CD95-Ligand on Peripheral Myeloid Cells Activates Syk Kinase to Trigger Their Recruitment to the Inflammatory Site

Immunity

Volumn 32, Issue 2, 2010, Pages 240-252

  Letellier, Elisabeth ^a   Kumar, Sachin ^a   Sancho Martinez, Ignacio ^a   Krauth, Stefanie ^a   Funke Kaiser, Anne ^a   Laudenklos, Sabrina ^a   Konecki, Katrin ^a   Klussmann, Stefan ^a   Corsini, Nina S ^a   Kleber, Susanne ^a   Drost, Natalia ^a   Neumann, Andreas ^a   Lévi Strauss, Matthieu ^c   Brors, Benedikt ^a   Gretz, Norbert ^d   Edler, Lutz ^a   Fischer, Carmen ^b   Hill, Oliver ^b   Thiemann, Meinolf ^b   Biglari, Bahram ^e   Karray, Saoussen ^c   Martin Villalba, Ana ^a   more..

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b APOGENIX GMBH   (Germany)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e BG UNFALLKLINIK LUDWIGSHAFEN   (Germany)

Author keywords

CELLIMMUNO; MOLIMMUNO

Indexed keywords

FAS LIGAND; GELATINASE B; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE SYK; THIOGLYCOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; HUMAN; INFLAMMATION; MACROPHAGE MIGRATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OLIGODENDROGLIA; PERITONITIS; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; FAS LIGAND PROTEIN; HUMANS; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID CELLS; PERITONEUM; PERITONITIS; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SPINAL CORD; THIOGLYCOLATES;

EID: 76949101422     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2010.01.011     Document Type: Article

References (52)

1. Ackery A., Robins S., and Fehlings M.G. Inhibition of Fas-mediated apoptosis through administration of soluble Fas receptor improves functional outcome and reduces posttraumatic axonal degeneration after acute spinal cord injury. J. Neurotrauma 23 (2006) 604-616
2. Akuzawa S., Kazui T., Shi E., Yamashita K., Bashar A.H., and Terada H. Interleukin-1 receptor antagonist attenuates the severity of spinal cord ischemic injury in rabbits. J. Vasc. Surg. 48 (2008) 694-700
3. Ali K., Bilancio A., Thomas M., Pearce W., Gilfillan A.M., Tkaczyk C., Kuehn N., Gray A., Giddings J., Peskett E., et al. Essential role for the p110delta phosphoinositide 3-kinase in the allergic response. Nature 431 (2004) 1007-1011
4. Allison J., Georgiou H.M., Strasser A., and Vaux D.L. Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts. Proc. Natl. Acad. Sci. USA 94 (1997) 3943-3947
5. Altemeier W.A., Zhu X., Berrington W.R., Harlan J.M., and Liles W.C. Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspase-independent pathway. J. Leukoc. Biol. 82 (2007) 721-728
6. Atkinson E.A., Ostergaard H., Kane K., Pinkoski M.J., Caputo A., Olszowy M.W., and Bleackley R.C. A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT. J. Biol. Chem. 271 (1996) 5968-5971
7. Austin J.W., and Fehlings M.G. Molecular mechanisms of Fas-mediated cell death in oligodendrocytes. J. Neurotrauma 25 (2008) 411-426
8. Basso D.M., Fisher L.C., Anderson A.J., Jakeman L.B., McTigue D.M., and Popovich P.G. Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. J. Neurotrauma 23 (2006) 635-659
9. Baruzzi A., Caveggion E., and Berton G. Regulation of phagocyte migration and recruitment by Src-family kinases. Cell. Mol. Life Sci. 65 (2008) 2175-2190
10. Baud V., and Karin M. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol. 11 (2001) 372-377
11. Brown S.B., and Savill J. Phagocytosis triggers macrophage release of Fas ligand and induces apoptosis of bystander leukocytes. J. Immunol. 162 (1999) 480-485
12. Casha S., Yu W.R., and Fehlings M.G. FAS deficiency reduces apoptosis, spares axons and improves function after spinal cord injury. Exp. Neurol. 196 (2005) 390-400
13. Corsini N.S., Sancho-Martinez I., Laudenklos S., Glagow D., Kumar S., Letellier E., Koch P., Teodorczyk M., Kleber S., Klussmann S., et al. The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair. Cell Stem Cell 5 (2009) 178-190
14. Daigle I., Yousefi S., Colonna M., Green D.R., and Simon H.U. Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils. Nat. Med. 8 (2002) 61-67
15. Demjen D., Klussmann S., Kleber S., Zuliani C., Stieltjes B., Metzger C., Hirt U.A., Walczak H., Falk W., Essig M., et al. Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury. Nat. Med. 10 (2004) 389-395
16. Desbarats J., Birge R.B., Mimouni-Rongy M., Weinstein D.E., Palerme J.S., and Newell M.K. Fas engagement induces neurite growth through ERK activation and p35 upregulation. Nat. Cell Biol. 5 (2003) 118-125
17. Dhein J., Walczak H., Bäumler C., Debatin K.M., and Krammer P.H. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373 (1995) 438-441
18. Fecho K., and Cohen P.L. Fas ligand (gld)- and Fas (lpr)-deficient mice do not show alterations in the extravasation or apoptosis of inflammatory neutrophils. J. Leukoc. Biol. 64 (1998) 373-383
19. Frommhold D., Mannigel I., Schymeinsky J., Mocsai A., Poeschl J., Walzog B., and Sperandio M. Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo. BMC Immunol. 8 (2007) 31
20. Gonzalez R., Hickey M.J., Espinosa J.M., Nistor G., Lane T.E., and Keirstead H.S. Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice. Regen. Med. 2 (2007) 771-783
21. Gresham H.D., Ray C.J., and O'Sullivan F.X. Defective neutrophil function in the autoimmune mouse strain MRL/lpr. Potential role of transforming growth factor-beta. J. Immunol. 146 (1991) 3911-3921
22. Griffith T.S., Brunner T., Fletcher S.M., Green D.R., and Ferguson T.A. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270 (1995) 1189-1192
23. Griffith T.S., Yu X., Herndon J.M., Green D.R., and Ferguson T.A. CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance. Immunity 5 (1996) 7-16
24. Hahne M., Rimoldi D., Schröter M., Romero P., Schreier M., French L.E., Schneider P., Bornand T., Fontana A., Lienard D., et al. Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape. Science 274 (1996) 1363-1366
25. Hoang T.R., Hammermüller A., Mix E., Kreutzer H.J., Goerlich R., Köhler H., Nizze H., Thiesen H.J., and Ibrahim S.M. A proinflammatory role for Fas in joints of mice with collagen-induced arthritis. Arthritis Res. Ther. 6 (2004) R404-R414
26. Hohlbaum A.M., Saff R.R., and Marshak-Rothstein A. Fas-ligand-iron fist or Achilles' heel?. Clin. Immunol. 103 (2002) 1-6
27. Jones L.L., and Tuszynski M.H. Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors. J. Neurosci. 22 (2002) 4611-4624
28. Karray S., Kress C., Cuvellier S., Hue-Beauvais C., Damotte D., Babinet C., and Levi-Strauss M. Complete loss of Fas ligand gene causes massive lymphoproliferation and early death, indicating a residual activity of gld allele. J. Immunol. 172 (2004) 2118-2125
29. Kang S.M., Hoffmann A., Le D., Springer M.L., Stock P.G., and Blau H.M. Immune response and myoblasts that express Fas ligand. Science 278 (1997) 1322-1324
30. Kennedy N.J., Kataoka T., Tschopp J., and Budd R.C. Caspase activation is required for T cell proliferation. J. Exp. Med. 190 (1999) 1891-1896
31. Kleber S., Sancho-Martinez I., Wiestler B., Beisel A., Gieffers C., Hill O., Thiemann M., Mueller W., Sykora J., Kuhn A., et al. Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell 13 (2008) 235-248
32. Koziol J.A., Maxwell D.A., Fukushima M., Colmerauer M.E., and Pilch Y.H. A distribution-free test for tumor-growth curve analyses with application to an animal tumor immunotherapy experiment. Biometrics 37 (1981) 383-390
33. Lowrance J.H., O'Sullivan F.X., Caver T.E., Waegell W., and Gresham H.D. Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice. J. Exp. Med. 180 (1994) 1693-1703
34. Ma Y., Liu H., Tu-Rapp H., Thiesen H.J., Ibrahim S.M., Cole S.M., and Pope R.M. Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation. Nat. Immunol. 5 (2004) 380-387
35. Mócsai A., Zhou M., Meng F., Tybulewicz V.L., and Lowell C.A. Syk is required for integrin signaling in neutrophils. Immunity 16 (2002) 547-558
36. Nagata S. Fas ligand-induced apoptosis. Annu. Rev. Genet. 33 (1999) 29-55
37. O'Connell J., O'Sullivan G.C., Collins J.K., and Shanahan F. The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand. J. Exp. Med. 184 (1996) 1075-1082
38. Okada S., Nakamura M., Mikami Y., Shimazaki T., Mihara M., Ohsugi Y., Iwamoto Y., Yoshizaki K., Kishimoto T., Toyama Y., and Okano H. Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury. J. Neurosci. Res. 76 (2004) 265-276
39. Park D.R., Thomsen A.R., Frevert C.W., Pham U., Skerrett S.J., Kiener P.A., and Liles W.C. Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages. J. Immunol. 170 (2003) 6209-6216
40. Plemel J.R., Duncan G., Chen K.W., Shannon C., Park S., Sparling J.S., and Tetzlaff W. A graded forceps crush spinal cord injury model in mice. J. Neurotrauma 25 (2008) 350-370
41. Rolls A., Shechter R., and Schwartz M. The bright side of the glial scar in CNS repair. Nat. Rev. Neurosci. 10 (2009) 235-241
42. Sabelko K.A., Kelly K.A., Nahm M.H., Cross A.H., and Russell J.H. Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system. J. Immunol. 159 (1997) 3096-3099
43. Sancho-Martinez I., and Martin-Villalba A. Tyrosine phosphorylation and CD95: a FAScinating switch. Cell Cycle 8 (2009) 838-842
44. Seino K., Kayagaki N., Okumura K., and Yagita H. Antitumor effect of locally produced CD95 ligand. Nat. Med. 3 (1997) 165-170
45. Serrao K.L., Fortenberry J.D., Owens M.L., Harris F.L., and Brown L.A. Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand. Am. J. Physiol. Lung Cell. Mol. Physiol. 280 (2001) L298-L305
46. Shimizu M., Yoshimoto T., Sato M., Morimoto J., Matsuzawa A., and Takeda Y. Roles of CXC chemokines and macrophages in the recruitment of inflammatory cells and tumor rejection induced by Fas/Apo-1 (CD95) ligand-expressing tumor. Int. J. Cancer 114 (2005) 926-935
47. Stirling D.P., and Yong V.W. Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry. J. Neurosci. Res. 86 (2008) 1944-1958
48. Stirling D.P., Liu S., Kubes P., and Yong V.W. Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J. Neurosci. 29 (2009) 753-764
49. Strand S., Hofmann W.J., Hug H., Müller M., Otto G., Strand D., Mariani S.M., Stremmel W., Krammer P.H., and Galle P.R. Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells-a mechanism of immune evasion?. Nat. Med. 2 (1996) 1361-1366
50. Tamir I., and Cambier J.C. Antigen receptor signaling: integration of protein tyrosine kinase functions. Oncogene 17 11 Reviews (1998) 1353-1364
51. Yoshino O., Matsuno H., Nakamura H., Yudoh K., Abe Y., Sawai T., Uzuki M., Yonehara S., and Kimura T. The role of Fas-mediated apoptosis after traumatic spinal cord injury. Spine (Phila Pa 1976) 29 (2004) 1394-1404
52. Zuliani C., Kleber S., Klussmann S., Wenger T., Kenzelmann M., Schreglmann N., Martinez A., del Rio J.A., Soriano E., Vodrazka P., et al. Control of neuronal branching by the death receptor CD95 (Fas/Apo-1). Cell Death Differ. 13 (2006) 31-40