메뉴 건너뛰기




Volumn 59, Issue 4, 2006, Pages 673-681

Brain imaging evidence of preclinical Alzheimer's disease in normal aging

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

EID: 33645788000     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.20799     Document Type: Article
Times cited : (189)

References (51)
  • 1
    • 0021145680 scopus 로고
    • Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation
    • Hyman BT, Van Hoesen GW, Damasio AR, Barnes CL. Alzheimer's disease: cell-specific pathology isolates the hippocampal formation. Science 1984;225:1168-1170.
    • (1984) Science , vol.225 , pp. 1168-1170
    • Hyman, B.T.1    Van Hoesen, G.W.2    Damasio, A.R.3    Barnes, C.L.4
  • 2
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991;82:239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 3
    • 0343416812 scopus 로고    scopus 로고
    • Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease
    • Jack CR, Petersen RC, Xu UC, et al. Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology 1997;49:786-794.
    • (1997) Neurology , vol.49 , pp. 786-794
    • Jack, C.R.1    Petersen, R.C.2    Xu, U.C.3
  • 4
    • 0035173606 scopus 로고    scopus 로고
    • MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease
    • Dickerson BC, Goncharova I, Sullivan MP, et al. MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease. Neurobiol Aging 2001;22:747-754.
    • (2001) Neurobiol Aging , vol.22 , pp. 747-754
    • Dickerson, B.C.1    Goncharova, I.2    Sullivan, M.P.3
  • 5
    • 0030874251 scopus 로고    scopus 로고
    • Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease
    • Minoshima S, Giordani B, Berent S, et al. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Ann Neurol 1997;42:85-94.
    • (1997) Ann Neurol , vol.42 , pp. 85-94
    • Minoshima, S.1    Giordani, B.2    Berent, S.3
  • 6
    • 0035824167 scopus 로고    scopus 로고
    • Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome
    • Silverman DH, Small GW, Chang CY, et al. Positron emission tomography in evaluation of dementia: regional brain metabolism and long-term outcome. JAMA 2001;286:2120-2127.
    • (2001) JAMA , vol.286 , pp. 2120-2127
    • Silverman, D.H.1    Small, G.W.2    Chang, C.Y.3
  • 7
    • 0032988610 scopus 로고    scopus 로고
    • Mild cognitive impairment: Clinical characterization and outcome
    • Petersen RC, Smith GE, Waring SC, et al. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 1999;56:303-308.
    • (1999) Arch Neurol , vol.56 , pp. 303-308
    • Petersen, R.C.1    Smith, G.E.2    Waring, S.C.3
  • 8
    • 0344889207 scopus 로고    scopus 로고
    • Prediction of AD wich MRI-based hippocampal volume in mild cognitive impairment
    • Jack CR, Petersen RC, Xu YC, et al. Prediction of AD wich MRI-based hippocampal volume in mild cognitive impairment. Neurology 1999;52:1397-1403.
    • (1999) Neurology , vol.52 , pp. 1397-1403
    • Jack, C.R.1    Petersen, R.C.2    Xu, Y.C.3
  • 9
    • 0034127931 scopus 로고    scopus 로고
    • Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease
    • Killiany RJ, Gomez-Isla T, Moss M, et al. Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease. Ann Neurol 2000;47:430-439.
    • (2000) Ann Neurol , vol.47 , pp. 430-439
    • Killiany, R.J.1    Gomez-Isla, T.2    Moss, M.3
  • 10
    • 3142539896 scopus 로고    scopus 로고
    • Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairment
    • Korf ESC, Wahlund LO, Visser PJ, Scheltens P. Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairment. Neurology 2004;63:94-100.
    • (2004) Neurology , vol.63 , pp. 94-100
    • Korf, E.S.C.1    Wahlund, L.O.2    Visser, P.J.3    Scheltens, P.4
  • 11
    • 4143148346 scopus 로고    scopus 로고
    • MRI-derived entorhinal volume is a good predictor of conversion from MCI to AD
    • deToledo-Morrell L, Stoub TR, Bulgakova M, et al. MRI-derived entorhinal volume is a good predictor of conversion from MCI to AD. Neurobiol Aging 2004;25:1197-1203.
    • (2004) Neurobiol Aging , vol.25 , pp. 1197-1203
    • Toledo-Morrell, L.1    Stoub, T.R.2    Bulgakova, M.3
  • 12
    • 0035953137 scopus 로고    scopus 로고
    • Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment
    • Arnaiz E, Jelic V, Almkvist O, et al. Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment. Neuroreport 2001;12:851-855.
    • (2001) Neuroreport , vol.12 , pp. 851-855
    • Arnaiz, E.1    Jelic, V.2    Almkvist, O.3
  • 13
    • 0037461347 scopus 로고    scopus 로고
    • Mild cognitive impairment: Can FDG-PET predict who is to rapidly convert to Alzheimer's disease?
    • Chetelat G, Desgranges B, De La Sayette V, et al. Mild cognitive impairment: can FDG-PET predict who is to rapidly convert to Alzheimer's disease? Neurology 2003;60:1374-1377.
    • (2003) Neurology , vol.60 , pp. 1374-1377
    • Chetelat, G.1    Desgranges, B.2    De La Sayette, V.3
  • 14
    • 0029970342 scopus 로고    scopus 로고
    • Preclinical evidence of Alzheimer's disease in persons homozygous for the e4 allele for apolipoprotein E
    • Reiman EM, Caselli RJ, Yun LS, et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the e4 allele for apolipoprotein E. N Engl J Med 1996;334:752-758.
    • (1996) N Engl J Med , vol.334 , pp. 752-758
    • Reiman, E.M.1    Caselli, R.J.2    Yun, L.S.3
  • 15
    • 12944259210 scopus 로고    scopus 로고
    • Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
    • Small GW, Ercoli LM, Silverman DH, et al. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A 2000;97:6037-6042.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6037-6042
    • Small, G.W.1    Ercoli, L.M.2    Silverman, D.H.3
  • 16
    • 0347719366 scopus 로고    scopus 로고
    • Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
    • Reiman EM, Chen K, Alexander GE, et al. Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc Natl Acad Sci U S A 2004;101:284-289.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 284-289
    • Reiman, E.M.1    Chen, K.2    Alexander, G.E.3
  • 17
    • 0032989712 scopus 로고    scopus 로고
    • Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
    • Price JL, Morris JC. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann Neurol 1999;45:358-368.
    • (1999) Ann Neurol , vol.45 , pp. 358-368
    • Price, J.L.1    Morris, J.C.2
  • 18
    • 0037318833 scopus 로고    scopus 로고
    • Prevalence of dementia in older Latinos: The influence of type 2 diabetes mellitus, stroke and genetic factors
    • Haan MN, Mungas DM, Gonzalez HM, et al. Prevalence of dementia in older Latinos: the influence of type 2 diabetes mellitus, stroke and genetic factors. J Am Geriatr Soc 2003;51:169-177.
    • (2003) J Am Geriatr Soc , vol.51 , pp. 169-177
    • Haan, M.N.1    Mungas, D.M.2    Gonzalez, H.M.3
  • 19
    • 0023194048 scopus 로고
    • The Modified Mini-Mental State (3MS) examination
    • Teng EL, Chui HC. The Modified Mini-Mental State (3MS) examination. J Clin Psychiatry 1987;48:314-318.
    • (1987) J Clin Psychiatry , vol.48 , pp. 314-318
    • Teng, E.L.1    Chui, H.C.2
  • 20
    • 0033823225 scopus 로고    scopus 로고
    • Development of psychometrically matched English and Spanish language neuropsychological tests for older persons
    • Mungas D, Reed BR, Marshall SC, Gonzalez HM. Development of psychometrically matched English and Spanish language neuropsychological tests for older persons. Neuropsychology 2000;14:209-223.
    • (2000) Neuropsychology , vol.14 , pp. 209-223
    • Mungas, D.1    Reed, B.R.2    Marshall, S.C.3    Gonzalez, H.M.4
  • 21
    • 0030945482 scopus 로고    scopus 로고
    • Application of a Spanish version of the "Informant Questionnaire on Cognitive Decline in the Elderly" in the clinical assessment of dementia
    • Del-Ser T, Morales JM, Barquero MS, et al. Application of a Spanish version of the "Informant Questionnaire on Cognitive Decline in the Elderly" in the clinical assessment of dementia. Alzheimer Dis Assoc Disord 1997;11:3-8.
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , pp. 3-8
    • Del-Ser, T.1    Morales, J.M.2    Barquero, M.S.3
  • 22
    • 2942683500 scopus 로고    scopus 로고
    • Correlates of memory function in community-dwelling elderly: The importance of white matter hyperintensities
    • Petkov CI, Wu CC, Eberling JL, et al. Correlates of memory function in community-dwelling elderly: the importance of white matter hyperintensities. J Int Neuropsychol Soc 2004;10:371-381.
    • (2004) J Int Neuropsychol Soc , vol.10 , pp. 371-381
    • Petkov, C.I.1    Wu, C.C.2    Eberling, J.L.3
  • 23
    • 20444423242 scopus 로고    scopus 로고
    • Reduced hippocampal metabolism in MCI and AD: Automated FDG-PET image analysis
    • Mosconi L, Tsui WH, De Sand S, et al. Reduced hippocampal metabolism in MCI and AD: automated FDG-PET image analysis. Neurology 2005;64:1860-1867.
    • (2005) Neurology , vol.64 , pp. 1860-1867
    • Mosconi, L.1    Tsui, W.H.2    De Sand, S.3
  • 24
    • 0031195398 scopus 로고    scopus 로고
    • A methodology for specifying PET VOIs using multi-modality techniques
    • Klein GJ, Teng X, Jagust WJ, et al. A methodology for specifying PET VOIs using multi-modality techniques. IEEE Trans Med Imaging 1997;16:405-415.
    • (1997) IEEE Trans Med Imaging , vol.16 , pp. 405-415
    • Klein, G.J.1    Teng, X.2    Jagust, W.J.3
  • 25
    • 0033034402 scopus 로고    scopus 로고
    • Effects of subcortical cerebral infarction on cortical glucose metabolism and cognitive function
    • Kwan LT, Reed BR, Eberling JL, et al. Effects of subcortical cerebral infarction on cortical glucose metabolism and cognitive function. Arch Neurol. 1999;56:809-814.
    • (1999) Arch Neurol , vol.56 , pp. 809-814
    • Kwan, L.T.1    Reed, B.R.2    Eberling, J.L.3
  • 26
    • 0025287084 scopus 로고
    • Correction of PET data for partial volume effects in human cerebral cortex by MR imaging
    • Meltzer CC, Leal JP, Mayberg HS, et al. Correction of PET data for partial volume effects in human cerebral cortex by MR imaging. J Comput Assist Tomogr 1990;14:561-570.
    • (1990) J Comput Assist Tomogr , vol.14 , pp. 561-570
    • Meltzer, C.C.1    Leal, J.P.2    Mayberg, H.S.3
  • 27
    • 0034680078 scopus 로고    scopus 로고
    • Patterns of brain activation in people at risk for Alzheimer's disease
    • Bookheimer SY, Strojwas MH, Cohen MS, et al. Patterns of brain activation in people at risk for Alzheimer's disease. N Engl J Med 2000;343:450-456.
    • (2000) N Engl J Med , vol.343 , pp. 450-456
    • Bookheimer, S.Y.1    Strojwas, M.H.2    Cohen, M.S.3
  • 28
    • 3042714810 scopus 로고    scopus 로고
    • Medial temporal lobe function and structure in mild cognitive impairment
    • Dickerson BC, Salat DH, Bates JF, et al. Medial temporal lobe function and structure in mild cognitive impairment. Ann Neurol 2004;56:27-35.
    • (2004) Ann Neurol , vol.56 , pp. 27-35
    • Dickerson, B.C.1    Salat, D.H.2    Bates, J.F.3
  • 29
    • 0037072263 scopus 로고    scopus 로고
    • Brain function and cognition in a community sample of elderly Latinos
    • Jagust WJ, Eberling JL, Wu CC, et al. Brain function and cognition in a community sample of elderly Latinos. Neurology 2002;59:378-383.
    • (2002) Neurology , vol.59 , pp. 378-383
    • Jagust, W.J.1    Eberling, J.L.2    Wu, C.C.3
  • 30
    • 0037072299 scopus 로고    scopus 로고
    • Brain structure and cognition in a community sample of elderly Latinos
    • Wu CC, Mungas D, Petkov CI, et al. Brain structure and cognition in a community sample of elderly Latinos. Neurology 2002;59:383-391.
    • (2002) Neurology , vol.59 , pp. 383-391
    • Wu, C.C.1    Mungas, D.2    Petkov, C.I.3
  • 31
    • 0037066123 scopus 로고    scopus 로고
    • Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia
    • Jack CR, Dickson DW, Parisi JE, et al. Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia. Neurology 2002;58:750-757.
    • (2002) Neurology , vol.58 , pp. 750-757
    • Jack, C.R.1    Dickson, D.W.2    Parisi, J.E.3
  • 32
    • 0030064626 scopus 로고    scopus 로고
    • Comparison of positron emission tomography, cognition and brain volume in Alzhiemer's disease with and without severe abnormalities of white matter
    • DeCarli C, Grady CL, Clark CM, et al. Comparison of positron emission tomography, cognition and brain volume in Alzhiemer's disease with and without severe abnormalities of white matter. J Neurol Neurosurg Psychiatry 1996;60:158-167.
    • (1996) J Neurol Neurosurg Psychiatry , vol.60 , pp. 158-167
    • Decarli, C.1    Grady, C.L.2    Clark, C.M.3
  • 33
    • 0034974107 scopus 로고    scopus 로고
    • Hippocampal formation glucose metabolism and volume losses in MCI and AD
    • De Sand S, de Leon MJ, Rusinek H, et al. Hippocampal formation glucose metabolism and volume losses in MCI and AD. Neurobiol Aging 2001;22:529-539.
    • (2001) Neurobiol Aging , vol.22 , pp. 529-539
    • De Sand, S.1    De Leon, M.J.2    Rusinek, H.3
  • 34
    • 0037007066 scopus 로고    scopus 로고
    • Imaging the progression of Alzheimer pathology through the brain
    • Smith AD. Imaging the progression of Alzheimer pathology through the brain. Proc Natl Acad Sci U S A 2002;99:4135-4137.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4135-4137
    • Smith, A.D.1
  • 35
    • 0034624914 scopus 로고    scopus 로고
    • Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD
    • Xu Y, Jack CR Jr, O'Brien PC, et al. Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD. Neurology 2000;54:1760-1767.
    • (2000) Neurology , vol.54 , pp. 1760-1767
    • Xu, Y.1    Jack Jr., C.R.2    O'Brien, P.C.3
  • 36
    • 0037161240 scopus 로고    scopus 로고
    • MRI measures of entorhinal cortex vs hippocampus in preclinical AD
    • Killiany RJ, Hyman BT, Gomez-Isla T, et al. MRI measures of entorhinal cortex vs hippocampus in preclinical AD. Neurology 2002;58:1188-1196.
    • (2002) Neurology , vol.58 , pp. 1188-1196
    • Killiany, R.J.1    Hyman, B.T.2    Gomez-Isla, T.3
  • 37
    • 0038326624 scopus 로고    scopus 로고
    • Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment
    • Guillozet AL, Weintraub S, Mash DC, Mesulam MM. Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment. Arch Neurol 2003;60:729-736.
    • (2003) Arch Neurol , vol.60 , pp. 729-736
    • Guillozet, A.L.1    Weintraub, S.2    Mash, D.C.3    Mesulam, M.M.4
  • 38
    • 0027320916 scopus 로고
    • Hippocampal atrophy in normal aging: An association with recent memory
    • Golomb J, de Leon MJ, Kluger A, et al. Hippocampal atrophy in normal aging: an association with recent memory. Arch Neurol 1993;50:967-973.
    • (1993) Arch Neurol , vol.50 , pp. 967-973
    • Golomb, J.1    De Leon, M.J.2    Kluger, A.3
  • 39
    • 5344271846 scopus 로고    scopus 로고
    • Size does matter in the long run: Hippocampal and cortical volume predict recall across weeks
    • Walhovd KB, Fjell AM, Reinvang I, et al. Size does matter in the long run: hippocampal and cortical volume predict recall across weeks. Neurology 2004;63:1193-1197.
    • (2004) Neurology , vol.63 , pp. 1193-1197
    • Walhovd, K.B.1    Fjell, A.M.2    Reinvang, I.3
  • 40
    • 0031919190 scopus 로고    scopus 로고
    • Neuroanatomical correlates of cognitive aging: Evidence from structural magnetic resonance imaging
    • Raz N, Gunning-Dixon FM, Head D, et al. Neuroanatomical correlates of cognitive aging: evidence from structural magnetic resonance imaging. Neuropsychology 1998;12:95-114.
    • (1998) Neuropsychology , vol.12 , pp. 95-114
    • Raz, N.1    Gunning-Dixon, F.M.2    Head, D.3
  • 41
    • 2942544464 scopus 로고    scopus 로고
    • Memory and executive function in older adults: Relationships with temporal and prefrontal gray matter volumes and white matter hyperintensities
    • Van Petten C, Plante E, Davidson PS, et al. Memory and executive function in older adults: relationships with temporal and prefrontal gray matter volumes and white matter hyperintensities. Neuropsychologia 2004;42:1313-1335.
    • (2004) Neuropsychologia , vol.42 , pp. 1313-1335
    • Van Petten, C.1    Plante, E.2    Davidson, P.S.3
  • 42
    • 0035845499 scopus 로고    scopus 로고
    • Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET)
    • de Leon MJ, Convit A, Wolf OT, et al. Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET). Proc Natl Acad Sci U S A 2001;98:10966-10971.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10966-10971
    • De Leon, M.J.1    Convit, A.2    Wolf, O.T.3
  • 43
    • 0345446720 scopus 로고    scopus 로고
    • Regional brain atrophy rate predicts future cognitive decline: 6-Year longitudinal MR imaging study of normal aging
    • Rusinek H, De Santi S, Frid D, et al. Regional brain atrophy rate predicts future cognitive decline: 6-year longitudinal MR imaging study of normal aging. Radiology 2003;229:691-696.
    • (2003) Radiology , vol.229 , pp. 691-696
    • Rusinek, H.1    De Santi, S.2    Frid, D.3
  • 44
    • 0742305187 scopus 로고    scopus 로고
    • Shrinkage of the entorhinal cortex over five years predicts memory performance in healthy adults
    • Rodrigue KM, Raz N. Shrinkage of the entorhinal cortex over five years predicts memory performance in healthy adults. J Neurosci 2004;24:956-963.
    • (2004) J Neurosci , vol.24 , pp. 956-963
    • Rodrigue, K.M.1    Raz, N.2
  • 45
    • 10744231722 scopus 로고    scopus 로고
    • Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD
    • Jack CR, Shiung MM, Gunter JL, et al. Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD. Neurology 2004;62:591-600.
    • (2004) Neurology , vol.62 , pp. 591-600
    • Jack, C.R.1    Shiung, M.M.2    Gunter, J.L.3
  • 46
    • 0037452760 scopus 로고    scopus 로고
    • Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly
    • Convit A, Wolf OT, Tarshish C, de Leon MJ. Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly. Proc Natl Acad Sci U S A 2003;100:2019-2022.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2019-2022
    • Convit, A.1    Wolf, O.T.2    Tarshish, C.3    De Leon, M.J.4
  • 47
    • 0042561846 scopus 로고    scopus 로고
    • Impact of diabetes on cognitive function among older Latinos: A population-based cohort study
    • Wu JH, Haan MN, Liang J, et al. Impact of diabetes on cognitive function among older Latinos: a population-based cohort study. J Clin Epidemiol 2003;56:686-693.
    • (2003) J Clin Epidemiol , vol.56 , pp. 686-693
    • Wu, J.H.1    Haan, M.N.2    Liang, J.3
  • 48
    • 8844270812 scopus 로고    scopus 로고
    • Vascular risk factors, incidence of MCI, and rates of progression to dementia
    • Solfrizzi V, Panza F, Colacicco AM, et al. Vascular risk factors, incidence of MCI, and rates of progression to dementia. Neurology 2004;63:1882-1891.
    • (2004) Neurology , vol.63 , pp. 1882-1891
    • Solfrizzi, V.1    Panza, F.2    Colacicco, A.M.3
  • 49
    • 0034646205 scopus 로고    scopus 로고
    • Ten-year incidence of dementia in a rural elderly US community population: The MoVIES Project
    • Ganguli M, Dodge HH, Chen P, et al. Ten-year incidence of dementia in a rural elderly US community population: the MoVIES Project. Neurology 2000;54:1109-1116.
    • (2000) Neurology , vol.54 , pp. 1109-1116
    • Ganguli, M.1    Dodge, H.H.2    Chen, P.3
  • 50
    • 0037154236 scopus 로고    scopus 로고
    • Incidence of AD may decline in the early 90s for men, later for women: The Cache County study
    • Miech RA, Breitner JC, Zandi PP, et al. Incidence of AD may decline in the early 90s for men, later for women: the Cache County study. Neurology 2002;58:209-218.
    • (2002) Neurology , vol.58 , pp. 209-218
    • Miech, R.A.1    Breitner, J.C.2    Zandi, P.P.3
  • 51
    • 0033532737 scopus 로고    scopus 로고
    • The role of APOE e4 in modulating effects of other risk factors for cognitive decline in elderly persons
    • Haan M, Shemanski L, Jagust WJ, et al. The role of APOE e4 in modulating effects of other risk factors for cognitive decline in elderly persons. JAMA 1999;40-46.
    • (1999) JAMA , pp. 40-46
    • Haan, M.1    Shemanski, L.2    Jagust, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.