSTITUTE; UNCLASSIFIED DRUG;

APPARATUS; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BINDING AFFINITY; CHEWING GUM; DENTAL CARIES; DISEASE COURSE; DRUG STABILITY; MATERIALS; MOUTH CAVITY; PREFORMULATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SUSTAINED RELEASE PREPARATION; TIME; TOOTH PLAQUE;

ANTI-BACTERIAL AGENTS; CHEWING GUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DELAYED-ACTION PREPARATIONS; DENTAL PLAQUE; DEPSIPEPTIDES; DRUG DELIVERY SYSTEMS; DRUG STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROXYAPATITES; SALIVA; TEMPERATURE; TIME FACTORS; WATER;

EID: 24344443320     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.05.027     Document Type: Article

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