Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats

Journal of Neurochemistry

Volumn 88, Issue 6, 2004, Pages 1335-1344

  Bao, Feng ^a   Chen, Yuhua ^a   Dekaban, Gregory A ^a   Weaver, Lynne C ^a  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

Anti CD11d monoclonal antibody; Inducible nitric oxide synthase; Integrin; Macrophage; Myeloperoxidase; Neutrophil

Indexed keywords

3 NITROTYROSINE; ANTIINFLAMMATORY AGENT; CD18 ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTEGRIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD11D; MYELOPEROXIDASE; PROTEIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CONVALESCENCE; DISEASE SEVERITY; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; IMMUNOCYTOCHEMISTRY; LIPID PEROXIDATION; MACROPHAGE; NEUTROPHIL CHEMOTAXIS; NITRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD COMPRESSION; SPINAL CORD INJURY; TREATMENT OUTCOME; WESTERN BLOTTING;

ANIMALIA;

EID: 1642358379     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02240.x     Document Type: Article

References (62)

1. Barone F. C., Hillegass L. M., Price W. J., White R. F., Lee E. V., Feuerstein G. Z., Sarau H. M., Clark R. K. and Griswold D. E. (1991) Polymorphonuclear leukocyte infiltration into cerebral focal ischemic tissue: myeloperoxidase activity assay and histologic verification. J. Neurosci. Res. 29, 336-345.
2. Barten D. M. and Ruddle N. H. (1994) Vascular cell adhesion molecule-1 modulation by tumour necrosis factor in experimental allergic encephalomyelitis. J. Neuroimmunol. 51, 123-133.
3. Bartholdi D. and Schwab M. E. (1995) Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental spinal cord lesion in the rat. Brain Res. 672, 177-186.
4. Beckman J. S. and Koppenol W. H. (1996) Nitric oxide, superoxide, and peroxynitrite, the good, the bad, and ugly. Am. J. Physiol. 271, C1424-C1437.
5. Beckman J. S., Beckman T. W., Chen J., Marshall P. A. and Freeman B. A. (1990) Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl Acad. Sci. USA 87, 1620-1624.
6. Bethea J. R., Nagashima H., Acosta M. C., Briceno C., Gomez F., Marcillo A. E., Loor K., Green J. and Dietrich W. D. (1999) Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats. J. Neurotrauma 16, 851-863.
7. Bevilacqua M. P. (1993) Endothelial-leukocyte adhesion molecules. Annu. Rev. Immunol. 11, 767-804.
8. Biagas K. V., Uhl M. W., Schiding J. K., Nemoto E. M. and Kochanek P. M. (1992) Assessment of posttraumatic polymorphonuclear leukocyte accumulation in rat brain using tissue myeloperoxidase assay and vinblastine treatment. J. Neurotrauma 9, 363-371.
9. Blight A. R. (1985) Delayed demyelination and macrophage invasion: a candidate for. 'secondary' cell damage in spinal cord injury. CNS Trauma 2, 299-315.
10. Blight A. R. (1992) Macrophages and inflammatory damage in spinal cord injury. J. Neurotrauma 9, S83-S91.
11. Bradley P. P., Priebat D. A., Christensen R. D. and Rothstein G. (1982) Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 8, 206-209.
12. Braughler J. M. and Hall E. D. (1989) Central nervous system trauma and stroke. 1. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Rad. Biol. Med. 6, 289-301.
13. Braughler J. M. and Hall E. D. (1992) Involvement of lipid peroxidation in CNS injury. J. Neurotrauma 9, S1-S7.
14. Chikawa T., Ikata T., Katoh S., Hamada Y., Kogure K. and Fukuzawa K. (2001) Preventive effects of lecithinized superoxide dismutase and methylprednisolone on spinal cord injury in rats: transcriptional regulation of inflammatory and neurotrophic genes. J. Neurotrauma 18, 93-103.
15. Clark R. S., Kochanek P. M., Schwarz M. A., Schiding J. K., Turner D. S., Chen M., Carlos T. M. and Watkins S. C. (1996) Inducible nitric oxide synthase expression in cerebrovascular smooth muscle and neutrophils after traumatic brain injury in immature rats. Pediatr Res. 39, 784-790.
16. Fehlings M. G. and Tator C. H. (1995) The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labelled neurons after experimental spinal cord injury. Exp. Neurol. 132, 220-228.
17. Geller D. A., de Vera M. E., Russell D. A., Shapiro R. A., Nussler A. K., Simmons R. L. and Billiar T. R. (1995) A central role for IL-1 beta in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase. IL-1 beta induces hepatic nitric oxide synthesis. J Immunol. 155, 4890-4898.
18. Grayson M. H., Van der Vieren M., Sterbinsky S. A., Michael G. W., Hoffman P. A., Staunton D. E. and Bochner B. S. (1998) Alpha D beta 2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM-1). J. Exp. Med. 188, 2187-2191.
19. Grayson M. H., Van der Vieren M., Sterbinsky S. A., Gallantin W. M., Hoffman P., Staunton D. and Bochner B. S. (1999) Alpha D beta 2 integrin is a ligand for vascular cell adhesion molecule-1. Int. Arch. Allergy Immunol. 118, 263-264.
20. Gris D., Marsh D. R., Oatway M. A., Hamilton E. F., Chen Y., Dekaban G. and Weaver L. C. (2003) Long lasting recovery following early anti-inflammatory treatment after spinal cord injury. J. Neurotrauma 20, 1056.
21. Hogg N. and Leitinger B. (2001) Shape and shift changes related to the function of leukocyte integrins LFA-1 and Mac-1. J. Leukoc. Biol. 69, 893-898.
22. Hurlbert R. J. (2001) The role of steroid in acute spinal cord injury: an evidence-based analysis. Spine 26, S39-S46.
23. Juurlink B. H. and Paterson P. G. (1998) Review of oxidative stress in brain and spinal cord injury: suggestions for pharmacological and nutritional management strategies. J. Spinal Cord Med. 21, 309-334.
24. van Kooyk Y. and Figdor C. G. (1993) Lymphocyte adhesion mediated by integrins. Res. Immunol. 144, 709-722.
25. Kukreja R. C., Kontos H. A., Hess M. L. and Ellis E. F. (1986) PGH synthesis and lipoxygenase generate superoxide in the presence of NADH and NADPH. Circ. Res. 59, 612-619.
26. Leski M. L., Bao F., Wu L., Qian H., Sun D. C. and Liu D. (2001) Protein and DNA oxidation in spinal injury: neurofilaments - an oxidation target. Free Rad. Biol. Med. 30, 613-624.
27. Lewen A., Matz P. and Chan P. H. (2000) Free radical pathways in CNS injury. J Neurotrauma 17, 871-890.
28. Liu D., Sybert T. E., Qian H. and Liu J. (1998) Superoxide production after spinal injury detected by microperfusion of cytochrome c. Free Rad. Biol. Med. 25, 298-304.
29. Liu D., Ling X., Wen J. and Liu J. (2000) The role of reactive nitrogen species in secondary spinal cord injury: formation of nitric oxide, peroxynitrite, and nitrated protein. J. Neurochem. 75, 2144-2154.
30. Mabon P. J., Weaver L. C. and Dekaban G. A. (2000) Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: a potential new anti-inflammatory treatment. Exp. Neurol. 166, 52-64.
31. Macdonald N. J. and Taglialatela G. (2000) Tumor necrosis factor-alpha and nerve growth factor synergistically induce iNOS in pheochromocytoma cells. Neuroreport 11, 3453-3456.
32. MacMicking J., Xie Q. W. and Nathan C. (1997) Nitric oxide and macrophage function. Annu. Rev. Immunol. 15, 323-350.
33. Maiorov D. N., Krenz N. R., Krassioukov A. V. and Weaver L. C. (1997) Role of spinal NMDA and AMPA receptors in episodic hypertension in conscious spinal rats. Am. J. Physiol. 273, H1266-H1274.
34. Means E. D. and Anderson D. K. (1983) Neuronophagia by leukocytes in experimental spinal cord injury. J. Neuropathol. Exp. Neurol. 42, 707-719.
35. ω-nitro-L-arginine-methylester treatment of mice with traumatic brain injury. Eur. J. Pharmacol. 353, 53-57.
36. Miranti C. K. and Brugge J. S. (2002) Sensing the environment: a historical perspective on integrin signal transduction. Nat. Cell Biol. 4, E83-E90.
37. Nakauchi K., Ikata T., Katoh S., Hamada Y., Tsuchiya K. and Fukuzawa K. (1996) Effects of lecithinized superoxide dismutase on rat spinal cord injury. J. Neurotrauma 13, 573-582.
38. Noble L. J., Donovan F., Igarashi T., Goussev S. and Werb Z. (2002) Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events. J. Neurosci. 22, 7526-7535.
39. Ohkawa H., Ohishi N. and Yagi K. (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95, 351-358.
40. Panasenko O. M., Evgiba S. A., Driomina E. S., Sharov V. S., Sergienlo V. I. and Vladimirov Y. A. (1995) Hypochlorite induces lipid peroxidation in blood lipoproteins and phospholipid lysosomes. Free Rad. Biol. Med. 19, 133-140.
41. Petty H. R., Worth R. G. and Todd R. F. III (2002) Interactions of integrins with their partner proteins in leukocyte membranes. Immunol. Res. 25, 75-95.
42. Popovich P. G., Guan Z., Wei. P., Huitinga I., van Rooijen N. and Stokes B. T. (1999) Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp. Neurol. 158, 351-365.
43. Rapalino O., Lazarov-Spiegler O., Agranov E. et al. (1998) Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats. Nat. Med. 4, 814-821.
44. Rivlin A. S. and Tator C. H. (1977) Objective clinical assessment of motor function after experimental spinal cord injury in the rat. J. Neurosci. 47, 577-581.
45. Saville L. R., Simedria F. C., Weaver L. C. and Dekaban G. A. (2002) Treatment of spinal cord injury by using a antibody to the leukocyte integrin alpha D/beta 2 effectively prevents the early infiltration of phagocytes and monocytes/macrophages into the lesion. J Neurotrauma 19, 1352.
46. Schwartz M. A. and Ginsberg M. H. (2002) Networks and crosstalk: integrin signalling spreads. Nat. Cell Biol. 4, E65-E68.
47. Scott G. S., Jakeman L. B., Stokes B. T. and Szabo C. (1999) Peroxynitrite production and activation of poly (adenosine diphosphateribose) synthase in spinal cord injury. Ann. Neurol. 45, 120-124.
48. Shanley T. P., Warner R. L., Crouch L. D., Dietsch G. N., Clark D. L., O'Brien M. M., Gallatin. W. M. and Ward P. A. (1998) Requirements for αd in IgG immune complex-induced rat lung injury. J. Immunol. 160, 1014-1020.
49. Snedecor G. and Cochran W. G. (1989) Statistical Methods. Iowa State University Press, Iowa.
50. Taoka Y. and Okajima K. (1998) Spinal cord injury in the rat. Prog. Neurobiol. 56, 341-358.
51. Taoka Y., Okajima K., Uchiba M., Murakami K., Kushimoto S., Johno M., Naruo M., Okabe H. and Takatsuki K. (1997) Role of neutrophil in spinal cord injury in the rat. Neuroscience 79, 1177-1182.
52. Tator C. H. and Fehlings M. G. (1991) Review of the secondary injury theory of cute spinal cord trauma with emphasis on vascular mechanisms. J. Neurosurg. 75, 15-26.
53. Van der Vieren M., Trong H. L., Wood C. L., Moore P. F., St. John T., Staunton D. E. and Gallatin W. M. (1995) A novel leukointegrin, adb2, binds preferentially to ICAM-3. Immunity 3, 683-690.
54. Van der Vieren M., Crowe D. T., Hoekstra D., Vazeux R., Hoffman P. A., Grayson M. H., Bochner B. S., Gallatin W. M. and Staunton D. E. (1999) The leukocyte integrin αDP2 binds VCAM-1: evidence for a binding interface between I domain and VCAM-1. J. Immunol. 163, 1984-1990.
55. Weaver L. C., Verghese P., Bruce J. C., Fehlings M. G., Krenz N. R. and Marsh D. R. (2001) Autonomic dysreflexia and primary afferent sprouting after clip-compression injury of the rat spinal cord. J. Neurotrauma 18, 1107-1119.
56. Weaver L. C., Marsh D. R., Gris D., Meakin S. O. and Dekaban G. A. (2002) Central mechanisms for autonomic dysreflexia after spinal cord injury. Prog. Brain Res. 137, 83-95.
57. Weiss S. J. (1989) Tissue destruction by neutrophils. N. Engl. J. Med. 320, 365-376.
58. 4 release and polymorphonuclear cell infiltration in spinal cord injury. J. Neurochem. 55, 907-912.
59. Xu J., Kim G. M., Chen S., Yan P., Ahmed S. H., Ku G., Beckman J. S., Xu X. M. and Hsu C. Y. (2001) iNOS and nitrotyrosine expression after spinal cord injury. J. Neurotrauma 18, 523-532.
60. Yang Q., Hamberger A., Hyden H., Wang S., Stigbrand T. and Haglid K. (1995) S-100 beta has a neuronal location in the rat hindbrain revealed by an antigen retrieval method. Brain Res. 696, 49-61.
61. Young W. (1993) Secondary injury mechanisms in acute spinal cord injury. J. Emerg. Med. 11, 13-22.
62. Zhang Z. and Guth L. (1997) Experimental spinal cord injury: Wallarian degeneration in the dorsal column is followed by revascularization, glial proliferation, and nerve regeneration. Exp. Neurol. 147, 159-171.