Neurofibrillary pathology - Correlation with hippocampal formation atrophy in Alzheimer disease

Neurobiology of Aging

Volumn 17, Issue 6, 1996, Pages 909-919

  Bobinski, Maciej ^a   Wegiel, Jerzy ^a   Wisniewski, Henryk M ^a   Tarnawski, Michal ^a   Bobinski, Margaret ^a   Reisberg, Barry ^b   De Leon, Mony J ^b   Miller, Douglas C ^b  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Alzheimer disease; amyloid deposits; hippocampal formation; morphometry; neurofibrillary pathology; neuronal loss

Indexed keywords

AGED; ALZHEIMER DISEASE; AMYLOID NEUROPATHY; ARTICLE; CASE REPORT; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MORPHOMETRICS; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL;

EID: 0030294729     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(96)00160-1     Document Type: Article

References (60)

1. 1. Amaral, D. G.; Insausti, R. Hippocampal formation. In: Paxinos, G., ed. The human nervous system. San Diego: Academic Press, Inc.; 1990:711-755.
2. 2. Auer, S. R.; Sclan, S. G.; Yaffee, R. A.; Reisberg, B. The neglected half of Alzheimer disease: Cognitive and functional concomitants of severe dementia. J. Am. Geriatr. Soc. 42:1266-1272; 1994.
3. 3. Ball, M. J. Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia. Acta Neuropathol. 37:111-118; 1977.
4. 4. Ball, M. J. Topographic distribution of neurofibrillary tangles and granulovacuolar degeneration in hippocampal cortex of aging and demented patients. A quantitative study. Acta Neuropathol. 42:73-80; 1978.
5. 5. Ball, M. J.; Hachinski, V.; Fox, A.; Kirshen, A. J.; Fisman, M.; Blume, W.; Kral, V. A.; Fox, H. A new definition of Alzheimer's disease: A hippocampal dementia. Lancet i:14-16; 1985.
6. 6. Ball, M. J.; Nuttall, K. Topography of neurofibrillary tangles and granulovacuoles in hippocampi of patients with Down's syndrome: Quantitative comparison with normal ageing and Alzheimer's disease. Neuropathol. Appl. Neurobiol. 7:13-20; 1981.
7. 7. Bancher, C.; Brunner, C.; Lassmann, H.; Budka, H.; Jellinger, K.; Wiche, G.; Seitelberger, F.; Grundke-Iqbal, I.; Iqbal, K.; Wisniewski, H. M. Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res 477:90-99; 1989.
8. 8. Bobinski, M.; Wegiel, J.; Wisniewski, H. M.; Tarnawski, M.; Reisberg, B.; Mlodzik, B.; De Leon, M. J.; Miller, D. C. Atrophy of hippocampal formation subdivisions correlates with stage and duration of Alzheimer disease. Dementia 6:205-210; 1995.
9. 9. Bouras, C.; Hof, P. R.; Giannakopoulos, P.; Michel, J. P.; Morrison, J. H. Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: A quantitative evaluation of a one-year autopsy population from a geriatric hospital. Cereb. Cortex 4:138-150; 1994.
10. 10. Braak, H. Architectonics of the human telencephalic cortex. Berlin: Springer Verlag; 1980.
11. 11. Braak, H. On areas of transition between entorhinal allocortex and temporal isocortex in the human brain. Normal morphology and lamina-specific pathology in Alzheimer's disease. Acta Neuropathol. 68:325-332; 1985.
12. 12. Braak, H.; Braak, E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 82:239-259; 1991.
13. 13. Braak, H.; Braak, E. Pathology of Alzheimer's disease. In: Calne, D. B., ed. Neurodegenerative diseases. Philadelphia: W. B. Saunders; 1994:585-613.
14. 14. Brady, D. R.; Mufson, E. J. Alz-50 immunoreactive neuropil differentiates hippocampal complex subfields in Alzheimer's disease. J. Comp. Neurol. 305:489-507; 1991.
15. 15. Brun, A.; Englund, E. Regional pattern of degeneration in Alzheimer's disease: Neuronal loss and histopathological grading. Histopathology 5:549-564; 1981.
16. 16. Coleman, P. D.; Flood, D. G. Neuron numbers and dendritic extent in normal aging and Alzheimer's disease. Neurobiol. Aging 8:521-545; 1987.
17. 17. Convit, A.; De Leon, M. J.; Tarshish, C.; De Santi, S.; Kluger, A.; Rusinek, H.; George, A. E. Hippocampal volume losses in minimally impaired elderly [letter]. Lancet 345:266; 1995.
18. 18. Davies, D. C.; Horwood, N.; Isaacs, S. L.; Mann, D. M. A. The effect of age and Alzheimer's disease on pyramidal neuron density in the individual fields of the hippocampal formation. Acta Neuropathol. 83:510-517; 1992.
19. 19. de Leon, M. J.; Golomb, J.; George, A. E.; Convit, A.; Tarshish, C. Y.; McRae, T.; De Santi, S.; Smith, G.; Ferris, S. H.; Noz, M. The radiologic prediction of Alzheimer disease: The atrophic hippocampal formation. AJNR 14:897-906; 1993.
20. 20. DeHoff, R. T. Sampling of material and statistical analysis in quantitative stereology. In: Elias, H., ed. Stereology: Proceedings of the second international congress for stereology. New York: Springer Verlag; 1967:119.
21. 21. Doebler, J. A.; Markesbery, W. R.; Anthony, A.; Rhoads, R. E. Neuronal RNA in relation to neuronal loss and neurofibrillary pathology in the hippocampus in Alzheimer's disease. J. Neuropathol. Exp. Neurol. 46:28-39; 1987.
22. 22. Duvernoy, H. M. The human hippocampus. Munchen: J. F. Bergmann Verlag; 1988.
23. 23. Floderus, S. Untersuchungen über den Bau der menschlichen Hypophyse mit besonderer Berucksichtigung der quantitativen mikromorphologischen Verhaltnisse. Acta Pathol. Microbiol. Scand. Suppl. 53; 1944.
24. 24. Franssen, E. H.; Kluger, A.; Torossian, C. L.; Reisberg, B. The neurologic syndrome of severe Alzheimer's disease. Arch. Neurol. 50: 1029-1039; 1993.
25. 25. Gibson, P. H. Form and distribution of senile plaques seen in silver impregnated sections in the brains of intellectually normal elderly people and people with Alzheimer-type dementia. Neuropathol. Appl. Neurobiol. 9:379-389; 1983.
26. 26. Goedert, M.; Spillantini, M. G.; Jakes, R.; Rutherford, D.; Crowther, R. A. Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3:519-526; 1989.
27. 27. Golomb, J.; De Leon, M. J.; Kluger, A.; George, A. E.; Tarshish, C.; Ferris, S. H. Hippocampal atrophy in normal aging. An association with recent memory impairment. Arch. Neurol. 50:967-973; 1993.
28. 28. Grundke-Iqbal, I.; Iqbal, K.; Tung, Y.-C.; Quinlan, M.; Wisniewski, H. M.; Binder, L. I. Abnormal phosphorylation of the microtubule-associated protein τ (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA 83:4913-4917; 1986.
29. 29. Gundersen, H. J.; Bagger, P.; Bendtsen, T. F.; Evans, S. M.; Korbo, L.; Marcussen, N.; Moller, A.; Nielsen, K.; Nyengaard, J. R.; Pakkenberg, B. The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathologic research and diagnosis. APMIS 96:857-881; 1988.
30. 30. Hardy, J. A.; Higgins, G. A. The amyloid cascade hypothesis. Science 256:184-185; 1992
31. 31. Haug, H. Stereological methods in the analysis of neuronal parameters in the central nervous system. J. Microsc. 95:165-180; 1971.
32. 32. Hirano, A.; Malamud, N.; Elizan, T. S.; Kurland, L. T. Amyotrophic lateral sclerosis and parkinsonism-dementia complex of Guam. Arch. Neurol. 15:35-51; 1966.
33. 33. Hirano, A.; Malamud, N.; Kurland, L. T. Parkinsonism-dementia complex, an endemic disease on the island of Guam. II. Pathological features. Brain 84:662-679; 1961.
34. 34. Hyman, B. T.; Van Hoesen, G. W.; Damasio, A. R.; Barnes, C. L. Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation. Science 225:1168-1170; 1984.
35. 35. Hyman, B. T.; Van Hoesen, G. W.; Kromer, L. J.; Damasio, A. R. Perforant pathway changes and the memory impairment of Alzheimer's disease. Ann. Neurol. 20:472-481; 1986.
36. 36. Jack, C. R.; Petersen, R. C.; O'Brien, P. C.; Tangalos, E. G. MR-based hippocampal volumetry in the diagnosis of Alzheimer's disease. Neurology 42:183-188; 1992.
37. 37. Kesslak, J. P.; Nalcioglu, O.; Cotman, C. W. Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimer's disease. Neurology 41:51-54; 1991.
38. 38. Khachaturian, Z. S. Diagnosis of Alzheimer's disease. Arch. Neurol. 42:1097-1105; 1985.
39. 39. Kitamoto, T.; Ogomori, K.; Tateishi, J.; Prusiner, S. B. Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. Lab. Invest. 57:230-232; 1987.
40. 40. Lorente de No, R. Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system. J. Psychol. Neurol. 46:113-177; 1934.
41. 41. Mackenzie, I. R. Senile plaques do not progressively accumulate with normal aging. Acta Neuropathol. 87:520-525; 1994.
42. 42. Mani, R. B.; Lohr, J. B.; Jeste, D. V. Hippocampal pyramidal cells and aging in the human: A quantitative study of neuronal loss in sectors CA1 to CA4. Exp. Neurol. 94:29-40; 1986.
43. 43. Mann, D. M. A.; Yates, P. O.; Marcyniuk, B. Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer's type and Down's syndrome in middle age. J. Neurol. Sci. 69:139-159; 1985.
44. 44. Ohm, T. G.; Müller, H.; Braak, H.; Bohl, J. Close-meshed prevalence rates of different stages as a tool to uncover the rate of Alzheimer's disease-related neurofibrillary changes. Neuroscience 64:209-217; 1995.
45. 45. Pakkenberg, B.; Gundersen, H. J. New stereological method for obtaining unbiased and efficient estimates of total nerve cell number in human brain areas. Exemplified by the mediodorsal thalamic nucleus in schizophrenics. APMIS 97:677-681; 1989.
46. 46. Pakkenberg, B.; Gundersen, H. J. G. Total number of neurons and glial cells in human brain nuclei estimated by the disector and the fractionator. J. Microsc. 150:1-20; 1988.
47. 47. Reisberg, B. Functional assessment staging (FAST). Psychopharmacol. Bull. 24:653-659; 1988.
48. 48. Reisberg, B.; Ferris, S. H.; De Leon, M. J.; Crook, T. The global deterioration scale for assessment of primary degenerative dementia. Am. J. Psychiatry 139:1136-1139; 1982.
49. 49. Rosene, D. L.; Van Hoesen, G. W. The hippocampal formation of the primate brain. In: Jones, E. G.; Peters, A., eds. Cerebral cortex, vol. 6. Further aspects of cortical function, including hippocampus. New York: Plenum Press; 1987:345-456.
50. 50. Roses, A. D. Apolipoprotein E affects the rate of Alzheimer disease expression: β-Amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease. J. Neuropathol. Exp. Neurol. 53:429-437; 1994.
51. 51. Seab, J. P.; Jagust, W. J.; Wong, S. T.; Roos, M.S.; Reed, B. R.; Budinger, T. F. Quantitative NMR measurements of hippocampal atrophy in Alzheimer's disease. Magn. Reson. Med. 8:200-208; 1988.
52. 52. Silverman, W.; Popovitch, E.; Schupf, N.; Zigman, W. B.; Rabe, A.; Sersen, E.; Wisniewski, H. M. Alzheimer neuropathology in mentally retarded adults: Statistical independence of regional amyloid plaque and neurofibrillary tangle densities. Acta Neuropathol. 85:260-266; 1993.
53. 53. Souren, L. E. M.; Franssen, E. H.; Reisberg, B. Contractures and loss of function in patients with Alzheimer's disease. J. Am. Geriatr. Soc. 43:650-655; 1995.
54. 54. Sterio, D. C. The unbiased estimation of number and sizes of arbitrary particles using the disector. J. Microsc. 134:127-136; 1984.
55. 55. Swaab, D. F.; Uylings, H. B. M. Density measures: Parameters to avoid. Neurobiol. Aging 8:574-576; 1987.
56. 56. West, M. J.; Coleman, P. D.; Flood, D. G.; Troncoso, J. C. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 344:769-772; 1994.
57. 57. West, M. J.; Gundersen, H. J. G. Unbiased stereological estimation of the number of neurons in the human hippocampus. J. Comp. Neurol. 296:1-22; 1990.
58. 58. Wisniewski, H. M.; Constantinidis, J.; Wegiel, J.; Bobinski, M.; Tarnawski, M. Neurofibrillary pathology in brains of elderly schizophrenics treated with neuroleptics. Alzheimer Disease Assoc. Dis. 8:211-227; 1994.
59. 59. Wisniewski, H. M.; Dymecki, J.; Wegiel, J.; Kulczycki, J.; Schmidt-Sidor, B.; Grundke-Iqbal, I.; Strojny, P. Neurofibrillary pathology in subacute sclerosing panencephalitis. Dementia 2:133-141; 1991.
60. 60. Wisniewski, H. M.; Wegiel, J. Do neurofibrillary tangles initiate plaque formation or is it β-amyloidosis that leads to NFT pathology? Neurobiol. Aging 16:341-343; 1995.