Molecular mechanisms responsible for microglia-derived protection of Sprague-Dawley rat brain cells during in vitro ischemia

Neuroscience Letters

Volumn 373, Issue 2, 2005, Pages 159-164

  Lu, Yen Zhen ^a   Lin, Chi Hsin ^a   Cheng, Fu Chou ^b   Hsueh, Chi Mei ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Astrocyte; GDNF; In vitro ischemia; Microglia; Neuron; TGB 1

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUCOSE; OXYGEN; TRANSFORMING GROWTH FACTOR BETA1; TRYPAN BLUE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN CELL; CELL PROTECTION; CELL TYPE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; ISCHEMIA; MICROGLIA; NERVE CELL; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; SUPERNATANT; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; BRAIN; BRAIN ISCHEMIA; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; MICROGLIA; NERVE GROWTH FACTORS; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; TRANSFORMING GROWTH FACTOR BETA;

EID: 9644272471     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.10.004     Document Type: Article

References (25)

1. K. Abe, and T. Hayashi Expression of the glial cell line-derived neurotrophic factor gene in rat brain after transient MCA occlusion Brain Res. 776 1997 230 234
2. E. Appel, O. Kolman, G. Kazimirsky, P.M. Blumberg, and C. Brodie Regulation of GDNF expression in cultured astrocytes by inflammatory stimuli Glial Cells 8 1997 3309 3312
3. K.A. Ata, F. Lennmyr, K. Funa, Y. Olsson, and A. Terent Expression of transforming growth factor-b1, 2, 3 isoforms and type I and II receptors in acute focal cerebral ischemia: an immunohistochemical study in rat after transient and permanent occlusion of middle cerebral artery Acta Neuropathol. 97 1999 447 455
4. T.C. Brionne, I. Tesseur, E. Masliah, and T. Wyss-Coray Loss of TGF-β1 leads to increased neuronal cell death and microgliosis in mouse brain Neuron 40 2003 1133 1145
5. N. Dunker, N. Schuster, and K. Krieglstein TGF-β modulates programmed cell death in the retina of the developing chick embryo Development 128 2001 1933 1942
6. C.E. Finch, N.J. Laping, T.E. Morgan, N.R. Nichols, and G.M. Pasometto TGF-β1 is an organizer of responses to neurodegeneration J. Cell. Biochem. 53 1993 314 322
7. K.C. Flanders, R.F. Ren, and C.F. Lippa Transforming growth factor-βs in neurodegenerative disease Prog. Neurobiol. 54 1998 71 85
8. P. Franzen, P. ten Dijke, H. Ichijo, H. Yamashita, P. Schulz, C.H. Heldin, and K. Miyazono Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor Cell 75 1993 681 692
9. P. Henrich-Noack, J.H. Prehn, and J. Krrieglstein TGF-β1 protects hippocampal neurons against degeneration caused by transient global ischemia. Dose-response relationship and potential neuroprotective mechanisms Stroke 27 1996 1609 1615
10. S. Honda, K. Nakajima, Y. Nakamura, Y. Imai, and S. Kohsaka Rat primary cultured microglia express glial cell line-derived neurotrophic factor receptors Neurosci. Lett. 275 1999 203 206
11. J.-G.G. Hou, L.-F.H. Lin, and C. Mytilineou Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4- phenylpyridinium J. Neurochem. 66 1996 74 82
12. H. Kitaawa, T. Hayashi, Y. Mitsumoto, N. Koga, Y. Itoyama, and K. Abe Reduction of ischemic brain injury by topical application of glial cell line-derived neurotrophic factor after permanent middle cerebral artery occlusion in rats Stroke 29 1998 1417 1422
13. G.A. Lee, C.-H. Lin, H.-H. Jiang, H.-J. Chao, C.-J. Wu, and C.M. Hsueh Microglia-derived glial cell line-derived neurotrophic factor could protect Sprague-Dawley rat astrocyte from in vitro ischemia-induced damage Neurosci. Lett. 356 2004 111 114
14. E. Lehrmann, R. Kiefer, T. Christensen, K.V. Toyka, J. Ximmer, N.H. Diemer, H.-P. Hartung, and B. Finsen Microglia and macrophages are major sources of locally produced transforming growth factor-b1 after transient middle cerebral artery occlusion in rats Glia 24 1998 437 448
15. H. Miyazaki, K. Nagashima, Y. Okuma, and Y. Nomura Expression of glial cell line-derived neurotrophic factor induced by transient forebrain ischemia in rats Brain Res. 922 2001 165 172
16. N. Olivier, A. Carine, D. Fabian, P. Laurent, T. Eric, V. Denis, and B. Alain Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway J. Neurosci. 21 2001 3024 3033
17. N.A.-M. Pochon, A. Menoud, J.L. Tesng, A.D. Zurn, and P. Aebischer Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization Eur. J. Neurosci. 9 1997 463 471
18. M.S. Rosa, D. Xavier, E. Mario, E. Joaquim, R.B. Jose, and X.C. Joan Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons J. Neurosci. 19 1999 9160 9169
19. K. Salimi, K. Moser, B. Zassler, M. Reindl, N. Embacher, C. Schermer, C. Weis, J. Marksteiner, M. Sawada, and C. Humpel Glial cell line-derived neurotrophic factor enhances survival of GM-CSF dependent rat GMIR-microglial cells Neurosci. Res. 43 2002 221 229
20. M. Shah, D. Revis, S. Herrick, R. Baillie, S. Thorgeirson, M. Ferguson, and A. Roberts Role of elevated plasma transforming growth factor-beta1 levels in wound healing Am. J. Pathol. 154 1999 1115 1124
21. A. Suzumura, M. Sawada, H. Yamamoto, and T. Marunouchi Transforming growth factor-beta suppresses activation and proliferation of microglia in vitro J. Immunol. 151 1993 2150 2158
22. 2+ overload indicates early neuronal injury which precedes staining with viability indicators Brain Res. 607 1993 319 323
23. K. Unsicker, and K. Krieglstein TGF-betas and their roles in the regulation of neuron survival Adv. Exp. Med. Biol. 513 2002 353 374
24. Y. Wang, S.-Z. Lin, A.-L. Chiou, L.R. Williams, and B.J. Hoffer Glial cell line-derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex J. Neurosci. 17 1997 4341 4348
25. T. Wyss-Coray, C. Lin, D.A. Sanan, L. Mucke, and E. Masliah Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice Am. J. Pathol. 156 2000 139 150