A cyclin-dependent kinase inhibitor, dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis

Cell

Volumn 87, Issue 7, 1996, Pages 1237-1247

  De Nooij, Joriene C ^a   Letendre, Mary Ann ^a   Hariharan, Iswar K ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; DACAPO PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; ENZYME INHIBITION; EYE DEVELOPMENT; GENE EXPRESSION REGULATION; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

EID: 0030473888     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81819-X     Document Type: Article

References (48)

1. Bier, E., Vaessin, H., Shepherd, S., Lee, K., McCall, K., Barbel, S., Ackerman, L., Carretto, R., Uemura, T., Grell, E., et al. (1989). Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. Genes Dev. 3, 1273-1287.
2. Bodmer, R., Carretto, R., and Jan, Y.N. (1989). Neurogenesis of the peripheral nervous system in Drosophila embryos: DNA replication patterns and cell lineages. Neuron 3, 21-32.
3. Brugarolas, J., Chandrasekaran, C., Gordon, J.I., Beach, D., Jacks, T., and Hannon, G.J. (1995). Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377, 552-557.
4. Campos-Ortega, J.A. (1993). Early neurogenesis in Drosophila melanogaster. In The Development of Drosophila melanogaster, M. Bate and A. Martinez Arias, eds. (Cold Spring Harbor: Cold Spring Harbor Press), pp. 149-300.
5. CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82, 675-684.
6. de Nooij, J.C., and Hariharan, I.K. (1995). Uncoupling cell fate determination from patterned cell division in the Drosophila eye. Science 270, 983-985.
7. Du, W., Vidal, M., Xie, J.-E., and Dyson, N. (1996). RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev. 10, 1206-1218.
8. Dynlacht, B.D., Brook, A., Dembski, M., Yenush, L., and Dyson, N. (1994). DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc. Natl. Acad. Sci. USA 91, 6359-6363.
9. Edgar, B.A., and O'Farrell, P.H. (1989). Genetic control of cell division patterns in the Drosophila embryo. Cell 57, 177-183.
10. Edgar, B.A., and O'Farrell, P.H. (1990). The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string. Cell 62, 469-480.
11. Fero, M.L., Rivkin, M., Tasch, M., Porter, P., Carow, C.E., Firpo, E., Polyak, K., Tsai, L.-H., Broudy, V., Perlmutter, R.M., et al. (1996). A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kip1 -deficient mice. Cell 85, 733-744.
12. Foe, V.E. (1989). Mitotic domains reveal early commitment of cells in Drosophila embryos. Development 107, 1-22.
13. Foe, V.A., Odell, G.M., and Edgar, B. (1993). Mitosis and morphogenesis in the Drosophila embryo: point and counterpoint. In The Development of Drosophila melanogaster, M. Bate and A. Martinez Arias, eds. (Cold Spring Harbor: Cold Spring Harbor Press), pp. 149-300.
14. Hafen, E., Basler, K., Edstroem, J.E., and Rubin, G.M. (1987). Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science 236, 55-63.
15. Hariharan, I.K., Carthew, R.W., and Rubin, G.M. (1991). The Drosophila Roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination. Cell 67, 717-722.
16. Hartenstein, V., and Campos-Ortega, J.A. (1985). Fate mapping in wild-type Drosophila melanogaster. I. The spatio-temporal pattern of embryonic cell divisions. Roux's Arch. Dev. Biol. 196, 473-485.
17. Hay, B.A., Wolff, T., and Rubin, G.M. (1994). Expression of baculovirus p35 prevents cell death in Drosophila. Development 120, 2121-2129.
18. Hortsch, M., Bieber, A.J., Patel, N.H., and Goodman, C.S. (1990). Differential splicing generates a nervous system-specific form of Drosophila neuroglian. Neuron 4, 697-709.
19. Kip1. Cell 85, 721-732.
20. Knoblich, J.A., Sauer, K., Jones, L., Richardson, H., Saint, R., and Lehner, C.F. (1994). Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell 77, 107-120.
21. Lane, M.E., Saeur, K., Wallace, K., Jan, Y.N., Lehner, C.F., and Vaessin, H. (1996). Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosphila development. Cell, this issue.
22. Lee, M.-H., Reynisdottir, I., and Massague, J. (1995). Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique structure and tissue distribution. Genes Dev. 9, 639-649.
23. Lehner, C.F., Yakubovich, N., and O'Farrell, P.H. (1991). Exploring the role of Drosophila cyclin A in the regulation of S-phase. Cold. Spring Harbor Symp. Quant. Biol. 56, 465-475.
24. CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev. 9, 650-662.
25. Murray, A., and Hunt, T. (1993). The Cell Cycle: an Introduction (New York: W. H. Freeman).
26. Mlodzik, M., Hiromi, Y., Weber, U., Goodman, C.S., and Rubin, G.M. (1990). The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates. Cell 60, 211-224.
27. Nakanishi, M., Robetorye, R.S., Adami, G.R., Pereira-Smith, O.M., and Smith, J.R. (1995). Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/CIP1/WAF1. EMBO J. 14, 555-563.
28. Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85, 707-720.
29. O'Brien, M.A., Roberts, M.S., and Taghert, P.H. (1994). A genetic and molecular analysis of the 46C chromosomal region surrounding the FMRFamide neuropeptide gene in Drosophila melanogaster. Genetics 137, 121-137.
30. Patel, N.H. (1994). Imaging neuronal subsets and other cell types in whole-mount Drosophila embryos and larvae using antibody probes. In Drosophila melanogaster: Practical Ises in Cell and Molecular Biology, L.S.B. Goldstein and E.A. Fyrberg, eds. (San Diego: Academic Press, Inc.), pp. 445-487.
31. Patel, N.H., Snow, P.M., and Goodman, C.S. (1987). Characterization and cloning of fasciclin III: a glycoprotein expressed on subsets of neurons and axon pathways in Drosophila. Cell 48, 975-988.
32. Peter, M., Gartner, A., Horecka, J., Ammerer, G., and Herskowitz, I. (1993). FAR1 links the signal transduction pathway to the cell cycle machinery. Cell 73, 747-760.
33. Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extra-cellular antimitogenic signals. Cell 78, 59-66.
34. Prokop, A., and Technau, G.M. (1991). The origin of postembryonic neuroblasts in the ventral nerve cord of Drosophila melanogaster. Development 111, 79-88.
35. Richardson, H.E., O'Keefe, L.V., Reed, S.I., and Saint, R. (1993). A Drosophila G1-specific cyclin E homolog exhibits different modes of expression during embryogenesis. Development 119, 673-690.
36. Richardson, H., O'Keefe, L.V., Marty, T., and Saint, R. (1995). Ectopic cyclin E expression induces premature entry into S phase and disrupts pattern formation in the Drosophila eye imaginai disc. Development 121, 3371-3379.
37. Robinow, S., and White, K. (1991). Characterization and spatial distribution of the ELAV protein during Drosophila melanogaster development. J. Neurobiol. 22, 443-461.
38. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory).
39. Serrano, M., Hannon, G.J., and Beach, D. (1993). A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/ cdk4. Nature 366, 704-707.
40. 1 cyclin-dependent kinases. Genes Dev. 9, 1149-1163.
41. Spradling, A.C., Stern, D.M., Kiss, I., Roote, J., Laverty, T., and Rubin, G.M. (1995). Gene disruptions using P transposable elements: an integral component of the Drosophila genome project. Proc. Natl. Acad. Sci. USA 92, 10824-10830.
42. Tautz, D., and Pfeifle, C. (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
43. Tomlinson, A., and Ready, D.F. (1987a). Cell fate in the Drosophila ommatidium. Dev. Biol. 120, 264-275.
44. Tomlinson, A., and Ready, D.F. (1987b). Neuronal differentiation in the Drosophila ommatidium. Dev. Biol. 120, 366-376.
45. Toyoshima, H., and Hunter, T. (1994). p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity is related to p21. Cell 78, 67-74.
46. Williamson, A., and Lehmann, R. (1996). Germ cell development in Drosophila. Annu. Rev. Cell Dev. Biol. 12, 365-391.
47. Xu, T., and Rubin, G.M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
48. CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F. Genes Dev. 9, 1740-1752.