Protective role of Mangifera indica, Cucumis melo and Citrullus vulgaris peel extracts in chemically induced hypothyroidism

Chemico-Biological Interactions

Volumn 177, Issue 3, 2009, Pages 254-258

  Parmar, Hamendra Singh ^a   Kar, Anand ^a  

^a DEVI AHILYA UNIVERSITY   (India)

Author keywords

Citrullus vulgaris; Cucumis melo; Hypothyroidism; Lipid peroxidation; Mangifera indica; Thyroid hormones

Indexed keywords

AMYLASE; CUCUMIS MELO EXTRACT; GLUCOSE; INSULIN; LIOTHYRONINE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MANGIFERA INDICA EXTRACT; PLANT EXTRACT; PROPYLTHIOURACIL; THYROXINE; UNCLASSIFIED DRUG; WATERMELON EXTRACT;

AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANTALOUPE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HISTOPATHOLOGY; HYPOTHYROIDISM; INSULIN BLOOD LEVEL; LIOTHYRONINE BLOOD LEVEL; LIPID BLOOD LEVEL; LIPID METABOLISM; LIPID PEROXIDATION; MALE; NONHUMAN; RAT; THYROXINE BLOOD LEVEL; WATERMELON; WISTAR RAT;

ANIMALS; ANTITHYROID AGENTS; CITRULLUS; CUCUMIS MELO; HYPOTHYROIDISM; LIPID PEROXIDATION; MALE; MANGIFERA; PLANT EXTRACTS; PROPYLTHIOURACIL; RATS; RATS, WISTAR;

ANIMALIA; CITRULLUS LANATUS VAR. LANATUS; CUCUMIS MELO; MANGIFERA INDICA; RATTUS;

EID: 58349119164     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.11.006     Document Type: Article

References (50)

1. Bohm H., Boeing H., Hempel J., Raab B., and Kroke A. Flavonols, flavone and anthocyanins as natural antioxidants of food and their possible role in the prevention of chronic diseases. Z. Ernahrungswiss. 37 (1998) 147-163
2. Higashi-Okai K., Kamimoto K., Yoshioka A., and Okai Y. Potent suppressive activity of fresh and dried peels from Satsuma mandarin (Citrus unshiu Marcorv.) on hydroperoxide generation from oxidized linoleic acid. Phytother. Res. 16 (2002) 781-784
3. Leontowicz M., Gorinstein S., Leontowicz H., Krzeminski R., Lojek A., Katrich E., Ciz M., Martin-Belloso O., Soliva-Fortuny R., Haruenkit R., and Trakhtenberg S. Apple and pear peel and pulp and their influence on plasma lipids and antioxidant potentials in rats fed cholesterol-containing diets. J. Agric. Food Chem. 51 (2003) 5780-5785
4. Anagnostopoulou M.A., Kefalas P., Kokkalou E., Assimopoulou A.N., and Papageorgiou V.P. Analysis of antioxidant compounds in sweet orange peel by HPLC-diode array detection-electrospray ionization mass spectrometry. Biomed. Chromatogr. 19 (2005) 138-148
5. Hakim I.A., Harris R.B., and Ritenbaugh C. Citrus peel use is associated with reduced risk of squamous cell carcinoma of the skin. Nutr. Cancer 37 (2000) 161-168
6. Murakami A., Nakamura Y., Ohto Y., Yano M., Koshiba T., Koshimizu K., Tokuda H., Nishino H., and Ohishi H. Suppressive effects of citrus fruits on free radical generation and nobiletin, an anti-inflammatory polymethoxylated flavonoid. Biofactors 12 (2000) 187-192
7. Chidambara-Murthy K.N., Jayaprakash G.K., and Singh R.P. Studies on antioxidant activity of pomegranate (Punica granatum) peel extract using in vivo models. J. Agric. Food Chem. 50 (2002) 4791-4795
8. Singh R.P., Chidambara Murthy K.N., and Jayaprakash G.K. Studies on the antioxidant activity of pomegranate (Punica granatum) peel and seed extracts using in vitro models. J. Agric. Food Chem. 50 (2002) 81-86
9. Parish M.E., Baum D., Kryger R., Good rich R., and Baum R. Fate of salmonellae in citrus oils and aqueous aroma. J. Food Prot. 66 (2003) 1704-1707
10. Parmar H.S., and Kar A. Protective role of Citrus sinensis, Musa paradisiaca, and Punica granatum against diet-induced atherosclerosis and thyroid dysfunctions in rats. Nutr. Res. 27 (2007) 710-718
11. Zinchenko T.V., Minlin M.Z., and Prokopovich N.N. Anthelmintic properties of Cucumis melo seeds. Farmakol. Toksikol. 18 (1955) 41-43
12. Singh R.C., and Sisodia C.S. Pharmacodynamic investigations into the diuretic activity of Cucumis melo seed (ether extract). Ind. J. Med. Res. 58 (1970) 505-512
13. Malhotra O.P., and Rani I. Occurrence, isolation & characterization of urease-inhibitor from melon (Cucumis melo) seeds. Ind. J. Biochem. Biophys. 15 (1978) 229-231
14. Altman R., Rouvier J., and Weisenberger H. Identification of platelet inhibitor present in the melon (Cucurbitacea cucumis melo). Thromb. Haemost. 53 (1985) 312-313
15. Vouldoukis I., Lacan D., Kamate C., Coste P., Calenda A., Mazier D., Conti M., and Dugas B. Antioxidant and anti-inflammatory properties of a Cucumis melo LC. extract rich in superoxide dismutase activity. J. Ethnopharmacol. 94 (2004) 67-75
16. Naito Y., Akagiri S., Uchiyama K., Kokura S., Yoshida N., Hasegawa G., Nakamura N., Ichikawa H., Toyokuni S., Ijichi T., and Yoshikawa T. Reduction of diabetes-induced renal oxidative stress by cantaloupe melon extract/gliadin biopolymers, oxykine, in mice. Biofactors 23 (2005) 85-95
17. Rimando A.M., and Perkins-Veazie P.M. Determination of citrulline in watermelon rind. J. Chromatogr. A 1078 (2005) 196-200
18. Castillo L., Sanchez M., Vogt J., Chapman T.E., De Rojas-Walker T.C., Tannenbaun S.R., Ajami A.M., and Young V.R. Plasma arginine, citrulline, and ornithine kinetics in adults, with observations on nitric oxide synthesis. Am. J. Physiol. 268 (1995) E360-E367
19. Collins J.K., Wu G., Perkins-Veazie P., Spears K., Claypool P.L., Baker R.A., and Clevidence B.A. Watermelon consumption increases plasma arginine concentration in adults. Nutrition 23 (2007) 261-266
20. Rodríguez J., Di Pierro D., Gioia M., Monaco S., Delgado R., Coletta M., and Marini S. Effects of a natural extract from Mangifera indica L., and its active compound, mangiferin, on energy state and lipid peroxidation of red blood cells. Biochim. Biophys. Acta 1760 (2006) 1333-1342
21. Rocha Ribeiro S.M., Queiroz J.H., Lopes Ribeiro de Queiroz M.E., Campos F.M., and Pinheiro Sant'ana H.M. Antioxidant in mango (Mangifera indica L.) pulp. Plants Hum. Nutr. 62 (2007) 13-17
22. Sá-Nunes A., Rogerio A.P., Medeiros A.I., Fabris V.E., Andreu G.P., Rivera D.G., Delgado R., and Faccioli L.H. Modulation of eosinophil generation and migration by Mangifera indica L. extract (Vimang). Int. Immunopharmacol. 6 (2006) 1515-1523
23. Hernandez P., Rodriguez P.C., Delgado R., and Walczak H. Protective effect of Mangifera indica L. polyphenols on human T lymphocytes against activation-induced cell death. Pharmacol. Res. 55 (2007) 167-173
24. Rivera D.G., Balmaseda I.H., León A.A., Hernández B.C., Montiel L.M., Garrido G.G., Cuzzocrea S., and Hernández R.D. Anti-allergic properties of Mangifera indica L. extract (Vimang) and contribution of its glucosylxanthone mangiferin. J. Pharm. Pharmacol. 58 (2006) 385-392
25. Prabhu S., Jainu M., Sabitha K.E., and Shyamala Devi C.S. Effect of mangiferin on mitochondrial energy production in experimentally induced myocardial infracted rats. Vascul. Pharmacol. 44 (2006) 519-525
26. Percival S.S., Talcott S.T., Chin S.T., Mallak A.C., Lounds-Singleton A., and Pettit-Moore J. Neoplastic transformation of BALB/3T3 cells and cell cycle of HL-60 cells are inhibited by mango (Mangifera indica L.) juice and mango juice extracts. J. Nutr. 136 (2006) 1300-1304
27. Sánchez G.M., Rodríguez H.M.A., Giuliani A., Núñez Sellés A.J., Rodríguez N.P., Leo'n Fernandez O.S., and Re L. Protective effect of Mangifera indica L. extract (Vimang) on the injury associated with hepatic ischaemia reperfusion. Phytother. Res. 17 (2003) 197-201
28. Prasad S., Kalra N., and Shukla Y. Hepatoprotective effects of lupeol and mango pulp extract of carcinogen induced alteration in Swiss albino mice. Mol. Nutr. Food Res. 51 (2007) 352-359
29. Núñez-Sellés A.J., Delgado-Hernández R., Garrido-Garrido G., García-Rivera D., Guevara-García M., and Pardo-Andreu G.L. The paradox of natural products as pharmaceuticals. Experimental evidences of a mango stem bark extract. Pharmacol. Res. 55 (2007) 351-358
30. Sellés A.J., Rodríguez M.D., Balseiro E.R., Gonzalez L.N., Nicolais V., and Rastrelli L. Comparison of major and trace element concentrations in 16 varieties of Cuban mango stem bark (Mangifera indica L.). J. Agric. Food Chem. 55 (2007) 2176-2181
31. Parmar H.S., and Kar A. Antiperoxidative, antithyroidal, antihyperglycemic and cardioprotective role of Citrus sinensis peel extracts in male mice. Phytother. Res. 22 (2008) 791-795
32. Parmar H.S., and Kar A. Medicinal values of fruit peels from Citrus sinensis, Punica granatum and Musa paradisiaca with respect to alterations in tissue lipid peroxidation and serum concentration of glucose, insulin and thyroid hormones. J. Med. Food 11 (2008) 376-381
33. Parmar H.S., and Kar A. Antidiabetic potential of Citrus sinensis and Punica granatum peel extracts in alloxan treated male mice. Biofactors 31 (2007) 17-24
34. Kirby J.D., Jetton A.E., Cooke P.S., Hess R.A., Bunick D., Ackland J.F., Turek F.W., and Schwartz N.B. Developmental hormonal profiles accompanying the neonatal hypothyroidism-induced increase in adult testicular size and sperm production in the rat. Endocrinology 131 (1992) 559-565
35. Sener G., Kabasakal L., Atasoy B.M., Erzik C., Velioǧlu-Oǧünç A., Cetinel S., Contuk G., Gedik N., and Yeǧen B.C. Propylthiouracil-induced hypothyroidism protects ionizing radiation-induced multiple organ damage in rats. J. Endocrinol. 189 (2006) 257-269
36. Trinder P. Determination of blood glucose using an oxidase-peroxidase system with non-carcinogenic chromogen. J. Clin. Pathol. 22 (1969) 158-161
37. Jatwa R., and Kar A. Cardio-protective role of terazosin is possibly mediated through alteration in thyroid function. Eur. J. Pharmacol. 551 (2006) 87-91
38. Parmar H.S., and Kar A. Atherogenic diet induced diabetes mellitus: involvement of thyroid hormones. Eur. J. Pharmacol. 570 (2007) 244-248
39. Allain C.C., Poon L.S., Chan C.S., Richmond W., and Fu P.C. Enzymatic determination of total serum cholesterol. Clin. Chem. 20 (1974) 470-475
40. Fossati P., and Lorenzo P. Serum triglycerides determination colorimetrically with an enzyme that produces hydrogen peroxide. Clin. Chem. 28 (1982) 2077-2080
41. Ranson J.H. Acute pancreatitis. Curr. Probl. Surg. 16 (1979) 1-84
42. Friedwald W.T., Levy R.I., and Fredrickson D.C. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin. Chem. 18 (1972) 499-502
43. Parmar H.S., Panda S., Jatwa R., and Kar A. Cardioprotective role of Terminalia arjuna bark extract is possibly mediated through alterations in thyroid hormones. Pharmazie 61 (2006) 793-795
44. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin-phenol reagent. J. Biol. Chem. 193 (1951) 265-275
45. Lauberg P. Mechanism governing the relative proportion of thyroxine and 3,5,3′-triiodothyronine in thyroid secretion. Metabolism 33 (1984) 379-392
46. Panda S., and Kar A. Evaluation of the antithyroid, antioxidative and hyperglycemia activity of Scopoletin from Aegle marmelos leaves in hyperthyroid rats. Phytother. Res. 20 (2006) 1103-1105
47. Auf'mkolk M., Kohrle J., Gumbinger H., Winterhoff H., and Hesch R.D. Antihormonal effects of plant extracts: iodothyronine deiodinase of rat liver in inhibited by extracts and secondary metabolites of plants. Horm. Metab. Res. 16 (1984) 188-192
48. Kar A., and Panda S. Ayurvedic therapies for thyroid dysfunction. In: Mishra L. (Ed). Scientific Basis of Ayurvedic Therapies (2004), CRC Press, USA (Chapter 8)
49. Duntas L.H. Thyroid disease and lipids. Thyroid 12 (2002) 287-293
50. Pinelo M., Manzocco L., Nunez M.J., and Nicoli M.C. Interaction among phenols in food fortification: negative synergism on antioxidant capacity. J. Agric. Food Chem. 52 (2004) 1177-1180