메뉴 건너뛰기




Volumn 57, Issue 4, 2008, Pages 307-312

Role of prostaglandin D2 and its receptors in the pathophysiology of asthma

Author keywords

Asthma; CRTH2; DP; Eosinophils; Lipid mediators; Single nucleotide polymorphisms

Indexed keywords

CHEMOTTRACTANT RECEPTOR HOMOLOGOUS MOLECULE EXPRESSED ON TH2 PROTEIN; D PROSTANOID RECEPTOR; G PROTEIN COUPLED RECEPTOR; PROSTAGLANDIN D; PROSTAGLANDIN D2; PROSTAGLANDIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 59549107791     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.08-RAI-0033     Document Type: Review
Times cited : (49)

References (49)
  • 1
    • 0025348647 scopus 로고
    • 2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma
    • 2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma. Am Rev Respir Dis 1990;142:126-32.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 126-132
    • Liu, M.C.1    Bleecker, E.R.2    Lichtenstein, L.M.3
  • 2
    • 0026518532 scopus 로고
    • Mediator concentrations in bronchoalveolar lavage fluid of patients with mild asymptomatic bronchial asthma
    • Crea AE, Nakhosteen JA, Lee TH. Mediator concentrations in bronchoalveolar lavage fluid of patients with mild asymptomatic bronchial asthma. Eur Respir J 1992;5:190-5.
    • (1992) Eur Respir J , vol.5 , pp. 190-195
    • Crea, A.E.1    Nakhosteen, J.A.2    Lee, T.H.3
  • 3
    • 0025837891 scopus 로고
    • Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes
    • Liu MC, Hubbard WC, Proud D et al. Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes. Am Rev Respir Dis 1991;144:51-8.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 51-58
    • Liu, M.C.1    Hubbard, W.C.2    Proud, D.3
  • 5
  • 7
    • 0025909039 scopus 로고
    • 2 in the long-lasting airways vasodilatation induced by allergen in the sensitized pig
    • 2 in the long-lasting airways vasodilatation induced by allergen in the sensitized pig. Acta Physiol Scand 1991; 143:93-103.
    • (1991) Acta Physiol Scand , vol.143 , pp. 93-103
    • Alving, K.1    Matran, R.2    Lundberg, J.M.3
  • 9
    • 0019419071 scopus 로고
    • Effects of arachidonic acid, monohydroxyeicosatetraenoic acid and prostaglandins on the release of mucous glycoproteins from human airways in vitro
    • Marom Z, Shelhamer JH, Kaliner M. Effects of arachidonic acid, monohydroxyeicosatetraenoic acid and prostaglandins on the release of mucous glycoproteins from human airways in vitro. J Clin Invest 1981;67:1695-702.
    • (1981) J Clin Invest , vol.67 , pp. 1695-1702
    • Marom, Z.1    Shelhamer, J.H.2    Kaliner, M.3
  • 10
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: Advances in eicosanoid biology
    • Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 2001;294:1871-75.
    • (2001) Science , vol.294 , pp. 1871-1875
    • Funk, C.D.1
  • 12
    • 0027974137 scopus 로고
    • Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene
    • Hirata M, Kakizuka A, Aizawa M, Ushikubi F, Narumiya S. Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene. Proc Natl Acad Sci USA 1994; 91:11192-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11192-11196
    • Hirata, M.1    Kakizuka, A.2    Aizawa, M.3    Ushikubi, F.4    Narumiya, S.5
  • 13
    • 0029134144 scopus 로고
    • Molecular cloning and characterization of the human prostanoid DP receptor
    • Boie Y, Sawyer N, Slipetz DM, Metters KM, Abramovitz M. Molecular cloning and characterization of the human prostanoid DP receptor. J Biol Chem 1995;270:18910-6.
    • (1995) J Biol Chem , vol.270 , pp. 18910-18916
    • Boie, Y.1    Sawyer, N.2    Slipetz, D.M.3    Metters, K.M.4    Abramovitz, M.5
  • 14
    • 0035862329 scopus 로고    scopus 로고
    • 2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2
    • 2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. J Exp Med 2001;193:255-61.
    • (2001) J Exp Med , vol.193 , pp. 255-261
    • Hirai, H.1    Tanaka, K.2    Yoshie, O.3
  • 15
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
    • Hata AN, Breyer RM. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol Ther 2004;103:147-66.
    • (2004) Pharmacol Ther , vol.103 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 17
    • 0037988825 scopus 로고    scopus 로고
    • 2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. J Immunol 2003; 170:4943-52.
    • 2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. J Immunol 2003; 170:4943-52.
  • 18
    • 38049163745 scopus 로고    scopus 로고
    • 2 suppresses human NK cell function via signaling through D prostanoid receptor
    • 2 suppresses human NK cell function via signaling through D prostanoid receptor. J Immunol 2007;179: 2766-73.
    • (2007) J Immunol , vol.179 , pp. 2766-2773
    • Chen, Y.1    Perussia, B.2    Campbell, K.S.3
  • 19
    • 4143121034 scopus 로고    scopus 로고
    • 2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2
    • 2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2. Clin Exp Allergy 2004; 34:1283-90.
    • (2004) Clin Exp Allergy , vol.34 , pp. 1283-1290
    • Yoshimura-Uchiyama, C.1    Iikura, M.2    Yamaguchi, M.3
  • 20
    • 27744514582 scopus 로고    scopus 로고
    • 2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells
    • 2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells. J Immunol 2005;175:6531-6.
    • (2005) J Immunol , vol.175 , pp. 6531-6536
    • Xue, L.1    Gyles, S.L.2    Wettey, F.R.3
  • 21
    • 0035883174 scopus 로고    scopus 로고
    • 2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor
    • 2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor. Blood 2001; 98:1942-8.
    • (2001) Blood , vol.98 , pp. 1942-1948
    • Monneret, G.1    Gravel, S.2    Diamond, M.3    Rokach, J.4    Powell, W.S.5
  • 24
    • 27144494922 scopus 로고    scopus 로고
    • 2 prime eotaxin-induced chemotaxis on human eosinophils through peroxisome proliferator-activated receptor-γ ligation
    • 2 prime eotaxin-induced chemotaxis on human eosinophils through peroxisome proliferator-activated receptor-γ ligation. J Immunol 2005; 175:5744-50.
    • (2005) J Immunol , vol.175 , pp. 5744-5750
    • Kobayashi, Y.1    Ueki, S.2    Mahemuti, G.3
  • 25
    • 0036468739 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression during allergic inflammation in guinea-pig lungs
    • Oguma T, Asano K, Shiomi T et al. Cyclooxygenase-2 expression during allergic inflammation in guinea-pig lungs. Am J Respir Crit Care Med 2002;165:382-6.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 382-386
    • Oguma, T.1    Asano, K.2    Shiomi, T.3
  • 26
    • 0041920928 scopus 로고    scopus 로고
    • 2 reinforces Th2 type inflammatory responses of airways to low-dose antigen through bronchial expression of macrophage-derived chemokine
    • 2 reinforces Th2 type inflammatory responses of airways to low-dose antigen through bronchial expression of macrophage-derived chemokine. J Exp Med 2003;198: 533-43.
    • (2003) J Exp Med , vol.198 , pp. 533-543
    • Honda, K.1    Arima, M.2    Cheng, G.3
  • 27
    • 0036135587 scopus 로고    scopus 로고
    • Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice
    • Fujitani Y, Kanaoka Y, Aritake K, Uodome N, Okazaki-Hatake K, Urade Y. Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice. J Immunol 2002;168:443-9.
    • (2002) J Immunol , vol.168 , pp. 443-449
    • Fujitani, Y.1    Kanaoka, Y.2    Aritake, K.3    Uodome, N.4    Okazaki-Hatake, K.5    Urade, Y.6
  • 29
    • 0034922462 scopus 로고    scopus 로고
    • Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751
    • Arimura A, Yasui K, Kishino J et al. Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751. J Pharmacol Exp Therapeut 2001;298:411-9.
    • (2001) J Pharmacol Exp Therapeut , vol.298 , pp. 411-419
    • Arimura, A.1    Yasui, K.2    Kishino, J.3
  • 30
    • 49749119253 scopus 로고    scopus 로고
    • 2 receptor, DP, in eosinophil trafficking. J Immunol 2007;179:4792-9.
    • 2 receptor, DP, in eosinophil trafficking. J Immunol 2007;179:4792-9.
  • 31
    • 33847143728 scopus 로고    scopus 로고
    • Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells
    • Hammad H, Kool M, Soullie T et al. Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J Exp Med 2007; 204:357-67.
    • (2007) J Exp Med , vol.204 , pp. 357-367
    • Hammad, H.1    Kool, M.2    Soullie, T.3
  • 32
  • 33
    • 40449106779 scopus 로고    scopus 로고
    • 2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation
    • 2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation. J Immunol 2008;180:541-9.
    • (2008) J Immunol , vol.180 , pp. 541-549
    • Shiraishi, Y.1    Asano, K.2    Niimi, K.3
  • 34
    • 14844346424 scopus 로고    scopus 로고
    • 2 receptor DP2/CRTH2 increases allergic inflammation in mouse
    • 2 receptor DP2/CRTH2 increases allergic inflammation in mouse. J Immunol 2005;174:3703-8.
    • (2005) J Immunol , vol.174 , pp. 3703-3708
    • Spik, I.1    Brenuchon, C.2    Angeli, V.3
  • 37
    • 69249240524 scopus 로고    scopus 로고
    • 2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation
    • 2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation. Respir Res 2007; 8:16.
    • (2007) Respir Res , vol.8 , pp. 16
    • Uller, L.1    Mathiesen, J.M.2    Alenmyr, L.3
  • 38
    • 23444435395 scopus 로고    scopus 로고
    • Cutting edge: Chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment
    • Chevalier E, Stock J, Fisher T et al. Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment. J Immunol 2005;175: 2056-60.
    • (2005) J Immunol , vol.175 , pp. 2056-2060
    • Chevalier, E.1    Stock, J.2    Fisher, T.3
  • 39
    • 0033521870 scopus 로고    scopus 로고
    • Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family
    • Abe H, Takeshita T, Nagata K et al. Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family. Gene 1999; 227:71-7.
    • (1999) Gene , vol.227 , pp. 71-77
    • Abe, H.1    Takeshita, T.2    Nagata, K.3
  • 40
    • 0036118620 scopus 로고    scopus 로고
    • New polymorphisms of haematopoietic prostaglandin D synthase and human prostanoid DP receptor genes
    • Noguchi E, Shibasaki M, Kamioka M et al. New polymorphisms of haematopoietic prostaglandin D synthase and human prostanoid DP receptor genes. Clin Exp Allergy 2002;32:93-6.
    • (2002) Clin Exp Allergy , vol.32 , pp. 93-96
    • Noguchi, E.1    Shibasaki, M.2    Kamioka, M.3
  • 41
    • 16044372682 scopus 로고    scopus 로고
    • A genome-wide search for quantitative trait loci underlying asthma
    • Daniels SE, Bhattacharrya S, James A et al. A genome-wide search for quantitative trait loci underlying asthma. Nature 1996; 383: 247-250.
    • (1996) Nature , vol.383 , pp. 247-250
    • Daniels, S.E.1    Bhattacharrya, S.2    James, A.3
  • 42
    • 0035030475 scopus 로고    scopus 로고
    • Chromosome 14 linkage analysis and mutation study of 2 serpin genes in allergic asthmatic families
    • Malerba G, Patuzzo C, Trabetti E et al. Chromosome 14 linkage analysis and mutation study of 2 serpin genes in allergic asthmatic families. J Allergy Clin Immunol 2001; 107:654-8.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 654-658
    • Malerba, G.1    Patuzzo, C.2    Trabetti, E.3
  • 44
    • 33745271811 scopus 로고    scopus 로고
    • Promoter genetic variants of prostanoid DP receptor (PTGDR) gene in patients with asthma
    • Sanz C, Isidoro-Garcia M, Davila I et al. Promoter genetic variants of prostanoid DP receptor (PTGDR) gene in patients with asthma. Allergy 2006;61:543-8.
    • (2006) Allergy , vol.61 , pp. 543-548
    • Sanz, C.1    Isidoro-Garcia, M.2    Davila, I.3
  • 45
    • 34547416977 scopus 로고    scopus 로고
    • Association of PTGDR gene polymorphisms with asthma in two Caucasian populations
    • Zhu G, Vestbo J, Lenney W et al. Association of PTGDR gene polymorphisms with asthma in two Caucasian populations. Genes Immun 2007;8:398-403.
    • (2007) Genes Immun , vol.8 , pp. 398-403
    • Zhu, G.1    Vestbo, J.2    Lenney, W.3
  • 46
    • 34548525071 scopus 로고    scopus 로고
    • Lack of association between three promoter polymorphisms of PTGDR gene and asthma in a Chinese Han population
    • Li J, Liu Q, Wang P et al. Lack of association between three promoter polymorphisms of PTGDR gene and asthma in a Chinese Han population. Int J Immunogenet 2007;34:353-7.
    • (2007) Int J Immunogenet , vol.34 , pp. 353-357
    • Li, J.1    Liu, Q.2    Wang, P.3
  • 47
    • 33845208949 scopus 로고    scopus 로고
    • The PTGDR gene is not associated with asthma in 3 ethnically diverse populations
    • Tsai YJ, Choudhry S, Kho J et al. The PTGDR gene is not associated with asthma in 3 ethnically diverse populations. J Allergy Clin Immunol 2006;118:1242-8.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 1242-1248
    • Tsai, Y.J.1    Choudhry, S.2    Kho, J.3
  • 48
    • 8444225971 scopus 로고    scopus 로고
    • Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability
    • Huang JL, Gao PS, Mathias RA et al. Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability. Hum Mol Genet 2004;13:2691-7.
    • (2004) Hum Mol Genet , vol.13 , pp. 2691-2697
    • Huang, J.L.1    Gao, P.S.2    Mathias, R.A.3
  • 49
    • 33845952601 scopus 로고    scopus 로고
    • Genetic impact of functional single nucleotide polymorphisms in the 3′-UTR region of the chemoattractant receptor expressed on Th2 cells(CRTH2)gene on asthma and atopy in a Japanese population
    • Maeda Y, Hizawa N, Takahashi D, Fukui Y, Konno S, Nishimura M. Genetic impact of functional single nucleotide polymorphisms in the 3′-UTR region of the chemoattractant receptor expressed on Th2 cells(CRTH2)gene on asthma and atopy in a Japanese population. Int Archiv Allergy Immunol 2007;142:51-8.
    • (2007) Int Archiv Allergy Immunol , vol.142 , pp. 51-58
    • Maeda, Y.1    Hizawa, N.2    Takahashi, D.3    Fukui, Y.4    Konno, S.5    Nishimura, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.