-
1
-
-
33745115304
-
P53 and breast cancer, an update
-
DOI 10.1677/erc.1.01172
-
M Lacroix, RA Toillon and G Leclercq: p53 and breast cancer, an update. Endocr Relat Cancer 13(2), 293-325 (2006) (Pubitemid 43886660)
-
(2006)
Endocrine-Related Cancer
, vol.13
, Issue.2
, pp. 293-325
-
-
Lacroix, M.1
Toillon, R.-A.2
Leclercq, G.3
-
2
-
-
33745713432
-
P53 and metabolism: Inside the TIGAR
-
DR Green and JE Chipuk: p53 and metabolism: Inside the TIGAR. Cell 126(1), 30-2 (2006)
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 30-32
-
-
Green, D.R.1
Chipuk, J.E.2
-
3
-
-
0036258111
-
The IARC TP53 database: New online mutation analysis and recommendations to users
-
DOI 10.1002/humu.10081
-
M Olivier, R Eeles, M Hollstein, MA Khan, CC Harris and P Hainaut: The IARC TP53 database: new online mutation analysis and recommendations to users. Hum Mutat 19(6), 607-14 (2002) (Pubitemid 34556481)
-
(2002)
Human Mutation
, vol.19
, Issue.6
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
4
-
-
0031918223
-
BCL-2 family: Regulators of cell death
-
DOI 10.1146/annurev.immunol.16.1.395
-
D Chao and S Korsmeyer: BCL-2 family: regulators of cell death. Annu Rev Immunol 16, 395-419 (1998) (Pubitemid 28183370)
-
(1998)
Annual Review of Immunology
, vol.16
, pp. 395-419
-
-
Chao, D.T.1
Korsmeyer, S.J.2
-
5
-
-
0242410719
-
P53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa
-
DOI 10.1126/science.1090072
-
A Villunger, EM Michalak, L Coultas, F Mullauer, G Bock, M J Ausserlechner, JM Adams and A Strasser: p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302(5647), 1036-8 (2003) (Pubitemid 37386194)
-
(2003)
Science
, vol.302
, Issue.5647
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Bock, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
6
-
-
0028070989
-
P53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
-
DOI 10.1038/370220a0
-
C Caelles, A Helmberg and M Karin: p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370(6486), 220-3 (1994) (Pubitemid 24236778)
-
(1994)
Nature
, vol.370
, Issue.6486
, pp. 220-223
-
-
Caelles, C.1
Helmberg, A.2
Karin, M.3
-
7
-
-
0029092356
-
Induction of apoptosis in HeLa cells by transactivation-deficient p53
-
Y Haupt, S Rowan, E Shaulian, KH Vousden and M Oren: Induction of apoptosis in HeLa cells by transactivation-deficient p53. Genes Dev 9(17), 2170-83 (1995)
-
(1995)
Genes Dev
, vol.9
, Issue.17
, pp. 2170-2183
-
-
Haupt, Y.1
Rowan, S.2
Shaulian, E.3
Vousden, K.H.4
Oren, M.5
-
8
-
-
0034523818
-
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
-
DOI 10.1038/sj.cdd.4400783
-
SJ Korsmeyer, MC Wei, M Saito, S Weiler, KJ Oh and PH Schlesinger: Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 7(12), 1166-73 (2000) (Pubitemid 32042223)
-
(2000)
Cell Death and Differentiation
, vol.7
, Issue.12
, pp. 1166-1173
-
-
Korsmeyer, S.J.1
Wei, M.C.2
Saito, M.3
Weiler, S.4
Oh, K.J.5
Schlesinger, P.H.6
-
9
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
-
E Yang, J Zha, J Jockel, LH Boise, CB Thompson and SJ Korsmeyer: Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80(2), 285-91 (1995)
-
(1995)
Cell
, vol.80
, Issue.2
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
-
10
-
-
0034786019
-
L sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
DOI 10.1016/S1097-2765(01)00320-3
-
EH Cheng, MC Wei, S Weiler, RA Flavell, TW Mak, T Lindsten and SJ Korsmeyer: BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX-and BAKmediated mitochondrial apoptosis. Mol Cell 8(3), 705-11 (2001) (Pubitemid 32946946)
-
(2001)
Molecular Cell
, vol.8
, Issue.3
, pp. 705-711
-
-
Cheng, E.H.-Y.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
11
-
-
85006263913
-
BID regulation by p53 contributes to chemosensitivity
-
DOI 10.1038/ncb866
-
JK Sax, P Fei, ME Murphy, E Bernhard, SJ Korsmeyer and WS El-Deiry: BID regulation by p53 contributes to chemosensitivity. Nat Cell Biol 4(11), 842-9 (2002) (Pubitemid 35331358)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.11
, pp. 842-849
-
-
Sax, J.K.1
Fei, P.2
Murphy, M.E.3
Bernhard, E.4
Korsmeyer, S.J.5
El-Deiry, W.S.6
-
12
-
-
41149152733
-
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
-
J Chipuk and D Green: How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol 18(4), 157-64 (2008)
-
(2008)
Trends Cell Biol
, vol.18
, Issue.4
, pp. 157-164
-
-
Chipuk, J.1
Green, D.2
-
14
-
-
0030916669
-
The proto-oncogene Bcl-2 and its role in regulating apoptosis
-
DOI 10.1038/nm0697-614
-
G Kroemer: The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3(6), 614-20 (1997) (Pubitemid 27264969)
-
(1997)
Nature Medicine
, vol.3
, Issue.6
, pp. 614-620
-
-
Kroemer, G.1
-
15
-
-
21844464054
-
Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis
-
DOI 10.1038/sj.emboj.7600675
-
MG Annis, EL Soucie, PJ Dlugosz, JA Cruz-Aguado, LZ Penn, B Leber and DW Andrews: Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis. EMBO J 24(12), 2096-103 (2005) (Pubitemid 40961794)
-
(2005)
EMBO Journal
, vol.24
, Issue.12
, pp. 2096-2103
-
-
Annis, M.G.1
Soucie, E.L.2
Dlugosz, P.J.3
Cruz-Aguado, J.A.4
Penn, L.Z.5
Leber, B.6
Andrews, D.W.7
-
16
-
-
33745755472
-
Bcl-2 changes conformation to inhibit Bax oligomerization
-
DOI 10.1038/sj.emboj.7601126, PII 7601126
-
PJ Dlugosz, LP Billen, MG Annis, W Zhu, Z Zhang, J Lin, B Leber and DW Andrews: Bcl-2 changes conformation to inhibit Bax oligomerization. EMBO J 25(11), 2287-96 (2006) (Pubitemid 44012212)
-
(2006)
EMBO Journal
, vol.25
, Issue.11
, pp. 2287-2296
-
-
Dlugosz, P.J.1
Billen, L.P.2
Annis, M.G.3
Zhu, W.4
Zhang, Z.5
Lin, J.6
Leber, B.7
Andrews, D.W.8
-
17
-
-
0025204548
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
D Hockenbery, G Nunez, C Milliman, RD Schreiber and SJ Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348(6299), 334-6 (1990) (Pubitemid 120029101)
-
(1990)
Nature
, vol.348
, Issue.6299
, pp. 334-336
-
-
Hockenbery, D.1
Ninez, G.2
Milliman, C.3
Schreiber, R.D.4
Korsmeyer, S.J.5
-
18
-
-
0033580219
-
Bcl-2 overexpression results in reciprocal downregulation of Bcl-X(L) and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosis
-
EL Arriola, AM Rodriguez-Lopez, JA Hickman and CM Chresta: Bcl-2 overexpression results in reciprocal downregulation of Bcl-X(L) and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosis. Oncogene 18(7), 1457-64 (1999) (Pubitemid 29103633)
-
(1999)
Oncogene
, vol.18
, Issue.7
, pp. 1457-1464
-
-
Arriola, E.L.1
Rodriguez-Lopez, A.M.2
Hickman, J.A.3
Chresta, C.M.4
-
19
-
-
0030805125
-
Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases
-
O Olopade, M Adeyanju, A Safa, F Hagos, R Mick, C Thompson and W Recant: Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases. Cancer J Sci Am 3(4), 230-7 (1997)
-
(1997)
Cancer J Sci Am
, vol.3
, Issue.4
, pp. 230-237
-
-
Olopade, O.1
Adeyanju, M.2
Safa, A.3
Hagos, F.4
Mick, R.5
Thompson, C.6
Recant, W.7
-
20
-
-
0031706315
-
P53 and bcl-2 protein expression in non-small-cell lung carcinoma
-
DOI 10.1002/(SICI)1097-0339(199810)19:4<255::AID-DC5>3.0.CO;2-9
-
P Athanassiadou, T Dosios, E Petrakakou, A Liossi, C Zerva and P Athanassiades: p53 and bcl-2 protein expression in non-small-cell lung carcinoma. Diagn Cytopathol 19(4), 255-9 (1998) (Pubitemid 28440074)
-
(1998)
Diagnostic Cytopathology
, vol.19
, Issue.4
, pp. 255-259
-
-
Athanassiadou, P.1
Dosios, T.2
Petrakakou, E.3
Liossi, A.4
Zerva, C.5
Athanassiades, P.6
-
21
-
-
0032055936
-
Bcl-2 and apoptosis in lymph node positive breast carcinoma
-
DOI 10.1002/(SICI)1097-0142(19980401)82:7<1296::AID-CNCR12>3.0. CO;2-1
-
MD Berardo, RM Elledge, C de Moor, GM Clark, CK Osborne and DC Allred: bcl-2 and apoptosis in lymph node positive breast carcinoma. Cancer 82(7), 1296-302 (1998) (Pubitemid 28155391)
-
(1998)
Cancer
, vol.82
, Issue.7
, pp. 1296-1302
-
-
Berardo, M.D.1
Elledge, R.M.2
De Moor, C.3
Clark, G.M.4
Osborne, C.K.5
Allred, D.C.6
-
22
-
-
0034655373
-
2 response of normal human fibroblasts
-
DOI 10.1042/0264-6021:3470543
-
QM Chen, J Liu and JB Merrett: Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts. Biochem J 347(Pt 2), 543-51 (2000) (Pubitemid 30229403)
-
(2000)
Biochemical Journal
, vol.347
, Issue.2
, pp. 543-551
-
-
Chen, Q.M.1
Liu, J.2
Merrett, J.B.3
-
23
-
-
0038013875
-
Senescence, apoptosis and therapy - Cutting the lifelines of cancer
-
CA Schmitt: Senescence, apoptosis and therapy-cutting the lifelines of cancer. Nat Rev Cancer 3(4), 286-95 (2003) (Pubitemid 37328864)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.4
, pp. 286-295
-
-
Schmitt, C.A.1
-
24
-
-
0034852080
-
Senescent cells are resistant to death despite low Bcl-2 level
-
DOI 10.1016/S0047-6374(01)00281-0, PII S0047637401002810
-
M Sasaki, T Kumazaki, H Takano, M Nishiyama and Y Mitsui: Senescent cells are resistant to death despite low Bcl-2 level. Mech Ageing Dev 122(15), 1695-706 (2001) (Pubitemid 32835217)
-
(2001)
Mechanisms of Ageing and Development
, vol.122
, Issue.15
, pp. 1695-1706
-
-
Sasaki, M.1
Kumazaki, T.2
Takano, H.3
Nishiyama, M.4
Mitsui, Y.5
-
25
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
DOI 10.1016/S1535-6108(02)00127-7
-
A Letai, MC Bassik, LD Walensky, MD Sorcinelli, S Weiler and SJ Korsmeyer: Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2(3), 183-92 (2002) (Pubitemid 41043974)
-
(2002)
Cancer Cell
, vol.2
, Issue.3
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
26
-
-
0036365079
-
Bax and BH3-domain-only proteins in p53-mediated apoptosis
-
X Wu and Y Deng: Bax and BH3-domain-only proteins in p53-mediated apoptosis. Front Biosci 7, d151-6 (2002)
-
(2002)
Front Biosci
, vol.7
-
-
Wu, X.1
Deng, Y.2
-
27
-
-
0141818136
-
Integral role of Noxa in p53-mediated apoptotic response
-
DOI 10.1101/gad.1103603
-
T Shibue, K Takeda, E Oda, H Tanaka, H Murasawa, A Takaoka, Y Morishita, S Akira, T Taniguchi and N Tanaka: Integral role of Noxa in p53-mediated apoptotic response. Genes Dev. 17(18), 2233-2238 (2003) (Pubitemid 37128638)
-
(2003)
Genes and Development
, vol.17
, Issue.18
, pp. 2233-2238
-
-
Shibue, T.1
Takeda, K.2
Oda, E.3
Tanaka, H.4
Murasawa, H.5
Takaoka, A.6
Morishita, Y.7
Akira, S.8
Taniguchi, T.9
Tanaka, N.10
-
28
-
-
10744228800
-
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
-
DOI 10.1016/S1535-6108(03)00244-7
-
JR Jeffers, E Parganas, Y Lee, C Yang, J Wang, J Brennan, KH MacLean, J Han, T Chittenden, JN Ihle, PJ McKinnon, JL Cleveland and GP Zambetti: Puma is an essential mediator of p53-dependent and-independent apoptotic pathways. Cancer Cell 4(4), 321-8 (2003) (Pubitemid 37329796)
-
(2003)
Cancer Cell
, vol.4
, Issue.4
, pp. 321-328
-
-
Jeffers, J.R.1
Parganas, E.2
Lee, Y.3
Yang, C.4
Wang, J.5
Brennan, J.6
MacLean, K.H.7
Han, J.8
Chittenden, T.9
Ihle, J.N.10
McKinnon, P.J.11
Cleveland, J.L.12
Zambetti, G.P.13
-
29
-
-
0036716281
-
The BCL2 family: Regulators of the cellular life-or-death switch
-
DOI 10.1038/nrc883
-
S Cory and JM Adams: The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2(9), 647-56 (2002) (Pubitemid 37328916)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.9
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
30
-
-
21444432928
-
Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria
-
DOI 10.1074/jbc.M410691200
-
Y Arima, M Nitta, S Kuninaka, D Zhang, T Fujiwara, Y Taya, M Nakao and H Saya: Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria. J Biol Chem 280(19), 19166-76 (2005) (Pubitemid 41379623)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.19
, pp. 19166-19176
-
-
Arima, Y.1
Nitta, M.2
Kuninaka, S.3
Zhang, D.4
Fujiwara, T.5
Taya, Y.6
Nakao, M.7
Saya, H.8
-
31
-
-
0037372005
-
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
-
DOI 10.1038/ng1093
-
P Dumont, JI Leu, AC Della Pietra, 3rd, DL George and M Murphy: The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet 33(3), 357-65 (2003) (Pubitemid 36278852)
-
(2003)
Nature Genetics
, vol.33
, Issue.3
, pp. 357-365
-
-
Dumont, P.1
Leu, J.I.-J.2
Della Pietra III, A.C.3
George, D.L.4
Murphy, M.5
-
32
-
-
3242690522
-
In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
-
DOI 10.1128/MCB.24.15.6728-6741.2004
-
S Erster, M Mihara, RH Kim, O Petrenko and UM Moll: In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol Cell Biol, 24(15), 6728-41 (2004) (Pubitemid 38944352)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.15
, pp. 6728-6741
-
-
Erster, S.1
Mihara, M.2
Kim, R.H.3
Petrenko, O.4
Moll, U.M.5
-
33
-
-
18144421236
-
Stress-induced p53 runs a transcription-independent death program
-
DOI 10.1016/j.bbrc.2005.03.187, Apoptosis Control
-
S Erster and UM Moll: Stress-induced p53 runs a transcription-independent death program. Biochem Biophys Res Commun 331(3), 843-50 (2005) (Pubitemid 40615515)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.331
, Issue.3
, pp. 843-850
-
-
Erster, S.1
Moll, U.M.2
-
34
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria: A potential role in apoptotic signaling
-
DOI 10.1074/jbc.275.21.16202
-
ND Marchenko, A Zaika and UM Moll: Death signalinduced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 275(21), 16202-12 (2000) (Pubitemid 30366932)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.21
, pp. 16202-16212
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
35
-
-
0037349289
-
P53 has a direct apoptogenic role at the mitochondria
-
DOI 10.1016/S1097-2765(03)00050-9
-
M Mihara, S Erster, A Zaika, O Petrenko, T Chittenden, P Pancoska and UM Moll: p53 has a direct apoptogenic role at the mitochondria. Mol Cell 11(3), 577-90 (2003) (Pubitemid 36385115)
-
(2003)
Molecular Cell
, vol.11
, Issue.3
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
36
-
-
0035910385
-
Hypoxia death stimulus induces translocation of p53 protein to mitochondria - Detection by immunofluorescence on whole cells
-
DOI 10.1016/S0014-5793(00)02368-1, PII S0014579300023681
-
C Sansome, A Zaika, ND Marchenko and UM Moll: Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells. FEBS Lett 488(3), 110-5 (2001) (Pubitemid 32103581)
-
(2001)
FEBS Letters
, vol.488
, Issue.3
, pp. 110-115
-
-
Sansome, C.1
Zaika, A.2
Marchenko, N.D.3
Moll, U.M.4
-
37
-
-
27544461103
-
Viral and cellular oncogenes induce rapid mitochondrial translocation of p53 in primary epithelial and endothelial cells early in apoptosis
-
DOI 10.1016/j.febslet.2005.09.074, PII S0014579305011920
-
A Nemajerova, S Wolff, O Petrenko and UM Moll: Viral and cellular oncogenes induce rapid mitochondrial translocation of p53 in primary epithelial and endothelial cells early in apoptosis. FEBS Lett 579(27), 6079-83 (2005) (Pubitemid 41546250)
-
(2005)
FEBS Letters
, vol.579
, Issue.27
, pp. 6079-6083
-
-
Nemajerova, A.1
Wolff, S.2
Petrenko, O.3
Moll, U.M.4
-
38
-
-
27544490654
-
Mitochondrially targeted p53 has tumor suppressor activities in vivo
-
DOI 10.1158/0008-5472.CAN-05-1084
-
F Talos, O Petrenko, P Mena and UM Moll: Mitochondrially targeted p53 has tumor suppressor activities in vivo. Cancer Res 65(21), 9971-81 (2005) (Pubitemid 41541478)
-
(2005)
Cancer Research
, vol.65
, Issue.21
, pp. 9971-9981
-
-
Talos, F.1
Petrenko, O.2
Mena, P.3
Moll, U.M.4
-
39
-
-
27744449741
-
Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis
-
DOI 10.1074/jbc.M502052200
-
F Essmann, S Pohlmann, B Gillissen, PT Daniel, K Schulze-Osthoff and RU Janicke: Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis. J Biol Chem 280(44), 37169-77 (2005) (Pubitemid 41587801)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.44
, pp. 37169-37177
-
-
Essmann, F.1
Pohlmann, S.2
Gillissen, B.3
Daniel, P.T.4
Schulze-Osthoff, K.5
Janicke, R.U.6
-
40
-
-
0842278331
-
Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
-
DOI 10.1126/science.1092734
-
J E Chipuk, T Kuwana, L Bouchier-Hayes, NM Droin, DD Newmeyer, M Schuler and DR Green: Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303(5660), 1010-4 (2004) (Pubitemid 38209704)
-
(2004)
Science
, vol.303
, Issue.5660
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
41
-
-
46749117587
-
P53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity
-
DOI 10.1038/cr.2008.62, PII CR200862
-
S Wolff, S Erster, G Palacios and UM Moll: p53′s mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. Cell Res 18(7), 733-44 (2008) (Pubitemid 351948223)
-
(2008)
Cell Research
, vol.18
, Issue.7
, pp. 733-744
-
-
Wolff, S.1
Erster, S.2
Palacios, G.3
Moll, U.M.4
-
42
-
-
51049086207
-
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
-
EC Pietsch, E Perchiniak, AA Canutescu, G Wang, RL Dunbrack and ME Murphy: Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain. J Biol Chem 283(30), 21294-304 (2008)
-
(2008)
J Biol Chem
, vol.283
, Issue.30
, pp. 21294-21304
-
-
Pietsch, E.C.1
Perchiniak, E.2
Canutescu, A.A.3
Wang, G.4
Dunbrack, R.L.5
Murphy, M.E.6
-
43
-
-
0442323478
-
L-binding interface using NMR
-
DOI 10.1016/S0014-5793(04)00059-6
-
AM Petros, A Gunasekera, N Xu, ET Olejniczak and SW Fesik: Defining the p53 DNA-binding domain/Bclx(L)-binding interface using NMR. FEBS Lett 559(1-3), 171-4 (2004) (Pubitemid 38186723)
-
(2004)
FEBS Letters
, vol.559
, Issue.1-3
, pp. 171-174
-
-
Petros, A.M.1
Gunasekera, A.2
Xu, N.3
Olejniczak, E.T.4
Fesik, S.W.5
-
44
-
-
2342553892
-
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
-
DOI 10.1038/ncb1123
-
JI Leu, P Dumont, M Hafey, ME Murphy and DL George: Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. Nat Cell Biol 6(5), 443-50 (2004) (Pubitemid 38607505)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.5
, pp. 443-450
-
-
Leu, J.I.-J.1
Dumont, P.2
Hafey, M.3
Murphy, M.E.4
George, D.L.5
-
45
-
-
33745017872
-
Bcl2's flexible loop domain regulates p53 binding and survival
-
DOI 10.1128/MCB.01647-05
-
X Deng, F Gao, T Flagg, J Anderson and WS May: Bcl2′s flexible loop domain regulates p53 binding and survival. Mol Cell Biol 26(12), 4421-34 (2006) (Pubitemid 43877564)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.12
, pp. 4421-4434
-
-
Deng, X.1
Gao, F.2
Flagg, T.3
Anderson, J.4
May, W.S.5
-
46
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
DOI 10.1016/S1097-2765(01)00214-3
-
K Nakano and KH Vousden: PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 7(3), 683-94 (2001) (Pubitemid 32706359)
-
(2001)
Molecular Cell
, vol.7
, Issue.3
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
47
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
T Miyashita and JC Reed: Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80(2), 293-9 (1995)
-
(1995)
Cell
, vol.80
, Issue.2
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
48
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
DOI 10.1126/science.288.5468.1053
-
E Oda, R Ohki, H Murasawa, J Nemoto, T Shibue, T Yamashita, T Tokino, T Taniguchi and N Tanaka: Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288(5468), 1053-8 (2000) (Pubitemid 30324238)
-
(2000)
Science
, vol.288
, Issue.5468
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
49
-
-
0028575705
-
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein
-
Y Shen and T Shenk: Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein. Proc Natl Acad Sci U S A 91(19), 8940-4 (1994)
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.19
, pp. 8940-8944
-
-
Shen, Y.1
Shenk, T.2
-
50
-
-
70350025502
-
Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis
-
G Dewson and R Kluck: Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis. J Cell Sci 122(Pt 16), 2801-8 (2009)
-
(2009)
J Cell Sci
, vol.122 PART 16
, pp. 2801-2808
-
-
Dewson, G.1
Kluck, R.2
-
51
-
-
33646826684
-
WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization
-
DOI 10.1074/jbc.M507611200
-
Y Tomita, N Marchenko, S Erster, A Nemajerova, A Dehner, C Klein, H Pan, H Kessler, P Pancoska and UM Moll: WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization. J Biol Chem 281(13), 8600-6 (2006) (Pubitemid 43847963)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.13
, pp. 8600-8606
-
-
Tomita, Y.1
Marchenko, N.2
Erster, S.3
Nemajerova, A.4
Dehner, A.5
Klein, C.6
Pan, H.7
Kessler, H.8
Pancoska, P.9
Moll, U.M.10
-
52
-
-
33847276654
-
Monoubiquitylation promotes mitochondrial p53 translocation
-
ND Marchenko, S Wolff, S Erster, K Becker and UM Moll: Monoubiquitylation promotes mitochondrial p53 translocation. EMBO J 26(4), 923-34 (2007)
-
(2007)
EMBO J
, vol.26
, Issue.4
, pp. 923-934
-
-
Marchenko, N.D.1
Wolff, S.2
Erster, S.3
Becker, K.4
Moll, U.M.5
-
53
-
-
77649190277
-
Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer
-
B Ahn, D Trinh, L Zajchowski, B Lee, A Elwi and S Kim: Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer. Oncogene 29(8), 1155-66 (2010)
-
(2010)
Oncogene
, vol.29
, Issue.8
, pp. 1155-1166
-
-
Ahn, B.1
Trinh, D.2
Zajchowski, L.3
Lee, B.4
Elwi, A.5
Kim, S.6
-
54
-
-
76749114291
-
Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control
-
C Li, Y Cheng, P Liao and J Kang: Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control. Neoplasia 12(2), 150-60 (2010)
-
(2010)
Neoplasia
, vol.12
, Issue.2
, pp. 150-160
-
-
Li, C.1
Cheng, Y.2
Liao, P.3
Kang, J.4
-
55
-
-
66449099052
-
P53 acetylation is crucial for its transcription-independent proapoptotic functions
-
H Yamaguchi, NT Woods, LG Piluso, HH Lee, J Chen, KN Bhalla, A Monteiro, X Liu, MC Hung and HG Wang: p53 acetylation is crucial for its transcription-independent proapoptotic functions. J Biol Chem 284(17), 11171-83 (2009)
-
(2009)
J Biol Chem
, vol.284
, Issue.17
, pp. 11171-11183
-
-
Yamaguchi, H.1
Woods, N.T.2
Piluso, L.G.3
Lee, H.H.4
Chen, J.5
Bhalla, K.N.6
Monteiro, A.7
Liu, X.8
Hung, M.C.9
Wang, H.G.10
-
56
-
-
10744230086
-
MDM4 (MDMX) Overexpression Enhances Stabilization of Stress-induced p53, and Promotes Apoptosis
-
DOI 10.1074/jbc.M311793200
-
F Mancini, F Gentiletti, M D'Angelo, S Giglio, S Nanni, C D'Angelo, A Farsetti, G Citro, A Sacchi, A Pontecorvi and F Moretti: MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosis. J Biol Chem 279(9), 8169-80 (2004) (Pubitemid 38294708)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.9
, pp. 8169-8180
-
-
Mancini, F.1
Gentiletti, F.2
D'Angelo, M.3
Giglio, S.4
Nanni, S.5
D'Angelo, C.6
Farsetti, A.7
Citro, G.8
Sacchi, A.9
Pontecorvi, A.10
Moretti, F.11
-
57
-
-
0034977277
-
Apaf-1 is a transcriptional target for E2F and p53
-
DOI 10.1038/35078527
-
MC Moroni, ES Hickman, E Lazzerini Denchi, G Caprara, E Colli, F Cecconi, H Muller and K Helin: Apaf-1 is a transcriptional target for E2F and p53. Nat Cell Biol 3(6), 552-8 (2001) (Pubitemid 32536851)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.6
, pp. 552-558
-
-
Moroni, M.C.1
Hickman, E.S.2
Denchi, E.L.3
Caprara, G.4
Colli, E.5
Cecconi, F.6
Muller, H.7
Helin, K.8
-
58
-
-
1842472483
-
Caspase activation inhibits proteasome function during apoptosis
-
DOI 10.1016/S1097-2765(04)00156-X, PII S109727650400156X
-
XM Sun, M Butterworth, M MacFarlane, W Dubiel, A Ciechanover and GM Cohen: Caspase activation inhibits proteasome function during apoptosis. Mol Cell 14(1), 81-93 (2004) (Pubitemid 38469911)
-
(2004)
Molecular Cell
, vol.14
, Issue.1
, pp. 81-93
-
-
Sun, X.-M.1
Butterworth, M.2
MacFarlane, M.3
Dubiel, W.4
Ciechanover, A.5
Cohen, G.M.6
-
59
-
-
0031889132
-
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
-
DOI 10.1038/34214
-
H Sakahira, M Enari and S Nagata: Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391(6662), 96-9 (1998) (Pubitemid 28079223)
-
(1998)
Nature
, vol.391
, Issue.6662
, pp. 96-99
-
-
Sakahira, H.1
Enari, M.2
Nagata, S.3
-
60
-
-
2942581328
-
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain
-
DOI 10.1016/j.cell.2004.05.008, PII S0092867404004969
-
JE Ricci, C Munoz-Pinedo, P Fitzgerald, B Bailly-Maitre, GA Perkins, N Yadava, IE Scheffler, MH Ellisman and DR Green: Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell 117(6), 773-86 (2004) (Pubitemid 38748893)
-
(2004)
Cell
, vol.117
, Issue.6
, pp. 773-786
-
-
Ricci, J.-E.1
Munoz-Pinedo, C.2
Fitzgerald, P.3
Bailly-Maitre, B.4
Perkins, G.A.5
Yadava, N.6
Scheffler, I.E.7
Ellisman, M.H.8
Green, D.R.9
-
61
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
H Li, H Zhu, CJ Xu and J Yuan: Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94(4), 491-501 (1998) (Pubitemid 28391865)
-
(1998)
Cell
, vol.94
, Issue.4
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.-J.3
Yuan, J.4
-
62
-
-
33744963542
-
P53 is cleaved by caspases generating fragments localizing to mitochondria
-
DOI 10.1074/jbc.M512467200
-
BS Sayan, AE Sayan, RA Knight, G Melino and GM Cohen: p53 is cleaved by caspases generating fragments localizing to mitochondria. J Biol Chem 281(19), 13566-73 (2006) (Pubitemid 43855270)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.19
, pp. 13566-13573
-
-
Sayan, B.S.1
Sayan, A.E.2
Knight, R.A.3
Melino, G.4
Cohen, G.M.5
-
63
-
-
0035229427
-
The mitochondrion in apoptosis: How Pandora's box opens
-
DOI 10.1038/35048073
-
N Zamzami and G Kroemer: The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2(1), 67-71 (2001) (Pubitemid 33676964)
-
(2001)
Nature Reviews Molecular Cell Biology
, vol.2
, Issue.1
, pp. 67-71
-
-
Zamzami, N.1
Kroemer, G.2
-
64
-
-
0036083537
-
Molecular structure and physiological function of chloride channels
-
TJ Jentsch, V Stein, F Weinreich and AA Zdebik: Molecular structure and physiological function of chloride channels. Physiol Rev. 82(2), 503-568 (2002) (Pubitemid 34654460)
-
(2002)
Physiological Reviews
, vol.82
, Issue.2
, pp. 503-568
-
-
Jentsch, T.J.1
Stein, V.2
Weinreich, F.3
Zdebik, A.A.4
-
65
-
-
0030176455
-
Chloride channels: A molecular perspective
-
DOI 10.1016/S0959-4388(96)80112-7
-
TJ Jentsch: Chloride channels: a molecular perspective. Curr Opin Neurobiol 6(3), 303-10 (1996) (Pubitemid 26235677)
-
(1996)
Current Opinion in Neurobiology
, vol.6
, Issue.3
, pp. 303-310
-
-
Jentsch, T.J.1
-
66
-
-
0040737617
-
P53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein
-
E Fernandez-Salas, M Sagar, C Cheng, SH Yuspa and WC Weinberg: p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein. J Biol Chem 274(51), 36488-97 (1999)
-
(1999)
J Biol Chem
, vol.274
, Issue.51
, pp. 36488-36497
-
-
Fernandez-Salas, E.1
Sagar, M.2
Cheng, C.3
Yuspa, S.H.4
Weinberg, W.C.5
-
67
-
-
0036098462
-
MtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53
-
DOI 10.1128/MCB.22.11.3610-3620.2002
-
E Fernández-Salas, K Suh, V Speransky, W Bowers, J Levy, T Adams, K Pathak, L Edwards, D Hayes, C Cheng, A Steven, W Weinberg and S. Yuspa: mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol Cell Biol 22(11), 3610-20 (2002) (Pubitemid 34525205)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.11
, pp. 3610-3620
-
-
Fernandez-Salas, E.1
Suh, K.S.2
Speransky, V.V.3
Bowers, W.L.4
Levy, J.M.5
Adams, T.6
Pathak, K.R.7
Edwards, L.E.8
Hayes, D.D.9
Cheng, C.10
Steven, A.C.11
Weinberg, W.C.12
Yuspa, S.H.13
-
68
-
-
0034646626
-
Molecular cloning and characterization of a novel chloride intracellular channel-related protein, parchorin, expressed in water-secreting cells
-
DOI 10.1074/jbc.275.15.11164
-
T Nishizawa, T Nagao, T Iwatsubo, JG Forte and T Urushidani: Molecular cloning and characterization of a novel chloride intracellular channel-related protein, parchorin, expressed in water-secreting cells. J Biol Chem 275(15), 11164-73 (2000) (Pubitemid 30212760)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.15
, pp. 11164-11173
-
-
Nishizawa, T.1
Nagao, T.2
Iwatsubo, T.3
Forte, J.G.4
Urushidani, T.5
-
69
-
-
0033555610
-
Molecular cloning and characterization of a mitogenactivated protein kinase-associated intracellular chloride channel
-
Z Qian, D Okuhara, MK Abe and MR Rosner: Molecular cloning and characterization of a mitogenactivated protein kinase-associated intracellular chloride channel. J Biol Chem 274(3), 1621-7 (1999)
-
(1999)
J Biol Chem
, vol.274
, Issue.3
, pp. 1621-1627
-
-
Qian, Z.1
Okuhara, D.2
Abe, M.K.3
Rosner, M.R.4
-
70
-
-
0036087412
-
CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel
-
BM Tulk, S Kapadia and JC Edwards: CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel. Am J Physiol Cell Physiol 282(5), C1103-12 (2002) (Pubitemid 34663119)
-
(2002)
American Journal of Physiology - Cell Physiology
, vol.282
, Issue.5
-
-
Tulk, B.M.1
Kapadia, S.2
Edwards, J.C.3
-
71
-
-
0036971427
-
Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-β1-mediated conversion of fibroblasts to myofibroblasts
-
L Ronnov-Jessen, R Villadsen, JC Edwards and OW Petersen: Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-beta1-mediated conversion of fibroblasts to myofibroblasts. Am J Pathol 161(2), 471-80 (2002) (Pubitemid 36142156)
-
(2002)
American Journal of Pathology
, vol.161
, Issue.2
, pp. 471-480
-
-
Ronnov-Jessen, L.1
Villadsen, R.2
Edwards, J.C.3
Petersen, O.W.4
-
72
-
-
0345731467
-
A C. elegans CLIC-like Protein Required for Intracellular Tube Formation and Maintenance
-
DOI 10.1126/science.1087667
-
KL Berry, HE Bulow, DH Hall and O Hobert: A C. elegans CLIC-like protein required for intracellular tube formation and maintenance. Science 302(5653), 2134-7 (2003) (Pubitemid 38017948)
-
(2003)
Science
, vol.302
, Issue.5653
, pp. 2134-2137
-
-
Berry, K.L.1
Bulow, H.E.2
Hall, D.H.3
Hobert, O.4
-
73
-
-
1842529559
-
Capturing and profiling adult hair follicle stem cells
-
DOI 10.1038/nbt950
-
RJ Morris, Y Liu, L Marles, Z Yang, C Trempus, S Li, JS Lin, JA Sawicki and G Cotsarelis: Capturing and profiling adult hair follicle stem cells. Nat Biotechnol 22(4), 411-7 (2004) (Pubitemid 38451371)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.4
, pp. 411-417
-
-
Morris, R.J.1
Liu, Y.2
Marles, L.3
Yang, Z.4
Trempus, C.5
Li, S.6
Lin, J.S.7
Sawicki, J.A.8
Cotsarelis, G.9
-
74
-
-
0036098462
-
MtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53
-
DOI 10.1128/MCB.22.11.3610-3620.2002
-
E Fernandez-Salas, KS Suh, VV Speransky, WL Bowers, JM Levy, T Adams, KR Pathak, LE Edwards, DD Hayes, C Cheng, AC Steven, WC Weinberg and SH Yuspa: mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol Cell Biol 22(11), 3610-20 (2002) (Pubitemid 34525205)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.11
, pp. 3610-3620
-
-
Fernandez-Salas, E.1
Suh, K.S.2
Speransky, V.V.3
Bowers, W.L.4
Levy, J.M.5
Adams, T.6
Pathak, K.R.7
Edwards, L.E.8
Hayes, D.D.9
Cheng, C.10
Steven, A.C.11
Weinberg, W.C.12
Yuspa, S.H.13
-
75
-
-
10744231940
-
The Organellular Chloride Channel Protein CLIC4/mtCLIC Translocates to the Nucleus in Response to Cellular Stress and Accelerates Apoptosis
-
DOI 10.1074/jbc.M311632200
-
KS Suh, M Mutoh, K Nagashima, E Fernandez-Salas, LE Edwards, DD Hayes, JM Crutchley, KG Marin, RA Dumont, JM Levy, C Cheng, S Garfield and SH Yuspa: The organellular chloride channel protein CLIC4/mtCLIC translocates to the nucleus in response to cellular stress and accelerates apoptosis. J Biol Chem 279(6), 4632-41 (2004) (Pubitemid 38199055)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4632-4641
-
-
Suh, K.S.1
Mutoh, M.2
Nagashima, K.3
Fernandez-Salas, E.4
Edwards, L.E.5
Hayes, D.D.6
Crutchley, J.M.7
Marin, K.G.8
Dumont, R.A.9
Levy, J.M.10
Cheng, C.11
Garfield, S.12
Yuspa, S.H.13
-
76
-
-
19944431643
-
Antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth
-
KS Suh, M Mutoh, M Gerdes, JM Crutchley, T Mutoh, LE Edwards, RA Dumont, P Sodha, C Cheng, A Glick and SH Yuspa: Antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth. Cancer Res 65(2), 562-71 (2005)
-
(2005)
Cancer Res
, vol.65
, Issue.2
, pp. 562-571
-
-
Suh, K.S.1
Mutoh, M.2
Gerdes, M.3
Crutchley, J.M.4
Mutoh, T.5
Edwards, L.E.6
Dumont, R.A.7
Sodha, P.8
Cheng, C.9
Glick, A.10
Yuspa, S.H.11
-
77
-
-
0028935119
-
Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells
-
S Kimura, T Maekawa, K Hirakawa, A Murakami and T Abe: Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells. Cancer Res 55(6), 1379-84 (1995)
-
(1995)
Cancer Res
, vol.55
, Issue.6
, pp. 1379-1384
-
-
Kimura, S.1
Maekawa, T.2
Hirakawa, K.3
Murakami, A.4
Abe, T.5
-
78
-
-
0026642195
-
Induction of apoptosis in fibroblasts by c-myc protein
-
GI Evan, AH Wyllie, CS Gilbert, TD Littlewood, H Land, M Brooks, CM Waters, LZ Penn and DC Hancock: Induction of apoptosis in fibroblasts by c-myc protein. Cell 69(1), 119-28 (1992)
-
(1992)
Cell
, vol.69
, Issue.1
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
Waters, C.M.7
Penn, L.Z.8
Hancock, D.C.9
-
79
-
-
33751562430
-
Splicing out the west?
-
DOI 10.1126/science.314.5803.1232
-
J Guo and H Xin: Chinese gene therapy. Splicing out the West? Science 314(5803), 1232-5 (2006) (Pubitemid 44846373)
-
(2006)
Science
, vol.314
, Issue.5803
, pp. 1232-1235
-
-
Guo, J.1
Xin, H.2
-
80
-
-
33847065486
-
The Epigenomics of Cancer
-
DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
-
P Jones and S Baylin: The epigenomics of cancer. Cell 128(4), 683-92 (2007) (Pubitemid 46273572)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
81
-
-
0037042177
-
Waf1/Cip1/Sdi1: Association with cell senescence and tumour-promoting activities of stromal fibroblasts
-
DOI 10.1016/S0304-3835(01)00847-3, PII S0304383501008473
-
I Roninson: Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts. Cancer Lett 179(1), 1-14 (2002) (Pubitemid 34195647)
-
(2002)
Cancer Letters
, vol.179
, Issue.1
, pp. 1-14
-
-
Roninson, I.B.1
-
82
-
-
33749845328
-
Mitochondrially targeted wild-type p53 suppresses growth of mutant p53 lymphomas in vivo
-
DOI 10.1038/sj.onc.1209641, PII 1209641
-
G Palacios and U Moll: Mitochondrially targeted wildtype p53 suppresses growth of mutant p53 lymphomas in vivo. Oncogene 25(45), 6133-9 (2006) (Pubitemid 44562412)
-
(2006)
Oncogene
, vol.25
, Issue.45
, pp. 6133-6139
-
-
Palacios, G.1
Moll, U.M.2
-
83
-
-
46749115781
-
Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model
-
G Palacios, H Crawford, A Vaseva and U Moll: Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model. Cell Cycle 7(16), 2584-90 (2008)
-
(2008)
Cell Cycle
, vol.7
, Issue.16
, pp. 2584-2590
-
-
Palacios, G.1
Crawford, H.2
Vaseva, A.3
Moll, U.4
-
84
-
-
67349112742
-
Glucocorticoid receptors and other nuclear transcription factors in mitochondria and possible functions
-
AM Psarra and CE Sekeris: Glucocorticoid receptors and other nuclear transcription factors in mitochondria and possible functions. Biochim Biophys Acta 1787(5), 431-6 (2009)
-
(2009)
Biochim Biophys Acta
, vol.1787
, Issue.5
, pp. 431-436
-
-
Psarra, A.M.1
Sekeris, C.E.2
-
85
-
-
0038418297
-
P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA
-
Y Yoshida, H Izumi, T Torigoe, H Ishiguchi, H Itoh, D Kang and K Kohno: P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA. Cancer Res 63(13), 3729-34 (2003) (Pubitemid 36793059)
-
(2003)
Cancer Research
, vol.63
, Issue.13
, pp. 3729-3734
-
-
Yoshida, Y.1
Izumi, H.2
Torigoe, T.3
Ishiguchi, H.4
Itoh, H.5
Kang, D.6
Kohno, K.7
-
86
-
-
9644277218
-
Identification of a putative p53 binding sequence within the human mitochondrial genome
-
DOI 10.1016/j.febslet.2004.10.099, PII S0014579304013730
-
K Heyne, S Mannebach, E Wuertz, KX Knaup, M Mahyar-Roemer and K Roemer: Identification of a putative p53 binding sequence within the human mitochondrial genome. FEBS Lett 578(1-2), 198-202 (2004) (Pubitemid 39576125)
-
(2004)
FEBS Letters
, vol.578
, Issue.1-2
, pp. 198-202
-
-
Heyne, K.1
Mannebach, S.2
Wuertz, E.3
Knaup, K.X.4
Mahyar-Roemer, M.5
Roemer, K.6
-
87
-
-
0035890849
-
A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53
-
KL Sugars, V Budhram-Mahadeo, G Packham and DS Latchman: A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53. Nucleic Acids Res 29(22), 4530-40 (2001) (Pubitemid 33095013)
-
(2001)
Nucleic Acids Research
, vol.29
, Issue.22
, pp. 4530-4540
-
-
Sugars, K.L.1
Budhram-Mahadeo, V.2
Packham, G.3
Latchman, D.S.4
-
88
-
-
24644457314
-
Complicating the complexity of p53
-
DOI 10.1093/carcin/bgi122
-
KS Yee and KH Vousden: Complicating the complexity of p53. Carcinogenesis 26(8), 1317-22 (2005) (Pubitemid 41430092)
-
(2005)
Carcinogenesis
, vol.26
, Issue.8
, pp. 1317-1322
-
-
Yee, K.S.1
Vousden, K.H.2
-
89
-
-
85047699843
-
Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53
-
DOI 10.1038/sj/onc/1205340
-
JP Mathai, M Germain, RC Marcellus and GC Shore: Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53. Oncogene 21(16), 2534-44 (2002) (Pubitemid 34438106)
-
(2002)
Oncogene
, vol.21
, Issue.16
, pp. 2534-2544
-
-
Mathai, J.P.1
Germain, M.2
Marcellus, R.C.3
Shore, G.C.4
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