Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis

Journal of Biological Chemistry

Volumn 280, Issue 44, 2005, Pages 37169-37177

  Essmann, Frank ^a   Pohlmann, Stephan ^a   Gillissen, Bernhard ^b   Daniel, Peter T ^b   Schulze Osthoff, Klaus ^a   Jänicke, Reiner U ^a,c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELL CULTURE; DNA; ENZYME KINETICS; GENES; IONIZATION; IRRADIATION; TUMORS;

APOPTOSIS; IRRADIATION-INDUCED TRANSLOCATIONS; MITOCHONDRIA; TUMOR SUPPRESSORS;

BIOCHEMISTRY;

DNA TOPOISOMERASE INHIBITOR; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; PROTEIN PUMA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; GENE TARGETING; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; IONIZING RADIATION; IRRADIATION; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN TRANSPORT; STRESS; TRANSACTIVATION; TUMOR RESISTANCE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; ENZYME INHIBITORS; FIBROBLASTS; HUMANS; MICE; MITOCHONDRIA; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; RADIATION, IONIZING; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 27744449741     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502052200     Document Type: Article

References (41)

1. Vogelstein, B., Lane, D., and Levine, A. J. (2000) Nature 408, 307-310
2. Vousden, K. H., and Lu, X. (2002) Nat Rev. Cancer 2, 594-604
3. Bargonetti, J., and Manfredi, J. J. (2002) Curr. Opin. Oncol. 14, 86-91
4. Oren, M. (2003) Cell Death Differ. 10, 431-442
5. Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C. C. (1991) Science 253, 49-53
6. Vousden, K. H., and Prives, C. (2005) Cell 120, 7-10
7. Olivier, M., Eeles, R., Hollstein, M., Khan, M. A., Harris, C. C., and Hainaut, P. (2002) Hum. Mutat. 19, 607-614
8. Owen-Schaub, L. B., Zhang, W., Cusack, J. C., Angelo, L. S., Santee, S. M., Fujiwara, T., Roth, J. A., Deisseroth, A. B., Zhang, W. W., Kruzel, E., and Radinsky, R. (1995) Mol. Cell. Biol. 15, 3032-3040
9. Wu, G. S., Burns, T., McDonald, E. R., 3rd, Jiang, W., Meng, R., Krantz, I. D., Kao, G., Gan, D. D., Zhou, J. Y., Muschel, R., Hamilton, S. R., Spinner, N. B., Markowitz, S., Wu, G., and El-Deiry, W. S. (1997) Nat. Genet. 17, 141-143
10. Bennett, M., Macdonald, K., Chan, S. W., Luzio, J. P., Simari, R., and Weissberg, P. (1998) Science 282, 290-293
11. Soengas, M. S., Alarcon, R. M., Yoshida, H., Giaccia, A. J., Hakem, R., Mak, T. W., and Lowe, S. W. (1999) Science 284, 156-159
12. Johnstone, R. W., Ruefli, A. A., and Lowe, S. W. (2002) Cell 108, 153-164
13. Nechushtan, A., Smith, C. L., Hsu, Y. T., and Youle, R. J. (1999) EMBO J. 18, 2330-2341
14. Desagher, S., Osen-Sand, A., Nichols, A., Eskes, R., Montessuit, S., Lauper, S., Maundrell, K., Antonsson, B., and Martinou, J. C. (1999) J. Cell Biol. 144, 891-901
15. Miyashita, T., Kitada, S., Krajewski, S., Horne, W. A., Delia, D., and Reed, J. C. (1995) J. Biol. Chem. 270, 26049-26052
16. Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., and Tanaka, N. (2000) Science 288, 1053-1058
17. Nakano, K., and Vousden, K. H. (2001) Mol. Cell 7, 683- 694
18. Kannan, K., Amariglio, N., Rechavi, G., Jakob-Hirsch, J., Kela, I., Kaminski, N., Getz, G., Domany, E., and Givol, D. (2001) Oncogene 20, 2225-2234
19. Sax, J. K., and El-Deiry, W. S. (2003) Cell Death Differ. 10, 413-417
20. Moll, U. M., and Zaika, A. (2001) FEBS Lett. 493, 65-69
21. Chipuk, J. E., and Green, D. R. (2003) J. Clin. Immunol. 23, 355-361
22. Erster, S., and Moll, U. M. (2005) Biochem. Biophys. Res. Commun. 331, 843-850
23. Yee, K. S., and Vousden, K. H. (2005) Carcinogenesis 23, 1317-1322
24. Caelles, C., Helmberg, A., and Karin, M. (1994) Nature, 370, 220-223
25. Haupt, Y., Rowan, S., Shaulian, E., Kazaz, A., Vousden, K., and Oren, M. (1997) Leukemia 11, Suppl. 3, 337-339
26. Haupt, Y., Rowan, S., Shaulian, E., Vousden, K. H., and Oren, M. (1995) Genes Dev. 9, 2170-2183
27. Schuler, M., Bossy-Wetzel, E., Goldstein, J. C., Fitzgerald, P., and Green, D. R. (2000) J. Biol. Chem. 275, 7337-7342
28. Chipuk, J. E., Kuwana, T., Bouchier-Hayes, L., Droin, N. M., Newmeyer, D. D., Schuler, M., and Green, D. R. (2004) Science 303, 1010-1014
29. Marchenko, N. D., Zaika, A., and Moll, U. M. (2000) J. Biol. Chem. 275, 16202-16212
30. Mihara, M., Erster, S., Zaika, A., Petrenko, O., Chittenden, T., Pancoska, P., and Moll, U. M. (2003) Mol. Cell 11, 577-590
31. Leu, J. I., Dumont, P., Hafey, M., Murphy, M. E., and George, D. L. (2004) Nat. Cell Biol. 6, 443-450
32. Jänicke, R. U., Engels, I. H., Dunkern, T., Kaina, B., Schulze-Osthoff, K., and Porter, A. G. (2001) Oncogene 20, 5043-5053
33. Jänicke, R. U., Sprengart, M. L., Wati, M. R., and Porter, A. G. (1998) J. Biol. Chem. 273, 9357-9360
34. Brummelkamp, T. R., Bernards, R., and Agami, R. (2002) Science 296, 550-553
35. Essmann, F., Engels, I. H., Totzke, G., Schulze-Osthoff, K., and Jänicke, R. U. (2004) Cancer Res. 64, 7065-7072
36. von Haefen, C., Gillissen, B., Hemmati, P. G., Wendt, J., Guner, D., Mrozek, A., Belka, C., Dörken, B., and Daniel, P. T. (2004) Oncogene 23, 8320-8332
37. Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., and Riccardi, C. (1991) J. Immunol. Methods 139, 271-279
38. Dimri, G. P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E. E., Linskens, M., Rubelj, I., Pereira-Smith, O., Peacocke, M., and Campisi, J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 9363-9367
39. Nemajerova, A., Erster, S., and Moll, U. M. (2005) Cell Death Differ. 12, 197-200
40. Erster, S., Mihara, M., Kim, R. H., Petrenko, O., and Moll, U. M. (2004) Mol. Cell. Biol. 24, 6728-6741
41. Nister, M., Tang, M., Zhang, X.-Q., Yin, C., Beeche, M., Hu, X., Enblad, G., van Dyke, T., and Wahl, G. M. (2005) Oncogene 24, 3536-3573