Bioactive compounds in mango (Mangifera indica L.)

Bioactive Foods in Promoting Health

Volumn , Issue , 2010, Pages 507-523

  Ribeiro, Sônia Machado Rocha ^a   Schieber, Andreas ^b  

^a FEDERAL UNIVERSITY OF VIÇOSA   (Brazil)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Antioxidant Capacity; Bioactive Compounds; Functional Potential; Mangoes; Nutritional Value

Indexed keywords

EID: 79955388868     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374628-3.00034-7     Document Type: Chapter

References (133)

1. Mukherjee S.K. Introduction: Botany and importance. The mango, production and uses 1997, CAB International, Oxon, UK. R.E. Litz (Ed.).
2. The mango, production and uses 1997, CAB International, Oxon, UK. R.E. Litz (Ed.).
3. FAOSTAT. (2007). FAO Statistical Database - Agriculture.. Accessed November 8, 2007. http://www.faostat.fao.org.
4. Ramteke R.S., Vilajayalaskshmi M.R., Eipeson W.E. Processing and value addition to mangoes. Indian Food Industry 1999, 18:155-163.
5. Sauco G.V. Mango production and world market: Current situation and future prospects. Acta Horticulturae 2004, 645:107-116.
6. Scrinis G. Functional foods or functionally marketed foods? A critique of, and alternative to, the category of 'functional foods'. Public Health Nutrition 2008, 11:541-545.
7. Arogba S.S. Physical, chemical and functional properties of Nigerian mango (Mangifera indica) kernel and its processed flour. Journal of the Science of Food and Agriculture 1997, 73:321-328.
8. Dhingra S., Kapoor A.C. Nutritive value of mango seed kernel. Journal of the Science of Food and Agriculture 1985, 36:752-756.
9. Abdalla A.E.M., Darwish S.M., Ayad E.H.E., El-Hamahmy R.M. Egyptian mango by-product 1. compositional quality of mango seed kernel. Food Chemistry 2007, 103:1134-1140.
10. Garg N., Tandon D.K. Amylase activity of A. oryzae grown on mango kernel after certain treatments and aeration. Indian Food Packer 1997, 51:26-29.
11. Rukmini C., Vijayaraghavan M. Nutritional and toxicological evaluation of mango kernel oil. Journal of the American Oil Chemists'Society 1984, 61:789-792.
12. Mahattanatawee K., Manthey J.A., Luzio G., Talcott S.T., Goodner K., Baldwin E.A. Total antioxidant activity and fiber content of select Florida-grown tropical fruits. Journal of Agricultural and Food Chemistry 2006, 54:7355-7363.
13. Larrauri J.A., Rupérez P., Borroto B., Saura-Calixto F. Mango peels as a new tropical fibre: Preparation and characterization. Lebensmittel-Wissenschaft und -Technologie 1996, 29:729-733.
14. Berardini N., Knödler M., Schieber A., Carle R. Utilization of mango peels as a source of pectin and polyphenolics. Innovative Food Science and Emerging Technologies 2005, 6:443-453.
15. Sirisakulwat S., Nagel A., Sruamsiri P., Carle R., Neidhart S. Yield and quality of pectins extractable from the peels of Thai mango cultivars depending on fruit ripeness. Journal of Agricultural and Food Chemistry 2008, 56:10727-10738.
16. Ribeiro, S. M. R. (2006). Mango (Mangifera indica, L.) Antioxidant Potential of mangoes: Characterization and Evaluation. Thesis (Doctor Science) - Federal University of Viçosa, Viçosa, Brazil.
17. Leterme P., Buldgen A., Estrada F., Londoño A.M. Mineral content of tropical fruits and unconventional foods of the Andes and the rain forest of Colombia. Food Chemistry 2006, 95:644-652.
18. Mercandante A.Z., Rodriguez-Amaya D.B. Effects of ripening, cultivar differences, and processing on the carotenoid composition of mango. Journal of Agricultural and Food Chemistry 1998, 46:128-130.
19. +)-MS]. Journal of Agricultural and Food Chemistry 2007, 55:6628-6635.
20. WHO (World Health Organization) (1995). Global prevalence of vitamin A deficiency: micronutrient deficiency information system; Working Paper 2. WHO, Geneva (Document WHO/NUT/95.3).
21. Veda S., Platel K., Srinivasan K. Varietal differences in the bioaccessibility of ?-carotene from mango (Mangifera indica) and papaya (Carica papaya) fruits. Journal of Agricultural and Food Chemistry 2007, 55:7931-7935.
22. Ribeiro S.M.R., Queiroz J.H., Lopes M.E.L.R., Milagres F.C., Pinheiro-Sant'Ana H.M. Antioxidant in mango (Mangifera indica L) pulp. Plant Foods for Human Nutrition 2007, 62:13-17.
23. Corral-Aguayo R.D., Yahia E.M., Carrilo-Lopez A., González-Aguilar G. Correlation between some nutritional components and the total antioxidant capacity measured with six different assays in eight horticultural crops. Journal of Agricultural and Food Chemistry 2008, 56:10498-10504.
24. Nagy S. Vitamin C contents of citrus and their products: A review. Journal of Agricultural and Food Chemistry 1980, 28:8-18.
25. Miller N., Rice-Evans C.A. The relative contributions of ascorbic acid and phenolic antioxidants to the antioxidant activity of orange and apple fruit juices and blackcurrant drink. Food Chemistry 1997, 60:331-337.
26. Ross I.A. Medicinal plants of the world: Chemical constituents, traditional medicinal uses 2003, pp. 315-328, Humana Press Inc, Totowa, NJ.
27. Pardo-Andreu G.L., Dorta D.J., Delgado R., Cavalheiro R.A., Santos A.S., Vercesi A.E., Curti C. Vimang (Mangifera indica L. extract) induces permeability transition in isolated mitochondria, closely reproducing the effect of mangiferin, Vimang's main component. Chemico-Biological Interactions 2006, 159:141-148.
28. Lima Z.P., Severi J.A., Pellizon C.H., Brito A.R.M.S., Solis P.N., Cáceres A., Girón L.M., Hiruma-Lima C.A. Can the aqueous decoction of mango flowers be used as an antiulcer agent?. Journal of Ethnopharmacology 2006, 106:29-37.
29. Rahuman A.A., Bagavan A., Kamaraj C., Vadivelu M., Zahir A.A., Elango G., Pandiyan G. Evaluation of indigenous plant extracts against larvae of Culex quinquefasciatus Saty (Diptera: Culicidae). Parasitology Research 2008, 104:637-643.
30. Rodeiro I., Donato M.T., Lahoz A., González-Lavaut, Laguna A., Castell J.V., Delgado R., Gómez-Lechón M.J. Modulation of P450 enzymes by Cuban natural products rich in polyphenolic compounds in rat hepatocytes. Chemico-Biological Interactions 2008, 172:1-10.
31. Parmar H.S., Kar A. Protective role of Mangifera indica, Cucumis melo and Citrullus vulgaris peel extracts in chemically induced hypothyroidism. Chemico-Biological Interactions 2008, 177:254-258.
32. Saito N.K., Kohno M., Yoshizazaki F., Niwano K. Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions. Plant Foods for Human Nutrition 2008, 63:65-70.
33. 4, anti-chemotaxic action in leucocyte rolling. Chemico-Biological Interactions 2009, 179:344-350.
34. Block G., Patterson B., Subar A. Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence. Nutrition and Cancer 1992, 18:1-29.
35. Ames B.M., Shigenaga M.K., Hagwn T.M. Oxidants, antioxidants and the degenerative diseases of aging. Proceedings of the National Academy of Sciences of the United States of America 1993, 90:7915-7922.
36. Linster C.L., Van Shaftingen E. Vitamin C. Biosynthesis, recycling and degradation in mammals. FEBS Journal 2007, 274:1-22.
37. Lee S.K., Kader A. Preharvest and postharvest factors influencing vitamin C content of horticultural crops. Postharvest Biology and Technology 2000, 20:207-220.
38. Franke A.A., Custer L.J., Araraki C., Murphy S.P. Vitamin C and flavonoid levels of fruits and vegetables consumed in Hawaii. Journal of Food Composition and Analysis 2004, 17:1-35.
39. Nisperos-Carriedo M.O., Buslig B.S., Shaw P.E. Simultaneous detection of dehydroascorbic, ascorbic, and some organic acids in fruits and vegetables by HPLC. Journal of Agricultural and Food Chemistry 1992, 40:1127-1130.
40. Vinci G., Botré F., Mele G., Ruggieri G. Ascorbic acid in exotic fruits: A liquid chromatographic investigation. Food Chemistry 1995, 53:211-214.
41. Reys L.F., Cisneros-Zevallos L. Electron-beam ionizing radiation stress effects on mango fruit (Mangifera indica L.) antioxidant constituents before and during postharvest storage. Journal of Agricultural and Food Chemistry 2007, 55:6132-6139.
42. Gil M.I., Aguayo E., Kader A.A. Quality changes and nutrient retention in fresh-cut versus whole fruits during storage. Journal of Agricultural and Food Chemistry 2006, 54:4284-4296.
43. Buettner G.R. The pecking order of free radicals and antioxidants: Lipid peroxidation, alpha-tocopherol, and ascorbate. Archives of Biochemistry and Biophysics 1993, 300:534-543.
44. Weber P., Bendich A., Schalch W. Vitamin C and human health - a review of a recent data relevant to requirements. International Journal for Vitamin and Nutrition Research 1996, 66:19-30.
45. Tannenbauen S.R., Wishnok J.S., Leaf C.D. Inhibition of nitrosamine formation by ascorbic acid. American Journal of Clinical Nutrition 1991, 53(Suppl. 1):2475-2505.
46. Nordberg J., Arnér E.S.J. Reactive oxygen species antioxidants, and the mammalian thioredoxin system. Free Radical Biology and Medicine 2001, 31:1287-1312.
47. Block G., Jensen C.D., Norkus E.P., Hudes M., Crawford P.B. Vitamin C in plasma is inversely related to blood pressure and change in blood pressure during the previous year in young black and white women. Nutrition Journal 2008, 7:37-39.
48. Loria C.M., Klag M.J., Cauldield L.E., Whelton P.K. Low vitamin C status may increase the risk of mortality from cancer and cardiovascular disease. American Journal of Clinical Nutrition 2000, 72:139-145.
49. Jenabi M., Riboli E., Ferrari P., Sabate J., Slimani N., Nora T., et al. Plasma and dietary vitamin C levels and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Carcinogenesis 2006, 27:2250-2257.
50. Halliwell B. Vitamin C and genomic stability. Mutation Research 2001, 475:29-35.
51. Godoy H.T., Rodriguez-Amaya D.B. Carotenoid composition of commercial mangoes from Brazil. Lebensmittel-Wissenschaft und -Technologie 1989, 22:100-103.
52. Chen J.P., Tai C.Y., Chen B.H. Improved liquid chromatographic method for determination of carotenoids in Taiwanese mango (Mangifera indica). Journal of Chromatography A 2004, 1054:261-268.
53. Pott I., Breithaupt D.E., Carle R. Detection of unusual carotenoid esters in fresh mango (Mangifera indica L. cv. 'Kent'). Phytochemistry 2003, 64:825-829.
54. Mercadante A.Z., Rodriguez-Amaya D.B., Britton G. HPLC and mass spectrometric analysis of carotenoids from mango. Journal of Agricultural and Food Chemistry 1997, 45:120-123.
55. Hulshof P.J.M., Xu C., Van De Bovenkamp P., Muhital, West C.E. Application of a validated method for determination of provitamin A carotenoids in Indonesian foods of different maturity and origin. Journal of Agricultural and Food Chemistry 1997, 45:1147-1179.
56. Ben-Amotz A., Fishler R. Analysis of carotenoids with emphasis on 9-cis-?-carotene in vegetables and fruits commonly consumed in Israel. Food Chemistry 1998, 62:515-520.
57. Setiawan B., Sulaeman A., Giraud D.W., Driskell J.A. Carotenoid content of selected Indonesian fruits. Journal of Food Composition and Analysis 2001, 14:169-176.
58. Lutz C., Navakoudis E., Seidlitz H.K., Kotzabasis K. Stimulated solar irradiation with enhanced UV-B plastid-and thylakoid-associated polyamine changes for UV-B protection. Biochimica Biophysica Acta 2005, 1710:24-33.
59. Thurnham D.I. Carotenoids: Functions and fallacies. The Proceedings of the Nutrition Society 1994, 53:77-87.
60. IOM (1998). Food and Nutrition Board. Dietary reference intakes: proposed definition and plan for review of dietary antioxidants and related compounds. Published: August 5, 1998. Available at:. Accessed: May 15, 2002. http://www.nap.edu.
61. Krinsky N. Carotenoids as antioxidants. Nutrition 2001, 17:815-817.
62. Chambon P.A. A decade of molecular biology of retinoic acid receptors. FASEB Journal 1996, 10:940-943.
63. Burri J.B. Carotenoids and gene expression. Nutrition 2000, 16:7-8.
64. Rao A.V., Rao L.G. Carotenoids and human health. Pharmacological Research 2007, 55:207-216.
65. Lauretani F., Semba R.D., Bandinelli S., Dayhoff-Brannigan M., Lauretani F., Corsi A.M., Guralnik J.M., Ferrucci L. Carotenoids as protection against disability in older persons. Rejuvenation Research 2008, 11:557-563.
66. El Ansari M.A., Reddy K.K., Sastry K.N.S., Nayudamma Y. Polyphenols of Mangifera indica. Phytochemistry 1971, 10:2239-2241.
67. Schieber A., Ulrich W., Carle R. Characterization of polyphenols in mango puree concentrate by HPLC with diode array and mass spectrometric detection. Innovative Food Science and Emerging Technologies 2001, 1:161-166.
68. Schieber A., Berardini N., Carle R. Identification of flavonol and xanthone glycosides from mango (Mangifera indica L. Cv. 'Tommy Atkins') peels by high-performance liquid chromatography-electrospray ionization mass spectrometry. Journal of Agricultural and Food Chemistry 2003, 51:5006-5011.
69. Berardini N., Schieber A., Klaiber I., Beifuss U., Carle R., Conrad J. 7-O-Methylcyanidin 3-O-?-D-galactopyranoside, a novel anthocyanin from mango (Mangifera indica L. cv. 'Tommy Atkins') peels. Zeitschrift für Naturforschung 2005, 60b:801-804.
70. Ribeiro S.M.R., Barbosa L.C.A., Queiroz J.H., Knödler M., Schieber A. Phenolic compounds and antioxidant capacity of Brazilian mango (Mangifera indica L.) varieties. Food Chemistry 2008, 110:620-628.
71. Berardini N., Fezer R., Conrad J., Beifuss U., Carle R., Schieber A. Screening of mango (Mangifera indica L.) cultivars for their contents of flavonol O- and xanthone C-glycosides, anthocyanins, and pectin. Journal of Agricultural and Food Chemistry 2005, 53:1563-1570.
72. Barreto J.C., Trevisan M.T.S., Hull W.E., Erben G., de Brito E.S., Pfundstein B., Würtele G., Spiegelhalder B., Owen R.W. Characterization and quantification of polyphenolic compounds in bark, kernel, leaves, and peel of mango. Journal of Agricultural and Food Chemistry 2008, 56:5599-5610.
73. Middleton E., Kandaswami C., Theoharides T.C. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacological Reviews 2000, 52:673-751.
74. Knekt P., Kumpulainen J., Järvinen R., Rissanen H., Heliövaara M., Reunanen A., Hakulinen T., Haromaa A. Flavonoid intake and risk of chronic diseases. American Journal of Clinical Nutrition 2002, 76:560-568.
75. Knouhouser M.L. Review: Dietary flavonoids and cancer risk: Evidence from human population studies. Nutrition and Cancer 2004, 50:1-7.
76. Paganga G., Miller N., Rice-Evans C.A. The polyphenolic content of fruit and vegetables and their antioxidant activities. What does a serving constitute?. Free Radical Research 1999, 30:153-162.
77. Rice-Evans C.A., Miller N.J., Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology and Medicine 1996, 20:933-956.
78. Moskaug J.Ø., Carlsen H., Myhrstad M., BlomhoffR. Molecular imaging of the biological effects of quercetin and quercetin-rich foods. Mechanisms of Ageing and Development 2004, 125:315-324.
79. Ansari A.A., Abdul H.M., Joshi G., Opii W.O., Butterfield A. Protective effect of quercetin in primary neurons against A ?(1-42): relevance to Alzheimer's disease. Journal of Nutritional Biochemistry 2009, 20:269-275.
80. Cao G., Sofic E., Prior R. Antioxidant and prooxidant behaviour of flavonoids: structure-activity relationships. Free Radical Biology and Medicine 1997, 22:749-760.
81. Sanchéz G.M., Re L., Giulian A., Núñez-Sellés A.J., Davison G.P., Léon-Fernández O.S. Protective effects of Mangifera indica L. extract, mangiferin and selected antioxidants against TPA-induced biomolecules oxidation and peritoneal macrophage activation in mice. Pharmacological Research 2000, 42:565-573.
82. Yoshimi N., Matsunaga K., Katayama M., Yamada Y., Kuno T., Qiao Z., Hara A., Yamahara J., Mori H. The inhibitory effects of mangiferin, a naturally occurring glucosylxanthone, in bowel carcinogenesis of male F344 rats. Cancer Letters 2001, 163:163-170.
83. Muruganandan S., Gupta S., Kataria M., Lal J., Gupta P.K. Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats. Toxicology 2002, 176:165-173.
84. Leiro J.M., álvarez E., Arranz J.A., Siso I.G., Orallo F. In vitro effects of mangiferin on superoxide concentrations and expression of the inducible nitric oxide synthase, tumor necrosis factor-? and transforming growth factor-? genes. Biochemical Pharmacology 2003, 65:1361-1371.
85. Leiro J., Arranz J.A., Yáñez M., Ubeira F.M., Sanmartin M.L., Orallo F. Expression profiles of genes involved in the mouse nuclear factor-kappa B signal transduction pathway are modulated by mangiferin. International Immunopharmacology 2004, 4:763-778.
86. Jagetia G., Venkatesha V. Mangiferin protects human peripheral blood lymphocytes against ?-radiation-induced DNA strand breaks: A fluorescence analysis of DNA unwinding assay. Nutrition Research 2006, 26:303-311.
87. Rajendran P., Ekambaram G., Sakthisekaran D. Effect of mangiferin on benzo(a)pyrene induced lung carcinogenesis in experimental Swiss albino mice. Natural Product Research 2008, 22:672-680.
88. Rodriguez J., Di Pierro D., Gioia M., Monaco S., Delgado R., Coletta M., Marini S. Effects of a natural extract from Mangifera indica L., and its active compound mangiferin, on state and lipid peroxidation of red blood cells. Biochimica et Biophysica Acta 2006, 1760:1333-1342.
89. Wilkinson A.S., Monbteich G.R., Shaw P.N., Lin C.N., Gidley M.J., Roberts-Thomson S.J. Effects of the mango components mangiferin and quercetin and the putative mangiferin metabolite norathyriol on the transactivation of peroxisome proliferator-activated receptor isoforms. Journal of Agricultural and Food Chemistry 2008, 56:3037-3042.
90. Bhatia H.S., Candelario-Jalil E., Oliveira A.C., Olajide O.A., Martínez-Sanchez G., Fiebich B.L. Mangiferin inhibits cycloxygenase-2 expression and prostaglandin E (2) production in activated rat microglia cells. Archives of Biochemistry and Biophysics 2008, 477:253-258.
91. Carvalho A.C., Guedes M.M., Souza A.L., Trevisan M.T., Lima A.F., Santos F.A., Rao V.S. Gastroprotective effect of mangiferin a xanthonoid from Mangifera indica, aginst gastric injury induced by ethanol and indomethacin in rodents. Planta Medica 2007, 73:1372-1376.
92. Singh V.K. Physiological and biochemical changes with special reference to mangiferin and oxidative enzymes level in malformation resistant and susceptible cultivars of mango (Mangifera indica L.). Scientia Horticulturae 2006, 108:43-48.
93. Knödler M., Berardini N., Kammerer D.R., Carle R., Schieber A. Characterization of major and minor alk(en)ylresorcinols from mango (Mangifera indica L.) peels by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. Rapid Communications in Mass Spectrometry 2007, 21:945-951.
94. Cojocaru M., Droby S., Glotter E., Goldman A., Gottlier H.E., Jacoby B., Prusky D. (12-Heptadecenyl)-resorcinol, the major component of the antifungal activity in the peel of mango fruit. Phytochemistry 1986, 25:1093-1095.
95. Knödler M., Conrad J., Wenzig E.M., Bauer R., Lacorn M., Beifuss V., Carle R., Schieber A. Anti-inflammatory 5-(11Z-heptadecenyl)- and 5-(8Z, 11Z-heptadecadienyl)-resorcinols from mango (Mangifera indica L.) peels. Phytochemistry 2008, 69:988-993.
96. Dang K.T.H., Singh Z., Swinny E.E. Edible coatings influence fruit ripening quality, and aroma biosynthesis in mango fruit. Journal of Agricultural and Food Chemistry 2008, 56:1361-1370.
97. Andrade E.H.A., Maia J.G.S., Zoghbi M.G.B. Aroma volatile constituents of Brazilian varieties of mango fruit. Journal of Food Composition and Analysis 2000, 13:27-33.
98. Sagar S.P., Chidley H.G., Kulkarni R.S., Pujari K.H., Giri A.P., Gupta V.S. Cultivar relationships in mango based on fruit volatile profiles. Food Chemistry 2009, 114:363-372.
99. Jhon K.S., Bhat S.G., Rao U.J.S.P. Biochemical characterization of sap (latex) of a few Indian mango varieties. Phytochemistry 2003, 62:13-19.
100. Pino J.A., Mesa J., Muñoz Y., Matí M.P., Mabbot R. Volatile components from mango (Mangifera indica L.) cultivars. Journal of Agricultural and Food Chemistry 2005, 53:2213-2223.
101. Lalel H.J.D., Singh Z., Tan S.C. Aroma volatiles production during fruit ripening of 'Kensington Pride' mango. Postharvest Biology and Technology 2003, 27:323-336.
102. Lalel H.J.D., Singh Z., Tan S.C. Distribution of aroma volatile compounds in different parts of mango fruit. Journal of Horticultural Science & Biotechnology 2003, 78:131-138.
103. Lalel H.J.D., Singh Z., Tan S.C. Glycosidically-bound aroma volatile compounds in the skin and pulp of 'Kensington Pride' mango fruit at different stages of maturity. Postharvest Biology and Technology 2003, 29:205-218.
104. Lalel H.J.D., Singh Z., Tan S.C. Maturity stage at harvest affects fruit ripening, quality and biosynthesis of aroma volatile compounds in 'Kensington Pride' mango. Journal of Horticultural Science & Biotechnology 2003, 78:225-233.
105. Lalel H.J.D., Singh Z., Tan S.C. Ripening temperatures influence biosynthesis of aroma volatiles compounds in 'Kensington Pride' mango fruit. Journal of Horticultural Science & Biotechnology 2004, 79:146-157.
106. Bardon S., Picard K., Martel P. Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1, gene expression in human breast cancer cell lines. Nutrition and Cancer 1998, 32:1-7.
107. Crowell P.L. Prevention and therapy of cancer by dietary monoterpenes. The Journal of Nutrition 1999, 129:775-778.
108. Foti M.C., Ingold K.U. Mechanism of inhibition of lipid peroxidation by gamma-terpinene, an unusual and potentially useful hydrocarbon antioxidant. Journal of Agricultural and Food Chemistry 2003, 51:2758-2765.
109. Hwang Y.P., Jeong H.G. The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress. FEBS Letters 2008, 582:2655-2662.
110. Grassmann J. Terpenoids as plant antioxidants. Vitamins and Hormones 2005, 72:5005-5535.
111. Rabi T., Gupta S. Dietary terpenoids and prostate cancer chemoprevention. Frontiers in Bioscience 2008, 13:3457-3469.
112. Prasad S., Kabra N., Shukla Y. Induction of apoptosis by lupeol and mango extract in mouse prostate and LNCaP cells. Nutrition and Cancer 2008, 60:120-130.
113. Chaturvedi P.K., Bhui K., Shukla Y. Lupeol: Connotations for chemoprevention. Cancer Letters 2008, 263:1-13.
114. Sudhahar V., Veena C.K., Varalakshmi P. Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. Journal of Natural Products 2008, 71:1509-1512.
115. Gibson G.R., Roberfroid M. Dietary modulation of human colonic microbiota: Introducing the concept of prebiotics. The Journal of Nutrition 1995, 125:1401-1412.
116. Brown L., Rosner B., Willet W.W., Sacks F.M. Cholesterol-lowering effects of dietary fiber: A meta-analysis. American Journal of Clinical Nutrition 1999, 69:30-42.
117. Umar S., Morris A.P., Korouma F., Sellin J.H. Dietary pectin and calcium inhibit colonic proliferation in vivo by differing mechanisms. Cell Proliferation 2003, 36:361-375.
118. Jenkins D.J., Leeds A.R., Gassul M.A., Cochet B., Albert G.M. Decrease in post prandial insulin and glucose concentrations by guar and pectin. Annals of Internal Medicine 1977, 86:20-23.
119. Kim M. High-methoxyl pectin has greater enhancing effect on glucose uptake in intestinal perfused rats. Nutrition 2005, 21:372-377.
120. Pirman T., Mosoni L., Ramond D., Ribeyre M.C., Buffière C., Salobir J., Mirand P.P. Differential response of protein metabolism in splanchnic organs and muscle to pectin feeding. The British Journal of Nutrition 2008, 100:306-311.
121. Larrauri J.A., Rupérez P., Saura-Calixto F. Mango peels as new tropical fiber: Obtention and characterization. Lebensmittel-Wissenschaft und -Technologie 1995, 29:729-733.
122. Prasanna V., Prabha T.N., Tharanathan R.N. Pectic polysaccharides of mango (Mangifera indica L.): Structural studies. Journal of the Science of Food and Agriculture 2004, 84:1731-1735.
123. Núñez-Selléz A.J., Rodríguez M.D.D., Balseiro E.R., Gonzalez L.N., Nicolais V., Rastrelli L. Comparison of major and trace elements concentrations in 16 varieties of Cuban mango stem bark (Mangifera indica L.). Journal of Agricultural and Food Chemistry 2007, 55:2176-2181.
124. Halliwell B. Antioxidant defense mechanisms: From the beginning to the end (of the beginning). Free Radical Research 1999, 31:261-272.
125. Zhou B., Wu L., Yang L., Liu Z. Evidence for ?-tocopherol regeneration reaction of green tea polyphenols in SDS micelles. Free Radical Biology and Medicine 2005, 38:78-84.
126. Brighenti F., Valtuena S., Pellegrini N. Total antioxidant capacity of the diet is inversely and independently related to plasma concentration of high-sensitivity C-reactive protein in adult Italian subjects. The British Journal of Nutrition 2005, 93:619-625.
127. Valtueña S., Pellegrini N., Franzini L., Bianchi M.A., Ardigo D., Del Rio D., Piatti P.M., Scazzina F., Zavaroni I., Brighenti F. Food selection based on total antioxidant capacity can modify antioxidant intake, systemic inflammation, and liver function without altering markers of oxidative stress. American Journal of Clinical Nutrition 2008, 87:1290-1297.
128. Ajila C.M., Naidu K.A., Bhat S.G., Prasada Rao U.J.S. Bioactive compounds and antioxidant potential of mango peel extract. Food Chemistry 2007, 105:982-988.
129. Ajila M., Naidu K.A., Bhat S.G., Prasada Rao U.J.S. Valuable components of raw and ripe peels from two Indian mango varieties. Food Chemistry 2007, 102:1006-1011.
130. Abdalla A.E.M., Darwish S.M., Ayad E.H.E., El-Hamahmy R.M. Egyptian mango by-product 2: Antioxidant and antimicrobial activities of extract and oil from mango seed kernel. Food Chemistry 2006, 103:1141-1152.
131. Amimoto T., Matsura T., Koyama S., Nakanish T., Yamada K., Kajiyama G. Acetaminophen-induced hepatic injury in mice: The role of lipid peroxidation and effects of pretreatment with coenzyme Q10 and ?-tocopherol. Free Radical Biology and Medicine 1995, 19:169-176.
132. Paschke A., Kinder H., Zunker K., Wigotzki M., Wessbecher R., Viluf I., Steinhart H. Charactrization of cross-reaction allergens in mango fruit. Allergy 2001, 56:237-242.
133. Dube M., Zunker K., Neidhart S., Carle R., Steinhart H., Paschke A. Effect of technological processing on the allergenicity of mangoes (Mangifera indica L.). Journal of Agricultural and Food Chemistry 2004, 52:3938-3945.