A clonogenic bone harrow progenitor specific for macrophages and dendritic cells

Science

Volumn 311, Issue 5757, 2006, Pages 83-87

  Fogg, Darin K ^a   Sibon, Claire ^a   Miled, Chaouki ^a   Jung, Steffen ^b   Aucouturier, Pierre ^c   Littman, Dan R ^d   Cumano, Ana ^e,f   Geissmann, Frederic ^a,g  

^a INSTITUT NECKER ENFANTS MALADES   (France)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c INSERM   (France)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e INSTITUT PASTEUR   (France)

^f INSTITUT PASTEUR   (France)

^g HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; IMMUNOLOGY; LIVING SYSTEMS STUDIES; MEDICAL PROBLEMS;

BONE HARROW PROGENITOR; INFLAMMATORY RESPONSES; MACROPHAGES;

BONE;

COLONY STIMULATING FACTOR; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; COLONY STIMULATING FACTOR 1; CYTOKINE RECEPTOR; RECOMBINANT COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STEM CELL FACTOR RECEPTOR; V28 RECEPTOR; VIRUS RECEPTOR;

CELLS AND CELL COMPONENTS;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL ISOLATION; CELL LINEAGE; CELL SPECIFICITY; CLONOGENESIS; CYTOKINE PRODUCTION; DENDRITIC CELL; IMMUNE RESPONSE; INFLAMMATION; MACROPHAGE; MOLECULAR BIOLOGY; MONONUCLEAR PHAGOCYTE SYSTEM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; STEM CELL; ANIMAL; C57BL MOUSE; CELL CLONE; CELL SEPARATION; CYTOLOGY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOLOGY; MYELOID PROGENITOR CELL; SPLEEN;

ANIMALIA;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL SEPARATION; CLONE CELLS; COLONY-STIMULATING FACTORS, RECOMBINANT; DENDRITIC CELLS; FLOW CYTOMETRY; GRANULOCYTE COLONY STIMULATING FACTOR, RECOMBINANT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MICE; MICE, INBRED C57BL; MYELOID PROGENITOR CELLS; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTORS, CYTOKINE; RECEPTORS, HIV; SPLEEN;

EID: 30344444770     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1117729     Document Type: Article

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30. The authors thank P. Leenen and B. Rocha for the kind gift of antibodies; J. Megret and C. Cordier for expert help with cell sorting; the members of the Geissmann lab for helpful discussions and critical analysis of the experiments and of the manuscript; and P. Kelly, N. Brousse, P. Berche, and J. L. Casanova for support. D.K.F. was supported by the INSERM (poste vert), C.S. was supported by the Fondation pour la Recherche Medicale (FRM) and the Fond d'Etude et de Recherche du Corps Médical des Hôpitaux de Paris, C.M. by the Fondation Schlumberger, and D.R.L. by NIH grant A133856. F.G. was supported by young investigator awards from INSERM (Avenir award), the City of Paris, the FRM, the Fondation de France, and the Fondation Schlumberger.