Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion

Brain, Behavior, and Immunity

Volumn 24, Issue 4, 2010, Pages 540-553

  Pineau, Isabelle ^a   Sun, Libo ^a   Bastien, Dominic ^a   Lacroix, Steve ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Central nervous system; Chemokine; Cytokine; Inflammasome; Inflammation; Interleukin 1; Macrophage; Regeneration; Spinal cord injury; Wallerian degeneration

Indexed keywords

INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR TYPE I; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOID DIFFERENTIATION FACTOR 88; POTASSIUM CHANNEL; CCL2 PROTEIN, MOUSE; CXCL1 CHEMOKINE; CXCL1 PROTEIN, MOUSE; CXCL2 CHEMOKINE; CXCL2 PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENCEPHALITIS; FEMALE; IMMUNOCOMPETENT CELL; MICROGLIA; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; ANIMAL; C3H MOUSE; C57BL MOUSE; CYTOLOGY; DEFICIENCY; DISEASE MODEL; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOLOGY; IN SITU HYBRIDIZATION; KNOCKOUT MOUSE; METABOLISM; POLYMERASE CHAIN REACTION; SPINAL CORD; TIME;

ANIMALS; ASTROCYTES; CHEMOKINE CCL2; CHEMOKINE CXCL1; CHEMOKINE CXCL2; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHILS; POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-1 TYPE I; RNA, MESSENGER; SPINAL CORD; SPINAL CORD INJURIES; TIME FACTORS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 77950521720     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2009.11.007     Document Type: Article

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