A Map of the Interactome Network of the Metazoan C. elegans

Science

Volumn 303, Issue 5657, 2004, Pages 540-543

  Li, Siming ^a   Armstrong, Christopher M ^a   Bertin, Nicolas ^a   Ge, Hui ^a   Milstein, Stuart ^a   Boxem, Mike ^a   Vidalain, Pierre Olivier ^a   Han, Jing Dong J ^a   Chesneau, Alban ^a,b   Hao, Tong ^a   Goldberg, Debra S ^a   Li, Ning ^a   Martinez, Monica ^a   Rual, Jean François ^a,c   Lamesch, Philippe ^a,c   Xu, Lai ^a,d   Tewari, Muneesh ^a   Wong, Sharyl L ^a   Zhang, Lan V ^a   Berriz, Gabriel F ^a   Jacotot, Laurent ^a,l   Vaglio, Philippe ^a,l   Reboul, Jérôme ^a,m   Hirozane Kishikawa, Tomoko ^a   Li, Qianru ^a   Gabel, Harrison W ^a   Elewa, Ahmed ^a,n   Baumgartner, Bridget ^d   Rose, Debra J ^e   Yu, Haiyuan ^f   Bosak, Stephanie ^g   Sequerra, Reynaldo ^g   Fraser, Andrew ^h   Mango, Susan E ⁱ   Saxton, William M ^e   Strome, Susan ^e   Van Den Heuvel, Sander ^j   Piano, Fabio ^k   Vandenhaute, Jean ^c   Sardet, Claude ^b   Gerstein, Mark ^f   Doucette Stamm, Lynn ^g   Gunsalus, Kristin C ^k   Harper, J Wade ^a,d   Cusick, Michael E ^a   Roth, Frederick P ^a   Hill, David E ^a,o   Vidal, Marc ^a,o   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b CNRS   (France)

^c Lab d'Immunol microbiologie   (Belgium)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e INDIANA UNIVERSITY   (United States)

^f YALE UNIVERSITY   (United States)

^g Agencourt Bioscience Corporation   (United States)

^h WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

ⁱ UNIVERSITY OF UTAH   (United States)

^j MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^k NEW YORK UNIVERSITY   (United States)

^l Modul Bio   (France)

^m INSTITUT PAOLI CALMETTES   (France)

ⁿ UNIVERSITY OF MASSACHUSETTS   (United States)

^o DANA FARBER CANCER INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; YEAST;

PROTEIN-PROTEIN INTERACTIONS;

PROTEINS;

BIOLOGY; PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; CELL FUNCTION; COMPUTER MODEL; METAZOON; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PURIFICATION; QUALITY CONTROL; VALIDATION PROCESS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; COMPUTATIONAL BIOLOGY; EVOLUTION, MOLECULAR; GENES, HELMINTH; GENOMICS; OPEN READING FRAMES; PHENOTYPE; PROTEIN BINDING; PROTEOME; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; INVERTEBRATA; METAZOA; NEMATODA;

EID: 9144264169     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1091403     Document Type: Article

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29. We thank members of M.V.'s laboratory for their input and help; C. Boone, G. Achaz and D. Allinger for discussions; the sequencing staff at Agencourt Biosciences for technical assistance; the ORFeome meeting participants for their input; C. McCowan, T. Clingingsmith, and C. You for administrative assistance; and C. Fraughton for laboratory support. This work was supported by a grant from NHGRI and NIGMS awarded to M.V. Other support includes an NSF award (K.C.G.); NIGMS grants (S.v.d.H., S.E.M., J.W.H.); a Department of Defense Predoctoral Fellowship (B.B.); an award from the Ligue Nationale Contre Le Cancer (équipe labelisée) (C.S., A.C.); an institutional HHMI grant (F.P.R., G.F.B); and Fellowships from EMBO (P.-O.V.), NSF (D.S.G), Ryan, Milton (S.L.W.), Fu (L.V.Z.), and Leukemia Research Foundation (M.E.).