Minimizing the risk of reporting false positives in large-scale RNAi screens

Nature Methods

Volumn 3, Issue 10, 2006, Pages 777-779

  Echeverri, Christophe J ^a   Beachy, Philip A ^b   Baum, Buzz ^c   Boutros, Michael ^d   Buchholz, Frank ^e   Chanda, Sumit K ^f   Downward, Julian ^g   Ellenberg, Jan ^h   Fraser, Andrew G ⁱ   Hacohen, Nir ^j,k   Hahn, William C ^j,l   Jackson, Aimee L ^m   Kiger, Amy ⁿ   Linsley, Peter S ^m   Lum, Lawrence ^o   Ma, Yong ^b   Mathey Prévôt, Bernard ^p   Root, David E ^h   Sabatini, David M ^h,q   Taipale, Jussi ^r   Perrimon, Norbert ^p   Bernards, René ^s   more..

^a Cenix BioScience GmbH   (Germany)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^f GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^g IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^h EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

ⁱ WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^j BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^k MASSACHUSETTS GENERAL HOSPITAL   (United States)

^l DANA FARBER CANCER INSTITUTE   (United States)

^m ROSETTA INPHARMATICS   (United States)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^p HARVARD MEDICAL SCHOOL   (United States)

^q WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^r UNIVERSITY OF HELSINKI   (Finland)

^s NETHERLANDS CANCER INSTITUTE   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ACCURACY; ARTICLE; CAENORHABDITIS ELEGANS; DATA ANALYSIS; DROSOPHILA MELANOGASTER; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENE SILENCING; GENETIC DATABASE; GENETIC SCREENING; INFORMATION PROCESSING; INTERPERSONAL COMMUNICATION; MAMMAL CELL; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; RISK REDUCTION; RNA ANALYSIS; RNA INTERFERENCE; RNA SEQUENCE; STANDARD; TRINUCLEOTIDE REPEAT;

DATABASES, GENETIC; FALSE POSITIVE REACTIONS; GENETIC SCREENING; PHENOTYPE; RISK; RNA INTERFERENCE; SENSITIVITY AND SPECIFICITY;

EID: 33749023011     PISSN: 15487091     EISSN: 15491676     Source Type: Journal    
DOI: 10.1038/nmeth1006-777     Document Type: Article

References (7)

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