-
1
-
-
0037072064
-
Alzheimer's disease
-
DOI 10.1016/S0140-6736(02)09420-5
-
Burns A, Byrne EJ, Maurer K. Alzheimer's disease. Lancet 2002;360:163-5. (Pubitemid 34786210)
-
(2002)
Lancet
, vol.360
, Issue.9327
, pp. 163-165
-
-
Burns, A.1
Byrne, E.J.2
Maurer, K.3
-
2
-
-
29144508843
-
Alzheimer's disease I. Global prevalence of dementia: A delphi consensus study
-
Ferri CP, Prince M, Brayne C, Brodaty H, Fratiglioni L, Ganguli M, Hall K, Hasegawa K, Hendrie H, Huang Y, Jorm A, Mathers C, Menezes PR, Rimmer E, Scazufca M. Alzheimer's disease I. Global prevalence of dementia: a delphi consensus study. Lancet 2005;366:2112-7.
-
(2005)
Lancet
, vol.366
, pp. 2112-2117
-
-
Ferri, C.P.1
Prince, M.2
Brayne, C.3
Brodaty, H.4
Fratiglioni, L.5
Ganguli, M.6
Hall, K.7
Hasegawa, K.8
Hendrie, H.9
Huang, Y.10
Jorm, A.11
Mathers, C.12
Menezes, P.R.13
Rimmer, E.14
Scazufca, M.15
-
3
-
-
34249697099
-
Forecasting the global burden of Alzheimer's disease
-
DOI 10.1016/j.jalz.2007.04.381, PII S155252600700475X
-
Brookmeyer R, Johnson E, Ziegler-Graham K, Arrighi HM. Forecasting the global burden of alzheimer's disease. Alzheimer's Dement 2007;3:186-91. (Pubitemid 46825511)
-
(2007)
Alzheimer's and Dementia
, vol.3
, Issue.3
, pp. 186-191
-
-
Brookmeyer, R.1
Johnson, E.2
Ziegler-Graham, K.3
Arrighi, H.M.4
-
5
-
-
0021909265
-
Cortical atrophy in senile dementia of the Alzheimer type is mainly due to a decrease in cortical length
-
DOI 10.1007/BF00698298
-
Duyckaerts C, Hauw JJ, Piette F, Rainsard C, Poulain V, Berthaux P, Escourolle R. Cortical atrophy in senile dementia of the alzheimer type is mainly due to a decrease in cortical length. Acta Neuropathol (Berl) 1985;66:72-4. (Pubitemid 15138012)
-
(1985)
Acta Neuropathologica
, vol.66
, Issue.1
, pp. 72-74
-
-
Duyckaerts, C.1
Hauw, J.J.2
Piette, F.3
-
6
-
-
36148973896
-
Automated cortical thickness measurements from MRI can accurately separate Alzheimer's patients from normal elderly controls
-
DOI 10.1016/j.neurobiolaging.2006.09.013, PII S0197458006003435
-
Lerch JP, Pruessner J, Zijdenbos AP, Collins DL, Teipel SJ, Hampel H, Evans AC. Automated cortical thickness measurements from mri can accurately separate alzheimer's patients from normal elderly controls. Neurobiol Aging 2008;29:23-30. (Pubitemid 350110605)
-
(2008)
Neurobiology of Aging
, vol.29
, Issue.1
, pp. 23-30
-
-
Lerch, J.P.1
Pruessner, J.2
Zijdenbos, A.P.3
Collins, D.L.4
Teipel, S.J.5
Hampel, H.6
Evans, A.C.7
-
7
-
-
0019494341
-
Some morphometric aspects of the brain in senile dementia of the Alzheimer type
-
DOI 10.1002/ana.410100209
-
Terry RD, Peck A, Deteresa R, Schechter R, Horoupian DS. Some morphometric aspects of the brain in senile dementia of the alzheimer type. Ann Neurol 1981;10:184-92. (Pubitemid 11053105)
-
(1981)
Annals of Neurology
, vol.10
, Issue.2
, pp. 184-192
-
-
Terry, R.D.1
Peck, A.2
DeTeresa, R.3
-
8
-
-
0030294729
-
Neurofibrillary pathology - Correlation with hippocampal formation atrophy in Alzheimer disease
-
DOI 10.1016/S0197-4580(96)00160-1, PII S0197458096001601
-
Bobinski M, Wegiel J, Wisniewski HM, Tarnawski M, Reisberg B, DeLeon MJ, Miller DC. Neurofibrillary pathology - correlation with hippocampal formation atrophy in alzheimer disease. Neurobiol Aging 1996;17:909-19. (Pubitemid 27022745)
-
(1996)
Neurobiology of Aging
, vol.17
, Issue.6
, pp. 909-919
-
-
Bobinski, M.1
Wegiel, J.2
Wisniewski, H.M.3
Tarnawski, M.4
Bobinski, M.5
Reisberg, B.6
De Leon, M.J.7
Miller, D.C.8
-
9
-
-
0342980328
-
In vivo pet imaging and postmortem studies suggest potentially reversible and irreversible stages of brain metabolic failure in alzheimer's disease
-
Rapoport SI. In vivo pet imaging and postmortem studies suggest potentially reversible and irreversible stages of brain metabolic failure in alzheimer's disease. Eur Arch Psychiatry Clin Neurosci 1999;249:46-55.
-
(1999)
Eur Arch Psychiatry Clin Neurosci
, vol.249
, pp. 46-55
-
-
Rapoport, S.I.1
-
10
-
-
0025987048
-
Physical basis of cognitive alterations in alzheimers-disease - Synapse loss is the major correlate of cognitive impairment
-
Terry RD, Masliah E, Salmon DP, Butters N, Deteresa R, Hill R, Hansen LA, Katzman R. Physical basis of cognitive alterations in alzheimers-disease - synapse loss is the major correlate of cognitive impairment. Ann Neurol 1991;30:572-80.
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
Deteresa, R.5
Hill, R.6
Hansen, L.A.7
Katzman, R.8
-
11
-
-
0035830408
-
Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease
-
Masliah E, Mallory M, Alford M, DeTeresa R, Hansen LA, McKeel DW, Morris JC. Altered expression of synaptic proteins occurs early during progression of alzheimer's disease. Neurology 2001;56:127-9. (Pubitemid 32059669)
-
(2001)
Neurology
, vol.56
, Issue.1
, pp. 127-129
-
-
Masliah, E.1
Mallory, M.2
Alford, M.3
DeTeresa, R.4
Hansen, L.A.5
McKeel Jr., D.W.6
Morris, J.C.7
-
12
-
-
0028235419
-
Synaptic and neuritic alterations during the progression of Alzheimer's disease
-
DOI 10.1016/0304-3940(94)90121-X
-
Masliah E, Mallory M, Hansen L, Richard D, Alford M, Terry R. Synaptic and neuritic alterations during the progression of alzheimer's disease. Neurosci Lett 1994;174:67-72. (Pubitemid 24205235)
-
(1994)
Neuroscience Letters
, vol.174
, Issue.1
, pp. 67-72
-
-
Masliah, E.1
Mallory, M.2
Hansen, L.3
DeTeresa, R.4
Alford, M.5
Terry, R.6
-
13
-
-
0025863618
-
Neuropathological staging of alzheimer-related changes
-
Berl
-
Braak H, Braak E. Neuropathological staging of alzheimer-related changes. Acta Neuropathol (Berl) 1991;82:239-59.
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
14
-
-
0347755563
-
Contribution of cerebral amyloid angiopathy to Alzheimer's disease
-
Love S. Contribution of cerebral amyloid angiopathy to alzheimer's disease. J Neurol Neurosurg Psychiatry 2004;75:1-4. (Pubitemid 38091257)
-
(2004)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.75
, Issue.1
, pp. 1-4
-
-
Love, S.1
-
15
-
-
34247611095
-
Fibrillar and oligomeric β-amyloid as distinct local biomarkers for Alzheimer's disease
-
DOI 10.1196/annals.1379.023, Imaging and the Aging Brain
-
Montalto MC, Farrar G, Hehir CT. Fibrillar and oligomeric β-amyloid as distinct local biomarkers for alzheimer's disease. Ann N Y Acad Sci 2007;1097:239-58. (Pubitemid 47084898)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1097
, pp. 239-258
-
-
Montalto, M.C.1
Farrar, G.2
Hehir, C.T.3
-
16
-
-
0023762975
-
Clinico-pathologic studies in dementia: Nondemented subjects with pathologically confirmed Alzheimer's disease
-
Crystal H, Dickson D, Fuld P, Masur D, Scott R, Mehler M, Masdeu J, Kawas C, Aronson M, Wolfson L. Clinicopathologic studies in dementia - nondemented subjects with pathologically confirmed alzheimers-disease. Neurology 1988;38:1682-7. (Pubitemid 18265029)
-
(1988)
Neurology
, vol.38
, Issue.11
, pp. 1682-1687
-
-
Crystal, H.1
Dickson, D.2
Fuld, P.3
Masur, D.4
Scott, R.5
Mehler, M.6
Masdeu, J.7
Kawas, C.8
Aronson, M.9
Wolfson, L.10
-
17
-
-
33344463679
-
Common mechanisms of amyloid oligomer pathogenesis in degenerative disease
-
DOI 10.1016/j.neurobiolaging.2005.04.017, PII S0197458005002344, Protein Misfolding in Alzheimer's and Other Age-Related Neurodegenerative Diseases
-
Glabe CG. Common mechanisms of amyloid oligomer pathogenesis in degenerative disease. Neurobiol Aging 2006;27:570-5. (Pubitemid 43290525)
-
(2006)
Neurobiology of Aging
, vol.27
, Issue.4
, pp. 570-575
-
-
Glabe, C.G.1
-
18
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
-
DOI 10.1074/jbc.M201750200
-
Dahlgren KN, Manelli AM, Stine WB, Baker LK, Krafft GA, LaDu MJ. Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability. J Biol Chem 2002;277:32046-53. (Pubitemid 34969015)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.35
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Blaine Jr., S.W.3
Baker, L.K.4
Krafft, G.A.5
Ladu, M.J.6
-
19
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
Lesne S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, Gallagher M, Ashe KH. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 2006;440:352-7.
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesne, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
Gallagher, M.7
Ashe, K.H.8
-
20
-
-
33645505550
-
Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: A potent role for trimers
-
Townsend M, Shankar GM, Mehta T, Walsh DM, Selkoe DJ. Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers. J Physiol-Lond 2006;572:477-92.
-
(2006)
J Physiol-Lond
, vol.572
, pp. 477-492
-
-
Townsend, M.1
Shankar, G.M.2
Mehta, T.3
Walsh, D.M.4
Selkoe, D.J.5
-
21
-
-
49149124343
-
Amyloid-β protein dimers isolated directly from alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, Li SM, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ. Amyloid-β protein dimers isolated directly from alzheimer's brains impair synaptic plasticity and memory. Nat Med 2008;14:837-42.
-
(2008)
Nat Med
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.M.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
-
22
-
-
57649171529
-
Characterisation of two antibodies to oligomeric aβ and their use in elisas on human brain tissue homogenates
-
van Helmond Z, Heesom K, Love S. Characterisation of two antibodies to oligomeric aβ and their use in elisas on human brain tissue homogenates. J Neurosci Methods 2009;176:206-12.
-
(2009)
J Neurosci Methods
, vol.176
, pp. 206-212
-
-
Van Helmond, Z.1
Heesom, K.2
Love, S.3
-
23
-
-
0032888131
-
Soluble amyloid β peptide concentration as a predictor of synaptic change in Alzheimer's disease
-
Lue LF, Kuo YM, Roher AE, Brachova L, Shen Y, Sue L, Beach T, Kurth JH, Rydel RE, Rogers J. Soluble amyloid-β peptide concentration as a predictor of synaptic change in alzheimer's disease. Am J Pathol 1999;155:853-62. (Pubitemid 29426831)
-
(1999)
American Journal of Pathology
, vol.155
, Issue.3
, pp. 853-862
-
-
Lue, L.-F.1
Kuo, Y.-M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
Beach, T.7
Kurth, J.H.8
Rydel, R.E.9
Rogers, J.10
-
24
-
-
0029671451
-
Water-soluble aβ (n-40, n-42) oligomers in normal and alzheimer disease brains
-
Kuo YM, Emmerling MR, VigoPelfrey C, Kasunic TC, Kirkpatrick JB, Murdoch GH, Ball MJ, Roher AE. Water-soluble aβ (n-40, n-42) oligomers in normal and alzheimer disease brains. J Biol Chem 1996;271:4077-81.
-
(1996)
J Biol Chem
, vol.271
, pp. 4077-4081
-
-
Kuo, Y.M.1
Emmerling, M.R.2
VigoPelfrey, C.3
Kasunic, T.C.4
Kirkpatrick, J.B.5
Murdoch, G.H.6
Ball, M.J.7
Roher, A.E.8
-
25
-
-
0032837741
-
The levels of soluble versus insoluble brain aβ distinguish Alzheimer's disease from normal and pathologic aging
-
DOI 10.1006/exnr.1999.7085
-
Wang J, Dickson DW, Trojanowski JQ, Lee VMY. The levels of soluble versus insoluble brain aβ distinguish alzheimer's disease from normal and pathologic aging. Exp Neurol 1999;158:328-37. (Pubitemid 29382824)
-
(1999)
Experimental Neurology
, vol.158
, Issue.2
, pp. 328-337
-
-
Wang, J.1
Dickson, D.W.2
Trojanowski, J.Q.3
Lee, V.M.-Y.4
-
26
-
-
0032590054
-
Soluble pool of aβ amyloid as a determinant of severity of neurodegeneration in alzheimer's disease
-
McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, Bush AI, Masters CL. Soluble pool of aβ amyloid as a determinant of severity of neurodegeneration in alzheimer's disease. Ann Neurol 1999;46:860-6.
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
27
-
-
0042838303
-
Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss
-
DOI 10.1073/pnas.1834302100
-
Gong YS, Chang L, Viola KL, Lacor PN, Lambert MP, Finch CE, Krafft GA, Klein WL. Alzheimer's disease-affected brain: presence of oligomeric aβ ligands (addls) suggests amolecular basis for reversible memory loss. Proc Natl Acad Sci U S A 2003;100:10417-22. (Pubitemid 37071893)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.18
, pp. 10417-10422
-
-
Gong, Y.1
Chang, L.2
Viola, K.L.3
Lacor, P.N.4
Lambert, M.P.5
Finch, C.E.6
Krafft, G.A.7
Klein, W.L.8
-
28
-
-
26644445247
-
B-amyloid is different in normal aging and in Alzheimer disease
-
DOI 10.1074/jbc.M501694200
-
Piccini A, Russo C, Gliozzi A, Relini A, Vitali A, Borghi R, Giliberto L, Armirotti A, D'Arrigo C, Bachi A, Cattaneo A, Canale C, Torrassa S, Saido TC, Markesbery W, Gambetti P, Tabaton M. B-amyloid is different in normal aging and in alzheimer disease. J Biol Chem 2005;280:34186-92. (Pubitemid 41443143)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.40
, pp. 34186-34192
-
-
Piccini, A.1
Russo, C.2
Gliozzi, A.3
Relini, A.4
Vitali, A.5
Borghi, R.6
Giliberto, L.7
Armirotti, A.8
D'Arrigo, C.9
Bachi, A.10
Cattaneo, A.11
Canale, C.12
Torrassa, S.13
Saido, T.C.14
Markesbery, W.15
Gambetti, P.16
Tabaton, M.17
-
29
-
-
33746809372
-
Physiological roles for amyloid beta peptides
-
Pearson HA, Peers C. Physiological roles for amyloid beta peptides. J Physiol-Lond 2006;575:5-10.
-
(2006)
J Physiol-Lond
, vol.575
, pp. 5-10
-
-
Pearson, H.A.1
Peers, C.2
-
30
-
-
13944276825
-
Twenty years of the alzheimer's disease amyloid hypothesis: A genetic perspective
-
Tanzi RE, Bertram L. Twenty years of the alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 2005;120:545-55.
-
(2005)
Cell
, vol.120
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
31
-
-
12144286502
-
Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients
-
DOI 10.1073/pnas.0205689101
-
Li R, Lindholm K, Yang LB, Yue X, Citron M, Yao RQ, Beach T, Sue L, Sabbagh M, Cai HB, Wong P, Price D, Shen Y. Amyloid β peptide load is correlated with increased β-secretase activity in sporadic alzheimer's disease patients. Proc Natl Acad Sci U S A 2004;101:3632-7. (Pubitemid 38338246)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.10
, pp. 3632-3637
-
-
Li, R.1
Lindholm, K.2
Yang, L.-B.3
Yue, X.4
Citron, M.5
Yan, R.6
Beach, T.7
Sue, L.8
Sebbagh, M.9
Cai, H.10
Wong, P.11
Price, D.12
Shen, Y.13
-
32
-
-
0037236622
-
Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer disease [1]
-
DOI 10.1038/nm0103-3
-
Yang LB, Lindholm K, Yan RQ, Citron M, Xia WM, Yang XL, Beach T, Sue L, Wong P, Price D, Li R, Shen Y. Elevated β-secretase expression and enzymatic activity detected in sporadic alzheimer disease. Nat Med 2003;9:3-4. (Pubitemid 36098241)
-
(2003)
Nature Medicine
, vol.9
, Issue.1
, pp. 3-4
-
-
Yang, L.-B.1
Lindholm, K.2
Yan, R.3
Citron, M.4
Xia, W.5
Yang, X.-L.6
Beach, T.7
Sue, L.8
Wong, P.9
Price, D.10
Li, R.11
Shen, Y.12
-
33
-
-
0036434569
-
A- and β-secretase: Profound changes in Alzheimer's disease
-
DOI 10.1016/S0006-291X(02)02635-9, PII S0006291X02026359
-
Tyler SJ, Dawbarn D, Wilcock GK, Allen SJ. A- and β-secretase: profound changes in alzheimer's disease. Biochem Biophys Res Commun 2002;299:373-6. (Pubitemid 35365637)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.299
, Issue.3
, pp. 373-376
-
-
Tyler, S.J.1
Dawbarn, D.2
Wilcock, G.K.3
Allen, S.J.4
-
34
-
-
34147120073
-
B-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: Implications for Alzheimer's disease pathogenesis
-
DOI 10.1523/JNEUROSCI.4396-06.2007
-
Zhao J, Fu YF, Yasvoina M, Shao PZ, Hitt B, O'Connor T, Logan S, Maus E, Citron M, Berry R, Binder L, Vassar R. B-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for alzheimer's disease pathogenesis. J Neurosci 2007;27:3639-49. (Pubitemid 46557686)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.14
, pp. 3639-3649
-
-
Zhao, J.1
Fu, Y.2
Yasvoina, M.3
Shao, P.4
Hitt, B.5
O'Connor, T.6
Logan, S.7
Maus, E.8
Citron, M.9
Berry, R.10
Binder, L.11
Vassar, R.12
-
35
-
-
0037385370
-
Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: Defining the perivascular route for the elimination of amyloid β from the human brain
-
DOI 10.1046/j.1365-2990.2003.00424.x
-
Preston SD, Steart PV, Wilkinson A, Nicoll JAR, Weller RO. Capillary and arterial cerebral amyloid angiopathy in alzheimer's disease: defining the perivascular route for the elimination of amyloid β from the human brain. Neuropathol Appl Neurobiol 2003;29:106-17. (Pubitemid 36408329)
-
(2003)
Neuropathology and Applied Neurobiology
, vol.29
, Issue.2
, pp. 106-117
-
-
Preston, S.D.1
Steart, P.V.2
Wilkinson, A.3
Nicoll, J.A.R.4
Weller, R.O.5
-
36
-
-
0031679480
-
Cerebral amyloid angiopathy: Amyloid β accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease
-
Weller RO, Massey A, Newman TA, Hutchings M, Kuo YM, Roher AE. Cerebral amyloid angiopathy - amyloid-β accumulates in putative interstitial fluid drainage pathways in alzheimer's disease. Am J Pathol 1998;153:725-33. (Pubitemid 28419027)
-
(1998)
American Journal of Pathology
, vol.153
, Issue.3
, pp. 725-733
-
-
Weller, R.O.1
Massey, A.2
Newman, T.A.3
Hutchings, M.4
Kuo, Y.-M.5
Roher, A.E.6
-
37
-
-
0035112889
-
B-amyloid efflux mediated by p-glycoprotein
-
Lam FC, Liu RH, Lu PH, Shapiro AB, Renoir JM, Sharom FJ, Reiner PB. B-amyloid efflux mediated by p-glycoprotein. J Neurochem 2001;76:1121-8.
-
(2001)
J Neurochem
, vol.76
, pp. 1121-1128
-
-
Lam, F.C.1
Liu, R.H.2
Lu, P.H.3
Shapiro, A.B.4
Renoir, J.M.5
Sharom, F.J.6
Reiner, P.B.7
-
38
-
-
0034521392
-
1-40 peptide from brain by ldl receptor-related protein-1 at the blood-brain barrier
-
1-40 peptide from brain by ldl receptor-related protein-1 at the blood-brain barrier. J Clin Invest 2000;106:1489-99.
-
(2000)
J Clin Invest
, vol.106
, pp. 1489-1499
-
-
Shibata, M.1
Yamada, S.2
Kumar, S.R.3
Calero, M.4
Bading, J.5
Frangione, B.6
Holtzman, D.M.7
Miller, C.A.8
Strickland, D.K.9
Ghiso, J.10
Zlokovic, B.V.11
-
39
-
-
27844442718
-
Aβ-degrading enzymes: Modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention
-
DOI 10.1042/BST20051101
-
Eckman EA, Eckman CB. Aβ-degrading enzymes: modulators of alzheimer's disease pathogenesis and targets for therapeutic intervention. Biochem Soc Trans 2005;33:1101-5. (Pubitemid 41659123)
-
(2005)
Biochemical Society Transactions
, vol.33
, Issue.5
, pp. 1101-1105
-
-
Eckman, E.A.1
Eckman, C.B.2
-
40
-
-
47249142795
-
Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade
-
DOI 10.1073/pnas.0710823105
-
Jacobsen JS, Comery TA, Martone RL, Elokdah H, Crandall DL, Oganesian A, Aschmies S, Kirksey Y, Gonzales C, Xu J, Zhou H, Atchison K, Wagner E, Zaleska MM, Das I, Arias RL, Bard J, Riddell D, Gardell SJ, Abou-Gharbia M, Robichaud A, Magolda R, Vlasuk GP, Bjornsson T, Reinhart PH, Pangalos MN. Enhanced clearance of aβ in brain by sustaining the plasmin proteolysis cascade. Proc Natl Acad Sci U S A 2008;105:8754-9. (Pubitemid 351987752)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.25
, pp. 8754-8759
-
-
Jacobsen, J.S.1
Comery, T.A.2
Martone, R.L.3
Elokdah, H.4
Crandall, D.L.5
Oganesian, A.6
Aschmies, S.7
Kirksey, Y.8
Gonzales, C.9
Xu, J.10
Zhou, H.11
Atchison, K.12
Wagner, E.13
Zaleska, M.M.14
Das, I.15
Arias, R.L.16
Bard, J.17
Riddell, D.18
Gardell, S.J.19
Abou-Gharbia, M.20
Robichaud, A.21
Magolda, R.22
Vlasuk, G.P.23
Bjornsson, T.24
Reinhart, P.H.25
Pangalos, M.N.26
more..
-
41
-
-
44649197748
-
Apoe promotes the proteolytic degradation of aβ
-
Jiang Q, Lee CYD, Mandrekar S, Wilkinson B, Cramer P, Zelcer N, Mann K, Lamb B, Willson TM, Collins JL, Richardson JC, Smith JD, Comery TA, Riddell D, Holtzman DM, Tontonoz P, Landreth GE. Apoe promotes the proteolytic degradation of aβ. Neuron 2008;58:681-93.
-
(2008)
Neuron
, vol.58
, pp. 681-693
-
-
Jiang, Q.1
Lee, C.Y.D.2
Mandrekar, S.3
Wilkinson, B.4
Cramer, P.5
Zelcer, N.6
Mann, K.7
Lamb, B.8
Willson, T.M.9
Collins, J.L.10
Richardson, J.C.11
Smith, J.D.12
Comery, T.A.13
Riddell, D.14
Holtzman, D.M.15
Tontonoz, P.16
Landreth, G.E.17
-
42
-
-
0037371054
-
Syncope, cerebral perfusion, and oxygenation
-
van Lieshout JJ, Wieling W, Karemaker JM, Secher NH. Syncope, cerebral perfusion, and oxygenation. J Appl Physiol 2003;94:833-48. (Pubitemid 36231994)
-
(2003)
Journal of Applied Physiology
, vol.94
, Issue.3
, pp. 833-848
-
-
Van Lieshout, J.J.1
Wieling, W.2
Karemaker, J.M.3
Secher, N.H.4
-
43
-
-
34250854130
-
Cerebrovascular function in pregnancy and eclampsia
-
DOI 10.1161/HYPERTENSIONAHA.106.079442, PII 0000426820070700000003
-
Cipolla MJ. Cerebrovascular function in pregnancy and eclampsia. Hypertension 2007;50:14-24. (Pubitemid 46986001)
-
(2007)
Hypertension
, vol.50
, Issue.1
, pp. 14-24
-
-
Cipolla, M.J.1
-
44
-
-
34347327046
-
New technologies for dissecting the arteriolar myogenic response
-
DOI 10.1016/j.tips.2007.05.006, PII S0165614707001253
-
Hill MA, Sun Z, Martinez-Lemus L, Meininger GA. New technologies for dissecting the arteriolar myogenic response. Trends Pharmacol Sci 2007;28:308-15. (Pubitemid 47016684)
-
(2007)
Trends in Pharmacological Sciences
, vol.28
, Issue.7
, pp. 308-315
-
-
Hill, M.A.1
Sun, Z.2
Martinez-Lemus, L.3
Meininger, G.A.4
-
45
-
-
84944486665
-
On the local reactions of the arterial wall to changes of internal pressure
-
Bayliss WM. On the local reactions of the arterial wall to changes of internal pressure. J Physiol-Lond 1902;28:220-31.
-
(1902)
J Physiol-Lond
, vol.28
, pp. 220-231
-
-
Bayliss, W.M.1
-
46
-
-
35548969443
-
Glial regulation of the cerebral microvasculature
-
DOI 10.1038/nn2003, PII NN2003
-
Iadecola C, Nedergaard M. Glial regulation of the cerebral microvasculature. Nat Neurosci 2007;10:1369-76. (Pubitemid 350014688)
-
(2007)
Nature Neuroscience
, vol.10
, Issue.11
, pp. 1369-1376
-
-
Iadecola, C.1
Nedergaard, M.2
-
47
-
-
0027386163
-
Localized dynamic changes in cortical blood flow with whisker stimulation corresponds to matched vascular and neuronal architecture of rat barrels
-
Cox SB, Woolsey TA, Rovainen CM. Localized dynamic changes in cortical blood-flow with whisker stimulation corresponds to matched vascular and neuronal architecture of rat barrels. J Cereb Blood Flow Metab 1993;13:899-913. (Pubitemid 23312637)
-
(1993)
Journal of Cerebral Blood Flow and Metabolism
, vol.13
, Issue.6
, pp. 899-913
-
-
Cox, S.B.1
Woolsey, T.A.2
Rovainen, C.M.3
-
48
-
-
0023840436
-
Effect of sciatic-nerve stimulation on pial arterioles in rats
-
Ngai AC, Ko KR, Morii S, Winn HR. Effect of sciatic-nerve stimulation on pial arterioles in rats. Am J Physiol 1988;254:H133-9.
-
(1988)
Am J Physiol
, vol.254
-
-
Ngai, A.C.1
Ko, K.R.2
Morii, S.3
Winn, H.R.4
-
49
-
-
17544377976
-
Early temporal characteristics of cerebral blood flow and deoxyhemoglobin changes during somatosensory stimulation
-
Silva AC, Lee SP, Iadecola C, Kim SG. Early temporal characteristics of cerebral blood flow and deoxyhemoglobin changes during somatosensory stimulation. J Cereb Blood Flow Metab 2000;20:201-6. (Pubitemid 30019846)
-
(2000)
Journal of Cerebral Blood Flow and Metabolism
, vol.20
, Issue.1
, pp. 201-206
-
-
Suva, A.C.1
Lee, S.-P.2
Iadecola, C.3
Kim, S.-G.4
-
50
-
-
2342614850
-
Neurovascular regulation in the normal brain and in Alzheimer's disease
-
Iadecola C. Neurovascular regulation in the normal brain and in alzheimer's disease. Nat Rev Neurosci 2004;5:347-60. (Pubitemid 38568496)
-
(2004)
Nature Reviews Neuroscience
, vol.5
, Issue.5
, pp. 347-360
-
-
Iadecola, C.1
-
51
-
-
0041423730
-
Interneuron Diversity series: Rhythm and mood in perisomatic inhibition
-
DOI 10.1016/S0166-2236(03)00227-3
-
Freund TF. Interneuron diversity series: rhythm and mood in perisomatic inhibition. Trends Neurosci 2003;26:489-95. (Pubitemid 37025787)
-
(2003)
Trends in Neurosciences
, vol.26
, Issue.9
, pp. 489-495
-
-
Freund, T.F.1
-
52
-
-
0033378598
-
Nitric oxide is the predominant mediator of cerebellar hyperemia during somatosensory activation in rats
-
Yang G, Chen G, Ebner TJ, Iadecola C. Nitric oxide is the predominant mediator of cerebellar hyperemia during somatosensory activation in rats. Am J Physiol-Regul Integr Comp Physiol 1999;277:R1760-70.
-
(1999)
Am J Physiol-Regul Integr Comp Physiol
, vol.277
-
-
Yang, G.1
Chen, G.2
Ebner, T.J.3
Iadecola, C.4
-
53
-
-
0037662879
-
Attenuation of activity-induced increases in cerebellar blood flow in mice lacking neuronal nitric oxide synthase
-
Yang G, Zhang Y, Ross ME, Iadecola C. Attenuation of activity-induced increases in cerebellar blood flow in mice lacking neuronal nitric oxide synthase. Am J Physiol-Heart Circul Physiol 2003;285:H298-304.
-
(2003)
Am J Physiol-Heart Circul Physiol
, vol.285
-
-
Yang, G.1
Zhang, Y.2
Ross, M.E.3
Iadecola, C.4
-
54
-
-
0034666113
-
Stellate neurons mediate functional hyperemia in the cerebellar molecular layer
-
Yang G, Huard JMT, Beitz AJ, Ross ME, Iadecola C. Stellate neurons mediate functional hyperemia in the cerebellar molecular layer. J Neurosci 2000;20:6968-73.
-
(2000)
J Neurosci
, vol.20
, pp. 6968-6973
-
-
Yang, G.1
Huard, J.M.T.2
Beitz, A.J.3
Ross, M.E.4
Iadecola, C.5
-
55
-
-
20444430784
-
Is alzheimer's disease preceded by neurodegeneration or cerebral hypoperfusion?
-
de la Torre JC. Is alzheimer's disease preceded by neurodegeneration or cerebral hypoperfusion? Ann Neurol 2005;57:783-4.
-
(2005)
Ann Neurol
, vol.57
, pp. 783-784
-
-
De La Torre, J.C.1
-
56
-
-
0034518258
-
Neuroimaging in dementia
-
DOI 10.1016/S0733-8619(05)70231-0
-
Jagust WJ. Neuroimaging in dementia. Neurol Clin 2000;18:885-901. (Pubitemid 32042601)
-
(2000)
Neurologic Clinics
, vol.18
, Issue.4
, pp. 885-901
-
-
Jagust, W.J.1
-
57
-
-
0022883420
-
Application of iodine-123-labeled isopropylamphetamine imaging to the study of dementia
-
Sharp P, Gemmell H, Cherryman G, Besson J, Crawford J, Smith F. Application of i-123 labeled isopropylamphetamine imaging to the study of dementia. J Nucl Med 1986;27:761-8. (Pubitemid 17022662)
-
(1986)
Journal of Nuclear Medicine
, vol.27
, Issue.6
, pp. 761-768
-
-
Sharp, P.1
Gemmell, H.2
Cherryman, G.3
-
58
-
-
0023097634
-
The diagnosis of dementia with single photon emission computed tomography
-
Jagust WJ, Budinger TF, Reed BR. The diagnosis of dementia with single photon-emission computed-tomography. Arch Neurol 1987;44:258-62. (Pubitemid 17031601)
-
(1987)
Archives of Neurology
, vol.44
, Issue.3
, pp. 258-262
-
-
Jagust, W.J.1
Budinger, T.F.2
Reed, B.R.3
-
59
-
-
15744380400
-
Emission tomography in dementia
-
DOI 10.1097/00006231-200503000-00003
-
Pakrasi S, O'Brien JT. Emission tomography in dementia. Nucl Med Commun 2005;26:189-96. (Pubitemid 40411042)
-
(2005)
Nuclear Medicine Communications
, vol.26
, Issue.3
, pp. 189-196
-
-
Pakrasi, S.1
O'Brien, J.T.2
-
60
-
-
71649102621
-
Cerebral blood flow in ischemic vascular dementia and alzheimer's disease, measured by arterial spin-labeling magnetic resonance imaging
-
Schuff N, Matsumoto S, Kmiecik J, Studholme C, Du A, Ezekiel F, Miller BL, Kramer JH, Jagust WJ, Chui HC, Weiner MW. Cerebral blood flow in ischemic vascular dementia and alzheimer's disease, measured by arterial spin-labeling magnetic resonance imaging. Alzheimer's Dement 2009;5:454-62.
-
(2009)
Alzheimer's Dement
, vol.5
, pp. 454-462
-
-
Schuff, N.1
Matsumoto, S.2
Kmiecik, J.3
Studholme, C.4
Du, A.5
Ezekiel, F.6
Miller, B.L.7
Kramer, J.H.8
Jagust, W.J.9
Chui, H.C.10
Weiner, M.W.11
-
61
-
-
43549110513
-
Role of imaging techniques in the diagnosis of dementia
-
O'Brien JT. Role of imaging techniques in the diagnosis of dementia. Br J Radiol 2007;80:S71-77.
-
(2007)
Br J Radiol
, vol.80
-
-
O'Brien, J.T.1
-
62
-
-
0025108733
-
Assessing utility of single photon emission computed tomography (SPECT) scan in Alzheimer disease: Correlation with cognitive severity
-
Dekosky ST, Shih WJ, Schmitt FA, Coupal J, Kirkpatrick C. Assessing utility of single photon emission computed tomography spect scan in alzheimer disease correlation with cognitive severity. Alzheimer Dis Assoc Disord 1990;4:14-23. (Pubitemid 20311746)
-
(1990)
Alzheimer Disease and Associated Disorders
, vol.4
, Issue.1
, pp. 14-23
-
-
DeKosky, S.T.1
Shih, W.-J.2
Schmitt, F.A.3
Coupal, J.4
Kirkpatrick, C.5
-
63
-
-
0032947849
-
Tc-99m HMPAO SPECT in the evaluation of Alzheimer's disease: Correlation between neuropsychiatric evaluation and CBF images
-
Imran MB, Kawashima R, Awata S, Sato K, Kinomura S, Ono S, Sato M, Fukuda H. Tc-99m hmpao spect in the evaluation of alzheimer's disease: correlation between neuropsychiatric evaluation and cbf images. J Neurol Neurosurg Psychiatry 1999;66:228-32. (Pubitemid 29103528)
-
(1999)
Journal of Neurology Neurosurgery and Psychiatry
, vol.66
, Issue.2
, pp. 228-232
-
-
Imran, M.B.1
Kawashima, R.2
Awata, S.3
Sato, K.4
Kinomura, S.5
Ono, S.6
Sato, M.7
Fukuda, H.8
-
64
-
-
1342304251
-
The relationship between cerebral blood flow and cognitive function in patients with brain insult of various etiology
-
DOI 10.1016/j.jocn.2003.02.013
-
Shiraishi H, Chang CC, Kanno H, Yamamoto I. The relationship between cerebral blood flow and cognitive function in patients with brain insult of various etiology. J Clin Neurosci 2004;11:138-41. (Pubitemid 38248411)
-
(2004)
Journal of Clinical Neuroscience
, vol.11
, Issue.2
, pp. 138-141
-
-
Shiraishi, H.1
Chang, C.-C.2
Kanno, H.3
Yamamoto, I.4
-
65
-
-
22144451172
-
The age-dependent relation of blood pressure to cognitive function and dementia
-
DOI 10.1016/S1474-4422(05)70141-1, PII S1474442205701411
-
Qiu CX, Winblad B, Fratiglioni L. The age-dependent relation of blood pressure to cognitive function and dementia. Lancet Neurol 2005;4:487-99. (Pubitemid 40982459)
-
(2005)
Lancet Neurology
, vol.4
, Issue.8
, pp. 487-499
-
-
Qiu, C.1
Winblad, B.2
Fratiglioni, L.3
-
66
-
-
33749015483
-
Update on hypertension and Alzheimer's disease
-
DOI 10.1179/016164106X130506
-
Skoog I, Gustafson D. Update on hypertension and alzheimer's disease. Neurol Res 2006;28:605-11. (Pubitemid 44444422)
-
(2006)
Neurological Research
, vol.28
, Issue.6
, pp. 605-611
-
-
Skoog, I.1
Gustafson, D.2
-
67
-
-
11344276208
-
Hypertension and the rate of cognitive decline in patients with dementia of the alzheimer type
-
Bellew KM, Pigeon JG, Stang PE, Fleischman W, Gardner RM, Baker WW. Hypertension and the rate of cognitive decline in patients with dementia of the alzheimer type. Alzheimer Dis Assoc Disord 2004;18:208-13.
-
(2004)
Alzheimer Dis Assoc Disord
, vol.18
, pp. 208-213
-
-
Bellew, K.M.1
Pigeon, J.G.2
Stang, P.E.3
Fleischman, W.4
Gardner, R.M.5
Baker, W.W.6
-
68
-
-
0034594470
-
Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death: The HAAS
-
DOI 10.1016/S0197-4580(00)00106-8, PII S0197458000001068
-
Petrovitch H, White LR, Izmirilian G, Ross GW, Havlik RJ, Markesbery W, Nelson J, Davis DG, Hardman J, Foley DJ, Launer LJ. Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death: the haas. Neurobiol Aging 2000;21:57-62. (Pubitemid 30224786)
-
(2000)
Neurobiology of Aging
, vol.21
, Issue.1
, pp. 57-62
-
-
Petrovitch, H.1
White, L.R.2
Izmirilian, G.3
Ross, G.W.4
Havlik, R.J.5
Markesbery, W.6
Nelson, J.7
Davis, D.G.8
Hardman, J.9
Foley, D.J.10
Launer, L.J.11
-
69
-
-
0029020269
-
Increased incidence of neurofibrillary tangles (nft) in nondemented individuals with hypertension
-
Sparks DL, Scheff SW, Liu HC, Landers TM, Coyne CM, Hunsaker JC. Increased incidence of neurofibrillary tangles (nft) in nondemented individuals with hypertension. J Neurol Sci 1995;131:162-9.
-
(1995)
J Neurol Sci
, vol.131
, pp. 162-169
-
-
Sparks, D.L.1
Scheff, S.W.2
Liu, H.C.3
Landers, T.M.4
Coyne, C.M.5
Hunsaker, J.C.6
-
70
-
-
3042538272
-
Midlife blood pressure and the risk of hippocampal atrophy: The Honolulu Asia aging study
-
DOI 10.1161/01.HYP.0000132475.32317.bb
-
Korf ESC, White LR, Scheltens P, Launer LJ. Midlife blood pressure and the risk of hippocampal atrophy - the honolulu asia aging study. Hypertension 2004;44:29-34. (Pubitemid 38823483)
-
(2004)
Hypertension
, vol.44
, Issue.1
, pp. 29-34
-
-
Korf, E.S.C.1
White, L.R.2
Scheltens, P.3
Launer, L.J.4
-
71
-
-
12544254102
-
Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe
-
den Heijer T, Launer LJ, Prins ND, van Dijk EJ, Vermeer SE, Hofman A, Koudstaal PJ, Breteler MMB. Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe. Neurology 2005;64:263-7.
-
(2005)
Neurology
, vol.64
, pp. 263-267
-
-
Den Heijer, T.1
Launer, L.J.2
Prins, N.D.3
Van Dijk, E.J.4
Vermeer, S.E.5
Hofman, A.6
Koudstaal, P.J.7
Breteler, M.M.B.8
-
72
-
-
0035897938
-
Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study
-
Kivipelto M, Helkala EL, Laakso MP, Hanninen T, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissien A. Midlife vascular risk factors and alzheimer's disease in later life: longitudinal, population based study. Br Med J 2001;322:1447-51. (Pubitemid 32575406)
-
(2001)
British Medical Journal
, vol.322
, Issue.7300
, pp. 1447-1451
-
-
Kivipelto, M.1
Helkala, E.-L.2
Laakso, M.P.3
Hanninen, T.4
Hallikainen, M.5
Alhainen, K.6
Soininen, H.7
Tuomilehto, J.8
Nissien, A.9
-
73
-
-
75649144979
-
Role of vascular risk factors and vascular dysfunction in alzheimer's disease
-
Dickstein DL, Walsh J, Brautigam H, Stockton SD, Gandy S, Hof PR. Role of vascular risk factors and vascular dysfunction in alzheimer's disease. Mt Sinai J Med 2010;77:82-102.
-
(2010)
Mt Sinai J Med
, vol.77
, pp. 82-102
-
-
Dickstein, D.L.1
Walsh, J.2
Brautigam, H.3
Stockton, S.D.4
Gandy, S.5
Hof, P.R.6
-
74
-
-
0032764016
-
Diabetes mellitus and the risk of dementia - The rotterdam study
-
Ott A, Stolk RP, van Harskamp F, Pols HAP, Hofman A, Breteler MMB. Diabetes mellitus and the risk of dementia - the rotterdam study. Neurology 1999;53:1937-42.
-
(1999)
Neurology
, vol.53
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
Van Harskamp, F.3
Pols, H.A.P.4
Hofman, A.5
Breteler, M.M.B.6
-
75
-
-
0031054674
-
Brain infarction and the clinical expression of alzheimer disease - The nun study
-
Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA, Markesbery WR. Brain infarction and the clinical expression of alzheimer disease - the nun study. JAMA-J Am Med Assoc 1997;277:813-7.
-
(1997)
JAMA-J Am Med Assoc
, vol.277
, pp. 813-817
-
-
Snowdon, D.A.1
Greiner, L.H.2
Mortimer, J.A.3
Riley, K.P.4
Greiner, P.A.5
Markesbery, W.R.6
-
76
-
-
20444383813
-
Cerebral hypoperfusion and clinical onset of dementia: The Rotterdam Study
-
DOI 10.1002/ana.20493
-
Ruitenberg A, Heijer Td, Bakker SLM, Swieten JCv, Koudstaal PJ, Hofman A, Breteler MMB. Cerebral hypoperfusion and clinical onset of dementia: the rotterdam study. Ann Neurol 2005;57:789-94. (Pubitemid 40798616)
-
(2005)
Annals of Neurology
, vol.57
, Issue.6
, pp. 789-794
-
-
Ruitenberg, A.1
Den, H.T.2
Bakker, S.L.M.3
Van Swieten, J.C.4
Koudstaal, P.J.5
Hofman, A.6
Breteler, M.M.B.7
-
77
-
-
0028350718
-
Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders
-
DOI 10.1007/s004010050112
-
Buee L, Hof PR, Bouras C, Delacourte A, Perl DP, Morrison JH, Fillit HM. Pathological alterations of the cerebral microvasculature in alzheimers-disease and related dementing disorders. Acta Neuropathol (Berl) 1994;87:469-80. (Pubitemid 24128974)
-
(1994)
Acta Neuropathologica
, vol.87
, Issue.5
, pp. 469-480
-
-
Buee, L.1
Hof, P.R.2
Bouras, C.3
Delacourte, A.4
Perl, D.P.5
Morrison, J.H.6
Fillit, H.M.7
-
78
-
-
0033363939
-
Sod1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
-
Iadecola C, Zhang FY, Niwa K, Eckman C, Turner SK, Fischer E, Younkin S, Borchelt DR, Hsiao KK, Carlson GA. Sod1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein. Nat Neurosci 1999;2:157-61.
-
(1999)
Nat Neurosci
, vol.2
, pp. 157-161
-
-
Iadecola, C.1
Zhang, F.Y.2
Niwa, K.3
Eckman, C.4
Turner, S.K.5
Fischer, E.6
Younkin, S.7
Borchelt, D.R.8
Hsiao, K.K.9
Carlson, G.A.10
-
79
-
-
0036302636
-
Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein
-
Niwa K, Kazama K, Younkin L, Younkin SG, Carlson GA, Iadecola C. Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein. Am J Physiol-Heart Circul Physiol 2002;283:H315-23.
-
(2002)
Am J Physiol-Heart Circul Physiol
, vol.283
-
-
Niwa, K.1
Kazama, K.2
Younkin, L.3
Younkin, S.G.4
Carlson, G.A.5
Iadecola, C.6
-
80
-
-
0036176504
-
Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor protein
-
Niwa K, Kazama K, Younkin SG, Carlson GA, Iadecola C. Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor protein. Neurobiol Dis 2002;9:61-8.
-
(2002)
Neurobiol Dis
, vol.9
, pp. 61-68
-
-
Niwa, K.1
Kazama, K.2
Younkin, S.G.3
Carlson, G.A.4
Iadecola, C.5
-
81
-
-
0016368754
-
Blood flow metabolism couple in brain
-
Reivich M. Blood flow metabolism couple in brain. Res Publ Assoc Res Nerv Ment Dis 1974;53:125-40.
-
(1974)
Res Publ Assoc Res Nerv Ment Dis
, vol.53
, pp. 125-140
-
-
Reivich, M.1
-
82
-
-
0017368491
-
14C]deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthetized albino rat
-
Sokoloff L, Reivich M, Kennedy C, Desrosiers MH, Patlak CS, Pettigrew KD, Sakurada O, Shinohara M. Deoxyglucose-c-14 method for measurement of local cerebral glucose-utilization - theory, procedure, and normal values in conscious and anesthetized albino-rat. J Neurochem 1977;28:897-916. (Pubitemid 8098854)
-
(1977)
Journal of Neurochemistry
, vol.28
, Issue.5
, pp. 897-916
-
-
Sokoloff, L.1
Reivich, M.2
Kennedy, C.3
-
83
-
-
0037461347
-
Mild cognitive impairment - Can fdg-pet predict who is to rapidly convert to alzheimer's disease?
-
Chetelat G, Desgranges B, de la Sayette V, Viader F, Eustache F, Baron JC. Mild cognitive impairment - can fdg-pet predict who is to rapidly convert to alzheimer's disease? Neurology 2003;60:1374-7.
-
(2003)
Neurology
, vol.60
, pp. 1374-1377
-
-
Chetelat, G.1
Desgranges, B.2
De La Sayette, V.3
Viader, F.4
Eustache, F.5
Baron, J.C.6
-
84
-
-
33645788000
-
Brain imaging evidence of preclinical alzheimer's disease in normal aging
-
Jagust W, Gitcho A, Sun F, Kuczynski B, Mungas D, Haan M. Brain imaging evidence of preclinical alzheimer's disease in normal aging. Ann Neurol 2006;59:673-81.
-
(2006)
Ann Neurol
, vol.59
, pp. 673-681
-
-
Jagust, W.1
Gitcho, A.2
Sun, F.3
Kuczynski, B.4
Mungas, D.5
Haan, M.6
-
85
-
-
0035824167
-
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome
-
Silverman DHS, Small GW, Chang CY, Lu CS, de Aburto MAK, Chen W, Czernin J, Rapoport SI, Pietrini P, Alexander GE, Schapiro MB, Jagust WJ, Hoffman JM, Welsh-Bohmer KA, Alavi A, Clark CM, Salmon E, de Leon MJ, Mielke R, Cummings JL, Kowell AP, Gambhir SS, Hoh CK, Phelps ME. Positron emission tomography in evaluation of dementia - regional brain metabolism and long-term outcome. JAMA-J Am Med Assoc 2001;286:2120-7. (Pubitemid 34041597)
-
(2001)
Journal of the American Medical Association
, vol.286
, Issue.17
, pp. 2120-2127
-
-
Silverman, D.H.S.1
Small, G.W.2
Chang, C.Y.3
Lu, C.S.4
De Kung, A.M.A.5
Chen, W.6
Czernin, J.7
Rapoport, S.I.8
Pietrini, P.9
Alexander, G.E.10
Schapiro, M.B.11
Jagust, W.J.12
Hoffman, J.M.13
Welsh-Bohmer, K.A.14
Alavi, A.15
Clark, C.M.16
Salmon, E.17
De Leon, M.J.18
Mielke, R.19
Cummings, J.L.20
Kowell, A.P.21
Gambhir, S.S.22
Hoh, C.K.23
Phelps, M.E.24
more..
-
86
-
-
0030874251
-
Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease
-
DOI 10.1002/ana.410420114
-
Minoshima S, Giordani B, Berent S, Frey KA, Foster NL, Kuhl DE. Metabolic reduction in the posterior cingulate cortex in very early alzheimer's disease. Ann Neurol 1997;42:85-94. (Pubitemid 27304784)
-
(1997)
Annals of Neurology
, vol.42
, Issue.1
, pp. 85-94
-
-
Minoshima, S.1
Giordani, B.2
Berent, S.3
Frey, K.A.4
Foster, N.L.5
Kuhl, D.E.6
-
87
-
-
0037645793
-
PET studies in dementia
-
Herholz K. Pet studies in dementia. Ann Nucl Med 2003;17:79-89. (Pubitemid 36693059)
-
(2003)
Annals of Nuclear Medicine
, vol.17
, Issue.2
, pp. 79-89
-
-
Herholz, K.1
-
88
-
-
34548219060
-
What does fluorodeoxyglucose pet imaging add to a clinical diagnosis of dementia?
-
Jagust W, Reed B, Mungas D, Ellis W, DeCarli C. What does fluorodeoxyglucose pet imaging add to a clinical diagnosis of dementia? Neurology 2007;69:871-7.
-
(2007)
Neurology
, vol.69
, pp. 871-877
-
-
Jagust, W.1
Reed, B.2
Mungas, D.3
Ellis, W.4
DeCarli, C.5
-
89
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
DOI 10.1126/science.274.5284.99
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang FS, Cole G. Correlative memory deficits, aβ elevation, and amyloid plaques in transgenic mice. Science 1996;274:99-102. (Pubitemid 26332733)
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
90
-
-
0028810244
-
Age-related cns disorder and early death in transgenic fvb/n mice overexpressing alzheimer amyloid precursor proteins
-
Hsiao KK, Borchelt DR, Olson K, Johannsdottir R, Kitt C, Yunis W, Xu S, Eckman C, Younkin S, Price D, Iadecola C, Clark HB, Carlson G. Age-related cns disorder and early death in transgenic fvb/n mice overexpressing alzheimer amyloid precursor proteins. Neuron 1995;15:1203-18.
-
(1995)
Neuron
, vol.15
, pp. 1203-1218
-
-
Hsiao, K.K.1
Borchelt, D.R.2
Olson, K.3
Johannsdottir, R.4
Kitt, C.5
Yunis, W.6
Xu, S.7
Eckman, C.8
Younkin, S.9
Price, D.10
Iadecola, C.11
Clark, H.B.12
Carlson, G.13
-
91
-
-
60349096101
-
Reduction of the cerebrovascular volume in a transgenic mouse model of alzheimer's disease
-
Bourasset F, Ouellett M, Tremblay C, Julien C, Do TM, Oddo S, LaFerla F, Calon F. Reduction of the cerebrovascular volume in a transgenic mouse model of alzheimer's disease. Neuropharmacology 2009;56:808-13.
-
(2009)
Neuropharmacology
, vol.56
, pp. 808-813
-
-
Bourasset, F.1
Ouellett, M.2
Tremblay, C.3
Julien, C.4
Do, T.M.5
Oddo, S.6
LaFerla, F.7
Calon, F.8
-
92
-
-
0032032969
-
Characteristics of the in vitro vasoactivity of β-amyloid peptides
-
DOI 10.1006/exnr.1997.6743
-
Crawford F, Suo ZM, Fang CH, Mullan M. Characteristics of the in vitro vasoactivity of β-amyloid peptides. Exp Neurol 1998;150:159-68. (Pubitemid 28146435)
-
(1998)
Experimental Neurology
, vol.150
, Issue.1
, pp. 159-168
-
-
Crawford, F.1
Suo, Z.2
Fang, C.3
Mullan, M.4
-
93
-
-
0034940552
-
Physiological levels of β-amyloid induce cerebral vessel dysfunction and reduce endothelial nitric oxide production
-
DOI 10.1179/016164101101198758
-
Price JM, Chi XD, Hellermann G, Sutton ET. Physiological levels of β-amyloid induce cerebral vessel dysfunction and reduce endothelial nitric oxide production. Neurol Res 2001;23:506-12. (Pubitemid 32642784)
-
(2001)
Neurological Research
, vol.23
, Issue.5
, pp. 506-512
-
-
Price, J.M.1
Chi, X.2
Hellermann, G.3
Sutton, E.T.4
-
94
-
-
0030929498
-
B-Amyloid induces cerebrovascular endothelial dysfunction in the rat brain
-
Price JM, Sutton ET, Hellermann A, Thomas T. B-amyloid induces cerebrovascular endothelial dysfunction in the rat brain. Neurol Res 1997;19:534-8. (Pubitemid 27419426)
-
(1997)
Neurological Research
, vol.19
, Issue.5
, pp. 534-538
-
-
Price, J.M.1
Sutton, E.T.2
Hellermann, A.3
Thomas, T.4
-
95
-
-
0033622480
-
1-40 reproduces cerebrovascular alterations resulting from amyloid precursor protein overexpression in mice
-
1-40 reproduces cerebrovascular alterations resulting from amyloid precursor protein overexpression in mice. J Cereb Blood Flow Metab 2000;20:1659-68.
-
(2000)
J Cereb Blood Flow Metab
, vol.20
, pp. 1659-1668
-
-
Niwa, K.1
Carlson, G.A.2
Iadecola, C.3
-
96
-
-
0035665509
-
Aβ-peptides enhance vasoconstriction in cerebral circulation
-
Niwa K, Porter VA, Kazama K, Cornfield D, Carlson GA, Iadecola C. Aβ-peptides enhance vasoconstriction in cerebral circulation. Am J Physiol-Heart Circul Physiol 2001;281:H2417-24.
-
(2001)
Am J Physiol-Heart Circul Physiol
, vol.281
-
-
Niwa, K.1
Porter, V.A.2
Kazama, K.3
Cornfield, D.4
Carlson, G.A.5
Iadecola, C.6
-
97
-
-
0029670094
-
B-amyloid-mediated vasoactivity and vascular endothelial damage
-
Thomas T, Thomas G, McLendon C, Sutton T, Mullan M. B-amyloid-mediated vasoactivity and vascular endothelial damage. Nature 1996;380:168-71.
-
(1996)
Nature
, vol.380
, pp. 168-171
-
-
Thomas, T.1
Thomas, G.2
McLendon, C.3
Sutton, T.4
Mullan, M.5
-
98
-
-
0030991218
-
Cerebrovascular endothelial dysfunction mediated by β-amyloid
-
Thomas T, McLendon C, Sutton ET, Thomas G. Cerebrovascular endothelial dysfunction mediated by β-amyloid. Neuroreport 1997;8:1387-91. (Pubitemid 27242542)
-
(1997)
NeuroReport
, vol.8
, Issue.6
, pp. 1387-1391
-
-
Thomas, T.1
McLendon, C.2
Sutton, E.T.3
Thomas, G.4
-
99
-
-
9144223132
-
Mechanisms of soluble β-amyloid impairment of endothelial function
-
DOI 10.1074/jbc.M407358200
-
Gentile MT, Vecchione C, Maffei A, Aretini A, Marino G, Poulet R, Capobianco L, Selvetella G, Lembo G. Mechanisms of soluble β-amyloid impairment of endothelial function. J Biol Chem 2004;279:48135-42. (Pubitemid 39540968)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.46
, pp. 48135-48142
-
-
Gentile, M.T.1
Vecchione, C.2
Maffei, A.3
Aretini, A.4
Marino, G.5
Poulet, R.6
Capobianco, L.7
Selvetella, G.8
Lembot, G.9
-
100
-
-
48949115623
-
Non-invasive characterization of β-amyloid(1-40) vasoactivity by functional magnetic resonance imaging in mice
-
Luo F, Seifert TR, Edalji R, Loebbert RW, Hradil VP, Harlan J, Schmidt M, Nimmirich V, Cox BF, Fox GB. Non-invasive characterization of β-amyloid(1-40) vasoactivity by functional magnetic resonance imaging in mice. Neuroscience 2008;155:263-9.
-
(2008)
Neuroscience
, vol.155
, pp. 263-269
-
-
Luo, F.1
Seifert, T.R.2
Edalji, R.3
Loebbert, R.W.4
Hradil, V.P.5
Harlan, J.6
Schmidt, M.7
Nimmirich, V.8
Cox, B.F.9
Fox, G.B.10
-
101
-
-
73949094104
-
Long-term incubation with β-amyloid peptides impairs endothelium-dependent vasodilatation in isolated rat basilar artery
-
Chisari M, Merlo S, Sortino MA, Salomone S. Long-term incubation with β-amyloid peptides impairs endothelium-dependent vasodilatation in isolated rat basilar artery. Pharmacol Res 2010;61:157-61.
-
(2010)
Pharmacol Res
, vol.61
, pp. 157-161
-
-
Chisari, M.1
Merlo, S.2
Sortino, M.A.3
Salomone, S.4
-
102
-
-
77950671610
-
Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells
-
Dietrich H, Xiang C, Han B, Zipfel G, Holtzman D. Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells. Molecular Neurodegeneration 2010;5:15.
-
(2010)
Molecular Neurodegeneration
, vol.5
, pp. 15
-
-
Dietrich, H.1
Xiang, C.2
Han, B.3
Zipfel, G.4
Holtzman, D.5
-
103
-
-
0022456638
-
Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor
-
Rubanyi GM, Vanhoutte PM. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol 1986;250:H822-7.
-
(1986)
Am J Physiol
, vol.250
-
-
Rubanyi, G.M.1
Vanhoutte, P.M.2
-
104
-
-
0031869301
-
Role of peroxynitrite in the vasoactive and cytotoxic effects of alzheimer's β-amyloid(1-40) peptide
-
Paris D, Parker TA, Town T, Suo ZM, Fang CH, Humphrey J, Crawford F, Mullan M. Role of peroxynitrite in the vasoactive and cytotoxic effects of alzheimer's β-amyloid(1-40) peptide. Exp Neurol 1998;152:116-22.
-
(1998)
Exp Neurol
, vol.152
, pp. 116-122
-
-
Paris, D.1
Parker, T.A.2
Town, T.3
Suo, Z.M.4
Fang, C.H.5
Humphrey, J.6
Crawford, F.7
Mullan, M.8
-
105
-
-
0036447712
-
Proinflammatory and vasoactive effects of Abeta in the cerebrovasculature
-
Townsend KP, Obregon D, Quadros A, Patel N, Volmar C, Paris D, Mullan M. Proinflammatory and vasoactive effects of a beta in the cerebrovasculature. Alzheimer's Dis: Vasc Etiol Pathol 2002;977:65-76. (Pubitemid 35418137)
-
(2002)
Annals of the New York Academy of Sciences
, vol.977
, pp. 65-76
-
-
Townsend, K.P.1
Obregon, D.2
Quadros, A.3
Patel, N.4
Volmar, C.5
Paris, D.6
Mullan, M.7
-
106
-
-
0034603601
-
Soluble β-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway
-
DOI 10.1016/S0197-4580(99)00111-6, PII S0197458099001116
-
Paris D, Town T, Mori T, Parker TA, Humphrey J, Mullan M. Soluble β-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway. Neurobiol Aging 2000;21:183-97. (Pubitemid 30387077)
-
(2000)
Neurobiology of Aging
, vol.21
, Issue.2
, pp. 183-197
-
-
Paris, D.1
Town, T.2
Mori, T.3
Parker, T.A.4
Humphrey, J.5
Mullan, M.6
-
107
-
-
0042387969
-
Vasoactive effects of Aβ in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: Role of inflammation
-
DOI 10.1179/016164103101201940
-
Paris D, Humphrey J, Quadros A, Patel N, Crescentini R, Crawford F, Mullan M. Vasoactive effects of aβ in isolated human cerebrovessels and in a transgenic mouse model of alzheimer's disease: role of inflammation. Neurol Res 2003;25:642-51. (Pubitemid 37087609)
-
(2003)
Neurological Research
, vol.25
, Issue.6
, pp. 642-651
-
-
Paris, D.1
Humphrey, J.2
Quadros, A.3
Patel, N.4
Crescentini, R.5
Crawford, F.6
Mullan, M.7
-
108
-
-
77956497978
-
Endothelin-converting enzyme-1 in alzheimer's disease and vascular dementia
-
Palmer JC, Kehoe PG, Love S. Endothelin-converting enzyme-1 in alzheimer's disease and vascular dementia. Neuropathol Appl Neurobiol 2010;36:487-97.
-
(2010)
Neuropathol Appl Neurobiol
, vol.36
, pp. 487-497
-
-
Palmer, J.C.1
Kehoe, P.G.2
Love, S.3
-
109
-
-
67649984550
-
Endothelin-converting enzyme-2 is increased in alzheimer's disease and up-regulated by aβ
-
Palmer JC, Baig S, Kehoe PG, Love S. Endothelin-converting enzyme-2 is increased in alzheimer's disease and up-regulated by aβ. Am J Pathol 2009;175:262-70.
-
(2009)
Am J Pathol
, vol.175
, pp. 262-270
-
-
Palmer, J.C.1
Baig, S.2
Kehoe, P.G.3
Love, S.4
-
110
-
-
0029017876
-
Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon- sensitive metalloprotease with acidic ph optimum
-
Emoto N, Yanagisawa M. Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic ph optimum. J Biol Chem 1995;270:15262-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 15262-15268
-
-
Emoto, N.1
Yanagisawa, M.2
-
111
-
-
0035816707
-
Degradation of the alzheimer's amyloid-β peptide by endothelin-converting enzyme
-
Eckman EA, Reed DK, Eckman CB. Degradation of the alzheimer's amyloid-β peptide by endothelin-converting enzyme. J Biol Chem 2001;276:24540-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 24540-24548
-
-
Eckman, E.A.1
Reed, D.K.2
Eckman, C.B.3
-
112
-
-
0034086055
-
Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development
-
Yanagisawa H, Hammer RE, Richardson JA, Emoto N, Williams SC, Takeda S, Clouthier DE, Yanagisawa M. Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development. J Clin Invest 2000;105:1373-82. (Pubitemid 30322403)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.10
, pp. 1373-1382
-
-
Yanagisawa, H.1
Hammer, R.E.2
Richardson, J.A.3
Emoto, N.4
Clay, W.S.5
Takeda, S.-I.6
Clouthier, D.E.7
Yanagisawa, M.8
-
113
-
-
0037462769
-
Alzheimer's disease β-amyloid peptide is increased in mice deficient in endothelin-converting enzyme
-
DOI 10.1074/jbc.C200642200
-
Eckman EA, Watson M, Marlow L, Sambamurti K, Eckman CB. Alzheimer's disease β-amyloid peptide is increased in mice deficient in endothelin-converting enzyme. J Biol Chem 2003;278:2081-4. (Pubitemid 36801269)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.4
, pp. 2081-2084
-
-
Eckman, E.A.1
Watson, M.2
Marlow, L.3
Sambamurti, K.4
Eckman, C.B.5
-
114
-
-
42549111585
-
Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory
-
DOI 10.1111/j.1601-183X.2007.00365.x
-
Rodriguiz RM, Gadnidze K, Ragnauth A, Dorr N, Yanagisawa M, Wetsel WC, Devi LA. Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory. Genes Brain Behav 2008;7:418-26. (Pubitemid 351590928)
-
(2008)
Genes, Brain and Behavior
, vol.7
, Issue.4
, pp. 418-426
-
-
Rodriguiz, R.M.1
Gadnidze, K.2
Ragnauth, A.3
Dorr, N.4
Yanagisawa, M.5
Wetsel, W.C.6
Devi, L.A.7
-
116
-
-
0037703255
-
RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain
-
DOI 10.1038/nm890
-
Deane R, Yan SD, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, Armstrong DL, Arnold B, Liliensiek B, Nawroth P, Hofman F, Kindy M, Stern D, Zlokovic B. Rage mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain. Nat Med 2003;9:907-13. (Pubitemid 36889934)
-
(2003)
Nature Medicine
, vol.9
, Issue.7
, pp. 907-913
-
-
Deane, R.1
Yan, S.D.2
Submamaryan, R.K.3
LaRue, B.4
Jovanovic, S.5
Hogg, E.6
Welch, D.7
Manness, L.8
Lin, C.9
Yu, J.10
Zhu, H.11
Ghiso, J.12
Frangione, B.13
Stern, A.14
Schmidt, A.M.15
Armstrong, D.L.16
Arnold, B.17
Liliensiek, B.18
Nawroth, P.19
Hofman, F.20
Kindy, M.21
Stern, D.22
Zlokovic, B.23
more..
-
117
-
-
84866633594
-
Aβ induces endothelin-1 production by sh-sy5y neuroblastoma cells
-
Palmer J, Kehoe P, Love S. Aβ induces endothelin-1 production by sh-sy5y neuroblastoma cells. Brain Pathol 2010;20(suppl 1):18.
-
(2010)
Brain Pathol
, vol.20
, Issue.SUPPL. 1
, pp. 18
-
-
Palmer, J.1
Kehoe, P.2
Love, S.3
-
118
-
-
84866625831
-
Et-1 is elevated in the brain in ad and its neuronal production and release are upregulated by aβ1-42
-
Palmer J, Kehoe P, Love S. Et-1 is elevated in the brain in ad and its neuronal production and release are upregulated by aβ1-42. Neuropathol Appl Neurobiol 2011;37(Suppl. 1):34.
-
(2011)
Neuropathol Appl Neurobiol
, vol.37
, Issue.SUPPL. 1
, pp. 34
-
-
Palmer, J.1
Kehoe, P.2
Love, S.3
-
119
-
-
24644523381
-
Localisation of endothelin-1 and its receptors in vascular tissue as seen at the electron microscopic level
-
DOI 10.2174/157016105774329381
-
Loesch A. Localisation of endothelin-1 and its receptors in vascular tissue as seen at the electron microscopic level. Curr Vasc Pharmacol 2005;3:381-92. (Pubitemid 41264291)
-
(2005)
Current Vascular Pharmacology
, vol.3
, Issue.4
, pp. 381-392
-
-
Loesch, A.1
-
120
-
-
0034020349
-
Neural endothelin in hypertension: Increased expression in ganglia and nerves to cerebral arteries of the spontaneously hypertensive rat
-
Milner P, Loesch A, Burnstock G. Neural endothelin in hypertension: increased expression in ganglia and nerves to cerebral arteries of the spontaneously hypertensive rat. J Vasc Res 2000;37:39-49. (Pubitemid 30158040)
-
(2000)
Journal of Vascular Research
, vol.37
, Issue.1
, pp. 39-49
-
-
Milner, P.1
Loesch, A.2
Burnstock, G.3
-
121
-
-
67649665617
-
Angiotensin-converting enzyme levels and activity in alzheimer's disease: Differences in brain and csf ace and association with ace1 genotypes
-
Miners JS, Ashby EL, Baig S, Harrison R, Tayler H, Speedy E, Prince JA, Love S, Kehoe PG. Angiotensin-converting enzyme levels and activity in alzheimer's disease: differences in brain and csf ace and association with ace1 genotypes. Am J Transl Res 2009;1:163-77.
-
(2009)
Am J Transl Res
, vol.1
, pp. 163-177
-
-
Miners, J.S.1
Ashby, E.L.2
Baig, S.3
Harrison, R.4
Tayler, H.5
Speedy, E.6
Prince, J.A.7
Love, S.8
Kehoe, P.G.9
-
122
-
-
70450257558
-
Aβ42-to-aβ40-and angiotensin-converting activities in different domains of angiotensin-converting enzyme
-
Zou K, Maeda T, Watanabe A, Liu J, Liu S, Oba R, Satoh Y-I, Komano H, Michikawa M. Aβ42-to-aβ40-and angiotensin-converting activities in different domains of angiotensin-converting enzyme. J Biol Chem 2009;284:31914-20.
-
(2009)
J Biol Chem
, vol.284
, pp. 31914-31920
-
-
Zou, K.1
Maeda, T.2
Watanabe, A.3
Liu, J.4
Liu, S.5
Oba, R.6
Satoh, Y.-I.7
Komano, H.8
Michikawa, M.9
-
123
-
-
27844534846
-
Amyloid β-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor
-
DOI 10.1074/jbc.M508460200
-
Hemming ML, Selkoe DJ. Amyloid β-protein is degraded by cellular angiotensin-converting enzyme (ace) and elevated by an ace inhibitor. J Biol Chem 2005;280:37644-50. (Pubitemid 41642372)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.45
, pp. 37644-37650
-
-
Hemming, M.L.1
Selkoe, D.J.2
-
124
-
-
70450045976
-
Angiotensins in alzheimer's disease - Friend or foe?
-
Kehoe PG, Miners S, Love S. Angiotensins in alzheimer's disease - friend or foe? Trends Neurosci 2009;32:619-28.
-
(2009)
Trends Neurosci
, vol.32
, pp. 619-628
-
-
Kehoe, P.G.1
Miners, S.2
Love, S.3
-
125
-
-
0036993442
-
A clinical overview of cholinesterase inhibitors in Alzheimer's disease
-
DOI 10.1017/S1041610203008688
-
Farlow M. A clinical overview of cholinesterase inhibitors in alzheimer's disease. Int Psychogeriatr 2002;14:93-126. (Pubitemid 36206093)
-
(2002)
International Psychogeriatrics
, vol.14
, Issue.SUPPL. 1
, pp. 93-126
-
-
Farlow, M.1
-
126
-
-
0037371279
-
Use of cholinesterase inhibitors in clinical practice: Evidence-based recommendations
-
DOI 10.1176/appi.ajgp.11.2.131
-
Cummings JL. Use of cholinesterase inhibitors in clinical practice - evidence-based recommendations. Am J Geriatr Psychiatry 2003;11:131-45. (Pubitemid 36254187)
-
(2003)
American Journal of Geriatric Psychiatry
, vol.11
, Issue.2
, pp. 131-145
-
-
Cummings, J.L.1
-
128
-
-
33750329955
-
Clinical practice with anti-dementia drugs: A consensus statement from British Association for Psychopharmacology
-
DOI 10.1177/0269881106068299
-
Burns A, O'Brien J. Clinical practice with anti-dementia drugs: a consensus statement from british association for psychopharmacology. J Psychopharmacol (Oxf) 2006;20:732-55. (Pubitemid 44622739)
-
(2006)
Journal of Psychopharmacology
, vol.20
, Issue.6
, pp. 732-755
-
-
Burns, A.1
O'Brien, J.2
-
129
-
-
4444382035
-
Utilizing combination therapy in the treatment of Alzheimer's disease
-
DOI 10.1586/14737175.4.5.799
-
Farlow MR. Utilizing combination therapy in the treatment of alzheimer's disease. Expert Rev Neurother 2004;4:799-808. (Pubitemid 39186685)
-
(2004)
Expert Review of Neurotherapeutics
, vol.4
, Issue.5
, pp. 799-808
-
-
Farlow, M.R.1
-
131
-
-
43049129669
-
Treatment options in Alzheimer's disease: Maximizing benefit, managing expectations
-
DOI 10.1159/000122962
-
Farlow MR, Miller ML, Pejovic V. Treatment options in alzheimer's disease: maximizing benefit, managing expectations. Dement Geriatr Cogn Disord 2008;25:408-22. (Pubitemid 351630074)
-
(2008)
Dementia and Geriatric Cognitive Disorders
, vol.25
, Issue.5
, pp. 408-422
-
-
Farlow, M.R.1
Miller, M.L.2
Pejovic, V.3
-
132
-
-
33750579926
-
Enhanced brain activity may precede the diagnosis of alzheimer's disease by 30 years
-
Mondadori CRA, Buchmann A, Mustovic H, Schmidt CF, Boesiger P, Nitsch RM, Hock C, Streffer J, Henke K. Enhanced brain activity may precede the diagnosis of alzheimer's disease by 30 years. Brain 2006;129:2908-22.
-
(2006)
Brain
, vol.129
, pp. 2908-2922
-
-
Mondadori, C.R.A.1
Buchmann, A.2
Mustovic, H.3
Schmidt, C.F.4
Boesiger, P.5
Nitsch, R.M.6
Hock, C.7
Streffer, J.8
Henke, K.9
-
133
-
-
0029979798
-
Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease
-
GomezIsla T, Price JL, McKeel DW, Morris JC, Growdon JH, Hyman BT. Profound loss of layer ii entorhinal cortex neurons occurs in very mild alzheimer's disease. J Neurosci 1996;16:4491-500. (Pubitemid 26243044)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.14
, pp. 4491-4500
-
-
Gomez-Isla, T.1
Price, J.L.2
McKeel Jr., D.W.3
Morris, J.C.4
Growdon, J.H.5
Hyman, B.T.6
-
134
-
-
0029892175
-
Cerebral amyloid deposition and diffuse plaques in "normal" aging: Evidence for presymptomatic and very mild alzheimer's disease
-
Morris JC, Storandt M, McKeel DW, Rubin EH, Price JL, Grant EA, Berg L. Cerebral amyloid deposition and diffuse plaques in "normal" aging: evidence for presymptomatic and very mild alzheimer's disease. Neurology 1996;46:707-19.
-
(1996)
Neurology
, vol.46
, pp. 707-719
-
-
Morris, J.C.1
Storandt, M.2
McKeel, D.W.3
Rubin, E.H.4
Price, J.L.5
Grant, E.A.6
Berg, L.7
-
135
-
-
1842510004
-
Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain
-
Ingelsson M, Fukumoto H, Newell KL, Growdon JH, Hedley-Whyte ET, Frosch MP, Albert MS, Hyman BT, Irizarry MC. Early aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in ad brain. Neurology 2004;62:925-31. (Pubitemid 38435780)
-
(2004)
Neurology
, vol.62
, Issue.6
, pp. 925-931
-
-
Ingelsson, M.1
Fukumoto, H.2
Newell, K.L.3
Growdon, J.H.4
Hedley-Whyte, E.T.5
Frosch, M.P.6
Albert, M.S.7
Hyman, B.T.8
Irizarry, M.C.9
-
136
-
-
77956229704
-
Neuropathology after active aβ42 immunotherapy: Implications for alzheimer's disease pathogenesis
-
Berl
-
Boche D, Denham N, Holmes C, Nicoll JAR. Neuropathology after active aβ42 immunotherapy: implications for alzheimer's disease pathogenesis. Acta Neuropathol (Berl) 2010:120.
-
(2010)
Acta Neuropathol
, pp. 120
-
-
Boche, D.1
Denham, N.2
Holmes, C.3
Nicoll, J.A.R.4
-
137
-
-
47149112621
-
42 immunisation in alzheimer's disease: Follow-up of a randomised, placebo-controlled phase i trial
-
42 immunisation in alzheimer's disease: follow-up of a randomised, placebo-controlled phase i trial. Lancet 2008;372:216-23.
-
(2008)
Lancet
, vol.372
, pp. 216-223
-
-
Holmes, C.1
Boche, D.2
Wilkinson, D.3
Yadegarfar, G.4
Hopkins, V.5
Bayer, A.6
Jones, R.W.7
Bullock, R.8
Love, S.9
Neal, J.W.10
Zotova, E.11
Nicoll, J.A.R.12
-
138
-
-
40449135167
-
B-amyloid burden is not associated with rates of brain atrophy
-
DOI 10.1002/ana.21223
-
Josephs KA, Whitwell JL, Ahmed Z, Shiung MM, Weigand SD, Knopman DS, Boeve BF, Parisi JE, Petersen RC, Dickson DW, Jack CR. B-amyloid burden is not associated with rates of brain atrophy. Ann Neurol 2008;63:204-12. (Pubitemid 351355299)
-
(2008)
Annals of Neurology
, vol.63
, Issue.2
, pp. 204-212
-
-
Josephs, K.A.1
Whitwell, J.L.2
Ahmed, Z.3
Shiung, M.M.4
Weigand, S.D.5
Knopman, D.S.6
Boeve, B.F.7
Parisi, J.E.8
Petersen, R.C.9
Dickson, D.W.10
Jack Jr., C.R.11
-
139
-
-
77953185697
-
Higher soluble amyloid-β concentration in frontal cortex of young adults than in normal elderly or alzheimer's disease
-
van Helmond Z, Miners JS, Kehoe PG, Love S. Higher soluble amyloid-β concentration in frontal cortex of young adults than in normal elderly or alzheimer's disease. Brain Pathol 2010:9999.
-
(2010)
Brain Pathol
, pp. 9999
-
-
Van Helmond, Z.1
Miners, J.S.2
Kehoe, P.G.3
Love, S.4
-
140
-
-
77952547828
-
Vascular risk factor detection and control may prevent alzheimer's disease
-
de la Torre JC. Vascular risk factor detection and control may prevent alzheimer's disease. Ageing Res Rev 2010;9:218-25.
-
(2010)
Ageing Res Rev
, vol.9
, pp. 218-225
-
-
De La Torre, J.C.1
-
141
-
-
33845505233
-
Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expession
-
DOI 10.1073/pnas.0606298103
-
Sun X, He G, Qing H, Zhou W, Dobie F, Cai F, Staufenbiel M, Huang LE, Song W. Hypoxia facilitates alzheimer's disease pathogenesis by up-regulating bace1 gene expression. Proc Natl Acad Sci U S A 2006;103:18727-32. (Pubitemid 44913478)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.49
, pp. 18727-18732
-
-
Sun, X.1
He, G.2
Qing, H.3
Zhou, W.4
Dobie, F.5
Cai, F.6
Staufenbiel, M.7
Huang, L.E.8
Song, W.9
-
142
-
-
34249727115
-
Hypoxia-inducible factor 1α (HIF-1α)-mediated hypoxia increases BACE1 expression and β-amyloid generation
-
DOI 10.1074/jbc.M608856200
-
Zhang X, Zhou K, Wang RS, Cui JK, Lipton SA, Liao FF, Xu HX, Zhang YW. Hypoxia-inducible factor 1 α (hif-1 α)-mediated hypoxia increases bace1 expression and β-amyloid generation. J Biol Chem 2007;282:10873-80. (Pubitemid 47100783)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.15
, pp. 10873-10880
-
-
Zhang, X.1
Zhou, K.2
Wang, R.3
Cui, J.4
Lipton, S.A.5
Liao, F.-F.6
Xu, H.7
Zhang, Y.-W.8
-
143
-
-
0032960553
-
Cerebral hypoperfusion yields capillary damage in the hippocampal CA1 area that correlates with spatial memory impairment
-
DOI 10.1016/S0306-4522(98)00659-9, PII S0306452298006599
-
De Jong GI, Farkas E, Stienstra CM, Plass JRM, Keijser JN, de la Torre JC, Luiten PGM. Cerebral hypoperfusion yields capillary damage in the hippocampal ca1 area that correlates with spatial memory impairment. Neuroscience 1999;91:203-10. (Pubitemid 29170459)
-
(1999)
Neuroscience
, vol.91
, Issue.1
, pp. 203-210
-
-
De Jong, G.I.1
Farkas, E.2
Stienstra, C.M.3
Plass, J.R.M.4
Keijser, J.N.5
De La, T.J.C.6
Luiten, P.G.M.7
-
144
-
-
0141483381
-
Early intervention is key to successful management of alzheimer disease
-
DeKosky S. Early intervention is key to successful management of alzheimer disease. Alzheimer Dis Assoc Disord 2003;17:S99-104.
-
(2003)
Alzheimer Dis Assoc Disord
, vol.17
-
-
DeKosky, S.1
-
145
-
-
23844554898
-
Molecular Neuroimaging in Alzheimer's Disease
-
DOI 10.1602/neurorx.1.2.206, PII S1545534306700360, Biomarkers and Surrogates
-
Jagust W. Molecular neuroimaging in alzheimer's disease. NeuroRx 2004;1:206-12. (Pubitemid 46589352)
-
(2004)
NeuroRx
, vol.1
, Issue.2
, pp. 206-212
-
-
Jagust, W.1
-
146
-
-
48849094089
-
Endothelin: 20 years from discovery to therapy
-
Barton M. Yanagisawa M. Endothelin: 20 years from discovery to therapy. Can J Physiol Pharmacol 2008;86:485-98.
-
(2008)
Can J Physiol Pharmacol
, vol.86
, pp. 485-498
-
-
Barton, M.1
Yanagisawa, M.2
-
147
-
-
17344373615
-
Hemodynamic and coronary effects of the endothelin antagonist bosentan in patients with coronary artery disease
-
Wenzel RR, Fleisch M, Shaw S, Noll G, Kaufmann U, Schmitt R, Jones CR, Clozel M, Meier B, Luscher TF. Hemodynamic and coronary effects of the endothelin antagonist bosentan in patients with coronary artery disease. Circulation 1998;98:2235-40. (Pubitemid 28533840)
-
(1998)
Circulation
, vol.98
, Issue.21
, pp. 2235-2240
-
-
Wenzel, R.R.1
Fleisch, M.2
Shaw, S.3
Noll, G.4
Kaufmann, U.5
Schmitt, R.6
Jones, C.R.7
Clozel, M.8
Meier, B.9
Luscher, T.F.10
-
148
-
-
76749085229
-
Endothelin, hypertension and chronic kidney disease: New insights
-
Kohan DE. Endothelin, hypertension and chronic kidney disease: new insights. Curr Opin Nephrol Hypertens 2010;19:134-9.
-
(2010)
Curr Opin Nephrol Hypertens
, vol.19
, pp. 134-139
-
-
Kohan, D.E.1
-
149
-
-
0034720820
-
Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure
-
Givertz MM, Colucci WS, LeJemtel TH, Gottlieb SS, Hare JM, Slawsky MT, Leier CV, Loh E, Nicklas JM, Lewis BE. Study I. Acute endothelin a receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure. Circulation 2000;101:2922-7. (Pubitemid 30415882)
-
(2000)
Circulation
, vol.101
, Issue.25
, pp. 2922-2927
-
-
Givertz, M.M.1
Colucci, W.S.2
LeJemtel, T.H.3
Gottlieb, S.S.4
Hare, J.M.5
Slawsky, M.T.6
Leier, C.V.7
Loh, E.8
Nicklas, J.M.9
Lewis, B.E.10
-
150
-
-
0028934893
-
Endothelin antagonists improve renal-function in spontaneously hypertensive rats
-
Kato T, Kassab S, Wilkins FC, Kirchner KA, Keiser J, Granger JP. Endothelin antagonists improve renal-function in spontaneously hypertensive rats. Hypertension 1995;25:883-7.
-
(1995)
Hypertension
, vol.25
, pp. 883-887
-
-
Kato, T.1
Kassab, S.2
Wilkins, F.C.3
Kirchner, K.A.4
Keiser, J.5
Granger, J.P.6
-
151
-
-
0027764533
-
Antihypertensive effects of the endothelin receptor antagonist bq-123 in conscious spontaneously hypertensive rats
-
Ohlstein EH, Douglas SA, Ezekiel M, Gellai M. Antihypertensive effects of the endothelin receptor antagonist bq-123 in conscious spontaneously hypertensive rats. J Cardiovasc Pharmacol 1993;22:S321-4.
-
(1993)
J Cardiovasc Pharmacol
, vol.22
-
-
Ohlstein, E.H.1
Douglas, S.A.2
Ezekiel, M.3
Gellai, M.4
-
152
-
-
0034713874
-
Hemodynamic effects of bosentan, an endothelin receptor antagonist, in patients with pulmonary hypertension
-
Williamson DJ, Wallman LL, Jones R, Keogh AM, Scroope F, Penny R, Weber
-
(2000)
Circulation
, vol.102
, Issue.4
, pp. 411-418
-
-
Williamson, D.J.1
Wallman, L.L.2
Jones, R.3
Keogh, A.M.4
Scroope, F.5
Penny, R.6
Weber, C.7
Macdonald, P.S.8
-
153
-
-
0029564275
-
Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats
-
Chen SJ, Chen YF, Meng QC, Durand J, Dicarlo VS, Oparil S. Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats. J Appl Physiol 1995;79:2122-31. (Pubitemid 26010587)
-
(1995)
Journal of Applied Physiology
, vol.79
, Issue.6
, pp. 2122-2131
-
-
Chen, S.-J.1
Chen, Y.-F.2
Qing, C.M.3
Durand, J.4
Dicarlo, V.S.5
Oparil, S.6
-
154
-
-
45249119855
-
Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): A double-blind, randomised controlled trial
-
DOI 10.1016/S0140-6736(08)60919-8, PII S0140673608609198
-
Galie N, Rubin L, Hoeper M, Jansa P, Al-Hiti H, Meyer G, Chiossi E, Kusic-Pajic A, Simonneau G. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (early study): a double-blind, randomised controlled trial [see comment]. Lancet 2008;371:2093-100. (Pubitemid 351902178)
-
(2008)
The Lancet
, vol.371
, Issue.9630
, pp. 2093-2100
-
-
Galie, N.1
Rubin, L.2
Hoeper, M.3
Jansa, P.4
Al-Hiti, H.5
Meyer, G.6
Chiossi, E.7
Kusic-Pajic, A.8
Simonneau, G.9
-
155
-
-
0034137623
-
Endothelial dysfunction and atherosclerosis: Endothelin receptor antagonists as novel therapeutics
-
Barton M. Endothelial dysfunction and atherosclerosis: endothelin receptor antagonists as novel therapeutics. Curr Hypertens Rep 2000;2:84-91.
-
(2000)
Curr Hypertens Rep
, vol.2
, pp. 84-91
-
-
Barton, M.1
-
156
-
-
0032478272
-
Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade
-
Verhaar MC, Strachan FE, Newby DE, Cruden NL, Koomans HA, Rabelink TJ, Webb DJ. Endothelin-a receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-b receptor blockade. Circulation 1998;97:752-6. (Pubitemid 28135337)
-
(1998)
Circulation
, vol.97
, Issue.8
, pp. 752-756
-
-
Verhaar, M.C.1
Strachan, F.E.2
Newby, D.E.3
Cruden, N.L.4
Koomans, H.A.5
Rabelink, T.J.6
Webb, D.J.7
-
157
-
-
31844456345
-
Bosentan preserves endothelial function in mice overexpressing APP
-
DOI 10.1016/j.neurobiolaging.2005.02.012, PII S0197458005000990
-
Elesber AA, Bonetti PO, Woodrum JE, Zhu XY, Lerman LO, Younkin SG, Lerman A. Bosentan preserves endothelial function in mice overexpressing app. Neurobiol Aging 2006;27:446-50. (Pubitemid 43185330)
-
(2006)
Neurobiology of Aging
, vol.27
, Issue.3
, pp. 446-450
-
-
Elesber, A.A.1
Bonetti, P.O.2
Woodrum, J.E.3
Zhu, X.-Y.4
Lerman, L.O.5
Younkin, S.G.6
Lerman, A.7
-
158
-
-
68849115556
-
The science of endothelin-1 and endothelin receptor antagonists in the management of pulmonary arterial hypertension: Current understanding and future studies
-
Davie NJ, Schermuly RT, Weissmann N, Grimminger F, Ghofrani HA. The science of endothelin-1 and endothelin receptor antagonists in the management of pulmonary arterial hypertension: current understanding and future studies. Eur J Clin Invest 2009;39:38-49.
-
(2009)
Eur J Clin Invest
, vol.39
, pp. 38-49
-
-
Davie, N.J.1
Schermuly, R.T.2
Weissmann, N.3
Grimminger, F.4
Ghofrani, H.A.5
-
159
-
-
67349093525
-
Clearance mechanisms of alzheimer's amyloid-β peptide: Implications for therapeutic design and diagnostic tests
-
Bates KA, Verdile G, Li QX, Ames D, Hudson P, Masters CL, Martins RN. Clearance mechanisms of alzheimer's amyloid-β peptide: implications for therapeutic design and diagnostic tests. Mol Psychiatry 2009;14:469-86.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 469-486
-
-
Bates, K.A.1
Verdile, G.2
Li, Q.X.3
Ames, D.4
Hudson, P.5
Masters, C.L.6
Martins, R.N.7
-
160
-
-
42149125510
-
Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease
-
DOI 10.2174/156720508783954785
-
Nalivaeva NN, Fisk LR, Belyaev ND, Turner AJ. Amyloid-degrading enzymes as therapeutic targets in alzheimer's disease. Curr Alzheimer Res 2008;5:212-24. (Pubitemid 351536346)
-
(2008)
Current Alzheimer Research
, vol.5
, Issue.2
, pp. 212-224
-
-
Nalivaeva, N.N.1
Fisk, L.R.2
Belyaev, N.D.3
Turner, A.J.4
-
161
-
-
50549103941
-
Adeno-associated viral (aav) serotype 5 vector mediated gene delivery of endothelin-converting enzyme reduces a beta deposits in app + ps1 transgenic mice
-
Carty NC, Nash K, Lee D, Mercer M, Gottschall PE, Meyers C, Muzyczka N, Gordon MN, Morgan D. Adeno-associated viral (aav) serotype 5 vector mediated gene delivery of endothelin-converting enzyme reduces a beta deposits in app + ps1 transgenic mice. Mol Ther 2008;16:1580-6.
-
(2008)
Mol Ther
, vol.16
, pp. 1580-1586
-
-
Carty, N.C.1
Nash, K.2
Lee, D.3
Mercer, M.4
Gottschall, P.E.5
Meyers, C.6
Muzyczka, N.7
Gordon, M.N.8
Morgan, D.9
-
162
-
-
77953949978
-
Gene therapy in alzheimer's disease - Potential for disease modification
-
Nilsson P, Iwata N, Muramatsu S-i, Tjernberg LO, Winblad B, Saido TC. Gene therapy in alzheimer's disease - potential for disease modification. J Cell Mol Med 2010;14:741-57.
-
(2010)
J Cell Mol Med
, vol.14
, pp. 741-757
-
-
Nilsson, P.1
Iwata, N.2
Muramatsu, S.-I.3
Tjernberg, L.O.4
Winblad, B.5
Saido, T.C.6
-
163
-
-
0030848729
-
Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor protein
-
Zhang FY, Eckman C, Younkin S, Hsiao KK, Iadecola C. Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor protein. J Neurosci 1997;17:7655-61. (Pubitemid 27426204)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.20
, pp. 7655-7661
-
-
Zhang, F.1
Eckman, C.2
Younkin, S.3
Hsiao, K.K.4
Iadecola, C.5
-
164
-
-
0036327648
-
Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease
-
DOI 10.1161/01.STR.0000024523.82311.77
-
Suter OC, Sunthorn T, Kraftsik R, Straubel J, Darekar P, Khalili K, Miklossy J. Cerebral hypoperfusion generates cortical watershed microinfarcts in alzheimer disease. Stroke 2002;33:1986-92. (Pubitemid 34840055)
-
(2002)
Stroke
, vol.33
, Issue.8
, pp. 1986-1992
-
-
Suter, O.-C.1
Sunthorn, T.2
Kraftsik, R.3
Straubel, J.4
Darekar, P.5
Khalili, K.6
Miklossy, J.7
-
165
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 2001;81:741-66. (Pubitemid 32267077)
-
(2001)
Physiological Reviews
, vol.81
, Issue.2
, pp. 741-766
-
-
Selkoe, D.J.1
-
166
-
-
58149107332
-
Harvey cushing and the regulation of blood pressure in giraffe, rat and man: Introducing 'cushing's mechanism'
-
Paton JFR, Dickinson CJ, Mitchell G. Harvey cushing and the regulation of blood pressure in giraffe, rat and man: introducing 'cushing's mechanism'. Exp Physiol 2009;94:11-7.
-
(2009)
Exp Physiol
, vol.94
, pp. 11-17
-
-
Paton, J.F.R.1
Dickinson, C.J.2
Mitchell, G.3
-
167
-
-
34250193311
-
Vascular-brain signaling in hypertension: Role of angiotensin II and nitric oxide
-
DOI 10.1007/s11906-007-0043-1
-
Paton JFR, Waki H, Abdala APL, Dickinson J, Kasparov S. Vascular-brain signaling in hypertension: role of angiotensin ii and nitric oxide. Curr Hypertens Rep 2007;9:242-7. (Pubitemid 46894818)
-
(2007)
Current Hypertension Reports
, vol.9
, Issue.3
, pp. 242-247
-
-
Paton, J.F.R.1
Waki, H.2
Abdala, A.P.L.3
Dickinson, J.4
Kasparov, S.5
|