De novo generation of cationic antimicrobial peptides: Influence of length and tryptophan substitution on antimicrobial activity

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 1, 2005, Pages 316-322

  Deslouches, Berthony ^a   Phadke, Shruti M ^b   Lazarevic, Vanja ^a   Cascio, Michael ^a   Islam, Kazi ^a   Montelaro, Ronald C ^a   Mietzner, Timothy A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CATION; LENTIVIRUS LYTIC PEPTIDE 1; PEPTIDE ANTIBIOTIC WLBU2; POLYPEPTIDE ANTIBIOTIC AGENT; SODIUM CHLORIDE; UNCLASSIFIED DRUG; VALINE; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANTIMICROBIAL ACTIVITY; ARTICLE; CATION EXCHANGE; CATION TRANSPORT; CHEMICAL COMPOSITION; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CORRELATION ANALYSIS; DIAGNOSTIC VALUE; DRUG DESIGN; DRUG SELECTIVITY; EVALUATION; HUMAN IMMUNODEFICIENCY VIRUS; HYDROPHOBICITY; INFECTION; LENTIVIRINAE; MEMBRANE BINDING; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; PSEUDOMONAS AERUGINOSA; SKIN FIBROBLAST; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANTIMICROBIAL CATIONIC PEPTIDES; CELLS, CULTURED; CIRCULAR DICHROISM; COCULTURE TECHNIQUES; DRUG DESIGN; FIBROBLASTS; HUMANS; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; SKIN; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN;

EID: 11244267508     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.1.316-322.2005     Document Type: Article

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