-
1
-
-
79953279646
-
Genome-wide association studies for discovery of genes involved in asthma
-
Akhabir L, Sandford AJ. Genome-wide association studies for discovery of genes involved in asthma. Respirology 2011;16:396-406.
-
(2011)
Respirology
, vol.16
, pp. 396-406
-
-
Akhabir, L.1
Sandford, A.J.2
-
2
-
-
50849120030
-
Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus
-
Weidinger S, et al. Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. PLoS Genet 2008;4:e1000166.
-
(2008)
PLoS Genet
, vol.4
-
-
Weidinger, S.1
-
3
-
-
67651162340
-
Immunobiology of asthma
-
Hamid Q, Tulic M. Immunobiology of asthma. Annu Rev Physiol 2009;71:489-507.
-
(2009)
Annu Rev Physiol
, vol.71
, pp. 489-507
-
-
Hamid, Q.1
Tulic, M.2
-
4
-
-
77958112424
-
Allergic rhinitis: pathophysiology
-
Broide DH. Allergic rhinitis: pathophysiology. Allergy Asthma Proc 2010;31:370-374.
-
(2010)
Allergy Asthma Proc
, vol.31
, pp. 370-374
-
-
Broide, D.H.1
-
5
-
-
73149091880
-
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2009
-
Sicherer SH, Leung DY. Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2009. J Allergy Clin Immunol 2010;125:85-97.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 85-97
-
-
Sicherer, S.H.1
Leung, D.Y.2
-
6
-
-
33748317870
-
Asthma and current intestinal parasite infection: systematic review and meta-analysis
-
Leonardi-Bee J, Pritchard D, Britton J. Asthma and current intestinal parasite infection: systematic review and meta-analysis. Am J Respir Crit Care Med 2006;174:514-523.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 514-523
-
-
Leonardi-Bee, J.1
Pritchard, D.2
Britton, J.3
-
7
-
-
58149232412
-
Do helminth parasites protect against atopy and allergic disease?
-
Flohr C, Quinnell RJ, Britton J. Do helminth parasites protect against atopy and allergic disease? Clin Exp Allergy 2009;39:20-32.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 20-32
-
-
Flohr, C.1
Quinnell, R.J.2
Britton, J.3
-
8
-
-
77956826692
-
The relationship of airway hyperresponsiveness and airway inflammation: airway hyperresponsiveness in asthma: its measurement and clinical significance
-
Busse WW. The relationship of airway hyperresponsiveness and airway inflammation: airway hyperresponsiveness in asthma: its measurement and clinical significance. Chest 2010;138:4S-10S.
-
(2010)
Chest
, vol.138
-
-
Busse, W.W.1
-
9
-
-
33644752698
-
Stem cell factor and its receptor c-Kit as targets for inflammatory diseases
-
Reber L, Da Silva CA, Frossard N. Stem cell factor and its receptor c-Kit as targets for inflammatory diseases. Eur J Pharmacol 2006;533:327-340.
-
(2006)
Eur J Pharmacol
, vol.533
, pp. 327-340
-
-
Reber, L.1
Da Silva, C.A.2
Frossard, N.3
-
10
-
-
49449109223
-
Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders
-
Jensen BM, Akin C, Gilfillan AM. Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders. Br J Pharmacol 2008;154:1572-1582.
-
(2008)
Br J Pharmacol
, vol.154
, pp. 1572-1582
-
-
Jensen, B.M.1
Akin, C.2
Gilfillan, A.M.3
-
11
-
-
35548983087
-
Airway hyperresponsiveness and bronchial mucosal inflammation in T cell peptide-induced asthmatic reactions in atopic subjects
-
Ali FR, Kay AB, Larche M. Airway hyperresponsiveness and bronchial mucosal inflammation in T cell peptide-induced asthmatic reactions in atopic subjects. Thorax 2007;62:750-757.
-
(2007)
Thorax
, vol.62
, pp. 750-757
-
-
Ali, F.R.1
Kay, A.B.2
Larche, M.3
-
12
-
-
40049104892
-
Immunology of asthma and chronic obstructive pulmonary disease
-
Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Immunol Rev 2008;8:183-192.
-
(2008)
Nat Immunol Rev
, vol.8
, pp. 183-192
-
-
Barnes, P.J.1
-
13
-
-
77956366626
-
The role of dendritic and epithelial cells as master regulators of allergic airway inflammation
-
Lambrecht BN, Hammad H. The role of dendritic and epithelial cells as master regulators of allergic airway inflammation. Lancet 2010;376:835-843.
-
(2010)
Lancet
, vol.376
, pp. 835-843
-
-
Lambrecht, B.N.1
Hammad, H.2
-
14
-
-
67649216604
-
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response
-
Sokol CL, Chu NQ, Yu S, Nish SA, Laufer TM, Medzhitov R. Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat Immunol 2009;10:713-720.
-
(2009)
Nat Immunol
, vol.10
, pp. 713-720
-
-
Sokol, C.L.1
Chu, N.Q.2
Yu, S.3
Nish, S.A.4
Laufer, T.M.5
Medzhitov, R.6
-
15
-
-
67649227119
-
Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells
-
Yoshimoto T, et al. Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells. Nat Immunol 2009;10:706-712.
-
(2009)
Nat Immunol
, vol.10
, pp. 706-712
-
-
Yoshimoto, T.1
-
16
-
-
77954133073
-
Basophils are potent antigen-presenting cells that selectively induce Th2 cells
-
Nakanishi K. Basophils are potent antigen-presenting cells that selectively induce Th2 cells. Eur J Immunol 2010;40:1836-1842.
-
(2010)
Eur J Immunol
, vol.40
, pp. 1836-1842
-
-
Nakanishi, K.1
-
17
-
-
78049277883
-
Innate immune cell populations function as initiators and effectors in Th2 cytokine responses
-
Saenz SA, Noti M, Artis D. Innate immune cell populations function as initiators and effectors in Th2 cytokine responses. Trends Immunol 2010;31:407-413.
-
(2010)
Trends Immunol
, vol.31
, pp. 407-413
-
-
Saenz, S.A.1
Noti, M.2
Artis, D.3
-
18
-
-
78649516124
-
Functions of T cells in asthma: more than just T(H)2 cells
-
Lloyd CM, Hessel EM. Functions of T cells in asthma: more than just T(H)2 cells. Nat Rev Immunol 2010;10:838-848.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 838-848
-
-
Lloyd, C.M.1
Hessel, E.M.2
-
19
-
-
67650502393
-
Th9 and allergic disease
-
Soroosh P, Doherty TA. Th9 and allergic disease. Immunology 2009;127:450-458.
-
(2009)
Immunology
, vol.127
, pp. 450-458
-
-
Soroosh, P.1
Doherty, T.A.2
-
21
-
-
77951717543
-
Role of Treg in immune regulation of allergic diseases
-
Palomares O, Yaman G, Azkur AK, Akkoc T, Akdis M, Akdis CA. Role of Treg in immune regulation of allergic diseases. Eur J Immunol 2010;40:1232-1240.
-
(2010)
Eur J Immunol
, vol.40
, pp. 1232-1240
-
-
Palomares, O.1
Yaman, G.2
Azkur, A.K.3
Akkoc, T.4
Akdis, M.5
Akdis, C.A.6
-
22
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness and the late asthmatic response
-
Leckie MJ, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness and the late asthmatic response. Lancet 2000;356:2144-2148.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
-
23
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-984.
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
-
26
-
-
0041854718
-
Eosinophilic bronchitis: clinical features, management and pathogenesis
-
Birring SS, Berry M, Brightling CE, Pavord ID. Eosinophilic bronchitis: clinical features, management and pathogenesis. Am J Respir Med 2003;2:169-173.
-
(2003)
Am J Respir Med
, vol.2
, pp. 169-173
-
-
Birring, S.S.1
Berry, M.2
Brightling, C.E.3
Pavord, I.D.4
-
27
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair P, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009;360:985-993.
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
-
28
-
-
77952084612
-
B lymphocytes in inflammatory airway diseases
-
Drolet JP, Frangie H, Guay J, Hajoui O, Hamid Q, Mazer BD. B lymphocytes in inflammatory airway diseases. Clin Exp Allergy 2010;40:841-849.
-
(2010)
Clin Exp Allergy
, vol.40
, pp. 841-849
-
-
Drolet, J.P.1
Frangie, H.2
Guay, J.3
Hajoui, O.4
Hamid, Q.5
Mazer, B.D.6
-
29
-
-
0034222961
-
Local synthesis of epsilon germline gene transcripts, IL-4, and IL-13 in allergic nasal mucosa after ex vivo allergen exposure
-
Cameron L, et al. Local synthesis of epsilon germline gene transcripts, IL-4, and IL-13 in allergic nasal mucosa after ex vivo allergen exposure. J Allergy Clin Immunol 2000;106:46-52.
-
(2000)
J Allergy Clin Immunol
, vol.106
, pp. 46-52
-
-
Cameron, L.1
-
30
-
-
33845952641
-
Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma
-
Takhar P, et al. Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma. J Allergy Clin Immunol 2007;119:213-218.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 213-218
-
-
Takhar, P.1
-
31
-
-
51549098344
-
B cell antigen presentation promotes Th2 responses and immunopathology during chronic allergic lung disease
-
Lindell DM, Berlin AA, Schaller MA, Lukacs NW. B cell antigen presentation promotes Th2 responses and immunopathology during chronic allergic lung disease. PLoS ONE 2008;3:e3129.
-
(2008)
PLoS ONE
, vol.3
-
-
Lindell, D.M.1
Berlin, A.A.2
Schaller, M.A.3
Lukacs, N.W.4
-
32
-
-
59449106149
-
Local release of B cell-activating factor of the TNF family after segmental allergen challenge of allergic subjects
-
Kato A, Xiao H, Chustz RT, Liu MC, Schleimer RP. Local release of B cell-activating factor of the TNF family after segmental allergen challenge of allergic subjects. J Allergy Clin Immunol 2009;123:369-375.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 369-375
-
-
Kato, A.1
Xiao, H.2
Chustz, R.T.3
Liu, M.C.4
Schleimer, R.P.5
-
33
-
-
0345734195
-
Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucocorticoids
-
Cundall M, Sun Y, Miranda C, Trudeau JB, Barnes S, Wenzel SE. Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucocorticoids. J Allergy Clin Immunol 2003;112:1064-1071.
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 1064-1071
-
-
Cundall, M.1
Sun, Y.2
Miranda, C.3
Trudeau, J.B.4
Barnes, S.5
Wenzel, S.E.6
-
34
-
-
0032698182
-
Neutrophilic inflammation in severe persistent asthma
-
Jatakanon A, Uasaf C, Maziak W, Lim S, Chung KF, Barnes PJ. Neutrophilic inflammation in severe persistent asthma. Am J Respir Crit Care Med 1999;160:1532-1539.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1532-1539
-
-
Jatakanon, A.1
Uasaf, C.2
Maziak, W.3
Lim, S.4
Chung, K.F.5
Barnes, P.J.6
-
35
-
-
33645101537
-
Inflammatory subtypes in asthma: assessment and identification using induced sputum
-
Simpson JL, Scott R, Boyle MJ, Gibson PG. Inflammatory subtypes in asthma: assessment and identification using induced sputum. Respirology 2006;11:54-61.
-
(2006)
Respirology
, vol.11
, pp. 54-61
-
-
Simpson, J.L.1
Scott, R.2
Boyle, M.J.3
Gibson, P.G.4
-
37
-
-
78349269946
-
Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD
-
Doe C, et al. Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest 2010;138:1140-1147.
-
(2010)
Chest
, vol.138
, pp. 1140-1147
-
-
Doe, C.1
-
38
-
-
0042530486
-
Allergic and nonallergic forms of atopic diseases
-
Novak N, Bieber T. Allergic and nonallergic forms of atopic diseases. J Allergy Clin Immunol 2003;112:252-262.
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 252-262
-
-
Novak, N.1
Bieber, T.2
-
39
-
-
0033772971
-
Elevation of total serum immunoglobulin E is associated with asthma in nonallergic individuals
-
Beeh KM, Ksoll M, Buhl R. Elevation of total serum immunoglobulin E is associated with asthma in nonallergic individuals. Eur Respir J 2000;16:609-614.
-
(2000)
Eur Respir J
, vol.16
, pp. 609-614
-
-
Beeh, K.M.1
Ksoll, M.2
Buhl, R.3
-
40
-
-
34249740696
-
Role of staphylococcal superantigens in airway disease
-
Bachert C, Gevaert P, Zhang N, van Zele T, Perez-Novo C. Role of staphylococcal superantigens in airway disease. Chem Immunol Allergy 2007;93:214-236.
-
(2007)
Chem Immunol Allergy
, vol.93
, pp. 214-236
-
-
Bachert, C.1
Gevaert, P.2
Zhang, N.3
van Zele, T.4
Perez-Novo, C.5
-
41
-
-
38049129665
-
Role of staphylococcal superantigens in upper airway disease
-
Bachert C, Zhang N, Patou J, van Zele T, Gevaert P. Role of staphylococcal superantigens in upper airway disease. Curr Opin Allergy Clin Immunol 2008;8:34-38.
-
(2008)
Curr Opin Allergy Clin Immunol
, vol.8
, pp. 34-38
-
-
Bachert, C.1
Zhang, N.2
Patou, J.3
van Zele, T.4
Gevaert, P.5
-
42
-
-
0035038554
-
Total and specific IgE in nasal polyps is related to local eosinophilic inflammation
-
Bachert C, Gevaert P, Holtappels G, Johansson SG, Van Cauwenberge P. Total and specific IgE in nasal polyps is related to local eosinophilic inflammation. J Allergy Clin Immunol 2001;107:607-614.
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 607-614
-
-
Bachert, C.1
Gevaert, P.2
Holtappels, G.3
Johansson, S.G.4
Van Cauwenberge, P.5
-
43
-
-
34249728822
-
The allergic march from Staphylococcus aureus superantigens to immunoglobulin E
-
Gould HJ, Takhar P, Harries HE, Chevretton E, Sutton BJ. The allergic march from Staphylococcus aureus superantigens to immunoglobulin E. Chem Immunol Allergy 2007;93:106-136.
-
(2007)
Chem Immunol Allergy
, vol.93
, pp. 106-136
-
-
Gould, H.J.1
Takhar, P.2
Harries, H.E.3
Chevretton, E.4
Sutton, B.J.5
-
44
-
-
33750369712
-
Role of staphylococcal superantigen-specific IgE antibodies in aspirin-intolerant asthma
-
Lee JY, et al. Role of staphylococcal superantigen-specific IgE antibodies in aspirin-intolerant asthma. Allergy Asthma Proc 2006;27:341-346.
-
(2006)
Allergy Asthma Proc
, vol.27
, pp. 341-346
-
-
Lee, J.Y.1
-
45
-
-
53649083007
-
Human mast cell activation by Staphylococcus aureus: interleukin-8 and tumor necrosis factor alpha release and the role of Toll-like receptor 2 and CD48 molecules
-
Rocha-de-Souza CM, Berent-Maoz B, Mankuta D, Moses AE, Levi-Schaffer F. Human mast cell activation by Staphylococcus aureus: interleukin-8 and tumor necrosis factor alpha release and the role of Toll-like receptor 2 and CD48 molecules. Infect Immun 2008;76:4489-4497.
-
(2008)
Infect Immun
, vol.76
, pp. 4489-4497
-
-
Rocha-de-Souza, C.M.1
Berent-Maoz, B.2
Mankuta, D.3
Moses, A.E.4
Levi-Schaffer, F.5
-
46
-
-
67650418178
-
Intrinsic asthma: not so different from allergic asthma but driven by superantigens?
-
Barnes PJ. Intrinsic asthma: not so different from allergic asthma but driven by superantigens? Clin Exp Allergy 2009;39:1145-1151.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 1145-1151
-
-
Barnes, P.J.1
-
47
-
-
52049123299
-
The bacterial superantigen and superantigen-like proteins
-
Fraser JD, Proft T. The bacterial superantigen and superantigen-like proteins. Immunol Rev 2008;225:226-243.
-
(2008)
Immunol Rev
, vol.225
, pp. 226-243
-
-
Fraser, J.D.1
Proft, T.2
-
48
-
-
0345222473
-
Airway exposure to bacterial superantigen (SEB) induces lymphocyte-dependent airway inflammation associated with increased airway responsiveness--a model for non-allergic asthma
-
Herz U, et al. Airway exposure to bacterial superantigen (SEB) induces lymphocyte-dependent airway inflammation associated with increased airway responsiveness--a model for non-allergic asthma. Eur J Immunol 1999;29:1021-1031.
-
(1999)
Eur J Immunol
, vol.29
, pp. 1021-1031
-
-
Herz, U.1
-
49
-
-
24944571691
-
Superantigens and chronic rhinosinusitis: detection of staphylococcal exotoxins in nasal polyps
-
Seiberling KA, et al. Superantigens and chronic rhinosinusitis: detection of staphylococcal exotoxins in nasal polyps. Laryngoscope 2005;115:1580-1585.
-
(2005)
Laryngoscope
, vol.115
, pp. 1580-1585
-
-
Seiberling, K.A.1
-
50
-
-
78650035276
-
Mucosal tissue polyclonal IgE is functional in response to allergen and SEB
-
Zhang N, et al. Mucosal tissue polyclonal IgE is functional in response to allergen and SEB. Allergy 2011;66:141-148.
-
(2011)
Allergy
, vol.66
, pp. 141-148
-
-
Zhang, N.1
-
51
-
-
51549095640
-
Inhalation of Staphylococcus aureus enterotoxin A induces IFN-gamma and CD8 T cell-dependent airway and interstitial lung pathology in mice
-
Muralimohan G, Rossi RJ, Guernsey LA, Thrall RS, Vella AT. Inhalation of Staphylococcus aureus enterotoxin A induces IFN-gamma and CD8 T cell-dependent airway and interstitial lung pathology in mice. J Immunol 2008;181:3698-3705.
-
(2008)
J Immunol
, vol.181
, pp. 3698-3705
-
-
Muralimohan, G.1
Rossi, R.J.2
Guernsey, L.A.3
Thrall, R.S.4
Vella, A.T.5
-
52
-
-
38149126990
-
Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps
-
Patou J, Gevaert P, van Zele T, Holtappels G, Van Cauwenberge P, Bachert C. Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps. J Allergy Clin Immunol 2008;121:110-115.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 110-115
-
-
Patou, J.1
Gevaert, P.2
van Zele, T.3
Holtappels, G.4
Van Cauwenberge, P.5
Bachert, C.6
-
53
-
-
0034020396
-
Clonal expansion of T cells infiltrating in the airways of non-atopic asthmatics
-
Umibe T, et al. Clonal expansion of T cells infiltrating in the airways of non-atopic asthmatics. Clin Exp Immunol 2000;119:390-397.
-
(2000)
Clin Exp Immunol
, vol.119
, pp. 390-397
-
-
Umibe, T.1
-
54
-
-
1942531991
-
T regulatory cells in atopic dermatitis and subversion of their activity by superantigens
-
Ou LS, Goleva E, Hall C, Leung DY. T regulatory cells in atopic dermatitis and subversion of their activity by superantigens. J Allergy Clin Immunol 2004;113:756-763.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 756-763
-
-
Ou, L.S.1
Goleva, E.2
Hall, C.3
Leung, D.Y.4
-
55
-
-
33644777428
-
Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes
-
Cardona ID, Goleva E, Ou LS, Leung DY. Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes. J Allergy Clin Immunol 2006;117:688-695.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 688-695
-
-
Cardona, I.D.1
Goleva, E.2
Ou, L.S.3
Leung, D.Y.4
-
56
-
-
7944220552
-
Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway
-
Li LB, Goleva E, Hall CF, Ou LS, Leung DY. Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway. J Allergy Clin Immunol 2004;114:1059-1069.
-
(2004)
J Allergy Clin Immunol
, vol.114
, pp. 1059-1069
-
-
Li, L.B.1
Goleva, E.2
Hall, C.F.3
Ou, L.S.4
Leung, D.Y.5
-
57
-
-
38449105934
-
Cutting edge: TCR revision affects predominantly Foxp3 cells and skews them toward the Th17 lineage
-
Zehn D, Bevan MJ, Fink PJ. Cutting edge: TCR revision affects predominantly Foxp3 cells and skews them toward the Th17 lineage. J Immunol 2007;179:5653-5657.
-
(2007)
J Immunol
, vol.179
, pp. 5653-5657
-
-
Zehn, D.1
Bevan, M.J.2
Fink, P.J.3
-
58
-
-
58149131262
-
IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response
-
Eyerich K, et al. IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J Allergy Clin Immunol 2009;123:59-66.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 59-66
-
-
Eyerich, K.1
-
59
-
-
0028892385
-
Autoimmune phenomena in bronchial asthma with special reference to aspirin intolerance
-
Szczeklik A, Nizankowska E, Serafin A, Dyczek A, Duplaga M, Musial J. Autoimmune phenomena in bronchial asthma with special reference to aspirin intolerance. Am J Respir Crit Care Med 1995;152:1753-1756.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 1753-1756
-
-
Szczeklik, A.1
Nizankowska, E.2
Serafin, A.3
Dyczek, A.4
Duplaga, M.5
Musial, J.6
-
60
-
-
45349086714
-
Autoantibodies to the high-affinity IgE receptor in patients with asthma
-
Sun RS, Chen XH, Liu RQ, Cheng TM, Ran XZ, Yang T. Autoantibodies to the high-affinity IgE receptor in patients with asthma. Asian Pac J Allergy Immunol 2008;26:19-22.
-
(2008)
Asian Pac J Allergy Immunol
, vol.26
, pp. 19-22
-
-
Sun, R.S.1
Chen, X.H.2
Liu, R.Q.3
Cheng, T.M.4
Ran, X.Z.5
Yang, T.6
-
61
-
-
0036606245
-
Identification of cytokeratin 18 as a bronchial epithelial autoantigen associated with nonallergic asthma
-
Nahm DH, et al. Identification of cytokeratin 18 as a bronchial epithelial autoantigen associated with nonallergic asthma. Am J Respir Crit Care Med 2002;165:1536-1539.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1536-1539
-
-
Nahm, D.H.1
-
62
-
-
33746579193
-
Identification of alpha-enolase as an autoantigen associated with severe asthma
-
Nahm DH, Lee KH, Shin JY, Ye YM, Kang Y, Park HS. Identification of alpha-enolase as an autoantigen associated with severe asthma. J Allergy Clin Immunol 2006;118:376-381.
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 376-381
-
-
Nahm, D.H.1
Lee, K.H.2
Shin, J.Y.3
Ye, Y.M.4
Kang, Y.5
Park, H.S.6
-
63
-
-
67651251805
-
Increased IgG Antibody-Induced Cytotoxicity Against Airway Epithelial Cells in Patients with Nonallergic Asthma
-
Kwon B, Lee HA, Choi GS, Ye YM, Nahm DH, Park HS. Increased IgG Antibody-Induced Cytotoxicity Against Airway Epithelial Cells in Patients with Nonallergic Asthma. J Clin Immunol 2009;29:517-523.
-
(2009)
J Clin Immunol
, vol.29
, pp. 517-523
-
-
Kwon, B.1
Lee, H.A.2
Choi, G.S.3
Ye, Y.M.4
Nahm, D.H.5
Park, H.S.6
-
65
-
-
0031905895
-
Inflammatory mediators in naturally occurring rhinitis
-
Wilson SJ, Lau L, Howarth PH. Inflammatory mediators in naturally occurring rhinitis. Clin Exp Allergy 1998;28:220-227.
-
(1998)
Clin Exp Allergy
, vol.28
, pp. 220-227
-
-
Wilson, S.J.1
Lau, L.2
Howarth, P.H.3
-
66
-
-
0035153766
-
Cellular and immunologic mechanisms in atopic dermatitis
-
Leung DY, Soter NA. Cellular and immunologic mechanisms in atopic dermatitis. J Am Acad Dermatol 2001;44:S1-S12.
-
(2001)
J Am Acad Dermatol
, vol.44
-
-
Leung, D.Y.1
Soter, N.A.2
-
67
-
-
0030710093
-
Effects of antihistamines in adult asthma: a meta-analysis of clinical trials
-
van Ganse E, Kaufman L, Derde MP, Yernault JC, Delaunois L. Effects of antihistamines in adult asthma: a meta-analysis of clinical trials. Eur Respir J 1997;10:2216-2224.
-
(1997)
Eur Respir J
, vol.10
, pp. 2216-2224
-
-
van Ganse, E.1
Kaufman, L.2
Derde, M.P.3
Yernault, J.C.4
Delaunois, L.5
-
69
-
-
53849134126
-
Eicosanoids in asthma, allergic inflammation, and host defense
-
Boyce JA. Eicosanoids in asthma, allergic inflammation, and host defense. Curr Mol Med 2008;8:335-349.
-
(2008)
Curr Mol Med
, vol.8
, pp. 335-349
-
-
Boyce, J.A.1
-
70
-
-
4544296118
-
T-cell trafficking in asthma: lipid mediators grease the way
-
Luster AD, Tager AM. T-cell trafficking in asthma: lipid mediators grease the way. Nat Rev Immunol 2004;4:711-724.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 711-724
-
-
Luster, A.D.1
Tager, A.M.2
-
71
-
-
33644545461
-
CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma
-
Gelfand EW, Dakhama A. CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma. J Allergy Clin Immunol 2006;117:577-582.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 577-582
-
-
Gelfand, E.W.1
Dakhama, A.2
-
72
-
-
77249097474
-
Blockade of airway inflammation and hyperresponsiveness by inhibition of BLT2, a low-affinity leukotriene B4 receptor
-
Cho KJ, et al. Blockade of airway inflammation and hyperresponsiveness by inhibition of BLT2, a low-affinity leukotriene B4 receptor. Am J Respir Cell Mol Biol 2010;42:294-303.
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, pp. 294-303
-
-
Cho, K.J.1
-
73
-
-
59549107791
-
Role of prostaglandin D(2) and its receptors in the pathophysiology of asthma
-
Oguma T, Asano K, Ishizaka A. Role of prostaglandin D(2) and its receptors in the pathophysiology of asthma. Allergol Int 2008;57:307-312.
-
(2008)
Allergol Int
, vol.57
, pp. 307-312
-
-
Oguma, T.1
Asano, K.2
Ishizaka, A.3
-
74
-
-
33947726053
-
Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases
-
Pettipher R, Hansel TT, Armer R. Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases. Nat Rev Drug Discov 2007;6:313-325.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 313-325
-
-
Pettipher, R.1
Hansel, T.T.2
Armer, R.3
-
75
-
-
77953598665
-
CRTH2 and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases
-
Schuligoi R, et al. CRTH2 and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases. Pharmacology 2010;85:372-382.
-
(2010)
Pharmacology
, vol.85
, pp. 372-382
-
-
Schuligoi, R.1
-
77
-
-
10044235066
-
Isoprostanes: markers and mediators of oxidative stress
-
Montuschi P, Barnes PJ, Roberts LJ. Isoprostanes: markers and mediators of oxidative stress. FASEB J 2004;18:1791-1800.
-
(2004)
FASEB J
, vol.18
, pp. 1791-1800
-
-
Montuschi, P.1
Barnes, P.J.2
Roberts, L.J.3
-
78
-
-
38649115964
-
Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells
-
Feltenmark S, et al. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells. Proc Natl Acad Sci U S A 2008;105:680-685.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 680-685
-
-
Feltenmark, S.1
-
79
-
-
55849148482
-
Cytokine networks in asthma and chronic obstructive pulmonary disease
-
Barnes PJ. Cytokine networks in asthma and chronic obstructive pulmonary disease. J Clin Invest 2008;118:3546-3556.
-
(2008)
J Clin Invest
, vol.118
, pp. 3546-3556
-
-
Barnes, P.J.1
-
80
-
-
77649198441
-
Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma
-
Oh CK, Geba GP, Molfino N. Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma. Eur Respir Rev 2010;19:46-54.
-
(2010)
Eur Respir Rev
, vol.19
, pp. 46-54
-
-
Oh, C.K.1
Geba, G.P.2
Molfino, N.3
-
81
-
-
77950271175
-
A review of treatment with mepolizumab, an anti-IL-5 mAb, in hypereosinophilic syndromes and asthma
-
Busse WW, Ring J, Huss-Marp J, Kahn JE. A review of treatment with mepolizumab, an anti-IL-5 mAb, in hypereosinophilic syndromes and asthma. J Allergy Clin Immunol 2010;125:803-813.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 803-813
-
-
Busse, W.W.1
Ring, J.2
Huss-Marp, J.3
Kahn, J.E.4
-
82
-
-
62549084077
-
A randomized, double-blind, placebo-controlled study of TNF-a blockade in severe persistent asthma
-
Wenzel SE, et al. A randomized, double-blind, placebo-controlled study of TNF-a blockade in severe persistent asthma. Am J Respir Crit Care Med 2009;179:549-558.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 549-558
-
-
Wenzel, S.E.1
-
83
-
-
33344455022
-
Thymic stromal lymphopoietin: master switch for allergic inflammation
-
Liu YJ. Thymic stromal lymphopoietin: master switch for allergic inflammation. J Exp Med 2006;203:269-273.
-
(2006)
J Exp Med
, vol.203
, pp. 269-273
-
-
Liu, Y.J.1
-
84
-
-
77949784970
-
Sensing the outside world: TSLP regulates barrier immunity
-
Ziegler SF, Artis D. Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol 2010;11:289-293.
-
(2010)
Nat Immunol
, vol.11
, pp. 289-293
-
-
Ziegler, S.F.1
Artis, D.2
-
85
-
-
20444365526
-
Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity
-
Ying S, et al. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J Immunol 2005;174:8183-8190.
-
(2005)
J Immunol
, vol.174
, pp. 8183-8190
-
-
Ying, S.1
-
86
-
-
61649123362
-
Overexpression of thymic stromal lymphopoietin in allergic rhinitis
-
Mou Z, et al. Overexpression of thymic stromal lymphopoietin in allergic rhinitis. Acta Otolaryngol 2009;129:297-301.
-
(2009)
Acta Otolaryngol
, vol.129
, pp. 297-301
-
-
Mou, Z.1
-
87
-
-
60849122545
-
Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma
-
Zhang Z, et al. Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma. Proc Natl Acad Sci USA 2009;106:1536-1541.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1536-1541
-
-
Zhang, Z.1
-
88
-
-
67649213505
-
IL-25: a key requirement for the regulation of type-2 immunity
-
Barlow JL, McKenzie AN. IL-25: a key requirement for the regulation of type-2 immunity. Biofactors 2009;35:178-182.
-
(2009)
Biofactors
, vol.35
, pp. 178-182
-
-
Barlow, J.L.1
McKenzie, A.N.2
-
90
-
-
78650634417
-
IL-33 mediates inflammatory responses in human lung tissue cells
-
Yagami A, et al. IL-33 mediates inflammatory responses in human lung tissue cells. J Immunol 2010;185:5743-5750.
-
(2010)
J Immunol
, vol.185
, pp. 5743-5750
-
-
Yagami, A.1
-
91
-
-
75549085516
-
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation
-
Kurowska-Stolarska M, et al. IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol 2009;183:6469-6477.
-
(2009)
J Immunol
, vol.183
, pp. 6469-6477
-
-
Kurowska-Stolarska, M.1
-
92
-
-
77649271174
-
Increased IL-33 expression by epithelial cells in bronchial asthma
-
Prefontaine D, et al. Increased IL-33 expression by epithelial cells in bronchial asthma. J Allergy Clin Immunol 2010;125:752-754.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 752-754
-
-
Prefontaine, D.1
-
93
-
-
67649852593
-
The cytokine interleukin-33 mediates anaphylactic shock
-
Pushparaj PN, et al. The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci U S A 2009;106:9773-9778.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9773-9778
-
-
Pushparaj, P.N.1
-
94
-
-
77957787918
-
IL-33 is produced by mast cells and regulates IgE-dependent inflammation
-
Hsu CL, Neilsen CV, Bryce PJ. IL-33 is produced by mast cells and regulates IgE-dependent inflammation. PLoS ONE 2010;5:e11944.
-
(2010)
PLoS ONE
, vol.5
-
-
Hsu, C.L.1
Neilsen, C.V.2
Bryce, P.J.3
-
96
-
-
0033647212
-
Non-redundant functional groups of chemokines operate in a coordinate manner during the inflammatory response in the lung
-
Gutierrez-Ramos JC, Lloyd C, Kapsenberg ML, Gonzalo JA, Coyle AJ. Non-redundant functional groups of chemokines operate in a coordinate manner during the inflammatory response in the lung. Immunol Rev 2000;177:31-42.
-
(2000)
Immunol Rev
, vol.177
, pp. 31-42
-
-
Gutierrez-Ramos, J.C.1
Lloyd, C.2
Kapsenberg, M.L.3
Gonzalo, J.A.4
Coyle, A.J.5
-
98
-
-
77952783111
-
Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients
-
Vijayanand P, et al. Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients. J Immunol 2010;184:4568-4574.
-
(2010)
J Immunol
, vol.184
, pp. 4568-4574
-
-
Vijayanand, P.1
-
99
-
-
0001058084
-
Increased 8-Isoprostane, a marker of oxidative stress, in exhaled condensates of asthmatic patients
-
Montuschi P, et al. Increased 8-Isoprostane, a marker of oxidative stress, in exhaled condensates of asthmatic patients. Am J Respir Crit Care Med 1999;160:216-220.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 216-220
-
-
Montuschi, P.1
-
101
-
-
0034110543
-
Reactive oxygen species in asthma
-
Barnes PJ. Reactive oxygen species in asthma. Eur Respir Rev 2000;10:240-243.
-
(2000)
Eur Respir Rev
, vol.10
, pp. 240-243
-
-
Barnes, P.J.1
-
103
-
-
77956791391
-
Exhaled nitric oxide in pulmonary diseases: a comprehensive review
-
Barnes PJ, et al. Exhaled nitric oxide in pulmonary diseases: a comprehensive review. Chest 2010;138:682-692.
-
(2010)
Chest
, vol.138
, pp. 682-692
-
-
Barnes, P.J.1
-
104
-
-
0033768818
-
Clinical aspects of exhaled nitric oxide
-
Kharitonov SA, Barnes PJ. Clinical aspects of exhaled nitric oxide. Eur Respir J 2000;16:781-792.
-
(2000)
Eur Respir J
, vol.16
, pp. 781-792
-
-
Kharitonov, S.A.1
Barnes, P.J.2
-
105
-
-
0031017415
-
Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticoids
-
Kharitonov SA, Rajakulasingam K, O'Connor BJ, Durham SR, Barnes PJ. Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticoids. J Allergy Clin Immunol 1997;99:58-64.
-
(1997)
J Allergy Clin Immunol
, vol.99
, pp. 58-64
-
-
Kharitonov, S.A.1
Rajakulasingam, K.2
O'Connor, B.J.3
Durham, S.R.4
Barnes, P.J.5
-
107
-
-
0038604348
-
A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics
-
Hansel TT, et al. A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics. FASEB J 2003;17:1298-1300.
-
(2003)
FASEB J
, vol.17
, pp. 1298-1300
-
-
Hansel, T.T.1
-
108
-
-
36249008584
-
Selective inducible nitric oxide synthase inhibition has no effect on allergen challenge in asthma
-
Singh D, et al. Selective inducible nitric oxide synthase inhibition has no effect on allergen challenge in asthma. Am J Respir Crit Care Med 2007;176:988-993.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 988-993
-
-
Singh, D.1
-
109
-
-
0028915226
-
High nitric oxide production in human paranasal sinuses
-
Lundberg JON, et al. High nitric oxide production in human paranasal sinuses. Nature Med 1995;1:370-373.
-
(1995)
Nature Med
, vol.1
, pp. 370-373
-
-
Lundberg, J.O.N.1
-
110
-
-
70349174810
-
Adenosine receptors as targets for therapeutic intervention in asthma and chronic obstructive pulmonary disease
-
Polosa R, Blackburn MR. Adenosine receptors as targets for therapeutic intervention in asthma and chronic obstructive pulmonary disease. Trends Pharmacol Sci 2009;30:528-535.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 528-535
-
-
Polosa, R.1
Blackburn, M.R.2
-
111
-
-
79953758259
-
A potential role for P2X7R in allergic airway inflammation in mice and humans
-
Muller T, et al. A potential role for P2X7R in allergic airway inflammation in mice and humans. Am J Respir Cell Mol Biol 2011;44:456-464.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, pp. 456-464
-
-
Muller, T.1
-
112
-
-
34547655975
-
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells
-
Idzko M, et al. Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat Med 2007;13:913-919.
-
(2007)
Nat Med
, vol.13
, pp. 913-919
-
-
Idzko, M.1
-
113
-
-
27144549227
-
Effects of aerosolized adenosine 5'-triphosphate vs adenosine 5'-monophosphate on dyspnea and airway caliber in healthy nonsmokers and patients with asthma
-
Basoglu OK, Pelleg A, Essilfie-Quaye S, Brindicci C, Barnes PJ, Kharitonov SA. Effects of aerosolized adenosine 5'-triphosphate vs adenosine 5'-monophosphate on dyspnea and airway caliber in healthy nonsmokers and patients with asthma. Chest 2005;128:1905-1909.
-
(2005)
Chest
, vol.128
, pp. 1905-1909
-
-
Basoglu, O.K.1
Pelleg, A.2
Essilfie-Quaye, S.3
Brindicci, C.4
Barnes, P.J.5
Kharitonov, S.A.6
-
114
-
-
77649179433
-
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
-
Tschopp J, Schroder K. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol 2010;10:210-215.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 210-215
-
-
Tschopp, J.1
Schroder, K.2
-
115
-
-
33645973265
-
Chronic effects of mechanical force on airways
-
Tschumperlin DJ, Drazen JM. Chronic effects of mechanical force on airways. Annu Rev Physiol 2006;68:563-583.
-
(2006)
Annu Rev Physiol
, vol.68
, pp. 563-583
-
-
Tschumperlin, D.J.1
Drazen, J.M.2
-
116
-
-
77951695782
-
Airway smooth muscle remodeling is a dynamic process in severe long-standing asthma
-
Hassan M, et al. Airway smooth muscle remodeling is a dynamic process in severe long-standing asthma. J Allergy Clin Immunol 2010;125:1037-1045.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1037-1045
-
-
Hassan, M.1
-
117
-
-
78650511132
-
Bronchial thermoplasty for severe asthma
-
Cox G. Bronchial thermoplasty for severe asthma. Curr Opin Pulm Med 2011;17:34-38.
-
(2011)
Curr Opin Pulm Med
, vol.17
, pp. 34-38
-
-
Cox, G.1
-
118
-
-
77949887505
-
Fibrogenic reactions in lung disease
-
Araya J, Nishimura SL. Fibrogenic reactions in lung disease. Annu Rev Pathol 2010;5:77-98.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 77-98
-
-
Araya, J.1
Nishimura, S.L.2
-
120
-
-
58149498454
-
Relationships between eosinophilic inflammation, tissue remodeling, and fibrosis in eosinophilic esophagitis
-
Aceves SS, Ackerman SJ. Relationships between eosinophilic inflammation, tissue remodeling, and fibrosis in eosinophilic esophagitis. Immunol Allergy Clin North Am 2009;29:197-xiv.
-
(2009)
Immunol Allergy Clin North Am
, vol.29
-
-
Aceves, S.S.1
Ackerman, S.J.2
-
121
-
-
66049084770
-
The airway vasculature: recent advances and clinical implications
-
Paredi P, Barnes PJ. The airway vasculature: recent advances and clinical implications. Thorax 2009;64:444-450.
-
(2009)
Thorax
, vol.64
, pp. 444-450
-
-
Paredi, P.1
Barnes, P.J.2
-
122
-
-
25444532515
-
Correlation of exhaled breath temperature with bronchial blood flow in asthma
-
Paredi P, Kharitonov SA, Barnes PJ. Correlation of exhaled breath temperature with bronchial blood flow in asthma. Respir Res 2005;6:15.
-
(2005)
Respir Res
, vol.6
, pp. 15
-
-
Paredi, P.1
Kharitonov, S.A.2
Barnes, P.J.3
-
123
-
-
34948842015
-
Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis
-
Siddiqui S, et al. Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis. J Allergy Clin Immunol 2007;120:813-819.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 813-819
-
-
Siddiqui, S.1
-
124
-
-
42649101652
-
Angiogenesis: a potentially critical part of remodelling in chronic airway diseases?
-
Walters EH, Reid D, Soltani A, Ward C. Angiogenesis: a potentially critical part of remodelling in chronic airway diseases? Pharmacol Ther 2008;118:128-137.
-
(2008)
Pharmacol Ther
, vol.118
, pp. 128-137
-
-
Walters, E.H.1
Reid, D.2
Soltani, A.3
Ward, C.4
-
125
-
-
78649735324
-
Airway mucus function and dysfunction
-
Fahy JV, Dickey BF. Airway mucus function and dysfunction. N Engl J Med 2010;363:2233-2247.
-
(2010)
N Engl J Med
, vol.363
, pp. 2233-2247
-
-
Fahy, J.V.1
Dickey, B.F.2
-
126
-
-
70349664159
-
SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production
-
Chen G, et al. SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production. J Clin Invest 2009;119:2914-2924.
-
(2009)
J Clin Invest
, vol.119
, pp. 2914-2924
-
-
Chen, G.1
-
127
-
-
54049094727
-
Coupling of airway ciliary activity and mucin secretion to mechanical stresses by purinergic signaling
-
Davis CW, Lazarowski E. Coupling of airway ciliary activity and mucin secretion to mechanical stresses by purinergic signaling. Respir Physiol Neurobiol 2008;163:208-213.
-
(2008)
Respir Physiol Neurobiol
, vol.163
, pp. 208-213
-
-
Davis, C.W.1
Lazarowski, E.2
-
128
-
-
8544250584
-
Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium
-
Burgel PR, Nadel JA. Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium. Thorax 2004;59:992-996.
-
(2004)
Thorax
, vol.59
, pp. 992-996
-
-
Burgel, P.R.1
Nadel, J.A.2
-
129
-
-
0037791697
-
The role of neural inflammation in asthma and chronic obstructive pulmonary disease
-
Joos GF, De Swert KO, Schelfhout V, Pauwels RA. The role of neural inflammation in asthma and chronic obstructive pulmonary disease. Ann NY Acad Sci 2003;992:218-230.
-
(2003)
Ann NY Acad Sci
, vol.992
, pp. 218-230
-
-
Joos, G.F.1
De Swert, K.O.2
Schelfhout, V.3
Pauwels, R.A.4
-
130
-
-
0035126782
-
Neurogenic inflammation in the airways
-
Barnes PJ. Neurogenic inflammation in the airways. Respir Physiol 2001;125:145-154.
-
(2001)
Respir Physiol
, vol.125
, pp. 145-154
-
-
Barnes, P.J.1
-
131
-
-
67049119907
-
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
-
Caceres AI, et al. A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci U S A 2009;106:9099-9104.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9099-9104
-
-
Caceres, A.I.1
-
132
-
-
52949104704
-
Neurogenic inflammation of the upper airway mucosa
-
Lacroix JS, Landis BN. Neurogenic inflammation of the upper airway mucosa. Rhinology 2008;46:163-165.
-
(2008)
Rhinology
, vol.46
, pp. 163-165
-
-
Lacroix, J.S.1
Landis, B.N.2
-
134
-
-
78650901948
-
Calcitonin gene-related peptide- and vascular endothelial growth factor-positive inflammatory cells in late-phase allergic skin reactions in atopic subjects
-
Kay AB. Calcitonin gene-related peptide- and vascular endothelial growth factor-positive inflammatory cells in late-phase allergic skin reactions in atopic subjects. J Allergy Clin Immunol 2011;127:232-237.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 232-237
-
-
Kay, A.B.1
-
135
-
-
36549024003
-
The nerve growth factor and its receptors in airway inflammatory diseases
-
Freund-Michel V, Frossard N. The nerve growth factor and its receptors in airway inflammatory diseases. Pharmacol Ther 2008;117:52-76.
-
(2008)
Pharmacol Ther
, vol.117
, pp. 52-76
-
-
Freund-Michel, V.1
Frossard, N.2
-
136
-
-
76149145360
-
The role of neurotrophins in the pathophysiology of allergic rhinitis
-
Raap U, Braunstahl GJ. The role of neurotrophins in the pathophysiology of allergic rhinitis. Curr Opin Allergy Clin Immunol 2010;10:8-13.
-
(2010)
Curr Opin Allergy Clin Immunol
, vol.10
, pp. 8-13
-
-
Raap, U.1
Braunstahl, G.J.2
-
137
-
-
76749112958
-
The skin neurotrophic network in health and disease
-
Borroni RG, Truzzi F, Pincelli C. The skin neurotrophic network in health and disease. Actas Dermosifiliogr 2009;100(Suppl.):70-74.
-
(2009)
Actas Dermosifiliogr
, vol.100
, Issue.SUPPL.
, pp. 70-74
-
-
Borroni, R.G.1
Truzzi, F.2
Pincelli, C.3
-
138
-
-
0035919584
-
Release of nerve growth factor by human pulmonary epithelial cells: role in airway inflammatory diseases
-
Fox AJ, Patel HJ, Barnes PJ, Belvisi MG. Release of nerve growth factor by human pulmonary epithelial cells: role in airway inflammatory diseases. Eur J Pharmacol 2001;424:159-162.
-
(2001)
Eur J Pharmacol
, vol.424
, pp. 159-162
-
-
Fox, A.J.1
Patel, H.J.2
Barnes, P.J.3
Belvisi, M.G.4
-
140
-
-
33644748288
-
TrkAd5: a novel therapeutic agent for treatment of inflammatory pain and asthma
-
Watson JJ, et al. TrkAd5: a novel therapeutic agent for treatment of inflammatory pain and asthma. J Pharmacol Exp Ther 2006;316:1122-1129.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 1122-1129
-
-
Watson, J.J.1
-
141
-
-
33748435749
-
Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA
-
de Vries A, et al. Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA. Clin Exp Allergy 2006;36:1192-1200.
-
(2006)
Clin Exp Allergy
, vol.36
, pp. 1192-1200
-
-
de Vries, A.1
-
142
-
-
0034846885
-
Local increase in the number of mast cells and expression of nerve growth factor in the bronchus of asthmatic patients after repeated inhalation of allergen at low-dose
-
Kassel O, et al. Local increase in the number of mast cells and expression of nerve growth factor in the bronchus of asthmatic patients after repeated inhalation of allergen at low-dose. Clin Exp Allergy 2001;31:1432-1440.
-
(2001)
Clin Exp Allergy
, vol.31
, pp. 1432-1440
-
-
Kassel, O.1
-
143
-
-
64249105703
-
The role of neuro-immune cross-talk in the regulation of inflammation and remodelling in asthma
-
Veres TZ, Rochlitzer S, Braun A. The role of neuro-immune cross-talk in the regulation of inflammation and remodelling in asthma. Pharmacol Ther 2009;122:203-214.
-
(2009)
Pharmacol Ther
, vol.122
, pp. 203-214
-
-
Veres, T.Z.1
Rochlitzer, S.2
Braun, A.3
-
146
-
-
77649270933
-
Social stress and asthma: the role of corticosteroid insensitivity
-
Haczku A, Panettieri RA Jr. Social stress and asthma: the role of corticosteroid insensitivity. J Allergy Clin Immunol 2010;125:550-558.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 550-558
-
-
Haczku, A.1
Panettieri Jr, R.A.2
-
147
-
-
67649213033
-
Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production
-
Bailey MT, et al. Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production. J Immunol 2009;182:7888-7896.
-
(2009)
J Immunol
, vol.182
, pp. 7888-7896
-
-
Bailey, M.T.1
-
148
-
-
67651108817
-
Stress and airway reactivity in a murine model of allergic airway inflammation
-
Quarcoo D, Pavlovic S, Joachim RA. Stress and airway reactivity in a murine model of allergic airway inflammation. Neuroimmunomodulation 2009;16:318-324.
-
(2009)
Neuroimmunomodulation
, vol.16
, pp. 318-324
-
-
Quarcoo, D.1
Pavlovic, S.2
Joachim, R.A.3
-
150
-
-
33747595955
-
Transcription factors in airway diseases
-
Barnes PJ. Transcription factors in airway diseases. Lab Invest 2006;86:867-872.
-
(2006)
Lab Invest
, vol.86
, pp. 867-872
-
-
Barnes, P.J.1
-
151
-
-
0030615201
-
Nuclear factor-kB: a pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M. Nuclear factor-kB: a pivotal transcription factor in chronic inflammatory diseases. New Engl J Med 1997;336:1066-1071.
-
(1997)
New Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
152
-
-
0031731150
-
Activation and localization of transcription factor, nuclear factor-kB, in asthma
-
Hart LA, Krishnan VL, Adcock IM, Barnes PJ, Chung KF. Activation and localization of transcription factor, nuclear factor-kB, in asthma. Am J Respir Crit Care Med 1998;158:1585-1592.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1585-1592
-
-
Hart, L.A.1
Krishnan, V.L.2
Adcock, I.M.3
Barnes, P.J.4
Chung, K.F.5
-
153
-
-
14744285888
-
Histone acetylation and deacetylation: importance in inflammatory lung diseases
-
Barnes PJ, Adcock IM, Ito K. Histone acetylation and deacetylation: importance in inflammatory lung diseases. Eur Respir J 2005;25:552-563.
-
(2005)
Eur Respir J
, vol.25
, pp. 552-563
-
-
Barnes, P.J.1
Adcock, I.M.2
Ito, K.3
-
155
-
-
33744477341
-
How corticosteroids control inflammation
-
Barnes PJ. How corticosteroids control inflammation. Br J Pharmacol 2006;148:245-254.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 245-254
-
-
Barnes, P.J.1
-
156
-
-
34249679048
-
GATA-3 - not just for Th2 cells anymore
-
Ho IC, Pai SY. GATA-3 - not just for Th2 cells anymore. Cell Mol Immunol 2007;4:15-29.
-
(2007)
Cell Mol Immunol
, vol.4
, pp. 15-29
-
-
Ho, I.C.1
Pai, S.Y.2
-
157
-
-
40049100163
-
Role of GATA-3 in allergic diseases
-
Barnes PJ. Role of GATA-3 in allergic diseases. Curr Mol Med 2008;8:330-334.
-
(2008)
Curr Mol Med
, vol.8
, pp. 330-334
-
-
Barnes, P.J.1
-
158
-
-
0034837698
-
Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies
-
Caramori G, et al. Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies. Eur Respir J 2001;18:466-473.
-
(2001)
Eur Respir J
, vol.18
, pp. 466-473
-
-
Caramori, G.1
-
159
-
-
0033049690
-
Gene expression of the GATA-3 transcription factor is increased in atopic asthma
-
Nakamura Y, et al. Gene expression of the GATA-3 transcription factor is increased in atopic asthma. J Allergy Clin Immunol 1999;103:215-222.
-
(1999)
J Allergy Clin Immunol
, vol.103
, pp. 215-222
-
-
Nakamura, Y.1
-
160
-
-
33846935457
-
Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3
-
Maneechotesuwan K, et al. Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3. J Immunol 2007;178:2491-2498.
-
(2007)
J Immunol
, vol.178
, pp. 2491-2498
-
-
Maneechotesuwan, K.1
-
161
-
-
0037059509
-
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
-
Finotto S, et al. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 2002;295:336-338.
-
(2002)
Science
, vol.295
, pp. 336-338
-
-
Finotto, S.1
-
162
-
-
12344269852
-
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
-
Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science 2005;307:430-433.
-
(2005)
Science
, vol.307
, pp. 430-433
-
-
Hwang, E.S.1
Szabo, S.J.2
Schwartzberg, P.L.3
Glimcher, L.H.4
-
163
-
-
38149045608
-
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation
-
Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi K. IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation. J Immunol 2007;179:4415-4423.
-
(2007)
J Immunol
, vol.179
, pp. 4415-4423
-
-
Yoshimoto, T.1
Yoshimoto, T.2
Yasuda, K.3
Mizuguchi, J.4
Nakanishi, K.5
-
164
-
-
33645065358
-
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
-
Usui T, et al. T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J Exp Med 2006;203:755-766.
-
(2006)
J Exp Med
, vol.203
, pp. 755-766
-
-
Usui, T.1
-
165
-
-
0036305450
-
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
Avni O, Lee D, Macian F, Szabo SJ, Glimcher LH, Rao A. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol 2002;3:643-651.
-
(2002)
Nat Immunol
, vol.3
, pp. 643-651
-
-
Avni, O.1
Lee, D.2
Macian, F.3
Szabo, S.J.4
Glimcher, L.H.5
Rao, A.6
-
166
-
-
66349134442
-
Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease
-
Maneechotesuwan K, et al. Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease. PLoS Med 2009;6:e1000076.
-
(2009)
PLoS Med
, vol.6
-
-
Maneechotesuwan, K.1
-
167
-
-
78149326083
-
A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma
-
Wang YH, et al. A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J Exp Med 2010;207:2479-2491.
-
(2010)
J Exp Med
, vol.207
, pp. 2479-2491
-
-
Wang, Y.H.1
-
168
-
-
0036100050
-
JAK-STAT signaling in asthma
-
Pernis AB, Rothman PB. JAK-STAT signaling in asthma. J Clin Invest 2002;109:1279-1283.
-
(2002)
J Clin Invest
, vol.109
, pp. 1279-1283
-
-
Pernis, A.B.1
Rothman, P.B.2
-
170
-
-
78649710769
-
Mast cell homeostasis and the JAK-STAT pathway
-
Morales JK, Falanga YT, Depcrynski A, Fernando J, Ryan JJ. Mast cell homeostasis and the JAK-STAT pathway. Genes Immun 2010;11:599-608.
-
(2010)
Genes Immun
, vol.11
, pp. 599-608
-
-
Morales, J.K.1
Falanga, Y.T.2
Depcrynski, A.3
Fernando, J.4
Ryan, J.J.5
-
171
-
-
77749343026
-
Signal transduction by the atopy-associated human thymic stromal lymphopoietin (TSLP) receptor depends on Janus kinase function
-
Wohlmann A, Sebastian K, Borowski A, Krause S, Friedrich K. Signal transduction by the atopy-associated human thymic stromal lymphopoietin (TSLP) receptor depends on Janus kinase function. Biol Chem 2010;391:181-186.
-
(2010)
Biol Chem
, vol.391
, pp. 181-186
-
-
Wohlmann, A.1
Sebastian, K.2
Borowski, A.3
Krause, S.4
Friedrich, K.5
-
172
-
-
33847335909
-
Suppressor of cytokine signaling in allergic inflammation
-
Knisz J, Rothman PB. Suppressor of cytokine signaling in allergic inflammation. J Allergy Clin Immunol 2007;119:739-745.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 739-745
-
-
Knisz, J.1
Rothman, P.B.2
-
173
-
-
77955480504
-
Epigenetics and environmental lung disease
-
Schwartz DA. Epigenetics and environmental lung disease. Proc Am Thorac Soc 2010;7:123-125.
-
(2010)
Proc Am Thorac Soc
, vol.7
, pp. 123-125
-
-
Schwartz, D.A.1
-
174
-
-
33646196946
-
Regulation of Th2 differentiation and Il4 locus accessibility
-
Ansel KM, Djuretic I, Tanasa B, Rao A. Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol 2006;24:607-656.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 607-656
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
175
-
-
59849085588
-
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation
-
Lal G, et al. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol 2009;182:259-273.
-
(2009)
J Immunol
, vol.182
, pp. 259-273
-
-
Lal, G.1
-
176
-
-
55849150592
-
In utero supplementation with methyl donors enhances allergic airway disease in mice
-
Hollingsworth JW, et al. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest 2008;118:3462-3469.
-
(2008)
J Clin Invest
, vol.118
, pp. 3462-3469
-
-
Hollingsworth, J.W.1
-
177
-
-
0033821409
-
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits IL-1b-induced histone H4 acetylation on lysines 8 and 12
-
Ito K, Barnes PJ, Adcock IM. Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits IL-1b-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol 2000;20:6891-6903.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6891-6903
-
-
Ito, K.1
Barnes, P.J.2
Adcock, I.M.3
-
178
-
-
0036683630
-
Expression and activity of histone deacetylases (HDACs) in human asthmatic airways
-
Ito K, et al. Expression and activity of histone deacetylases (HDACs) in human asthmatic airways. Am J Respir Crit Care Med 2002;166:392-396.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 392-396
-
-
Ito, K.1
-
179
-
-
3142676314
-
Histone acetylase and deacetylase activity in alveolar macrophages and blood monocytes in asthma
-
Cosio BG, et al. Histone acetylase and deacetylase activity in alveolar macrophages and blood monocytes in asthma. Am J Respir Crit Care Med 2004;170:141-147.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 141-147
-
-
Cosio, B.G.1
-
180
-
-
33745746529
-
Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma
-
Hew M, et al. Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma. Am J Respir Crit Care Med 2006;174:134-141.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 134-141
-
-
Hew, M.1
-
181
-
-
70549095099
-
Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease
-
Mattes J, Collison A, Plank M, Phipps S, Foster PS. Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease. Proc Natl Acad Sci U S A 2009;106:18704-18709.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18704-18709
-
-
Mattes, J.1
Collison, A.2
Plank, M.3
Phipps, S.4
Foster, P.S.5
-
182
-
-
0026784117
-
Endogenous cortisol regulates immunoglobulin E-dependent late phase reactions
-
Herrscher RF, Kasper C, Sullivan TJ. Endogenous cortisol regulates immunoglobulin E-dependent late phase reactions. J Clin Invest 1992;90:593-603.
-
(1992)
J Clin Invest
, vol.90
, pp. 593-603
-
-
Herrscher, R.F.1
Kasper, C.2
Sullivan, T.J.3
-
183
-
-
0036529090
-
Clinical relevance of airway 11beta-hydroxysteroid dehydrogenase type II enzyme in asthma
-
Orsida BE, Krozowski ZS, Walters EH. Clinical relevance of airway 11beta-hydroxysteroid dehydrogenase type II enzyme in asthma. Am J Respir Crit Care Med 2002;165:1010-1014.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1010-1014
-
-
Orsida, B.E.1
Krozowski, Z.S.2
Walters, E.H.3
-
184
-
-
0031718925
-
Inhibitory cytokines in asthma
-
Barnes PJ, Lim S. Inhibitory cytokines in asthma. Mol Medicine Today 1998;4:452-458.
-
(1998)
Mol Medicine Today
, vol.4
, pp. 452-458
-
-
Barnes, P.J.1
Lim, S.2
-
185
-
-
33748879109
-
Adenovirus expressing interleukin-1 receptor antagonist alleviates allergic airway inflammation in a murine model of asthma
-
Wang CC, et al. Adenovirus expressing interleukin-1 receptor antagonist alleviates allergic airway inflammation in a murine model of asthma. Gene Ther 2006;13:1414-1421.
-
(2006)
Gene Ther
, vol.13
, pp. 1414-1421
-
-
Wang, C.C.1
-
186
-
-
0029966181
-
Expression of interleukin-1 beta (IL-1b) and interleukin-1 receptor antagonist (IL-1ra) on asthmatic bronchial epithelium
-
Sousa AR, Lane SJ, Nakhosteen JA, Lee TH, Poston RN. Expression of interleukin-1 beta (IL-1b) and interleukin-1 receptor antagonist (IL-1ra) on asthmatic bronchial epithelium. Am J Respir Crit Care Med 1996;154:1061-1066.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 1061-1066
-
-
Sousa, A.R.1
Lane, S.J.2
Nakhosteen, J.A.3
Lee, T.H.4
Poston, R.N.5
-
187
-
-
0035141618
-
IL-12/IL-13 axis in allergic asthma
-
Wills-Karp M. IL-12/IL-13 axis in allergic asthma. J Allergy Clin Immunol 2001;107:9-18.
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 9-18
-
-
Wills-Karp, M.1
-
188
-
-
6644223789
-
Effects of recombinant human interleukin-12 on eosinophils, airway hyperreactivity and the late asthmatic response
-
Bryan S, et al. Effects of recombinant human interleukin-12 on eosinophils, airway hyperreactivity and the late asthmatic response. Lancet 2000;356:2149-2153.
-
(2000)
Lancet
, vol.356
, pp. 2149-2153
-
-
Bryan, S.1
-
189
-
-
0030934422
-
Expression of IL-12 and IL-13 mRNA in asthma and their modulation in reponse to steroids
-
Naseer T, et al. Expression of IL-12 and IL-13 mRNA in asthma and their modulation in reponse to steroids. Am J Resp Crit Care Med 1997;155:845-851.
-
(1997)
Am J Resp Crit Care Med
, vol.155
, pp. 845-851
-
-
Naseer, T.1
-
190
-
-
23444462668
-
A role for IL-27 in early regulation of Th1 differentiation
-
Owaki T, et al. A role for IL-27 in early regulation of Th1 differentiation. J Immunol 2005;175:2191-2200.
-
(2005)
J Immunol
, vol.175
, pp. 2191-2200
-
-
Owaki, T.1
-
191
-
-
0031172369
-
IL-10: a potential therapy for allergic inflammation?
-
Pretolani M, Goldman M. IL-10: a potential therapy for allergic inflammation? Immunol Today 1997;18:277-280.
-
(1997)
Immunol Today
, vol.18
, pp. 277-280
-
-
Pretolani, M.1
Goldman, M.2
-
192
-
-
0031943945
-
Inhaled corticosteroids increase IL-10 but reduce MIP-1a, GM-CSF and IFN-g release from alveolar macrophages in asthma
-
John M, et al. Inhaled corticosteroids increase IL-10 but reduce MIP-1a, GM-CSF and IFN-g release from alveolar macrophages in asthma. Am J Respir Crit Care Med 1998;157:256-262.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 256-262
-
-
John, M.1
-
193
-
-
28544433747
-
Regulatory T cells and IL-10 in allergic inflammation
-
Hawrylowicz CM. Regulatory T cells and IL-10 in allergic inflammation. J Exp Med 2005;202:1459-1463.
-
(2005)
J Exp Med
, vol.202
, pp. 1459-1463
-
-
Hawrylowicz, C.M.1
-
194
-
-
34548237449
-
Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation
-
Bohle B, Kinaciyan T, Gerstmayr M, Radakovics A, Jahn-Schmid B, Ebner C. Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation. J Allergy Clin Immunol 2007;120:707-713.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 707-713
-
-
Bohle, B.1
Kinaciyan, T.2
Gerstmayr, M.3
Radakovics, A.4
Jahn-Schmid, B.5
Ebner, C.6
-
195
-
-
42749087384
-
The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29
-
Commins S, Steinke JW, Borish L. The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29. J Allergy Clin Immunol 2008;121:1108-1111.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 1108-1111
-
-
Commins, S.1
Steinke, J.W.2
Borish, L.3
-
196
-
-
0028911427
-
Bronchoprotective role for endogenous prostaglandin E2
-
Pavord ID, Tattersfield AE. Bronchoprotective role for endogenous prostaglandin E2. Lancet 1995;344:436-438.
-
(1995)
Lancet
, vol.344
, pp. 436-438
-
-
Pavord, I.D.1
Tattersfield, A.E.2
-
198
-
-
51849153327
-
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma
-
Planaguma A, et al. Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma. Am J Respir Crit Care Med 2008;178:574-582.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 574-582
-
-
Planaguma, A.1
-
199
-
-
47849086917
-
Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation
-
Haworth O, Cernadas M, Yang R, Serhan CN, Levy BD. Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation. Nat Immunol 2008;9:873-879.
-
(2008)
Nat Immunol
, vol.9
, pp. 873-879
-
-
Haworth, O.1
Cernadas, M.2
Yang, R.3
Serhan, C.N.4
Levy, B.D.5
-
200
-
-
79251592284
-
Protective effect of resolvin E1 on the development of asthmatic airway inflammation
-
Aoki H, et al. Protective effect of resolvin E1 on the development of asthmatic airway inflammation. Biochem Biophys Res Commun 2010;400:128-133.
-
(2010)
Biochem Biophys Res Commun
, vol.400
, pp. 128-133
-
-
Aoki, H.1
-
201
-
-
33846001661
-
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness
-
Levy BD, et al. Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. J Immunol 2007;178:496-502.
-
(2007)
J Immunol
, vol.178
, pp. 496-502
-
-
Levy, B.D.1
-
202
-
-
33645336289
-
Indoleamine-2,3-dioxygenase modulation of allergic immune responses
-
Le AV, Broide DH. Indoleamine-2, 3-dioxygenase modulation of allergic immune responses. Curr Allergy Asthma Rep 2006;6:27-31.
-
(2006)
Curr Allergy Asthma Rep
, vol.6
, pp. 27-31
-
-
Le, A.V.1
Broide, D.H.2
-
203
-
-
38149085198
-
Sputum indoleamine-2, 3-dioxygenase activity is increased in asthmatic airways by using inhaled corticosteroids
-
Maneechotesuwan K, Supawita S, Kasetsinsombat K, Wongkajornsilp A, Barnes PJ. Sputum indoleamine-2, 3-dioxygenase activity is increased in asthmatic airways by using inhaled corticosteroids. J Allergy Clin Immunol 2008;121:43-50.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 43-50
-
-
Maneechotesuwan, K.1
Supawita, S.2
Kasetsinsombat, K.3
Wongkajornsilp, A.4
Barnes, P.J.5
-
204
-
-
58149193237
-
Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma
-
Maneechotesuwan K, et al. Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. J Allergy Clin Immunol 2009;123:239-248.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 239-248
-
-
Maneechotesuwan, K.1
-
205
-
-
77957788255
-
Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase
-
Maneechotesuwan K, Ekjiratrakul W, Kasetsinsombat K, Wongkajornsilp A, Barnes PJ. Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase. J Allergy Clin Immunol 2010;126:754-762.
-
(2010)
J Allergy Clin Immunol
, vol.126
, pp. 754-762
-
-
Maneechotesuwan, K.1
Ekjiratrakul, W.2
Kasetsinsombat, K.3
Wongkajornsilp, A.4
Barnes, P.J.5
-
206
-
-
77954033984
-
New drugs for asthma: is there any progress?
-
Barnes PJ. New drugs for asthma: is there any progress? Trends Pharmacol Sci 2010;31:335-343.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 335-343
-
-
Barnes, P.J.1
-
207
-
-
74849106935
-
Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease
-
Barnes PJ. Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2009;6:693-696.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 693-696
-
-
Barnes, P.J.1
-
208
-
-
65249157050
-
Epigenetics, DNA methylation, and chromatin modifying drugs
-
Szyf M. Epigenetics, DNA methylation, and chromatin modifying drugs. Annu Rev Pharmacol Toxicol 2009;49:243-263.
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 243-263
-
-
Szyf, M.1
|