In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

Molecular and Cellular Biology

Volumn 24, Issue 15, 2004, Pages 6728-6741

  Erster, Susan ^a   Mihara, Motohiro ^a   Kim, Roger H ^a   Petrenko, Oleksi ^a   Moll, Ute M ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INHIBITOR; CASPASE 3; CYTOCHROME C; DNA; ETOPOSIDE; GENE PRODUCT; MITOCHONDRIAL PROTEIN; PROTEIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN KILLER DR5; PROTEIN NOXA; PROTEIN P53; PROTEIN P53DINP1; PROTEIN PUMA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL FRACTIONATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; GAMMA IRRADIATION; GENE ACTIVATION; GENE INDUCTION; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; THYMUS; TUMOR SUPPRESSOR GENE; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL DEATH; CELL LINE; CELLS, CULTURED; DNA DAMAGE; GENETIC VECTORS; HOMOZYGOTE; HUMANS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYMUS GLAND; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 3242690522     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.15.6728-6741.2004     Document Type: Article

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