Specificity of short interfering RNA determined through gene expression signatures

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 11, 2003, Pages 6347-6352

  Semizarov, Dimitri ^a   Frost, Leigh ^a   Sarthy, Aparna ^a   Kroeger, Paul ^a   Halbert, Donald N ^a   Fesik, Stephen W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

DNA microarray; Gene knockdown; RNA interference

Indexed keywords

DOUBLE STRANDED RNA; SHORT INTERFERING RIBONUCLEOSIDE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA FINGERPRINTING; DNA MICROARRAY; DRUG TARGETING; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KNOCKOUT GENE; PHENOTYPE; PRIORITY JOURNAL; VALIDATION PROCESS;

GENE EXPRESSION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 0038121109     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1131959100     Document Type: Article

References (35)

1. McManus, M. T. & Sharp, P. A. (2002) Nat. Rev. Genet. 10, 737-747.
2. Caplen, N. J., Parrish, S., Imani, F., Fire, A. & Morgan, R. (2001) Proc. Natl. Acad. Sci. USA 98, 9742-9747.
3. McManus, M., Haines, B., Dillon, C. P., Whitehurst, C. E., van Parijs, L., Chen, J. & Sharp, P. A. (2002) J. Immunol. 169, 5754-5760.
4. Prasanth, S. G., Prasanth, K. V. & Stillman, B. (2002) Science 297, 1026-1031.
5. DiTullio, R. A., Mochan, T. A., Venere, M., Bartkova, J., Sehested, M., Bartek, J. & Halazonetis, T. D. (2002) Nat. Cell Biol. 4, 998-1002.
6. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K. & Tuschl, T. (2001) Nature 411, 494-498.
7. Zou, X., Ray, D., Aziyu, A., Christov, K., Boiko, A. D., Gudkov, A. V. & Kiyokawa, H. (2002) Genes Dev. 15, 2923-2934.
8. Novina, C. D., Murray, M. F., Dykxhoorn, D. M., Beresford, P. J., Riess, J., Lee, S.-K., Collman, R. G., Lieberman, J., Shankar, P. & Sharp, P. (2002) Nat. Med. 8, 659-660.
9. Song, E., Lee, S. K., Wang, J., Ince, N., Ouyang, N., Min, J., Chen, J., Shankar, P. & Lieberman, J. (2003) Nat. Med. 9, 347-351.
10. Elbashir, S. M., Lendeckel, W. & Tuschl, T. (2001) Genes Dev. 15, 188-200.
11. Sharp, P. A. (2001) Genes Dev. 15, 485-490.
12. Zamore, P. (2001) Nat. Struct. Biol. 8, 746-750.
13. Bernstein, E., Denli, A. M. & Hannon, G. J. (2001) RNA 7, 1509-1521.
14. Elbashir, S. M., Martinez, J., Patkaniowska, A., Lendeckel, W. & Tuschl, T. (2001) EMBO J. 20, 6877-6888.
15. Bruckner, I. & Tremblay, G. A. (2000) Biochemistry 39, 11463-11466.
16. Branch, A. D. (1998) Trends Biochem. Sci. 23, 45-50.
17. Lebedeva, I. & Stein, C. A. (2001) Annu. Rev. Pharmacol. Toxicol. 41, 403-419.
18. Stein, C. A. (1995) Nat. Med. 1, 1119-1121.
19. Fisher, A. A., Ye, D., Sergueev, D. S., Fisher, M. H., Shaw, B. R. & Juliano, R. L. (2002) J. Biol. Chem. 277, 22980-22984.
20. Cho, Y. S., Kim, M.-K., Cheadle, C., Neary, C., Becker, K. G. & Cho-Chung, Y. S. (2001) Proc. Natl. Acad. Sci. USA 98, 9819-9823.
21. Shi, H., Hoffman, B. & Lis, J. T. (1999) Proc. Natl. Acad. Sci. USA 96,10033-10038.
22. Ramaswamy, S., Tamayo, P., Rifkin, R., Mukherjee, S., Yeang, C.-H., Angelo, M., Ladd, C., Reich, M., Latulippe, E., Mesirov, J. P., et al. (2001) Proc. Natl. Acad. Sci. USA 98, 15149-15154.
23. Van't Veer, L. J., Dai, H., van de Vijver, M. J., He, Y. D., Hart, A. A. M., Mao, M., Peterse, H. L., van der Kooy, K., Marton, M. J., Witteveen, A. T., et al. (2002) Nature 415, 530-536.
24. Bittner, M., Meltzer, P., Chen, Y., Jiang, Y., Seftor, E., Hendrix, M., Radmacher, M., Simon, R., Yakhini, Z., Ben-Dor, A., et al. (2000) Nature 406, 536-540.
25. Pruitt, K. & Maglott, D, R. (2001) Nucleic Acids Res. 21, 137-140.
26. Xia, T., SantaLucia, J., Jr., Burkard, M. E., Kierzek, R., Schroeder, S. J., Jiao, X., Cox, C. & Turner, D. H. (1998) Biochemistry 37, 14719-14735.
27. Doench, J. G., Petersen, C. P. & Sharp, P. A. (2003) Genes Dev. 17, 438-442.
28. Harborth, J., Elbashir, S., Bechert, K., Tuschl, T. & Weber, K. (2001) J. Cell Sci. 114, 4557-4565.
29. Polager, S., Kalma, Y., Berkovich, E. & Ginsberg, D. (2002) Oncogene 21, 437-446.
30. Kalma, Y., Marash, L., Lamed, Y. & Ginsberg, D. (2001) Oncogene 20, 1379-1387.
31. Song, Y.-J. & Stinski, M. (2002) Proc. Natl. Acad. Sci. USA 99, 2836-2841.
32. Harbour, J. W. & Dean, D. C. (2000) Nat. Cell Biol. 2, E65-E67.
33. Sellers, W. R. & Kaelin, W. G., Jr. (1997) J. Clin. Oncol. 3, 1145-1149.
34. Crooke, S. T. (1999) Biochim. Biophys. Acta 1489, 31-44.
35. Schwarz, D., Hutvagner, G., Haley, B. & Zamore, P. (2002) Mol. Cell 10, 537-548,