Mepolizumab and exacerbations of refractory eosinophilic asthma

New England Journal of Medicine

Volumn 360, Issue 10, 2009, Pages 973-984

  Haldar, Pranabashis ^a   Brightling, Christopher E ^a   Hargadon, Beverley ^a   Gupta, Sumit ^a   Monteiro, William ^a   Sousa, Ana ^b   Marshall, Richard P ^b   Bradding, Peter ^a   Green, Ruth H ^a   WardIaw, Andrew J ^a   Pavord, Ian D ^a,c  

^a UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c GLENFIELD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE DIPROPIONATE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; MEPOLIZUMAB; METHOTREXATE; MONTELUKAST; PLACEBO; PREDNISOLONE; SALBUTAMOL; BIOLOGICAL MARKER; INTERLEUKIN 5; MONOCLONAL ANTIBODY;

ABDOMINAL PAIN; ADULT; AGED; AGEUSIA; ARTICLE; ASTHMA; BLOOD ANALYSIS; BRONCHUS HYPERREACTIVITY; CLINICAL FEATURE; CLINICAL TRIAL; CONJUNCTIVAL HEMORRHAGE; CONJUNCTIVITIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISEASE EXACERBATION; DISEASE SEVERITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG WITHDRAWAL; EJACULATION DISORDER; EOSINOPHIL COUNT; EOSINOPHILIA; ERECTILE DYSFUNCTION; FATIGUE; FEMALE; FLUSHING; FORCED EXPIRATORY VOLUME; GOUT; HAND PARESTHESIA; HERPES ZOSTER; HOSPITALIZATION; HUMAN; HUMAN TISSUE; INTRAOCULAR HEMORRHAGE; MACULOPAPULAR RASH; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MUSCULOSKELETAL PAIN; NIGHT SWEAT; NOSE ULCER; PRIORITY JOURNAL; PRURITUS; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RASH; RECURRENT DISEASE; REFRACTORY EOSINOPHILIC ASTHMA; RESPIRATORY TRACT INFLAMMATION; SIDE EFFECT; SPUTUM ANALYSIS; SUBCONJUNCTIVAL HEMORRHAGE; SYNCOPE; THORAX PAIN; TREATMENT DURATION; TREATMENT OUTCOME; UPPER RESPIRATORY TRACT INFECTION; WOUND HEALING IMPAIRMENT; BLOOD; DRUG ANTAGONISM; DRUG COMBINATION; DRUG EFFECT; EOSINOPHIL; IMMUNOLOGY; LEUKOCYTE COUNT; MIDDLE AGED; PATHOPHYSIOLOGY; SPUTUM; STATISTICS;

ADULT; AGED; ANTIBODIES, MONOCLONAL; ASTHMA; BIOLOGICAL MARKERS; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; EOSINOPHILIA; EOSINOPHILS; FEMALE; FORCED EXPIRATORY VOLUME; HOSPITALIZATION; HUMANS; INTERLEUKIN-5; LEUKOCYTE COUNT; MALE; MIDDLE AGED; PREDNISOLONE; QUALITY OF LIFE; RECURRENCE; SPUTUM; TREATMENT OUTCOME; YOUNG ADULT;

EID: 61849086181     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa0808991     Document Type: Article

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