Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria

Journal of Biological Chemistry

Volumn 280, Issue 19, 2005, Pages 19166-19176

  Arima, Yoshimi ^a   Nitta, Masayuki ^a   Kuninaka, Shinji ^a   Zhang, Dongwei ^a   Fujiwara, Toshiyoshi ^b   Taya, Yoichi ^c   Nakao, Mitsuyoshi ^d   Saya, Hideyuki ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; PROTEINS; RNA;

APOPTOSIS; CELL DEATH; PROTEIN DEGRADATION; TRANSCRIPTIONAL BLOCKADE;

TUMORS;

ALPHA AMANITIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; PROTEIN P53; RNA POLYMERASE II; AMANITIN; CDKN1A PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA DAMAGE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; RNA INTERFERENCE; TRANSACTIVATION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; ADENOVIRUS; CELL CYCLE G1 PHASE; CELL FRACTIONATION; CELL LINE; CHEMISTRY; DOWN REGULATION; FLUORESCENCE MICROSCOPY; GENETICS; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; PLASMID; PROTEIN TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

ADENOVIRIDAE; AMANITINS; APOPTOSIS; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DOWN-REGULATION; G1 PHASE; HUMANS; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; PHOSPHORYLATION; PLASMIDS; PROTEIN TRANSPORT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA POLYMERASE II; RNA, SMALL INTERFERING; S PHASE; SUBCELLULAR FRACTIONS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 21444432928     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410691200     Document Type: Article

References (56)

1. Oren, M. (1994) Semin. Cancer Biol. 5, 221-227
2. Ko, L. J., and Prives, C. (1996) Genes Dev. 10, 1054-1072
3. Levine, A. J. (1997) Cell 88, 323-331
4. Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., and Tanaka, N. (2000) Science 288, 1053-1058
5. Miyashita, T., and Reed, J. C. (1995) Cell 80, 293-299
6. Oda, K., Arakawa, H., Tanaka, T., Matsuda, K., Tanikawa, C., Mori, T., Nishimori, H., Tamai, K., Tokino, T., Nakamura, Y., and Taya, Y. (2000) Cell 102, 849-862
7. Yu, J., Zhang, L., Hwang, P. M., Kinzler, K. W., and Vogelstein, B. (2001) Mol. Cell 7, 673-682
8. Nakano, K., and Vousden, K. H. (2001) Mol. Cell 7, 683-694
9. Attardi, L. D., Reczek, E. E., Cosmas, C., Demicco, E. G., McCurrach, M. E., Lowe, S. W., and Jacks, T. (2000) Genes Dev. 14, 704-718
10. Shen, Y., and Shenk, T. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8940-8944
11. Hoffman, W. H., Biade, S., Zilfou, J. T., Chen, J., and Murphy, M. (2002) J. Biol. Chem. 277, 3247-3257
12. Caelles, C., Helmberg, A., and Karin, M. (1994) Nature 370, 220-223
13. Haupt, Y., Rowan, S., Shaulian, E., Vousden, K. H., and Oren, M. (1995) Genes Dev. 9, 2170-2183
14. Marchenko, N. D., Zaika, A., and Moll, U. M. (2000) J. Biol. Chem. 275, 16202-16212
15. Mihara, M., Erster, S., Zaika, A., Petrenko, O., Chittenden, T., Pancoska, P., and Moll, U. M. (2003) Mol. Cell 11, 577-590
16. Luo, Z., Zheng, J., Lu, Y., and Bregman, D. B. (2001) Mutat. Res. 486, 259-274
17. Lee, K. B., Wang, D., Lippard, S. J., and Sharp, P. A. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 4239-4244
18. Friedberg, E., Walker, G., and Siede, W. (1995) DNA Repair and Mutagenesis, American Society for Microbiology, Washington, D. C.
19. Andera, L., and Wasylyk, B. (1997) Mol. Med. 3, 852-863
20. Arima, Y., Hirota, T., Bronner, C., Mousli, M., Fujiwara, T., Niwa, S., Ishikawa, H., and Saya, H. (2004) Genes Cells 9, 131-142
21. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001) Nature 411, 494-498
22. Zhang, W. W., Fang, X., Branch, C. D., Mazur, W., French, B. A., and Roth, J. A. (1993) BioTechniques 15, 868-872
23. Kanegae, Y., Lee, G., Sato, Y., Tanaka, M., Nakai, M., Sakaki, T., Sugano, S., and Saito, I. (1995) Nucleic Acids Res. 23, 3816-3821
24. Miyake, H., Kanada, N., Nakamura, H., Kagawa, S., Fujiwara, T., Hara, I., Eto, H., Gohji, K., Arakawa, S., Kamidono, S., and Saya, H. (1998) Oncogene 16, 933-943
25. Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., and Vogelstein, B. (1998) Science 282, 1497-1501
26. Bushnell, D. A., Cramer, P., and Kornberg, R. D. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 1218-1222
27. Nguyen, V. T., Giannoni, F., Dubois, M. F., Seo, S. J., Vigneron, M., Kedinger, C., and Bensaude, O. (1996) Nucleic Acids Res. 24, 2924-2929
28. Ljungman, M., Zhang, F., Chen, F., Rainbow, A. J., and McKay, B. C. (1999) Oncogene 18, 583-592
29. Mitsui, A., and Sharp, P. A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6054-6059
30. Yamaizumi, M., and Sugano, T. (1994) Oncogene 9, 2775-2784
31. Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., and Bonner, W. M. (1998) J. Biol. Chem. 273, 5858-5868
32. Rogakou, E. P., Boon, C., Redon, C., and Bonner, W. M. (1999) J. Cell Biol. 146, 905-916
33. Brooks, C. L., and Gu, W. (2003) Curr. Opin. Cell Biol. 15, 164-171
34. Kastan, M. B., Zhan, Q., el-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., and Fornace, A. J., Jr. (1992) Cell 71, 587-597
35. Okamura, S., Arakawa, H., Tanaka, T., Nakanishi, H., Ng, C. C., Taya, Y., Monden, M., and Nakamura, Y. (2001) Mol. Cell 8, 85-94
36. Khan, Q. A., Dipple, A., and Anderson, L. M. (2002) Mol. Carcinog. 33, 1-8
37. Sherr, C. J., and Roberts, J. M. (1999) Genes Dev. 13, 1501-1512
38. Bloom, J., Amador, V., Bartolini, F., DeMartino, G., and Pagano, M. (2003) Cell 115, 71-82
39. Norbury, C., and Nurse, P. (1992) Annu. Rev. Biochem. 61, 441-470
40. Wang, G., Miskimins, R., and Miskimins, W. K. (2000) Exp. Cell Res. 254, 64-71
41. Komarov, P. G., Komarova, E. A., Kondratov, R. V., Christov-Tselkov, K., Coon, J. S., Chernov, M. V., and Gudkov, A. V. (1999) Science 285, 1733-1737
42. Venot, C., Maratrat, M., Sierra, V., Conseiller, E., and Debussche, L. (1999) Oncogene 18, 2405-2410
43. Blagosklonny, M. V., Demidenko, Z. N., and Fojo, T. (2002) Cell Cycle 1, 67-74
44. Gottifredi, V., Shieh, S. Y., and Prives, C. (2000) Cold Spring Harbor Symp. Quant. Biol. 65, 483-488
45. Banin, S., Moyal, L., Shieh, S., Taya, Y., Anderson, C. W., Chessa, L., Smorodinsky, N. I., Prives, C., Reiss, Y., Shiloh, Y., and Ziv, Y. (1998) Science 281, 1674-1677
46. Lees-Miller, S. P., Godbout, R., Chan, D. W., Weinfeld, M., Day, R. S., III, Barren, G. M., and Allalunis-Turner, J. (1995) Science 267, 1183-1185
47. Levkau, B., Koyama, H., Raines, E. W., Clurman, B. E., Herren, B., Orth, K., Roberts, J. M., and Ross, R. (1998) Mol. Cell 1, 553-563
48. Bornstein, G., Bloom, J., Sitry-Shevah, D., Nakayama, K., Pagano, M., and Hershko, A. (2003) J. Biol. Chem. 278, 25752-25757
49. Reed, S. I. (2003) Nat. Rev. Mol. Cell Biol. 4, 855-864
50. Bendjennat, M., Boulaire, J., Jascur, T., Brickner, H., Barbier, V., Sarasin, A., Fotedar, A., and Fotedar, R. (2003) Cell 114, 599-610
51. Wang, J., and Walsh, K. (1996) Science 273, 359-361
52. Gorospe, M., Wang, X., Guyton, K. Z., and Holbrook, N. J. (1996) Mol. Cell. Biol. 16, 6654-6660
53. Soengas, M. S., Alarcon, R. M., Yoshida, H., Giaccia, A. J., Hakem, R., Mak, T. W., and Lowe, S. W. (1999) Science 284, 156-159
54. Chipuk, J. E., Kuwana, T., Bouchier-Hayes, L., Droin, N. M., Newmeyer, D. D., Schuler, M., and Green, D. R. (2004) Science 303, 1010-1014
55. Shaulian, E., Schreiber, M., Piu, F., Beeche, M., Wagner, E. F., and Karin, M. (2000) Cell 103, 897-907
56. Ljungman, M., and Lane, D. P. (2004) Nat. Rev. Cancer 4, 727-737