Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease

Neurology

Volumn 56, Issue 1, 2001, Pages 127-129

  Masliah, E ^a,b   Mallory, M ^a   Alford, M ^a   DeTeresa, R ^a   Hansen, L A ^a,b   McKeel Jr , D W ^c   Morris, J C ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROMODULIN; SYNAPTOPHYSIN; SYNAPTOTAGMIN;

ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FRONTAL CORTEX; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0035830408     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.56.1.127     Document Type: Article

References (10)

1. Physical basis of cognitive alterations in Alzheimer disease: Synapse loss is the major correlate of cognitive impairment
2. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
3. Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimer's and Parkinson's disease patients
4. Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity
5. Synaptic and neuritic alterations during the progression of Alzheimer's disease
6. Synaptotagmin, a synaptic vesicle protein, is present in human cerebrospinal fluid: A new biochemical marker for synaptic in Alzheimer disease?
7. A radioimmunoassay to monitor synaptic activity in hippocampal neurons in vitro
8. Clinical dementia rating (CDR) training and reliability protocol: The Alzheimer's Disease Cooperative Study Unit experience
9. The synaptic protein NACP is abnormally expressed during the progression of Alzheimer's disease
10. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease