Prevalence of off-target effects in Drosophila RNA interference screens

Nature

Volumn 443, Issue 7109, 2006, Pages 359-363

  Ma, Yong ^a   Creanga, Adrian ^a,c   Lum, Lawrence ^a,b   Beachy, Philip A ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; CELL CULTURE; CELLS; CYTOLOGY; GENES; PROBABILITY;

DOUBLE-STRANDED RNAS (DSRNA); RNA INTERFERENCE (RNAI); WINGLESS (WG) SIGNAL TRANSDUCTION;

RNA;

DOUBLE STRANDED RNA; MESSENGER RNA; NUCLEOTIDE; SMALL INTERFERING RNA;

ANIMAL; FLY; GENE EXPRESSION; GENOME; HOMOLOGY; PLANT; RNA;

ANIMAL CELL; ARTICLE; BASE MISPAIRING; BASE PAIRING; CONTROLLED STUDY; DROSOPHILA; GENE EXPRESSION; GENE FUNCTION; GENOME; MAMMAL; NONHUMAN; NUCLEOTIDE SEQUENCE; OFF TARGET EFFECT; PRIORITY JOURNAL; RELIABILITY; REPORTER GENE; RNA INTERFERENCE; RNA PROCESSING; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRINUCLEOTIDE REPEAT; WINGLESS GENE;

ANIMALIA; MAMMALIA;

EID: 33748939584     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05179     Document Type: Article

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