메뉴 건너뛰기




Volumn 39, Issue 8, 2009, Pages 1145-1151

Intrinsic asthma: Not so different from allergic asthma but driven by superantigens?

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CHEMOKINE RECEPTOR ANTAGONIST; CORTICOSTEROID; CYCLOSPORIN; CYTOKERATIN 18; IMMUNOGLOBULIN; IMMUNOGLOBULIN E; OMALIZUMAB; PHOSPHOTRANSFERASE INHIBITOR; STAPHYLOCOCCUS ENTEROTOXIN; SUPERANTIGEN; TACROLIMUS;

EID: 67650418178     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2009.03298.x     Document Type: Review
Times cited : (103)

References (54)
  • 2
    • 33845987340 scopus 로고    scopus 로고
    • Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program
    • Moore WC, Bleecker ER, Curran-Everett D et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol 2007 119 : 405 13.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 405-13
    • Moore, W.C.1    Bleecker, E.R.2    Curran-Everett, D.3
  • 5
    • 0024491638 scopus 로고
    • Association of asthma with serum IgE levels and skin-test reactivity to allergens
    • Burrows B, Martinez FD, Halonen M, Barbee RA, Cline MG. Association of asthma with serum IgE levels and skin-test reactivity to allergens. New Engl J Med 1989 320 : 271 7.
    • (1989) New Engl J Med , vol.320 , pp. 271-7
    • Burrows, B.1    Martinez, F.D.2    Halonen, M.3    Barbee, R.A.4    Cline, M.G.5
  • 6
    • 0033772971 scopus 로고    scopus 로고
    • Elevation of total serum immunoglobulin e is associated with asthma in nonallergic individuals
    • Beeh KM, Ksoll M, Buhl R. Elevation of total serum immunoglobulin E is associated with asthma in nonallergic individuals. Eur Respir J 2000 16 : 609 14.
    • (2000) Eur Respir J , vol.16 , pp. 609-14
    • Beeh, K.M.1    Ksoll, M.2    Buhl, R.3
  • 7
    • 0024564434 scopus 로고
    • Trichophyton asthma: Sensitization of bronchi and upper airways to a dermatophyte antigen
    • Ward GW, Karlsson G, Rose G, Platts-Mills TAE. Trichophyton asthma: sensitization of bronchi and upper airways to a dermatophyte antigen. Lancet 1989 1 : 859 62.
    • (1989) Lancet , vol.1 , pp. 859-62
    • Ward, G.W.1    Karlsson, G.2    Rose, G.3    Platts-Mills, T.A.E.4
  • 8
    • 0042530486 scopus 로고    scopus 로고
    • Allergic and nonallergic forms of atopic diseases
    • Novak N, Bieber T. Allergic and nonallergic forms of atopic diseases. J Allergy Clin Immunol 2003 112 : 252 62.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 252-62
    • Novak, N.1    Bieber, T.2
  • 10
    • 34248539919 scopus 로고    scopus 로고
    • Aspirin-sensitive rhinosinusitis and asthma
    • Kowalski ML. Aspirin-sensitive rhinosinusitis and asthma. Clin Allergy Immunol 2007 19 : 147 75.
    • (2007) Clin Allergy Immunol , vol.19 , pp. 147-75
    • Kowalski, M.L.1
  • 11
    • 0032725001 scopus 로고    scopus 로고
    • The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: More similarities than differences
    • Humbert M, Menz G, Ying S et al. The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences. Immunol Today 1999 20 : 528 33.
    • (1999) Immunol Today , vol.20 , pp. 528-33
    • Humbert, M.1    Menz, G.2    Ying, S.3
  • 12
    • 40049104892 scopus 로고    scopus 로고
    • Immunology of asthma and chronic obstructive pulmonary disease
    • Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Immunol Rev 2008 8 : 183 92.
    • (2008) Nat Immunol Rev , vol.8 , pp. 183-92
    • Barnes, P.J.1
  • 13
    • 0033485409 scopus 로고    scopus 로고
    • Eosinophil chemotactic chemokines [eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4], and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (intrinsic) asthmatics
    • Ying S, Meng Q, Zeibecoglou K et al. Eosinophil chemotactic chemokines [eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4], and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (intrinsic) asthmatics. J Immunol 1999 163 : 6321 9.
    • (1999) J Immunol , vol.163 , pp. 6321-9
    • Ying, S.1    Meng, Q.2    Zeibecoglou, K.3
  • 14
    • 0034744486 scopus 로고    scopus 로고
    • TH2 cytokine-associated transcription factors in atopic and nonatopic asthma: Evidence for differential signal transducer and activator of transcription 6 expression
    • Christodoulopoulos P, Cameron L, Nakamura Y et al. TH2 cytokine-associated transcription factors in atopic and nonatopic asthma: evidence for differential signal transducer and activator of transcription 6 expression. J Allergy Clin Immunol 2001 107 : 586 91.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 586-91
    • Christodoulopoulos, P.1    Cameron, L.2    Nakamura, Y.3
  • 15
    • 0033794334 scopus 로고    scopus 로고
    • Macrophage subpopulations and macrophage-derived cytokines in sputum of atopic and nonatopic asthmatic subjects and atopic and normal control subjects
    • Zeibecoglou K, Ying S, Meng Q, Poulter LW, Robinson DS, Kay AB. Macrophage subpopulations and macrophage-derived cytokines in sputum of atopic and nonatopic asthmatic subjects and atopic and normal control subjects. J Allergy Clin Immunol 2000 106 : 697 704. (Pubitemid 30799724)
    • (2000) Journal of Allergy and Clinical Immunology , vol.106 , Issue.4 , pp. 697-704
    • Zeibecoglou, K.1    Ying, S.2    Meng, Q.3    Poulter, L.W.4    Robinson, D.S.5    Kay, A.B.6
  • 16
    • 0034744489 scopus 로고    scopus 로고
    • Local expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma
    • Ying S, Humbert M, Meng Q et al. Local expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma. J Allergy Clin Immunol 2001 107 : 686 92.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 686-92
    • Ying, S.1    Humbert, M.2    Meng, Q.3
  • 17
    • 33845952641 scopus 로고    scopus 로고
    • Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma
    • Takhar P, Corrigan CJ, Smurthwaite L et al. Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma. J Allergy Clin Immunol 2007 119 : 213 8.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 213-8
    • Takhar, P.1    Corrigan, C.J.2    Smurthwaite, L.3
  • 18
    • 0029889058 scopus 로고    scopus 로고
    • High affinity IgE receptor (FCεRI)-bearing cells in bronchial biopsies from atopic and non-atopic asthma
    • Humbert M, Grant JA, Tabora-Barata L et al. High affinity IgE receptor (FCεRI)-bearing cells in bronchial biopsies from atopic and non-atopic asthma. Am J Respsir Crit Care Med 1996 153 : 1931 7.
    • (1996) Am J Respsir Crit Care Med , vol.153 , pp. 1931-7
    • Humbert, M.1    Grant, J.A.2    Tabora-Barata, L.3
  • 20
    • 33750031785 scopus 로고    scopus 로고
    • Asthma exacerbations. 3: Pathogenesis
    • Wark PA, Gibson PG. Asthma exacerbations. 3: pathogenesis. Thorax 2006 61 : 909 15.
    • (2006) Thorax , vol.61 , pp. 909-15
    • Wark, P.A.1    Gibson, P.G.2
  • 21
    • 29744465421 scopus 로고    scopus 로고
    • Chlamydophila pneumoniae and Mycoplasma pneumoniae: A role in asthma pathogenesis?
    • Johnston SL, Martin RJ. Chlamydophila pneumoniae and Mycoplasma pneumoniae: a role in asthma pathogenesis? Am J Respir Crit Care Med 2005 172 : 1078 89.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 1078-89
    • Johnston, S.L.1    Martin, R.J.2
  • 22
    • 0029789306 scopus 로고    scopus 로고
    • Isotype-specific antibody responses to acute Mycoplasma pneumoniae infection
    • Seggev JS, Sedmak GV, Kurup VP. Isotype-specific antibody responses to acute Mycoplasma pneumoniae infection. Ann Allergy Asthma Immunol 1996 77 : 67 73. (Pubitemid 26264977)
    • (1996) Annals of Allergy, Asthma and Immunology , vol.77 , Issue.1 , pp. 67-73
    • Seggev, J.S.1    Sedmak, G.V.2    Kurup, V.P.3
  • 23
    • 0035286568 scopus 로고    scopus 로고
    • Levels of interleukin-2, interferon-gamma, and interleukin-4 in bronchoalveolar lavage fluid from patients with Mycoplasma pneumonia: Implication of tendency toward increased immunoglobulin e production
    • Koh YY, Park Y, Lee HJ, Kim CK. Levels of interleukin-2, interferon-gamma, and interleukin-4 in bronchoalveolar lavage fluid from patients with Mycoplasma pneumonia: implication of tendency toward increased immunoglobulin E production. Pediatrics 2001 107 : E39.
    • (2001) Pediatrics , vol.107 , pp. 39
    • Koh, Y.Y.1    Park, Y.2    Lee, H.J.3    Kim, C.K.4
  • 28
    • 33750369712 scopus 로고    scopus 로고
    • Role of staphylococcal superantigen-specific IgE antibodies in aspirin-intolerant asthma
    • Lee JY, Kim HM, Ye YM et al. Role of staphylococcal superantigen-specific IgE antibodies in aspirin-intolerant asthma. Allergy Asthma Proc 2006 27 : 341 6.
    • (2006) Allergy Asthma Proc , vol.27 , pp. 341-6
    • Lee, J.Y.1    Kim, H.M.2    Ye, Y.M.3
  • 29
    • 53649083007 scopus 로고    scopus 로고
    • Human mast cell activation by Staphylococcus aureus: Interleukin-8 and tumor necrosis factor alpha release and the role of Toll-like receptor 2 and CD48 molecules
    • Rocha-de-Souza CM, Berent-Maoz B, Mankuta D, Moses AE, Levi-Schaffer F. Human mast cell activation by Staphylococcus aureus: interleukin-8 and tumor necrosis factor alpha release and the role of Toll-like receptor 2 and CD48 molecules. Infect Immun 2008 76 : 4489 97.
    • (2008) Infect Immun , vol.76 , pp. 4489-97
    • Rocha-De-Souza, C.M.1    Berent-Maoz, B.2    Mankuta, D.3    Moses, A.E.4    Levi-Schaffer, F.5
  • 30
    • 52049123299 scopus 로고    scopus 로고
    • The bacterial superantigen and superantigen-like proteins
    • Fraser JD, Proft T. The bacterial superantigen and superantigen-like proteins. Immunol Rev 2008 225 : 226 43.
    • (2008) Immunol Rev , vol.225 , pp. 226-43
    • Fraser, J.D.1    Proft, T.2
  • 31
    • 0345222473 scopus 로고    scopus 로고
    • Airway exposure to bacterial superantigen (SEB) induces lymphocyte-dependent airway inflammation associated with increased airway responsiveness - A model for non-allergic asthma
    • Herz U, Ruckert R, Wollenhaupt K et al. Airway exposure to bacterial superantigen (SEB) induces lymphocyte-dependent airway inflammation associated with increased airway responsiveness - a model for non-allergic asthma. Eur J Immunol 1999 29 : 1021 31.
    • (1999) Eur J Immunol , vol.29 , pp. 1021-31
    • Herz, U.1    Ruckert, R.2    Wollenhaupt, K.3
  • 32
    • 24944571691 scopus 로고    scopus 로고
    • Superantigens and chronic rhinosinusitis: Detection of staphylococcal exotoxins in nasal polyps
    • Seiberling KA, Conley DB, Tripathi A et al. Superantigens and chronic rhinosinusitis: detection of staphylococcal exotoxins in nasal polyps. Laryngoscope 2005 115 : 1580 5.
    • (2005) Laryngoscope , vol.115 , pp. 1580-5
    • Seiberling, K.A.1    Conley, D.B.2    Tripathi, A.3
  • 33
    • 51549095640 scopus 로고    scopus 로고
    • Inhalation of Staphylococcus aureus enterotoxin A induces IFN-gamma and CD8 T cell-dependent airway and interstitial lung pathology in mice
    • Muralimohan G, Rossi RJ, Guernsey LA, Thrall RS, Vella AT. Inhalation of Staphylococcus aureus enterotoxin A induces IFN-gamma and CD8 T cell-dependent airway and interstitial lung pathology in mice. J Immunol 2008 181 : 3698 705.
    • (2008) J Immunol , vol.181 , pp. 3698-705
    • Muralimohan, G.1    Rossi, R.J.2    Guernsey, L.A.3    Thrall, R.S.4    Vella, A.T.5
  • 35
    • 0033407143 scopus 로고    scopus 로고
    • Analysis of immunoglobulin e VH transcripts in a bronchial biopsy of an asthmatic patient confirms bias towards VH5, and indicates local clonal expansion, somatic mutation and isotype switch events
    • Snow RE, Djukanovic R, Stevenson FK. Analysis of immunoglobulin E VH transcripts in a bronchial biopsy of an asthmatic patient confirms bias towards VH5, and indicates local clonal expansion, somatic mutation and isotype switch events. Immunology 1999 98 : 646 51.
    • (1999) Immunology , vol.98 , pp. 646-51
    • Snow, R.E.1    Djukanovic, R.2    Stevenson, F.K.3
  • 36
    • 23244457657 scopus 로고    scopus 로고
    • Biased use of VH5 IgE-positive B cells in the nasal mucosa in allergic rhinitis
    • Coker HA, Harries HE, Banfield GK et al. Biased use of VH5 IgE-positive B cells in the nasal mucosa in allergic rhinitis. J Allergy Clin Immunol 2005 116 : 445 52.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 445-52
    • Coker, H.A.1    Harries, H.E.2    Banfield, G.K.3
  • 37
    • 0034020396 scopus 로고    scopus 로고
    • Clonal expansion of T cells infiltrating in the airways of non-atopic asthmatics
    • Umibe T, Kita Y, Nakao A et al. Clonal expansion of T cells infiltrating in the airways of non-atopic asthmatics. Clin Exp Immunol 2000 119 : 390 7.
    • (2000) Clin Exp Immunol , vol.119 , pp. 390-7
    • Umibe, T.1    Kita, Y.2    Nakao, A.3
  • 38
    • 1942531991 scopus 로고    scopus 로고
    • T regulatory cells in atopic dermatitis and subversion of their activity by superantigens
    • Ou LS, Goleva E, Hall C, Leung DY. T regulatory cells in atopic dermatitis and subversion of their activity by superantigens. J Allergy Clin Immunol 2004 113 : 756 63.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 756-63
    • Ou, L.S.1    Goleva, E.2    Hall, C.3    Leung, D.Y.4
  • 39
    • 33644777428 scopus 로고    scopus 로고
    • Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes
    • Cardona ID, Goleva E, Ou LS, Leung DY. Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes. J Allergy Clin Immunol 2006 117 : 688 95.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 688-95
    • Cardona, I.D.1    Goleva, E.2    Ou, L.S.3    Leung, D.Y.4
  • 40
    • 7944220552 scopus 로고    scopus 로고
    • Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway
    • Li LB, Goleva E, Hall CF, Ou LS, Leung DY. Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway. J Allergy Clin Immunol 2004 114 : 1059 69.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1059-69
    • Li, L.B.1    Goleva, E.2    Hall, C.F.3    Ou, L.S.4    Leung, D.Y.5
  • 41
    • 38449105934 scopus 로고    scopus 로고
    • Cutting edge: TCR revision affects predominantly Foxp3 cells and skews them toward the Th17 lineage
    • Zehn D, Bevan MJ, Fink PJ. Cutting edge: TCR revision affects predominantly Foxp3 cells and skews them toward the Th17 lineage. J Immunol 2007 179 : 5653 7.
    • (2007) J Immunol , vol.179 , pp. 5653-7
    • Zehn, D.1    Bevan, M.J.2    Fink, P.J.3
  • 42
    • 58149131262 scopus 로고    scopus 로고
    • IL-17 in atopic eczema: Linking allergen-specific adaptive and microbial-triggered innate immune response
    • Eyerich K, Pennino D, Scarponi C et al. IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J Allergy Clin Immunol 2009 123 : 59 66.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 59-66
    • Eyerich, K.1    Pennino, D.2    Scarponi, C.3
  • 45
    • 0036606245 scopus 로고    scopus 로고
    • Identification of cytokeratin 18 as a bronchial epithelial autoantigen associated with nonallergic asthma
    • Nahm DH, Lee YE, Yim EJ et al. Identification of cytokeratin 18 as a bronchial epithelial autoantigen associated with nonallergic asthma. Am J Respir Crit Care Med 2002 165 : 1536 9.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1536-9
    • Nahm, D.H.1    Lee, Y.E.2    Yim, E.J.3
  • 47
    • 67651251805 scopus 로고    scopus 로고
    • Increased IgG antibody-induced cytotoxicity against airway epithelial cells in patients with nonallergic asthma
    • in press).
    • Kwon B, Lee HA, Choi GS, Ye YM, Nahm DH, Park HS. Increased IgG antibody-induced cytotoxicity against airway epithelial cells in patients with nonallergic asthma. J Clin Immunol 2009 (in press).
    • (2009) J Clin Immunol
    • Kwon, B.1    Lee, H.A.2    Choi, G.S.3    Ye, Y.M.4    Nahm, D.H.5    Park, H.S.6
  • 48
    • 39049170984 scopus 로고    scopus 로고
    • Global strategy for asthma management and prevention: GINA executive summary
    • Bateman ED, Hurd SS, Barnes PJ et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008 31 : 143 78.
    • (2008) Eur Respir J , vol.31 , pp. 143-78
    • Bateman, E.D.1    Hurd, S.S.2    Barnes, P.J.3
  • 50
    • 33846644267 scopus 로고    scopus 로고
    • Does anti-IgE therapy help in asthma? Efficacy and controversies
    • DOI 10.1146/annurev.med.58.061705.145252
    • Avila PC. Does anti-IgE therapy help in asthma? Efficacy and controversies. Annu Rev Med 2007 58 : 185 203. (Pubitemid 46706509)
    • (2007) Annual Review of Medicine , vol.58 , pp. 185-203
    • Avila, P.C.1
  • 51
    • 37349132468 scopus 로고    scopus 로고
    • Neutralization of staphylococcal exotoxins in vitro by human-origin intravenous immunoglobulin
    • Yanagisawa C, Hanaki H, Natae T, Sunakawa K. Neutralization of staphylococcal exotoxins in vitro by human-origin intravenous immunoglobulin. J Infect Chemother 2007 13 : 368 72.
    • (2007) J Infect Chemother , vol.13 , pp. 368-72
    • Yanagisawa, C.1    Hanaki, H.2    Natae, T.3    Sunakawa, K.4
  • 52
    • 0036358435 scopus 로고    scopus 로고
    • Intravenous gamma-globulin therapy in bronchial asthma
    • Schwartz HJ, Berger M. Intravenous gamma-globulin therapy in bronchial asthma. Allergy Asthma Proc 2002 23 : 15 8.
    • (2002) Allergy Asthma Proc , vol.23 , pp. 15-8
    • Schwartz, H.J.1    Berger, M.2
  • 53
    • 0037501014 scopus 로고    scopus 로고
    • Cyclosporin as an oral corticosteroid sparing agent in stable asthma (Cochrane Review)
    • CD002993.
    • Evans DJ, Cullinan P, Geddes DM. Cyclosporin as an oral corticosteroid sparing agent in stable asthma (Cochrane Review). Cochrane Database Syst Rev 2001 2 CD002993.
    • (2001) Cochrane Database Syst Rev , vol.2
    • Evans, D.J.1    Cullinan, P.2    Geddes, D.M.3
  • 54
    • 52049113214 scopus 로고    scopus 로고
    • New targets for drug development in asthma
    • Adcock IM, Caramori G, Chung KF. New targets for drug development in asthma. Lancet 2008 372 : 1073 87.
    • (2008) Lancet , vol.372 , pp. 1073-87
    • Adcock, I.M.1    Caramori, G.2    Chung, K.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.