-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391(6669):806-811.
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
2
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M, Kanapin A, Le Bot N, Moreno S, Sohrmann M, et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 2003, 421(6920):231-237.
-
(2003)
Nature
, vol.421
, Issue.6920
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Poulin, G.4
Durbin, R.5
Gotta, M.6
Kanapin, A.7
Le Bot, N.8
Moreno, S.9
Sohrmann, M.10
-
3
-
-
19344370696
-
Functional dissection of an innate immune response by a genome-wide RNAi screen
-
Foley E, O'Farrell PH. Functional dissection of an innate immune response by a genome-wide RNAi screen. PLoS biology 2004, 2(8):E203.
-
(2004)
PLoS biology
, vol.2
, Issue.8
-
-
Foley, E.1
O'Farrell, P.H.2
-
4
-
-
0842309871
-
Genome-wide RNAi analysis of growth and viability in Drosophila cells
-
Boutros M, Kiger AA, Armknecht S, Kerr K, Hild M, Koch B, Haas SA, Consortium HF, Paro R, Perrimon N. Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 2004, 303(5659):832-835.
-
(2004)
Science
, vol.303
, Issue.5659
, pp. 832-835
-
-
Boutros, M.1
Kiger, A.A.2
Armknecht, S.3
Kerr, K.4
Hild, M.5
Koch, B.6
Haas, S.A.7
Consortium, H.F.8
Paro, R.9
Perrimon, N.10
-
5
-
-
33646033137
-
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
-
Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 2006, 124(6):1283-1298.
-
(2006)
Cell
, vol.124
, Issue.6
, pp. 1283-1298
-
-
Moffat, J.1
Grueneberg, D.A.2
Yang, X.3
Kim, S.Y.4
Kloepfer, A.M.5
Hinkle, G.6
Piqani, B.7
Eisenhaure, T.M.8
Luo, B.9
Grenier, J.K.10
-
6
-
-
27644436787
-
Second-generation shRNA libraries covering the mouse and human genomes
-
Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, et al. Second-generation shRNA libraries covering the mouse and human genomes. Nat Genet 2005, 37(11):1281-1288.
-
(2005)
Nat Genet
, vol.37
, Issue.11
, pp. 1281-1288
-
-
Silva, J.M.1
Li, M.Z.2
Chang, K.3
Ge, W.4
Golding, M.C.5
Rickles, R.J.6
Siolas, D.7
Hu, G.8
Paddison, P.J.9
Schlabach, M.R.10
-
7
-
-
19944367565
-
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
-
Kittler R, Putz G, Pelletier L, Poser I, Heninger AK, Drechsel D, Fischer S, Konstantinova I, Habermann B, Grabner H, et al. An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature 2004, 432(7020):1036-1040.
-
(2004)
Nature
, vol.432
, Issue.7020
, pp. 1036-1040
-
-
Kittler, R.1
Putz, G.2
Pelletier, L.3
Poser, I.4
Heninger, A.K.5
Drechsel, D.6
Fischer, S.7
Konstantinova, I.8
Habermann, B.9
Grabner, H.10
-
8
-
-
77950387346
-
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
-
Neumann B, Walter T, Heriche JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, et al. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature 464(7289):721-727.
-
Nature
, vol.464
, Issue.7289
, pp. 721-727
-
-
Neumann, B.1
Walter, T.2
Heriche, J.K.3
Bulkescher, J.4
Erfle, H.5
Conrad, C.6
Rogers, P.7
Poser, I.8
Held, M.9
Liebel, U.10
-
9
-
-
58149521944
-
Highly parallel identification of essential genes in cancer cells
-
Luo B, Cheung HW, Subramanian A, Sharifnia T, Okamoto M, Yang X, Hinkle G, Boehm JS, Beroukhim R, Weir BA, et al. Highly parallel identification of essential genes in cancer cells. Proc Natl Acad Sci USA 2008, 105(51):20380-20385.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.51
, pp. 20380-20385
-
-
Luo, B.1
Cheung, H.W.2
Subramanian, A.3
Sharifnia, T.4
Okamoto, M.5
Yang, X.6
Hinkle, G.7
Boehm, J.S.8
Beroukhim, R.9
Weir, B.A.10
-
10
-
-
38849192515
-
Profiling essential genes in human mammary cells by multiplex RNAi screening
-
Silva JM, Marran K, Parker JS, Silva J, Golding M, Schlabach MR, Elledge SJ, Hannon GJ, Chang K. Profiling essential genes in human mammary cells by multiplex RNAi screening. Science 2008, 319(5863):617-620.
-
(2008)
Science
, vol.319
, Issue.5863
, pp. 617-620
-
-
Silva, J.M.1
Marran, K.2
Parker, J.S.3
Silva, J.4
Golding, M.5
Schlabach, M.R.6
Elledge, S.J.7
Hannon, G.J.8
Chang, K.9
-
11
-
-
66449112217
-
Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network
-
Tu Z, Argmann C, Wong KK, Mitnaul LJ, Edwards S, Sach IC, Zhu J, Schadt EE. Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network. Genome Res 2009, 19(6):1057-1067.
-
(2009)
Genome Res
, vol.19
, Issue.6
, pp. 1057-1067
-
-
Tu, Z.1
Argmann, C.2
Wong, K.K.3
Mitnaul, L.J.4
Edwards, S.5
Sach, I.C.6
Zhu, J.7
Schadt, E.E.8
-
12
-
-
54249117296
-
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds
-
Bakal C, Linding R, Llense F, Heffern E, Martin-Blanco E, Pawson T, Perrimon N. Phosphorylation networks regulating JNK activity in diverse genetic backgrounds. Science 2008, 322(5900):453-456.
-
(2008)
Science
, vol.322
, Issue.5900
, pp. 453-456
-
-
Bakal, C.1
Linding, R.2
Llense, F.3
Heffern, E.4
Martin-Blanco, E.5
Pawson, T.6
Perrimon, N.7
-
13
-
-
34548842261
-
Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads
-
Xu L, Yao X, Chen X, Lu P, Zhang B, Ip YT. Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads. J Cell Biol 2007, 178(6):981-994.
-
(2007)
J Cell Biol
, vol.178
, Issue.6
, pp. 981-994
-
-
Xu, L.1
Yao, X.2
Chen, X.3
Lu, P.4
Zhang, B.5
Ip, Y.T.6
-
14
-
-
28444451148
-
A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway
-
Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nat Genet 2005, 37(12):1323-1332.
-
(2005)
Nat Genet
, vol.37
, Issue.12
, pp. 1323-1332
-
-
Nybakken, K.1
Vokes, S.A.2
Lin, T.Y.3
McMahon, A.P.4
Perrimon, N.5
-
15
-
-
76749090540
-
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
-
Karlas A, Machuy N, Shin Y, Pleissner KP, Artarini A, Heuer D, Becker D, Khalil H, Ogilvie LA, Hess S, et al. Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication. Nature 2010, 463(7282):818-822.
-
(2010)
Nature
, vol.463
, Issue.7282
, pp. 818-822
-
-
Karlas, A.1
Machuy, N.2
Shin, Y.3
Pleissner, K.P.4
Artarini, A.5
Heuer, D.6
Becker, D.7
Khalil, H.8
Ogilvie, L.A.9
Hess, S.10
-
16
-
-
33746040565
-
Canonical Wnt signaling: high-throughput RNAi widens the path
-
Brown AM. Canonical Wnt signaling: high-throughput RNAi widens the path. Genome Biol 2005, 6(9):231.
-
(2005)
Genome Biol
, vol.6
, Issue.9
, pp. 231
-
-
Brown, A.M.1
-
17
-
-
0242361514
-
A functional genomic analysis of cell morphology using RNA interference
-
Kiger AA, Baum B, Jones S, Jones MR, Coulson A, Echeverri C, Perrimon N. A functional genomic analysis of cell morphology using RNA interference. J Biol 2003, 2(4):27.
-
(2003)
J Biol
, vol.2
, Issue.4
, pp. 27
-
-
Kiger, A.A.1
Baum, B.2
Jones, S.3
Jones, M.R.4
Coulson, A.5
Echeverri, C.6
Perrimon, N.7
-
18
-
-
48249098518
-
Identification of neural outgrowth genes using genome-wide RNAi
-
Sepp KJ, Hong P, Lizarraga SB, Liu JS, Mejia LA, Walsh CA, Perrimon N. Identification of neural outgrowth genes using genome-wide RNAi. PLoS Genet 2008, 4(7):e1000111.
-
(2008)
PLoS Genet
, vol.4
, Issue.7
-
-
Sepp, K.J.1
Hong, P.2
Lizarraga, S.B.3
Liu, J.S.4
Mejia, L.A.5
Walsh, C.A.6
Perrimon, N.7
-
19
-
-
46749137231
-
Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion
-
Huang X, Wang JY, Lu X. Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion. BMC Syst Biol 2008, 2:49.
-
(2008)
BMC Syst Biol
, vol.2
, pp. 49
-
-
Huang, X.1
Wang, J.Y.2
Lu, X.3
-
20
-
-
62849086387
-
Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology
-
Liu T, Sims D, Baum B. Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology. Genome Biol 2009, 10(3):R26.
-
(2009)
Genome Biol
, vol.10
, Issue.3
-
-
Liu, T.1
Sims, D.2
Baum, B.3
-
21
-
-
33845906334
-
A systematic RNA interference screen reveals a cell migration gene network in C. elegans
-
Cram EJ, Shang H, Schwarzbauer JE. A systematic RNA interference screen reveals a cell migration gene network in C. elegans. J Cell Sci 2006, 119(Pt 23):4811-4818.
-
(2006)
J Cell Sci
, vol.119
, Issue.PART 23
, pp. 4811-4818
-
-
Cram, E.J.1
Shang, H.2
Schwarzbauer, J.E.3
-
22
-
-
65549169178
-
Discovery of insect and human dengue virus host factors
-
Sessions OM, Barrows NJ, Souza-Neto JA, Robinson TJ, Hershey CL, Rodgers MA, Ramirez JL, Dimopoulos G, Yang PL, Pearson JL, et al. Discovery of insect and human dengue virus host factors. Nature 2009, 458(7241):1047-1050.
-
(2009)
Nature
, vol.458
, Issue.7241
, pp. 1047-1050
-
-
Sessions, O.M.1
Barrows, N.J.2
Souza-Neto, J.A.3
Robinson, T.J.4
Hershey, C.L.5
Rodgers, M.A.6
Ramirez, J.L.7
Dimopoulos, G.8
Yang, P.L.9
Pearson, J.L.10
-
23
-
-
23844442475
-
Genome-wide RNAi screen for host factors required for intracellular bacterial infection
-
Agaisse H, Burrack LS, Philips JA, Rubin EJ, Perrimon N, Higgins DE. Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science 2005, 309(5738):1248-1251.
-
(2005)
Science
, vol.309
, Issue.5738
, pp. 1248-1251
-
-
Agaisse, H.1
Burrack, L.S.2
Philips, J.A.3
Rubin, E.J.4
Perrimon, N.5
Higgins, D.E.6
-
24
-
-
51649095289
-
RNA interference screen for human genes associated with West Nile virus infection
-
Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, Sultana H, Brass AL, Adametz R, Tsui M, Qian F, et al. RNA interference screen for human genes associated with West Nile virus infection. Nature 2008, 455(7210):242-245.
-
(2008)
Nature
, vol.455
, Issue.7210
, pp. 242-245
-
-
Krishnan, M.N.1
Ng, A.2
Sukumaran, B.3
Gilfoy, F.D.4
Uchil, P.D.5
Sultana, H.6
Brass, A.L.7
Adametz, R.8
Tsui, M.9
Qian, F.10
-
25
-
-
33644873679
-
FlyRNAi: the Drosophila RNAi screening center database
-
Flockhart I, Booker M, Kiger A, Boutros M, Armknecht S, Ramadan N, Richardson K, Xu A, Perrimon N, Mathey-Prevot B. FlyRNAi: the Drosophila RNAi screening center database. Nucleic Acids Res 2006, (34 Database):D489-494.
-
(2006)
Nucleic Acids Res
, Issue.34
-
-
Flockhart, I.1
Booker, M.2
Kiger, A.3
Boutros, M.4
Armknecht, S.5
Ramadan, N.6
Richardson, K.7
Xu, A.8
Perrimon, N.9
Mathey-Prevot, B.10
-
26
-
-
75549087150
-
GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update
-
Gilsdorf M, Horn T, Arziman Z, Pelz O, Kiner E, Boutros M. GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update. Nucleic Acids Res 2009, (38 Database):D448-452.
-
(2009)
Nucleic Acids Res
, Issue.38
-
-
Gilsdorf, M.1
Horn, T.2
Arziman, Z.3
Pelz, O.4
Kiner, E.5
Boutros, M.6
-
27
-
-
77953626646
-
Genomic screening with RNAi: results and challenges
-
Mohr S, Bakal C, Perrimon N. Genomic screening with RNAi: results and challenges. Annu Rev Biochem 2010, 79:37-64.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 37-64
-
-
Mohr, S.1
Bakal, C.2
Perrimon, N.3
-
28
-
-
39349097864
-
Identification of host proteins required for HIV infection through a functional genomic screen
-
Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ. Identification of host proteins required for HIV infection through a functional genomic screen. Science 2008, 319(5865):921-926.
-
(2008)
Science
, vol.319
, Issue.5865
, pp. 921-926
-
-
Brass, A.L.1
Dykxhoorn, D.M.2
Benita, Y.3
Yan, N.4
Engelman, A.5
Xavier, R.J.6
Lieberman, J.7
Elledge, S.J.8
-
29
-
-
55249088255
-
Genome-scale RNAi screen for host factors required for HIV replication
-
Zhou H, Xu M, Huang Q, Gates AT, Zhang XD, Castle JC, Stec E, Ferrer M, Strulovici B, Hazuda DJ, et al. Genome-scale RNAi screen for host factors required for HIV replication. Cell Host Microbe 2008, 4(5):495-504.
-
(2008)
Cell Host Microbe
, vol.4
, Issue.5
, pp. 495-504
-
-
Zhou, H.1
Xu, M.2
Huang, Q.3
Gates, A.T.4
Zhang, X.D.5
Castle, J.C.6
Stec, E.7
Ferrer, M.8
Strulovici, B.9
Hazuda, D.J.10
-
30
-
-
36749016685
-
Genome-scale RNAi profiling of cell division in human tissue culture cells
-
Kittler R, Pelletier L, Heninger AK, Slabicki M, Theis M, Miroslaw L, Poser I, Lawo S, Grabner H, Kozak K, et al. Genome-scale RNAi profiling of cell division in human tissue culture cells. Nat Cell Biol 2007, 9(12):1401-1412.
-
(2007)
Nat Cell Biol
, vol.9
, Issue.12
, pp. 1401-1412
-
-
Kittler, R.1
Pelletier, L.2
Heninger, A.K.3
Slabicki, M.4
Theis, M.5
Miroslaw, L.6
Poser, I.7
Lawo, S.8
Grabner, H.9
Kozak, K.10
-
31
-
-
33749537857
-
Genome-wide functional analysis of human cell-cycle regulators
-
Mukherji M, Bell R, Supekova L, Wang Y, Orth AP, Batalov S, Miraglia L, Huesken D, Lange J, Martin C, et al. Genome-wide functional analysis of human cell-cycle regulators. Proc Natl Acad Sci USA 2006, 103(40):14819-14824.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.40
, pp. 14819-14824
-
-
Mukherji, M.1
Bell, R.2
Supekova, L.3
Wang, Y.4
Orth, A.P.5
Batalov, S.6
Miraglia, L.7
Huesken, D.8
Lange, J.9
Martin, C.10
-
32
-
-
23944468103
-
Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila
-
Baeg GH, Zhou R, Perrimon N. Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Genes Dev 2005, 19(16):1861-1870.
-
(2005)
Genes Dev
, vol.19
, Issue.16
, pp. 1861-1870
-
-
Baeg, G.H.1
Zhou, R.2
Perrimon, N.3
-
33
-
-
23844483215
-
Identification of JAK/STAT signalling components by genome-wide RNA interference
-
Muller P, Kuttenkeuler D, Gesellchen V, Zeidler MP, Boutros M. Identification of JAK/STAT signalling components by genome-wide RNA interference. Nature 2005, 436(7052):871-875.
-
(2005)
Nature
, vol.436
, Issue.7052
, pp. 871-875
-
-
Muller, P.1
Kuttenkeuler, D.2
Gesellchen, V.3
Zeidler, M.P.4
Boutros, M.5
-
34
-
-
33748939584
-
Prevalence of off-target effects in Drosophila RNA interference screens
-
Ma Y, Creanga A, Lum L, Beachy PA. Prevalence of off-target effects in Drosophila RNA interference screens. Nature 2006, 443(7109):359-363.
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 359-363
-
-
Ma, Y.1
Creanga, A.2
Lum, L.3
Beachy, P.A.4
-
35
-
-
33748994797
-
Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays
-
Kulkarni MM, Booker M, Silver SJ, Friedman A, Hong P, Perrimon N, Mathey-Prevot B. Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays. Nature methods 2006, 3(10):833-838.
-
(2006)
Nature methods
, vol.3
, Issue.10
, pp. 833-838
-
-
Kulkarni, M.M.1
Booker, M.2
Silver, S.J.3
Friedman, A.4
Hong, P.5
Perrimon, N.6
Mathey-Prevot, B.7
-
36
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol 2003, 21(6):635-637.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.6
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
37
-
-
0038121109
-
Specificity of short interfering RNA determined through gene expression signatures
-
Semizarov D, Frost L, Sarthy A, Kroeger P, Halbert DN, Fesik SW. Specificity of short interfering RNA determined through gene expression signatures. Proc Natl Acad Sci USA 2003, 100(11):6347-6352.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.11
, pp. 6347-6352
-
-
Semizarov, D.1
Frost, L.2
Sarthy, A.3
Kroeger, P.4
Halbert, D.N.5
Fesik, S.W.6
-
38
-
-
2442641279
-
Many commonly used siRNAs risk off-target activity
-
Snove O, Holen T. Many commonly used siRNAs risk off-target activity. Biochem Biophys Res Commun 2004, 319(1):256-263.
-
(2004)
Biochem Biophys Res Commun
, vol.319
, Issue.1
, pp. 256-263
-
-
Snove, O.1
Holen, T.2
-
39
-
-
75649110049
-
Selection of hyperfunctional siRNAs with improved potency and specificity
-
Wang X, Varma RK, Beauchamp L, Magdaleno S, Sendera TJ. Selection of hyperfunctional siRNAs with improved potency and specificity. Nucleic Acids Res 2009, 37(22):e152.
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.22
-
-
Wang, X.1
Varma, R.K.2
Beauchamp, L.3
Magdaleno, S.4
Sendera, T.J.5
-
40
-
-
58149234807
-
Cost-effective strategies for completing the interactome
-
Schwartz AS, Yu J, Gardenour KR, Finley RL, Ideker T. Cost-effective strategies for completing the interactome. Nature methods 2009, 6(1):55-61.
-
(2009)
Nature methods
, vol.6
, Issue.1
, pp. 55-61
-
-
Schwartz, A.S.1
Yu, J.2
Gardenour, K.R.3
Finley, R.L.4
Ideker, T.5
-
41
-
-
0033669189
-
A network of protein-protein interactions in yeast
-
Schwikowski B, Uetz P, Fields S. A network of protein-protein interactions in yeast. Nat Biotechnol 2000, 18(12):1257-1261.
-
(2000)
Nat Biotechnol
, vol.18
, Issue.12
, pp. 1257-1261
-
-
Schwikowski, B.1
Uetz, P.2
Fields, S.3
-
42
-
-
0036789265
-
Analyzing yeast protein-protein interaction data obtained from different sources
-
Bader GD, Hogue CW. Analyzing yeast protein-protein interaction data obtained from different sources. Nat Biotechnol 2002, 20(10):991-997.
-
(2002)
Nat Biotechnol
, vol.20
, Issue.10
, pp. 991-997
-
-
Bader, G.D.1
Hogue, C.W.2
-
43
-
-
0036580169
-
Protein interactions: two methods for assessment of the reliability of high throughput observations
-
Deane CM, Salwinski L, Xenarios I, Eisenberg D. Protein interactions: two methods for assessment of the reliability of high throughput observations. Mol Cell Proteomics 2002, 1(5):349-356.
-
(2002)
Mol Cell Proteomics
, vol.1
, Issue.5
, pp. 349-356
-
-
Deane, C.M.1
Salwinski, L.2
Xenarios, I.3
Eisenberg, D.4
-
44
-
-
0345600247
-
A protein interaction map of Drosophila melanogaster
-
Giot L, Bader JS, Brouwer C, Chaudhuri A, Kuang B, Li Y, Hao YL, Ooi CE, Godwin B, Vitols E, et al. A protein interaction map of Drosophila melanogaster. Science 2003, 302(5651):1727-1736.
-
(2003)
Science
, vol.302
, Issue.5651
, pp. 1727-1736
-
-
Giot, L.1
Bader, J.S.2
Brouwer, C.3
Chaudhuri, A.4
Kuang, B.5
Li, Y.6
Hao, Y.L.7
Ooi, C.E.8
Godwin, B.9
Vitols, E.10
-
45
-
-
9144264169
-
A map of the interactome network of the metazoan C. elegans
-
Li S, Armstrong CM, Bertin N, Ge H, Milstein S, Boxem M, Vidalain PO, Han JD, Chesneau A, Hao T, et al. A map of the interactome network of the metazoan C. elegans. Science 2004, 303(5657):540-543.
-
(2004)
Science
, vol.303
, Issue.5657
, pp. 540-543
-
-
Li, S.1
Armstrong, C.M.2
Bertin, N.3
Ge, H.4
Milstein, S.5
Boxem, M.6
Vidalain, P.O.7
Han, J.D.8
Chesneau, A.9
Hao, T.10
-
46
-
-
53349117774
-
High-quality binary protein interaction map of the yeast interactome network
-
Yu H, Braun P, Yildirim MA, Lemmens I, Venkatesan K, Sahalie J, Hirozane-Kishikawa T, Gebreab F, Li N, Simonis N, et al. High-quality binary protein interaction map of the yeast interactome network. Science 2008, 322(5898):104-110.
-
(2008)
Science
, vol.322
, Issue.5898
, pp. 104-110
-
-
Yu, H.1
Braun, P.2
Yildirim, M.A.3
Lemmens, I.4
Venkatesan, K.5
Sahalie, J.6
Hirozane-Kishikawa, T.7
Gebreab, F.8
Li, N.9
Simonis, N.10
-
47
-
-
33645453254
-
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae
-
Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 2006, 440:637-643.
-
(2006)
Nature
, vol.440
, pp. 637-643
-
-
Krogan, N.J.1
Cagney, G.2
Yu, H.3
Zhong, G.4
Guo, X.5
Ignatchenko, A.6
Li, J.7
Pu, S.8
Datta, N.9
Tikuisis, A.P.10
-
48
-
-
34548024598
-
Integrating physical and genetic maps: from genomes to interaction networks
-
Beyer A, Bandyopadhyay S, Ideker T. Integrating physical and genetic maps: from genomes to interaction networks. Nature reviews 2007, 8(9):699-710.
-
(2007)
Nature reviews
, vol.8
, Issue.9
, pp. 699-710
-
-
Beyer, A.1
Bandyopadhyay, S.2
Ideker, T.3
-
49
-
-
33846681448
-
Modular organization of protein interaction networks
-
Luo F, Yang Y, Chen CF, Chang R, Zhou J, Scheuermann RH. Modular organization of protein interaction networks. Bioinformatics 2007, 23(2):207-214.
-
(2007)
Bioinformatics
, vol.23
, Issue.2
, pp. 207-214
-
-
Luo, F.1
Yang, Y.2
Chen, C.F.3
Chang, R.4
Zhou, J.5
Scheuermann, R.H.6
-
50
-
-
33745619564
-
Exploiting indirect neighbours and topological weight to predict protein function from protein-protein interactions
-
Chua HN, Sung WK, Wong L. Exploiting indirect neighbours and topological weight to predict protein function from protein-protein interactions. Bioinformatics 2006, 22(13):1623-1630.
-
(2006)
Bioinformatics
, vol.22
, Issue.13
, pp. 1623-1630
-
-
Chua, H.N.1
Sung, W.K.2
Wong, L.3
-
51
-
-
58149218155
-
Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network
-
Simonis N, Rual JF, Carvunis AR, Tasan M, Lemmens I, Hirozane-Kishikawa T, Hao T, Sahalie JM, Venkatesan K, Gebreab F, et al. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Nature methods 2009, 6(1):47-54.
-
(2009)
Nature methods
, vol.6
, Issue.1
, pp. 47-54
-
-
Simonis, N.1
Rual, J.F.2
Carvunis, A.R.3
Tasan, M.4
Lemmens, I.5
Hirozane-Kishikawa, T.6
Hao, T.7
Sahalie, J.M.8
Venkatesan, K.9
Gebreab, F.10
-
52
-
-
0038699587
-
Global protein function prediction from protein-protein interaction networks
-
Vazquez A, Flammini A, Maritan A, Vespignani A. Global protein function prediction from protein-protein interaction networks. Nat Biotechnol 2003, 21(6):697-700.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.6
, pp. 697-700
-
-
Vazquez, A.1
Flammini, A.2
Maritan, A.3
Vespignani, A.4
-
53
-
-
0035044077
-
Assessment of prediction accuracy of protein function from protein--protein interaction data
-
Hishigaki H, Nakai K, Ono T, Tanigami A, Takagi T. Assessment of prediction accuracy of protein function from protein--protein interaction data. Yeast 2001, 18(6):523-531.
-
(2001)
Yeast
, vol.18
, Issue.6
, pp. 523-531
-
-
Hishigaki, H.1
Nakai, K.2
Ono, T.3
Tanigami, A.4
Takagi, T.5
-
54
-
-
0142059836
-
Protein complexes and functional modules in molecular networks
-
Spirin V, Mirny LA. Protein complexes and functional modules in molecular networks. Proc Natl Acad Sci USA 2003, 100(21):12123-12128.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.21
, pp. 12123-12128
-
-
Spirin, V.1
Mirny, L.A.2
-
55
-
-
0242268461
-
Predicting protein functions from redundancies in large-scale protein interaction networks
-
Samanta MP, Liang S. Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci USA 2003, 100(22):12579-12583.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.22
, pp. 12579-12583
-
-
Samanta, M.P.1
Liang, S.2
-
56
-
-
0035733690
-
Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae
-
Ge H, Liu Z, Church GM, Vidal M. Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae. Nat Genet 2001, 29(4):482-486.
-
(2001)
Nat Genet
, vol.29
, Issue.4
, pp. 482-486
-
-
Ge, H.1
Liu, Z.2
Church, G.M.3
Vidal, M.4
-
57
-
-
0037016444
-
Combined functional genomic maps of the C. elegans DNA damage response
-
Boulton SJ, Gartner A, Reboul J, Vaglio P, Dyson N, Hill DE, Vidal M. Combined functional genomic maps of the C. elegans DNA damage response. Science 2002, 295(5552):127-131.
-
(2002)
Science
, vol.295
, Issue.5552
, pp. 127-131
-
-
Boulton, S.J.1
Gartner, A.2
Reboul, J.3
Vaglio, P.4
Dyson, N.5
Hill, D.E.6
Vidal, M.7
-
58
-
-
47549104748
-
Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function
-
Tian W, Zhang LV, Tasan M, Gibbons FD, King OD, Park J, Wunderlich Z, Cherry JM, Roth FP. Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 2008, 9(Suppl 1):S7.
-
(2008)
Genome Biol
, vol.9
, Issue.SUPPL. 1
-
-
Tian, W.1
Zhang, L.V.2
Tasan, M.3
Gibbons, F.D.4
King, O.D.5
Park, J.6
Wunderlich, Z.7
Cherry, J.M.8
Roth, F.P.9
-
60
-
-
33644503868
-
Identification of pathways regulating cell size and cell-cycle progression by RNAi
-
Bjorklund M, Taipale M, Varjosalo M, Saharinen J, Lahdenpera J, Taipale J. Identification of pathways regulating cell size and cell-cycle progression by RNAi. Nature 2006, 439(7079):1009-1013.
-
(2006)
Nature
, vol.439
, Issue.7079
, pp. 1009-1013
-
-
Bjorklund, M.1
Taipale, M.2
Varjosalo, M.3
Saharinen, J.4
Lahdenpera, J.5
Taipale, J.6
-
61
-
-
19944413010
-
Genome-wide survey of protein kinases required for cell cycle progression
-
Bettencourt-Dias M, Giet R, Sinka R, Mazumdar A, Lock WG, Balloux F, Zafiropoulos PJ, Yamaguchi S, Winter S, Carthew RW, et al. Genome-wide survey of protein kinases required for cell cycle progression. Nature 2004, 432(7020):980-987.
-
(2004)
Nature
, vol.432
, Issue.7020
, pp. 980-987
-
-
Bettencourt-Dias, M.1
Giet, R.2
Sinka, R.3
Mazumdar, A.4
Lock, W.G.5
Balloux, F.6
Zafiropoulos, P.J.7
Yamaguchi, S.8
Winter, S.9
Carthew, R.W.10
-
62
-
-
75849158230
-
The Gene Ontology in 2010: extensions and refinements
-
Consortium GO. The Gene Ontology in 2010: extensions and refinements. Nucleic Acids Res 2010, 38 Database:D331-335.
-
(2010)
Nucleic Acids Res
, vol.38 Database
-
-
Consortium, G.O.1
-
63
-
-
54949120007
-
DroID: the Drosophila Interactions Database, a comprehensive resource for annotated gene and protein interactions
-
Yu J, Pacifico S, Liu G, Finley RL, Jr. DroID: the Drosophila Interactions Database, a comprehensive resource for annotated gene and protein interactions. BMC Genomics 2008, 9:461.
-
(2008)
BMC Genomics
, vol.9
, pp. 461
-
-
Yu, J.1
Pacifico, S.2
Liu, G.3
Finley, R.L.4
Jr5
-
64
-
-
78651343711
-
DroID 2011: A comprehensive integrated reources for protein, transcription factor, RNA, and gene interactions for Drosophila
-
Murali T, Pacifico S, Yu J, Guest S, Roberts GG, Finley RLJ. DroID 2011: A comprehensive integrated reources for protein, transcription factor, RNA, and gene interactions for Drosophila. Nucleic Acids Research 2011, 39:D736-43.
-
(2011)
Nucleic Acids Research
, vol.39
-
-
Murali, T.1
Pacifico, S.2
Yu, J.3
Guest, S.4
Roberts, G.G.5
Finley, R.L.J.6
-
65
-
-
4544374422
-
Terminal cytokinesis events uncovered after an RNAi screen
-
Echard A, Hickson GR, Foley E, O'Farrell PH. Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol 2004, 14(18):1685-1693.
-
(2004)
Curr Biol
, vol.14
, Issue.18
, pp. 1685-1693
-
-
Echard, A.1
Hickson, G.R.2
Foley, E.3
O'Farrell, P.H.4
-
66
-
-
58049215468
-
Combining multiple positive training sets to generate confidence scores for protein-protein interactions
-
Yu J, Finley RL. Combining multiple positive training sets to generate confidence scores for protein-protein interactions. Bioinformatics 2009, 25(1):105-111.
-
(2009)
Bioinformatics
, vol.25
, Issue.1
, pp. 105-111
-
-
Yu, J.1
Finley, R.L.2
-
67
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009, 4(1):44-57.
-
(2009)
Nat Protoc
, vol.4
, Issue.1
, pp. 44-57
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
68
-
-
44049098353
-
A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila
-
DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N. A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. Genome Biol 2007, 8(9):R203.
-
(2007)
Genome Biol
, vol.8
, Issue.9
-
-
DasGupta, R.1
Nybakken, K.2
Booker, M.3
Mathey-Prevot, B.4
Gonsalves, F.5
Changkakoty, B.6
Perrimon, N.7
-
69
-
-
67651219232
-
A network of conserved damage survival pathways revealed by a genomic RNAi screen
-
Ravi D, Wiles AM, Bhavani S, Ruan J, Leder P, Bishop AJ. A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 2009, 5(6):e1000527.
-
(2009)
PLoS Genet
, vol.5
, Issue.6
-
-
Ravi, D.1
Wiles, A.M.2
Bhavani, S.3
Ruan, J.4
Leder, P.5
Bishop, A.J.6
-
70
-
-
49649127852
-
Drosophila RNAi screen identifies host genes important for influenza virus replication
-
Hao L, Sakurai A, Watanabe T, Sorensen E, Nidom CA, Newton MA, Ahlquist P, Kawaoka Y. Drosophila RNAi screen identifies host genes important for influenza virus replication. Nature 2008, 454(7206):890-893.
-
(2008)
Nature
, vol.454
, Issue.7206
, pp. 890-893
-
-
Hao, L.1
Sakurai, A.2
Watanabe, T.3
Sorensen, E.4
Nidom, C.A.5
Newton, M.A.6
Ahlquist, P.7
Kawaoka, Y.8
-
71
-
-
33749023011
-
Minimizing the risk of reporting false positives in large-scale RNAi screens
-
Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, et al. Minimizing the risk of reporting false positives in large-scale RNAi screens. Nature methods 2006, 3(10):777-779.
-
(2006)
Nature methods
, vol.3
, Issue.10
, pp. 777-779
-
-
Echeverri, C.J.1
Beachy, P.A.2
Baum, B.3
Boutros, M.4
Buchholz, F.5
Chanda, S.K.6
Downward, J.7
Ellenberg, J.8
Fraser, A.G.9
Hacohen, N.10
-
72
-
-
3142536716
-
Exploration of essential gene functions via titratable promoter alleles
-
Mnaimneh S, Davierwala AP, Haynes J, Moffat J, Peng WT, Zhang W, Yang X, Pootoolal J, Chua G, Lopez A, et al. Exploration of essential gene functions via titratable promoter alleles. Cell 2004, 118(1):31-44.
-
(2004)
Cell
, vol.118
, Issue.1
, pp. 31-44
-
-
Mnaimneh, S.1
Davierwala, A.P.2
Haynes, J.3
Moffat, J.4
Peng, W.T.5
Zhang, W.6
Yang, X.7
Pootoolal, J.8
Chua, G.9
Lopez, A.10
-
73
-
-
79958280838
-
System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae
-
Gresham D, Boer V, Caudy A, Ziv N, Brandt NJ, Storey JD, Botstein D. System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae. Genetics 2010,
-
(2010)
Genetics
-
-
Gresham, D.1
Boer, V.2
Caudy, A.3
Ziv, N.4
Brandt, N.J.5
Storey, J.D.6
Botstein, D.7
-
74
-
-
1542298437
-
Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions
-
Simmer F, Moorman C, van der Linden AM, Kuijk E, van den Berghe PV, Kamath RS, Fraser AG, Ahringer J, Plasterk RH. Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS biology 2003, 1(1):E12.
-
(2003)
PLoS biology
, vol.1
, Issue.1
-
-
Simmer, F.1
Moorman, C.2
van der Linden, A.M.3
Kuijk, E.4
van den Berghe, P.V.5
Kamath, R.S.6
Fraser, A.G.7
Ahringer, J.8
Plasterk, R.H.9
-
75
-
-
14844312915
-
Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo
-
Tanackovic G, Kramer A. Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo. Mol Biol Cell 2005, 16(3):1366-1377.
-
(2005)
Mol Biol Cell
, vol.16
, Issue.3
, pp. 1366-1377
-
-
Tanackovic, G.1
Kramer, A.2
-
76
-
-
12344288635
-
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets
-
Eggert US, Kiger AA, Richter C, Perlman ZE, Perrimon N, Mitchison TJ, Field CM. Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS biology 2004, 2(12):e379.
-
(2004)
PLoS biology
, vol.2
, Issue.12
-
-
Eggert, U.S.1
Kiger, A.A.2
Richter, C.3
Perlman, Z.E.4
Perrimon, N.5
Mitchison, T.J.6
Field, C.M.7
-
77
-
-
36249024229
-
Cytokinesis: placing and making the final cut
-
Barr FA, Gruneberg U. Cytokinesis: placing and making the final cut. Cell 2007, 131(5):847-860.
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 847-860
-
-
Barr, F.A.1
Gruneberg, U.2
-
78
-
-
33747831132
-
L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage
-
Higa LA, Banks D, Wu M, Kobayashi R, Sun H, Zhang H. L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage. Cell Cycle 2006, 5(15):1675-1680.
-
(2006)
Cell Cycle
, vol.5
, Issue.15
, pp. 1675-1680
-
-
Higa, L.A.1
Banks, D.2
Wu, M.3
Kobayashi, R.4
Sun, H.5
Zhang, H.6
-
79
-
-
0347948462
-
Characterization of the Drosophila Rae1 protein as a G1 phase regulator of the cell cycle
-
Sitterlin D. Characterization of the Drosophila Rae1 protein as a G1 phase regulator of the cell cycle. Gene 2004, 326:107-116.
-
(2004)
Gene
, vol.326
, pp. 107-116
-
-
Sitterlin, D.1
-
80
-
-
34248209547
-
Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy
-
Higa LA, Zhang H. Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy. Cell Div 2007, 2:5.
-
(2007)
Cell Div
, vol.2
, pp. 5
-
-
Higa, L.A.1
Zhang, H.2
-
81
-
-
0242525214
-
Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint
-
Higa LA, Mihaylov IS, Banks DP, Zheng J, Zhang H. Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint. Nat Cell Biol 2003, 5(11):1008-1015.
-
(2003)
Nat Cell Biol
, vol.5
, Issue.11
, pp. 1008-1015
-
-
Higa, L.A.1
Mihaylov, I.S.2
Banks, D.P.3
Zheng, J.4
Zhang, H.5
-
82
-
-
33747823839
-
L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes
-
Banks D, Wu M, Higa LA, Gavrilova N, Quan J, Ye T, Kobayashi R, Sun H, Zhang H. L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes. Cell Cycle 2006, 5(15):1719-1729.
-
(2006)
Cell Cycle
, vol.5
, Issue.15
, pp. 1719-1729
-
-
Banks, D.1
Wu, M.2
Higa, L.A.3
Gavrilova, N.4
Quan, J.5
Ye, T.6
Kobayashi, R.7
Sun, H.8
Zhang, H.9
-
83
-
-
33751232623
-
Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma
-
Pan HW, Chou HY, Liu SH, Peng SY, Liu CL, Hsu HC. Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma. Cell Cycle 2006, 5(22):2676-2687.
-
(2006)
Cell Cycle
, vol.5
, Issue.22
, pp. 2676-2687
-
-
Pan, H.W.1
Chou, H.Y.2
Liu, S.H.3
Peng, S.Y.4
Liu, C.L.5
Hsu, H.C.6
-
84
-
-
0031836475
-
Homologues of 26S proteasome subunits are regulators of transcription and translation
-
Aravind L, Ponting CP. Homologues of 26S proteasome subunits are regulators of transcription and translation. Protein Sci 1998, 7(5):1250-1254.
-
(1998)
Protein Sci
, vol.7
, Issue.5
, pp. 1250-1254
-
-
Aravind, L.1
Ponting, C.P.2
-
85
-
-
0032104227
-
The PCI domain: a common theme in three multiprotein complexes
-
Hofmann K, Bucher P. The PCI domain: a common theme in three multiprotein complexes. Trends Biochem Sci 1998, 23(6):204-205.
-
(1998)
Trends Biochem Sci
, vol.23
, Issue.6
, pp. 204-205
-
-
Hofmann, K.1
Bucher, P.2
-
86
-
-
0028844991
-
Ectopic cyclin E expression induces premature entry into S phase and disrupts pattern formation in the Drosophila eye imaginal disc
-
Richardson H, O'Keefe LV, Marty T, Saint R. Ectopic cyclin E expression induces premature entry into S phase and disrupts pattern formation in the Drosophila eye imaginal disc. Development 1995, 121:3371-3379.
-
(1995)
Development
, vol.121
, pp. 3371-3379
-
-
Richardson, H.1
O'Keefe, L.V.2
Marty, T.3
Saint, R.4
-
87
-
-
0028358931
-
Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation
-
Knoblich JA, Sauer K, Jones L, Richardson H, Saint R, Lehner CF. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell 1994, 77(1):107-120.
-
(1994)
Cell
, vol.77
, Issue.1
, pp. 107-120
-
-
Knoblich, J.A.1
Sauer, K.2
Jones, L.3
Richardson, H.4
Saint, R.5
Lehner, C.F.6
-
88
-
-
0027332123
-
Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes
-
Dulic V, Drullinger LF, Lees E, Reed SI, Stein GH. Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc Natl Acad Sci USA 1993, 90(23):11034-11038.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.23
, pp. 11034-11038
-
-
Dulic, V.1
Drullinger, L.F.2
Lees, E.3
Reed, S.I.4
Stein, G.H.5
-
89
-
-
0027298902
-
The cdk2 kinase is required for the G1-to-S transition in mammalian cells
-
Tsai LH, Lees E, Faha B, Harlow E, Riabowol K. The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene 1993, 8(6):1593-1602.
-
(1993)
Oncogene
, vol.8
, Issue.6
, pp. 1593-1602
-
-
Tsai, L.H.1
Lees, E.2
Faha, B.3
Harlow, E.4
Riabowol, K.5
-
90
-
-
0029013865
-
Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis
-
Sauer K, Knoblich JA, Richardson H, Lehner CF. Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes Dev 1995, 9(11):1327-1339.
-
(1995)
Genes Dev
, vol.9
, Issue.11
, pp. 1327-1339
-
-
Sauer, K.1
Knoblich, J.A.2
Richardson, H.3
Lehner, C.F.4
-
91
-
-
0028980858
-
Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F
-
Duronio RJ, O'Farrell PH. Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F. Genes Dev 1995, 9(12):1456-1468.
-
(1995)
Genes Dev
, vol.9
, Issue.12
, pp. 1456-1468
-
-
Duronio, R.J.1
O'Farrell, P.H.2
-
92
-
-
0027513590
-
Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts
-
Pagano M, Pepperkok R, Lukas J, Baldin V, Ansorge W, Bartek J, Draetta G. Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts. J of Cell Biol 1993, 121(1):101-111.
-
(1993)
J of Cell Biol
, vol.121
, Issue.1
, pp. 101-111
-
-
Pagano, M.1
Pepperkok, R.2
Lukas, J.3
Baldin, V.4
Ansorge, W.5
Bartek, J.6
Draetta, G.7
-
93
-
-
0030468329
-
Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development
-
Lane ME, Sauer K, Wallace K, Jan YN, Lehner CF, Vaessin H. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell 1996, 87(7):1225-1235.
-
(1996)
Cell
, vol.87
, Issue.7
, pp. 1225-1235
-
-
Lane, M.E.1
Sauer, K.2
Wallace, K.3
Jan, Y.N.4
Lehner, C.F.5
Vaessin, H.6
-
94
-
-
0030473888
-
A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis
-
de Nooij JC, Letendre MA, Hariharan IK. A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell 1996, 87(7):1237-1247.
-
(1996)
Cell
, vol.87
, Issue.7
, pp. 1237-1247
-
-
de Nooij, J.C.1
Letendre, M.A.2
Hariharan, I.K.3
-
95
-
-
33645309411
-
Involvement of CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27Kip1 and cyclin E degradation
-
Higa LA, Yang X, Zheng J, Banks D, Wu M, Ghosh P, Sun H, Zhang H. Involvement of CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27Kip1 and cyclin E degradation. Cell Cycle 2006, 5(1):71-77.
-
(2006)
Cell Cycle
, vol.5
, Issue.1
, pp. 71-77
-
-
Higa, L.A.1
Yang, X.2
Zheng, J.3
Banks, D.4
Wu, M.5
Ghosh, P.6
Sun, H.7
Zhang, H.8
-
96
-
-
0032556952
-
P21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
-
Cayrol C, Knibiehler M, Ducommun B. p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells. Oncogene 1998, 16(3):311-320.
-
(1998)
Oncogene
, vol.16
, Issue.3
, pp. 311-320
-
-
Cayrol, C.1
Knibiehler, M.2
Ducommun, B.3
-
97
-
-
0029024015
-
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano M, Tam SW, Theodoras AM, Beer-Romero P, Del Sal G, Chau V, Yew PR, Draetta GF, Rolfe M. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995, 269(5224):682-685.
-
(1995)
Science
, vol.269
, Issue.5224
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
Beer-Romero, P.4
Del Sal, G.5
Chau, V.6
Yew, P.R.7
Draetta, G.F.8
Rolfe, M.9
-
98
-
-
0028568642
-
Purified yeast translational initiation factor eIF-3 is an RNA-binding protein complex that contains the PRT1 protein
-
Naranda T, MacMillan SE, Hershey JW. Purified yeast translational initiation factor eIF-3 is an RNA-binding protein complex that contains the PRT1 protein. J Biol Chem 1994, 269(51):32286-32292.
-
(1994)
J Biol Chem
, vol.269
, Issue.51
, pp. 32286-32292
-
-
Naranda, T.1
MacMillan, S.E.2
Hershey, J.W.3
-
99
-
-
0028947302
-
Isolation of a protein complex containing translation initiation factor Prt1 from Saccharomyces cerevisiae
-
Danaie P, Wittmer B, Altmann M, Trachsel H. Isolation of a protein complex containing translation initiation factor Prt1 from Saccharomyces cerevisiae. J Biol Chem 1995, 270(9):4288-4292.
-
(1995)
J Biol Chem
, vol.270
, Issue.9
, pp. 4288-4292
-
-
Danaie, P.1
Wittmer, B.2
Altmann, M.3
Trachsel, H.4
-
100
-
-
0023408753
-
Regulated arrest of cell proliferation mediated by yeast prt1 mutations
-
Hanic-Joyce PJ, Johnston GC, Singer RA. Regulated arrest of cell proliferation mediated by yeast prt1 mutations. Exp Cell Res 1987, 172(1):134-145.
-
(1987)
Exp Cell Res
, vol.172
, Issue.1
, pp. 134-145
-
-
Hanic-Joyce, P.J.1
Johnston, G.C.2
Singer, R.A.3
-
101
-
-
0023664013
-
Molecular characterization of the yeast PRT1 gene in which mutations affect translation initiation and regulation of cell proliferation
-
Hanic-Joyce PJ, Singer RA, Johnston GC. Molecular characterization of the yeast PRT1 gene in which mutations affect translation initiation and regulation of cell proliferation. J Biol Chem 1987, 262(6):2845-2851.
-
(1987)
J Biol Chem
, vol.262
, Issue.6
, pp. 2845-2851
-
-
Hanic-Joyce, P.J.1
Singer, R.A.2
Johnston, G.C.3
-
102
-
-
0031023534
-
The 39-kilodalton subunit of eukaryotic translation initiation factor 3 is essential for the complex's integrity and for cell viability in Saccharomyces cerevisiae
-
Naranda T, Kainuma M, MacMillan SE, Hershey JW. The 39-kilodalton subunit of eukaryotic translation initiation factor 3 is essential for the complex's integrity and for cell viability in Saccharomyces cerevisiae. Mol Cell Biol 1997, 17(1):145-153.
-
(1997)
Mol Cell Biol
, vol.17
, Issue.1
, pp. 145-153
-
-
Naranda, T.1
Kainuma, M.2
MacMillan, S.E.3
Hershey, J.W.4
-
103
-
-
0030832613
-
Identification of partners of TIF34, a component of the yeast eIF3 complex, required for cell proliferation and translation initiation
-
Verlhac MH, Chen RH, Hanachi P, Hershey JW, Derynck R. Identification of partners of TIF34, a component of the yeast eIF3 complex, required for cell proliferation and translation initiation. EMBO J 1997, 16(22):6812-6822.
-
(1997)
EMBO J
, vol.16
, Issue.22
, pp. 6812-6822
-
-
Verlhac, M.H.1
Chen, R.H.2
Hanachi, P.3
Hershey, J.W.4
Derynck, R.5
-
104
-
-
34247165835
-
Individual overexpression of five subunits of human translation initiation factor eIF3 promotes malignant transformation of immortal fibroblast cells
-
Zhang L, Pan X, Hershey JW. Individual overexpression of five subunits of human translation initiation factor eIF3 promotes malignant transformation of immortal fibroblast cells. J Biol Chem 2007, 282(8):5790-5800.
-
(2007)
J Biol Chem
, vol.282
, Issue.8
, pp. 5790-5800
-
-
Zhang, L.1
Pan, X.2
Hershey, J.W.3
-
105
-
-
0027332390
-
A drosophila G(1)-specific cyclin E homolog exhibits different modes of expression during embryogenesis
-
Richardson HE, Okeefe LV, Reed SI, Saint R. A drosophila G(1)-specific cyclin E homolog exhibits different modes of expression during embryogenesis. Development 1993, 119(3):673-690.
-
(1993)
Development
, vol.119
, Issue.3
, pp. 673-690
-
-
Richardson, H.E.1
Okeefe, L.V.2
Reed, S.I.3
Saint, R.4
-
106
-
-
33748924333
-
EIF3: a versatile scaffold for translation initiation complexes
-
Hinnebusch AG. eIF3: a versatile scaffold for translation initiation complexes. Trends Biochem Sci 2006, 31(10):553-562.
-
(2006)
Trends Biochem Sci
, vol.31
, Issue.10
, pp. 553-562
-
-
Hinnebusch, A.G.1
-
107
-
-
38649138295
-
A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans
-
Lee I, Lehner B, Crombie C, Wong W, Fraser AG, Marcotte EM. A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans. Nat Genet 2008, 40(2):181-188.
-
(2008)
Nat Genet
, vol.40
, Issue.2
, pp. 181-188
-
-
Lee, I.1
Lehner, B.2
Crombie, C.3
Wong, W.4
Fraser, A.G.5
Marcotte, E.M.6
-
108
-
-
10744231500
-
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network
-
Tewari M, Hu PJ, Ahn JS, Ayivi-Guedehoussou N, Vidalain PO, Li S, Milstein S, Armstrong CM, Boxem M, Butler MD, et al. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Mol Cell 2004, 13(4):469-482.
-
(2004)
Mol Cell
, vol.13
, Issue.4
, pp. 469-482
-
-
Tewari, M.1
Hu, P.J.2
Ahn, J.S.3
Ayivi-Guedehoussou, N.4
Vidalain, P.O.5
Li, S.6
Milstein, S.7
Armstrong, C.M.8
Boxem, M.9
Butler, M.D.10
-
109
-
-
67649124461
-
A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila
-
Wang L, Tu Z, Sun F. A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila. BMC Genomics 2009, 10:220.
-
(2009)
BMC Genomics
, vol.10
, pp. 220
-
-
Wang, L.1
Tu, Z.2
Sun, F.3
-
110
-
-
67649601037
-
RNAiCut: automated detection of significant genes from functional genomic screens
-
Kaplow IM, Singh R, Friedman A, Bakal C, Perrimon N, Berger B. RNAiCut: automated detection of significant genes from functional genomic screens. Nature methods 2009, 6(7):476-477.
-
(2009)
Nature methods
, vol.6
, Issue.7
, pp. 476-477
-
-
Kaplow, I.M.1
Singh, R.2
Friedman, A.3
Bakal, C.4
Perrimon, N.5
Berger, B.6
-
111
-
-
0033545636
-
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
-
Tomoda K, Kubota Y, Kato J. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 1999, 398(6723):160-165.
-
(1999)
Nature
, vol.398
, Issue.6723
, pp. 160-165
-
-
Tomoda, K.1
Kubota, Y.2
Kato, J.3
-
112
-
-
33845939310
-
The COP9 signalosome regulates Skp2 levels and proliferation of human cells
-
Denti S, Fernandez-Sanchez ME, Rogge L, Bianchi E. The COP9 signalosome regulates Skp2 levels and proliferation of human cells. J Biol Chem 2006, 281(43):32188-32196.
-
(2006)
J Biol Chem
, vol.281
, Issue.43
, pp. 32188-32196
-
-
Denti, S.1
Fernandez-Sanchez, M.E.2
Rogge, L.3
Bianchi, E.4
-
113
-
-
24944458255
-
Modulation of differentiation-related gene 1 expression by cell cycle blocker mimosine, revealed by proteomic analysis
-
Dong Z, Arnold RJ, Yang Y, Park MH, Hrncirova P, Mechref Y, Novotny MV, Zhang JT. Modulation of differentiation-related gene 1 expression by cell cycle blocker mimosine, revealed by proteomic analysis. Mol Cell Proteomics 2005, 4(7):993-1001.
-
(2005)
Mol Cell Proteomics
, vol.4
, Issue.7
, pp. 993-1001
-
-
Dong, Z.1
Arnold, R.J.2
Yang, Y.3
Park, M.H.4
Hrncirova, P.5
Mechref, Y.6
Novotny, M.V.7
Zhang, J.T.8
-
114
-
-
0141521573
-
EIF3 p170, a mediator of mimosine effect on protein synthesis and cell cycle progression
-
Dong Z, Zhang JT. EIF3 p170, a mediator of mimosine effect on protein synthesis and cell cycle progression. Mol Biol Cell 2003, 14(9):3942-3951.
-
(2003)
Mol Biol Cell
, vol.14
, Issue.9
, pp. 3942-3951
-
-
Dong, Z.1
Zhang, J.T.2
-
115
-
-
34347397000
-
Human TopBP1 participates in cyclin E/CDK2 activation and preinitiation complex assembly during G1/S transition
-
Jeon Y, Lee KY, Ko MJ, Lee YS, Kang S, Hwang DS. Human TopBP1 participates in cyclin E/CDK2 activation and preinitiation complex assembly during G1/S transition. J Biol Chem 2007, 282(20):14882-14890.
-
(2007)
J Biol Chem
, vol.282
, Issue.20
, pp. 14882-14890
-
-
Jeon, Y.1
Lee, K.Y.2
Ko, M.J.3
Lee, Y.S.4
Kang, S.5
Hwang, D.S.6
-
116
-
-
58149199579
-
FlyBase: enhancing Drosophila Gene Ontology annotations
-
Tweedie S, Ashburner M, Falls K, Leyland P, McQuilton P, Marygold S, Millburn G, Osumi-Sutherland D, Schroeder A, Seal R, et al. FlyBase: enhancing Drosophila Gene Ontology annotations. Nucleic Acids Res 2009, 37 Database:D555-559.
-
(2009)
Nucleic Acids Res
, vol.37 Database
-
-
Tweedie, S.1
Ashburner, M.2
Falls, K.3
Leyland, P.4
McQuilton, P.5
Marygold, S.6
Millburn, G.7
Osumi-Sutherland, D.8
Schroeder, A.9
Seal, R.10
-
117
-
-
33646380337
-
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila
-
Pacifico S, Liu G, Guest S, Parrish JR, Fotouhi F, Finley RL. A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila. BMC Bioinformatics 2006, 7:195.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 195
-
-
Pacifico, S.1
Liu, G.2
Guest, S.3
Parrish, J.R.4
Fotouhi, F.5
Finley, R.L.6
-
118
-
-
14844329503
-
A Drosophila protein-interaction map centered on cell-cycle regulators
-
Stanyon CA, Liu G, Mangiola BA, Patel N, Giot L, Kuang B, Zhang H, Zhong J, Finley RL. A Drosophila protein-interaction map centered on cell-cycle regulators. Genome Biol 2004, 5(12):R96.
-
(2004)
Genome Biol
, vol.5
, Issue.12
-
-
Stanyon, C.A.1
Liu, G.2
Mangiola, B.A.3
Patel, N.4
Giot, L.5
Kuang, B.6
Zhang, H.7
Zhong, J.8
Finley, R.L.9
-
119
-
-
20144379646
-
Protein interaction mapping: a Drosophila case study
-
Formstecher E, Aresta S, Collura V, Hamburger A, Meil A, Trehin A, Reverdy C, Betin V, Maire S, Brun C, et al. Protein interaction mapping: a Drosophila case study. Genome Res 2005, 15(3):376-384.
-
(2005)
Genome Res
, vol.15
, Issue.3
, pp. 376-384
-
-
Formstecher, E.1
Aresta, S.2
Collura, V.3
Hamburger, A.4
Meil, A.5
Trehin, A.6
Reverdy, C.7
Betin, V.8
Maire, S.9
Brun, C.10
-
120
-
-
0035212065
-
Is there a bias in proteome research?
-
Mrowka R, Patzak A, Herzel H. Is there a bias in proteome research?. Genome Res 2001, 11(12):1971-1973.
-
(2001)
Genome Res
, vol.11
, Issue.12
, pp. 1971-1973
-
-
Mrowka, R.1
Patzak, A.2
Herzel, H.3
-
121
-
-
0037161731
-
Comparative assessment of large-scale data sets of protein-protein interactions
-
von Mering C, Krause R, Snel B, Cornell M, Oliver SG, Fields S, Bork P. Comparative assessment of large-scale data sets of protein-protein interactions. Nature 2002, 417(6887):399-403.
-
(2002)
Nature
, vol.417
, Issue.6887
, pp. 399-403
-
-
von Mering, C.1
Krause, R.2
Snel, B.3
Cornell, M.4
Oliver, S.G.5
Fields, S.6
Bork, P.7
-
122
-
-
0035235887
-
Two-hybrid system and false positives. Approaches to detection and elimination
-
Serebriiskii IG, Golemis EA. Two-hybrid system and false positives. Approaches to detection and elimination. Methods Mol Biol 2001, 177:123-134.
-
(2001)
Methods Mol Biol
, vol.177
, pp. 123-134
-
-
Serebriiskii, I.G.1
Golemis, E.A.2
-
123
-
-
0037050004
-
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
-
Ho Y, Gruhler A, Heilbut A, Bader GD, Moore L, Adams SL, Millar A, Taylor P, Bennett K, Boutilier K, et al. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 2002, 415(6868):180-183.
-
(2002)
Nature
, vol.415
, Issue.6868
, pp. 180-183
-
-
Ho, Y.1
Gruhler, A.2
Heilbut, A.3
Bader, G.D.4
Moore, L.5
Adams, S.L.6
Millar, A.7
Taylor, P.8
Bennett, K.9
Boutilier, K.10
|